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      • Research on Granular Computing Approach in Rough Set

        Jin Dai,Feng Hu,Yi Yan 보안공학연구지원센터(IJSIP) 2014 International Journal of Signal Processing, Image Vol.7 No.6

        Granulation of information appears in many areas, such as machine learning, evidence theory, and data mining. Granular computing is the core research field in granulation of information. It is an effective tool for complex problem, massive data mining and fuzzy information processing. In the basis of principle of granularity, we aim to study the granular decomposing method in granules space based on rough set. Moreover, the criteria conditions for attribution necessity and attribute reduction are proposed. Finally, the corresponding equivalence is proved to traditional rough set theory. It will lay the foundation for attribute reduction under the granular representation in rough set.

      • KCI등재

        A new macro-micro dual drive parallel robot for chromosome dissection

        Jin Feng,Feng Gao,Xianchao Zhao,Yi Yue,Renqiang Liu 대한기계학회 2012 JOURNAL OF MECHANICAL SCIENCE AND TECHNOLOGY Vol.26 No.1

        This paper presents a parallel-structure system dually driven by six servo motors and six piezoelectric actuators. Due to the combination of macro and micro manipulators which are both of orthogonal structures, the proposed system possesses a concise structure as well as actuation isolation and output motion decoupling properties. By using a glass needle mounted on a six-dimensional force sensor in endpoint operating, this system can be applied to chromosome dissection that to make the whole process more efficient and automatic. The glass needle tip has a stroke of 106 mm in three linear motions and 18.7-arc-degrees in three angle motion directions, with servo motors adopted. It also has the resolution of 20 nanometers with the adoption of piezoelectric actuators. The kinematics, isotropy, decoupling and design considerations of the proposed robot are discussed. Workspace and resolution of both macro and micro manipulators are measured separately. The experiments are also conducted to show its capability in dissecting chromosomes.

      • ELSEVIER : Synthesis of novel 5-oxaprotoberberines as bioisosteres of protoberberines

        ( Yi Feng Jin ),( Daulat Bikram Khadka ),( Su Hui Yang ),( Chao Zhao ),( Won Jea Cho ) 전남대학교 약품개발연구소 2014 약품개발연구지 Vol.23 No.-

        5-0xaprotoberberinones and 5-oxaprotoberberinium were synthesized as bioisosteres of protoberberines. 5-0xaprotoberberinones were prepared by linking phenol with the isoquinolone ring of 3-phenoIisoquinoIones by methyleneoxy bridge, while the quaternary 5-oxaprotoberberinium salt was synthesized by reduction and oxidation of the lactam moiety of 5-oxaprotoberberinone. ⓒ 2014 Elsevier Ltd. All rights reserved.

      • KCI등재

        Novel AgCl/Ag2SO3 Hybrids as a Visible-Light-driven Photocatalyst: Preparation, Characterization, and Degradation of Rhodamine-B and Methyl Orange

        Xiang-Feng Wu,Yi-Jin Wang,Zuo-Lin Cao,Yan-Mei Feng,Hui Li,Chen-Xu Zhang,Jun-Zhang Su,Jia-Rui Zhang,Yi-Wei Wang,Kai-Yuan Wang,Guo-Wen Sun 대한화학회 2018 Bulletin of the Korean Chemical Society Vol.39 No.7

        The novel AgCl/Ag2SO3 hybrids as an efficient photocatalyst had been fabricated by an in situ synthetic method. The correlations between the structure and the photocatalytic properties of the as-fabricated hybrids were analyzed. Experimental results exhibited that with increasing the amount of Ag2SO3, the degradation rate of the as-obtained samples was firstly increased and then decreased under the visible light irradiation. When the mass ratio of AgCl to Ag2SO3 was 1:2, in 30?min, it displayed the highest degradation rate of 99.2% for rhodamine-B, which was obviously higher than 46.1, 60.5, and 14.6% of pure AgCl, Ag2SO3, and TiO2 (P25), respectively. Similar results could be found in degradation of methyl orange. It had the maximum of 97.4% in 90?min, which was higher than 55.2, 48.7, and 12.7% of pure AgCl, Ag2SO3, and P25, respectively. Moreover, the as-prepared hybrids possessed the enhanced separation and transfer of photo-generated electron?hole pairs compared to the pure samples. In addition, the holes and superoxide radicals played the dominant role and the hydroxyl radicals played the secondary role during the process of photocatalytic degradation.

      • KCI등재

        Causal Relations between Exposome and Stroke: A Mendelian Randomization Study

        Hong-Qi Li,Yi-Wei Feng,Yu-Xiang Yang,Xin-Yi Leng,Prof Can Zhang,Shi-Dong Chen,Kevin Kuo,Shu-Yi Huang,Xue-Qing Zhang,Yi Dong,Xiang Han,Xin Cheng,Mei Cui,Lan Tan,Qiang Dong,Jin-Tai Yu 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.2

        Background and Purpose To explore the causal relationships of elements of the exposome with ischemic stroke and its subtypes at the omics level and to provide evidence for stroke prevention. Methods We conducted a Mendelian randomization study between exposure and any ischemic stroke (AIS) and its subtypes (large-artery atherosclerotic disease [LAD], cardioembolic stroke [CE], and small vessel disease [SVD]). The exposure dataset was the UK Biobank involving 361,194 subjects, and the outcome dataset was the MEGASTROKE consortium including 52,000 participants. Results We found that higher blood pressure (BP) (systolic BP: odds ratio [OR], 1.02; 95% confidence interval [CI], 1.01 to 1.04; diastolic BP: OR, 1.03; 95% CI, 1.01 to 1.05; pulse pressure: OR, 1.03; 95% CI, 1.00 to 1.06), atrial fibrillation (OR, 1.18; 95% CI, 1.13 to 1.25), and diabetes (OR, 1.13; 95% CI, 1.07 to 1.18) were significantly associated with ischemic stroke. Importantly, higher education (OR, 0.69; 95% CI, 0.60 to 0.79) decreased the risk of ischemic stroke. Higher systolic BP (OR, 1.06; 95% CI, 1.02 to 1.10), pulse pressure (OR, 1.08; 95% CI, 1.02 to 1.14), diabetes (OR, 1.28; 95% CI, 1.13 to 1.45), and coronary artery disease (OR, 1.58; 95% CI, 1.25 to 2.00) could cause LAD. Atrial fibrillation could cause CE (OR, 1.90; 95% CI, 1.71 to 2.11). For SVD, higher systolic BP (OR, 1.04; 95% CI, 1.00 to 1.07), diastolic BP (OR, 1.06; 95% CI, 1.01 to 1.12), and diabetes (OR, 1.22; 95% CI, 1.10 to 1.36) were causal factors. Conclusions The study revealed elements of the exposome causally linked to ischemic stroke and its subtypes, including conventional causal risk factors and novel protective factors such as higher education.

      • Behavior of hybrid CFST with FRP-confined UHPC core under axial compression

        Yi Tao,Jin-Ben Gu,Jian-Fei Chen,Peng Feng 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.1

        A fiber-reinforced polymer (FRP)-confined concrete core that provides high strength and ductility under axial compression can act as strength enhancement in a hybrid column. In the present study, ordinary concrete was replaced with ultra-high-performance concrete (UHPC) to form an FRP-confined UHPC core (FCUC). The FCUC was embedded in square concrete-filled steel tube (CFST) columns to form a high-performance hybrid column (SCF-UHPC column for short). The axial compressive behavior of the SCF-UHPC was experimentally investigated using 12 SCF-UHPC columns and two ordinary CFST columns for comparison. The advantages of the SCF-UHPC include excellent axial load-bearing capacity, good ductility, and stable residual load-bearing capacity. The results show that failure of an SCF-UHPC column was caused by FRP rupture of FCUC, which occurred after steel tube buckling that results in the degraded stiffness. It was also shown that the load-displacement behavior of the SCF-UHPC composite column was determined by the UHPC core diameter and the corresponding confinement provided by the outer steel tube and inner FRP jacket. A hardening effect could be achieved when the confinement demand of the UHPC core was satisfied, whereas a plateau effect appeared if the confinement was insufficient. Furthermore, the load-bearing capacity and ductility of the SCF-UHPC columns improved with increased thickness of the steel tube and the FRP.

      • Effect of Grape Procyanidins on Tumor Angiogenesis in Liver Cancer Xenograft Models

        Feng, Li-Li,Liu, Bing-Xia,Zhong, Jin-Yi,Sun, Li-Bin,Yu, Hong-Sheng Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

        Background: In recent years a wide variety of flavonoids or polyphenolic substances have been reported to possess substantial anti-carcinogenic and antimutagenic activities. Grape proanthocyanidins (GPC) are considered as good examples for which there is evidence of potential roles as anti-carcinogenic agents. Methods: A xenograft model was established using H22 cells subcutaneously injected into mice and used to assess different concentrations of grape proanthocyanidins (GPC) and Endostar. Treatments were maintained for 10 days, then levels of vascular endothelial growth factor (VEGF) and microvessel density (MVD) were examined by immunohistochemistry, while VEGF mRNA was determined by real-time PCR in tumor tissue. Results: The expression of MVD and VEGF decreased gradually as the concentration of GPC increased.There was a significant positive correlation between MVD and VEGF. Conclusions: These results suggest that GPC restrains the growth of tumor, possibly by inhibiting tumour angiogenesis.

      • SCIESCOPUS

        Periodic seismic performance evaluation of highway bridges using structural health monitoring system

        Yi, Jin-Hak,Kim, Dookie,Feng, Maria Q. Techno-Press 2009 Structural Engineering and Mechanics, An Int'l Jou Vol.31 No.5

        In this study, the periodic seismic performance evaluation scheme is proposed using a structural health monitoring system in terms of seismic fragility. An instrumented highway bridge is used to demonstrate the evaluation procedure involving (1) measuring ambient vibration of a bridge under general vehicle loadings, (2) identifying modal parameters from the measured acceleration data by applying output-only modal identification method, (3) updating a preliminary finite element model (obtained from structural design drawings) with the identified modal parameters using real-coded genetic algorithm, (4) analyzing nonlinear response time histories of the structure under earthquake excitations, and finally (5) developing fragility curves represented by a log-normal distribution function using maximum likelihood estimation. It is found that the seismic fragility of a highway bridge can be updated using extracted modal parameters and can also be monitored further by utilizing the instrumented structural health monitoring system.

      • Significance of Expression of Human METCAM/MUC18 in Nasopharyngeal Carcinomas and Metastatic Lesions

        Lin, Jin-Ching,Chiang, Cheng-Feng,Wang, Shur-Wern,Wang, Wen-Yi,Kwan, Po-Cheung,Wu, Guang-Jer Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.1

        Human METCAM/MUC18, a cell adhesion molecule (CAM) in the immunoglobulin-like gene super family, plays a dual role in the progression of several epithelium cancers; however, its role in the nasopharyngeal carcinoma (NPC) remains unclear. To initiate the study we determined human METCAM/MUC18 expression in tissue samples of normal nasopharynx (NP), NPCs, and metastatic lesions, and in two established NPC cell lines. Immunoblotting analysis was used for the determination in lysates of frozen tissues, and immunohistochemistry (IHC) for expression in formalin-fixed, paraffin-embedded tissue sections of 7 normal nasopharynx specimens, 94 NPC tissue specimens, and 3 metastatic lesions. Human METCAM/MUC18 was expressed in 100% of the normal NP, not expressed in 73% of NPC specimens (or expressed at very low levels in only about 27% of NPC specimens), and expressed again in all of the metastatic lesions. The level of human METCAM/MUC18 expression in NPC tissues was about one fifth of that in the normal NP and metastatic lesions. The low level of human METCAM/MUC18 expression in NPC specimens was confirmed by a weak signal of RT-PCR amplification of the mRNA. Low expression levels of human METCAM/MUC18 in NPC tissues were also reflected in the seven established NPC cell lines. These findings provided the first evidence that diminished expression of human METCAM/MUC18 is an indicator for the emergence of NPC, but increased expression then occurs with metastatic progression, suggesting that huMETCAM/MUC18, perhaps similar to TGF-${\beta}$, may be a tumor suppressor, but a metastasis promoter for NPC.

      • KCI등재

        Synthesis of large diameter plat-like Ca3Co4O9 particle by molten salt method

        Ningbo Feng,Yingrong Jin,Sujun Guan,Yi He,Liang Hao,Yun Lu 한양대학교 세라믹연구소 2016 Journal of Ceramic Processing Research Vol.17 No.10

        The Ca3Co4O9 was synthesized by molten salt method using CoO, CaCO3 and CaCl2 as stating materials. The thermal behaviorwas investigated by directly measuring and comparing the temperatures of the mixture and reference material simultaneously. The obtained compounds were characterized by XRD, SEM and EDS. The results showed that CaCO3 and CaCl2 form amolten salt solution at about 628 oC. The highly c axis oriented plat-like Ca3Co4O9 particles were obtained at 800 oC for 4 hrsand the Ca3Co4O9 particles reaches about 300 µm in diameter and 20 µm in thickness. The template formation processdominates the nucleation of Ca3Co4O9 and the shape transformation to plat-like shape has happened in the growth ofCa3Co4O9 nuclei.

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