中原地域의 땅이름 연구 : ‘산, 골, 재’와의 有綠語를 中心으로

조세용,허원욱 건국대학교 중원인문연구소 1997 중원인문논총 Vol.16 No.-

This thesis is a study of place-names in Central area, and focused on the generate-motivation of the following place-names ; 「san」(산=山=mountain), 「kol」(골=壑, 洞=valley, village), 「cε」(재=峙, 峴, 嶺, 岑=mountain pass). A conclusion of this thesis is as follows. 1) A place-name is generated from the natural phenomenon or the objects that is the motive of the place-name. 2) A study of place-names can be assistant-studies that give a lot of aid not only to a study of dialectology and Korean language but also ethnology, history, archaeology, sociology, political science, economics and Korean literature. 3) A place-name is a linguistic property that we are given by our ancestors, and can be a historical property from which we can observe a dialect geographic feature of the area. 5) As time passes by, a place-name is accompanied with phonologic change or semantic change. 6) According to the kind of language, place-names in Central area can be classified as follows ; ① Place-names that are made of pure native language ②made of Chinese character ③ loan of Chinese character in place of native place-names ④ hybrid place-names that are mixed native language and Chinese character ⑤ adapted from Chinese character and than modified. 7) In the Central area, languages of three countries(Koguryo, Packche, silla) are dizzily because they competed fiercely each other in order to occupy this area, and the linguistic force of Koguryo was most powerful even if not longest possession period. The following will prove the facts. ① The meaning of suffix is 'mountain' ; '[mo](뫼), [mi](미)' originated from '[mohje](芼兮)' that was the place-name of Silla(신라=新羅).' '[tal](달)] originated from '[tal](達)' that was the place-name of Koguryo(고구려=高句麗). '[moru](모루)' originated from [moro, moru](模廬, 牟數) that were place-names of Koguryo. ② The meaning of the suffix is 'valley or village' : '[kol](골)' originated from '[hol](忽)' that was the place-name of Koguryo. '[kol]' appears about 160 items that is most frequency. therefore, we can see the linguistic force of Kogurea was most powerful in this area. '[ul](울)' originated from '[puri](夫里) that was the place-name of Packche(백제 = 百濟) '[ton, tan}(돈,단)' originated from '[tan](旦,呑)', [ton](頓)' that were place-names of Koguryo. ③ The meaning of the suffix is 'mountain pass' : '[cε](재)' originated from '[cii](知衣) that was the place-names of Koguryo. '[ki, ci](기,지) originated from [ki/ci](己/, 只, 支) that were place-names of Packche.

항생제 혼합 시멘트 정을 이용한 장관골 감염성 불유합의 이단계 치료

조세현,정순택,박형빈,황선철,하용찬,황인환 대한골절학회 2004 대한골절학회지 Vol.17 No.4

목적: 장관골 감염성 불유합의 치료 시 항생제 혼합 시멘트 정을 이용한 이단계 재건술의 결과를 분석하고자 한다. 대상 및 방법: 1998년 1월부터 2002년 9월까지 장관골 감염성 불유합으로 이단계 재건 수술을 받은 41예 (대퇴골 26예, 경골 15예)를 대상으로 하였다. 일단계 수술에서는 광범위한 변연 절제술, 부골 제거 및 세척술과 기존 고정 장치의 제거 또는 외고정 장치로의 교환을 시행한 후 시공 (dead space)과 불유합 주변 연부조직 내 항생제 혼합 시멘트 정을 삽입하였다. 임상적 감염 증상이 호전된 평균 8.7주 (3주~32주) 후 이단계 재건술로서 Ⅰ군은 내고정 장치 (금속판 5예, 골수강내 금속정 8예), Ⅱ군은 외고정 장치 (Ilizarov 25예, Monofixator 3예)로 각각 고정하고 17예에서는 골내 이동술이나 골 연장술을 시행하였다. 양군 모두 필요한 경우 골 이식과 시멘트 정의 교환을 추가하였다. 추시 기간은 16개월에서 최장 71개월로 평균 45개월 이었다. 치료 결과는 골유합 기간 및 Paley 방법에 의한 방사선상 골유합 상태와 하지 기능으로 평가하였다. 결과: Ⅰ군 13예 전부와 Ⅱ군 28예 중 26예에서 감염의 치료와 골유합을 얻었다. 이단계 재건술 후 골 이식술, 골 소파술, 외고정 핀 교환과 각변형 교정술, 피부 이식 또는 근육 피판 회전술 등의 보조적 시술이 Ⅰ군은 평균 2회, Ⅱ군은 평균 6.2회 추가되었다. 평균 골유합 기간은 Ⅰ군이 19.3주이고 Ⅱ군이 23.1주로 내고정군이 더 빨랐다. 방사선상 Paley 골유합 상태는 Ⅰ군이 우수 8예, 양호 5예이었고, Ⅱ군이 우수 18예, 양호 7예, 보통 1예, 불량 2예 이었다 (p=0.492). 기능적 결과는 Ⅰ군에서 우수 6예, 양호 6예, 보통 1예 이었고, Ⅱ군에서는 우수 10예, 양호 13예, 보통 3예, 불량 2예 이었다 (p=0.267). 결론: 항생제 혼합 시멘트 정의 골수염 치료 효과가 관찰되었으며, 감염이 호전된 후 내고정 장치로 교환해 준 군이 외고정을 유지한 군에 비하여 추가 수술 횟수가 적고, 골유합 기간도 빨랐다. Purpose: To evaluate treatment results between internal na external fixation groups in two-stage reconstruction of infected nonunion of long bones using antibiotics-impregnated cement beads. Materials and Methods: In the first stage, preexisting hardwares were removed and radical debridement was done. The dead space was filled with antibiotics -impregnated cement beads and the nonunion sits was immobilized by external fixation, cast or skeletal traction. In the second stage, all cases were divided into two groups; the nonunion was fixed by internal fixation in group Ⅰ versus external fixation in group Ⅱ. The intervening period between the first and second stage was average 8.7 weeks (range, 3~23 weeks). Results: The follow-up period was average 45 months (range, 16~71 months). Infection control and bone union were achieved in all 13 cases of group Ⅰ. Infection recurred in two of 28 cases in group Ⅱ, one underwent above-knee amputation and the other case was lost in follow-up. The mean number of supportive operations including repeated curettage, augmentation and change of infected pins, angular correction, and soft tissue flap was average 2 and 6.2 times respectively in group Ⅰ and group Ⅱ. Bony union period was average 19.3 and 23.1 weeks in each group. According to Paley's classification, group Ⅰ was similar to group Ⅱ in bony and functional result (p>0.05). Conclusion: Antibiotics-impregnated cement beads provided positive effect on infection control. Internal fixation group showed less number of additional operations and earlier bony union than external fixation group.

중소기업 전자상거래의 활성화전략에 관한 연구

조세형,김승철,정용균 한국중소기업학회 2004 中小企業硏究 Vol.26 No.2

전자상거래에 관한 대부분의 선행연구들은 기업의 전자상거래 채택 및 확산 요인에 초점을 두었으며, 대기업 중심의 자료를 바탕으로 연구가 수행되었다. 그러나, 기업에서의 전자 상거래 활용은 선택이 아닌 기정 사실화되었고 이제는 어떻게 활용하는가에 초점을 두어야할 때이다. 한편, 대기업을 대상으로 한 연구결과가 중소기업에 지침으로 제공되고 있으나, 중소기업이 단순히 대기업의 축소판이 아니며 많은 점에서 고유의 특성을 지니고 있기 때문에 중소기업 자체의 연구가 필요하다. 본 연구는 세 가지 측면에서 전자상거래에 환한 선행연구를 확장한다. 첫째는 많은 선행연구들이 주로 정보기술의 채택 및 확산이란 차원에서 전자상거래를 다루어 온 것에 비하여 본 연구에서는 전자상거래의 실행을 성과와 연관시켜 다룬다. 둘째는 국가경제에 커다란 비중을 차지하고 영향을 미치는 중소기업에 초점을 둔다. 끝으로, 중소기업에 적합한 전자상거래 활성화 전략을 제안하고자 한다. 연구결과 중소기업에 적합한 특유의 전자상거래 활용형태는 없으며, 기업상황에 적합한 활용형태를 찾는 것이 필요할 것으로 보인다. 한편, 정보시스템 성숙도 수준에 따라 IC실행형태가 성과에 미치는 영향에 차이가 있음을 발견하였다. 예를 들어, 비용우위 전략은 성숙도가 낮을수록 가치시스템형 IC는 성숙도가 높을수록 높은 성과를 나타냈다. Business firms are increasingly taking part in online business activities through internet as the size of the e-commerce market is rapidly growing in the recent years. Electronic commerce (EC) activities now become an essential part of the business strategy for survival as well as growth for both large enterprises and small- to medium-sized enterprises (SMEs). Previous studies on e-commerce mostly focused on the factors leading to adoption and diffusion of EC by business firms, and also have been carried out with the data from big enterprises. More often than not, the results obtained from the large business firms are used to provide the guidelines for SMEs. SMEs are, however, different from large business firms in many aspects, and need to be studied on their own. This paper extends the previous researches on EC in three aspects. Firstly, we study the e-commerce issues in the area of implementation in relation to EC performance, beyond the adoption and diffusion of IT technology which has been the research issues in many previous researches. Secondly, we focus on small and medium enterprises which comprise a large portion of national economy with significant influence. Finally, we propose desirable EC strategies for SMEs upon consideration of SMEs' characteristics.

국어의 圓脣母音化 現象에 대한 연구

조세용 건국대학교 중원인문연구소 1995 중원인문논총 Vol.14 No.-

As we examined closely some questions related to the phenomena of round vowelization of Korean language, we could reach the conclusion as the following: 1. The phenomena of round vowelization are included in the vocable category of phonetic changes with which signifying the external form of language signs among the diachronic realities about the phonemes. 2. The phenomena of round vowelization are the phonetic environments, and they also are the conditioned changes from ?? vowel of -round, which forms the round vocal correlation influenced by main assimilators like labial consonants ?? vowel of +round of progress and imperfect assimilation. 3. The close examinations of assimilation factors of ?? can't be get only with the poor phonetic demonstrations of modern modulation. However, it is considered that it can be examined closely with the nature demonstration of modulation phonetics on the basis of explanatory diagram of the Korean script. 4. The times in which round vowelization had been materialized can be divided into three periods: The first period, from the beginning of fifteenth century to the end of sixteenth century, is that of fomentation. The second, of which during the end of sixteenth century, is that of a productive growth. finally, the third, during the eighteenth century, is of the genuine generation. 5. The phenomenon of ?? must be regarded as universal phonological one of its conditioned change subjected to the influence of the phonetic environments. 6. The phenomena of round vowelization must be considered that it has only progressive assimilation.

「龍飛御天歌」에 나타난 表記法 硏究

趙世用 건국대학교 중원인문연구소 1998 중원인문논총 Vol.17 No.-

This thesis is a study of orthography in 「Yongbiochonga」that was published in 1445 A.D. A conclusion of this thesis is as follows. 1) In the study of Korean linguistics history, a study of orthography in 「Yongbiochonga」 is very important. Because 「Yongbiochonga」 shows us that the King Se-Jong was morphologist. 2) Generally, in 「Yongbiochonga」, the law of 'the final spelling can be used in the position of the first(終聲復用初聲)' is completely keeped. But we can see some 'eight finalsounds law(八終聲法)' (Eight final sounds are /ㄱ, ㄴ, ㄷ, ㄹ, ㅁ, ㅂ, ㅅ, ㅇ/.), that is phonemic spelling style, for example 「맛디, 몃, 닛디」 is found, that's original final spelling is /ㅈ/. 3) Above fact shows us that the King Se-Jong did not completely investigate 「Yongbiochonga」 after the accomplishment of the volume, so phonemic spelling style of Chiphynjon(集賢殿) scholars appears in the volume. 4) Adnominal interval sound 'ㄱ, ㄷ, ㅂ, ㅅ,ㅿ,ㆆ ' were used variously and precisely, that deserves adnominal-case in the morphological aspect. 5) in 「Yongbiochonga」, 'connective spelling law(連綴)' was completely keeped. It shows that Chiphyonjon scholars' phonemic view of grammar came into effect. 6) In my opinion, the Chinese-sound in 「Yongbiochonga」 is mixed "inherited Korean Chinese-sound', '「Dongkukchongun(東國正韻)' Chinese sound」' and 'Mandarin's sound'.

아마릴 정(글리메피리드 2㎎)에 대한 글리메드 정의 생물학적 동등성

조혜영,박은자,강현아,백승희,이석,김세미,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.2

The purpose of the present study was to evaluate the bioequivalence of two glimepiride tables, Amaryl^(?)(Handok/Aventis Pharm. Co., Ltd.) and Glimed (Kuhn Ⅱ Pharm. Co., Ltd.), according to the guidelines of Korea Food and Drug Administration (KFDA). The glimepiride release from the two glimepiride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solution, water and blend of PSB 80 into each dissolution medium). Twenty six healthy male subjects, 22.65±2.19 years in age and 66.55±8.85 kg in body weight, were divided into two groups and randomized 2×2 cross-over study was employed. After one tablet containing 2 ㎎ as glimepiride was orally administered, blood was taken at predetermined time intervals and the concentrations of glimepiride in serum were determined using HPLC method with UV detctor. The dissolution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC_(t), C_(max) and untransformed T_(max). The results showed that the differences between two formulations based on the Amaryl were -3.70, -8.28 and 0.61% for AUC_(t), C_(max) and T_(max), respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically transformed data were within the acceptance range of log(0.8) to log(1.25)(e.g., log(0.84)∼log(1.04) and log(0.82)∼log(1.03) for AUC_(t) and C_(max), respectively). Thus, the criteria of the KFDA guideline for the bioequivalence were satisfied, indicating Glimed tablet and Amaryl tablet were bioequivalent.

웹데이터베이스를 이용한 기업정보화의 전략적 추진에 관한 연구

조세형,김용원 한국정보전략학회 1999 한국정보전략학회지 Vol.2 No.1

The Internet and World Wide Wed(WWW) hold many possibilities for the strategic use of global information technology in the business dimension including business informatization. The proliferation of the Internet and on-line information services has resulted in the integration environment of distribuied computing resources, especially databases. WWW, a hypermedia system for browsing and retrieving Internet resources, use gateway technology to integrate distrbuted databases on platform-independent architecture. In this paper, we present a conceptual model of business information system based on Web DB. The model suggests WWW-based business computing that is already seen as a new competitive business weapon. Finally, prerequisite conditions are consedered for the successful use of this model.

인위적인 원형질막과 세포내 저밀도막의 접합에 미치는 제4형 당운반체 단백질의 전이 및 조절인자에 대한 연구

조용욱,김창세,Paul F. Pilch 순천향대학교 1994 논문집 Vol.17 No.2

We tried to induce the fusion of plasma membrane and intracellular low density microsomal membrane, and evaluated about the regulatory factors(insulin, cytosol, ATP, GTP, incubation time and temperature) which may affect the fusion and movement of the glucose transporter 4(GLUT 4). We obtained the results as follows; 1) Membrane-associated fusion might be fairely well established, and we could confiremd that fact by western analysis. 2) Insulin stimulated the fusion and movement of the GLUT 4. 3) Cytosol showed the tendency to increase the fusion and movement of the GLUT 4, but its effect was not apparent. 4) Other regulatory factor such as ATP, GTP, incubation time and temperature did not affect to the fusion and movement of the GLUT 4. 5) There might be somewhat non-specific reaction when separate the plasma mem-brane and intracellular low density microsomal membrane after fusion. In conclusion, insulin apparently stimulated the fusion and movement of the GLUT 4, but ATP, GTP, incubtion time and temperature did not. Further study to reseparate more specifically the PM and LDM after fusion must be required to clarify the exact effects of various regulatory factors. Acknowledgments : The author thanks Prof. Paul F. Pilch for advice about manu-script and supply the monoclonal antobody of GLUT 4(1F8).

비유피-4 정(염산프로피베린 20㎎)에 대한 건일염산프로피베린 정의 생물학적동등성

조혜영,박은자,강현아,백승희,김세미,박찬호,오인준,문재동,이용복 한국약제학회 2004 Journal of Pharmaceutical Investigation Vol.34 No.5

The purpose of the present study was to evaluate the bioequivalence of two propiverine hydrochloride tablets. BUP-4 (Jeil Pharm. Co., Ltd.) and Kuhnil Propiverine Hydrochloride (Kuhnil Pharm. Co., Ltd.), according to the guidelines of the Korea Food and Drug Administration (KFDA). The propiverine release from the two propiverine hydrochloride formulations in vitro was tested using KP Ⅷ Apparatus Ⅱ method with a variety of dissolution media (pH 1.2, 4.0, 6.8 buffer solutions, water and blend of polysorbate 80 into pH 6.8). Twenty six healthy male subjects, 23.73 ± 2.79 years in age and 67.04 ± 7.93 kg in body weight, were divided into two groups and a randomized 2 x 2 cross-over study was employed. After one tablet containing 20 mg as propiverine hydrochloride was orally administered, blood was taken at predetermined time intervals and the concentrations of propiverine in serum were determined using HPLC method with UV detector. The dis-solution profiles of two formulations were similar at all dissolution media. Besides, the pharmacokinetic parameters such as AUC" C _(max) and T _(max) were calculated and ANOVA test was utilized for the statistical analysis of the parameters using logarithmically transformed AUC, C_(max), and untransformed T_(max). The results showed that the differences between two formulations based on the BUP-4 were 0.17%, 7.98% and 4.55% for AUC,, C_(max), and respectively. There were no sequence effects between two formulations in these parameters. The 90% confidence intervals using logarithmically trans-formed data were within the acceptance range of log(0.8) to log(1.25) (e.g., log(0.88)-log(l .12) and log(0.90)-log(l.15) for AUC, and _(max), respectively). Thus, the criteria of the KFDA bioequivalence guideline were satisfied, indicating Kuhnil Propiverine Hydrochloride tablet was bioequivalent to BUP-4 tablet.

15세기 國語의 語形變化에 대한 通時的 硏究 : with special reference to the noun class 名詞類를 中心으로

조세용 건국대학교 중원인문연구소 1996 중원인문논총 Vol.15 No.-

1) Of the 15th centuries' Korean, the morph changes in the noun class have two kinds of style: one is the change due to the phonemic system change, and the other due to the phonological change. 2) There are two factors of morph changes due to the phonemic system change: one is the expiration of ?? in 15th centuries' phonemic system, and the other is also expiration and change of initial consonant cluster in them. 3) Of morph changes due to the phonological change, there are one occurred by combinative relation and the other by conjunctive relation of the other morpheme. 4) Among the morph change occurred by combinative relation, there are assimilation, contraction, and elision due to the economic efforts of pronunciation. There are also some changes by an effort to make expressions clear; dissimilation, addition, reinforcement, and false regression. Finally, there are changes by unconscious mistakes: transposition and mutual alternation. 5) Of the changes occurred by conjunctive relation of the other morpheme there are; analogy folk etymology, metanalysis and blending.