孤山 尹善道의 時調에 나타난 思想性 硏究

柳年錫,崔美愛 순천대학교 과학교육연구소 2001 科學과 敎育 Vol.9 No.-

In this thesis, we researched the thought in Gosan Yun Seon-do’s Sijo to appreciate his works entirely. After we looked into his life, looked around the situation of his time, and observed the characteristics of his literary works, the thought which was appeared in his Sijo could be summarized as follows: First, his life was full of ups and downs with his intense patriotism during his life 85 years. He had troubles both at home and abroad, such as invasions, party disputes. He went into exile, entered government office, and retired from the world. Second, his trend of ideology was based on Confucian ideas. He accepted various ideas, such as Taoism, Buddhism, Shamanism. He considered that the government and the nature were the same thing. He inclined the love for king through his life. Third, his literature took root in confucian and moral ethics. He thought that the literature was the means of instruction and special purpose. His view of nature and music was based on Confucian morality. Fourth, most of his Sijo included the contents of instruction, admonition, and patriotism to realize confucian idea containing royalty and filial piety. We showed the trend of Gosan Yun Seon-do’s thought in his Sijo through his life idea, literature, nature, and music. We think that it deserves to help the investigation of Gosan literature and we look forward to study his works con tinually in various point of view.

初等學校 傳記文의 人物과 內容

柳年錫,金美愛 順天大學校 師範大學 附屬 科學敎育硏究所 1999 科學과 敎育 Vol.7 No.-

If education is thought to be essentially implemented through an identification process, a figure whose biography is included in textbook should be a good example of whom children can follow. In addition, biography should be described in such a lively way that children can involuntarily find it interesting to read it and be moved by it. When considering such an educational significance and inherent characteristic of biographical writing, there was a doubt about whether figures and contents of biographical writings included in textbook could virtually generate identification effect. To address the problem, figures included in the biography unit of the Korean language reading textbook of the 6th elementary curriculum were analyzed by achievement, period and gender. Then the Korean language textbook was analyzed b y theme, and an attempt to find out the problems of figure description was made to define figure selection criteria. The findings of this study were as follows: 23 persons were included in the biography unit of the current reading textbook. One of the problems was that the dominant type of figure among them was the males of our country, who were chiefly a Confucian scholar or a politician, or devoted their lives to national independence movement, in the Choson Age or under the reign of Japan. By theme, 8 figures(35%) were allocated to the theme of love for the nation. This suggested there was a fixed idea that identified national goal with personal goal. Besides, those figures were described as being extraordinarily remarkable and superhuman in childhood. This sort of description got children to have a feeling that they were too distant to follow. It seemed better to prepare biography to inspire a self-confidence that even an ordinary man could be a good man if he tried hard. Thus, this study focused on winning children's sympathies, by encouraging teachers to have the right view of biography teaching and using a learner-centered teaching plan providing direct experience. It's hoped that this study would be employed as one of biography teaching methods that children might find interesting.

일부 임상간호사들의 직무스트레스와 우울과의 관련성

이미옥,류소연,변익건,박정희 朝鮮大學校 附設 醫學硏究所 2004 The Medical Journal of Chosun University Vol.29 No.2

Objective : This study was performed to identify the relationship between job stress and depression of nurses who work at hospitals in Gwangju city. Methods : The data were collected from October 2 to 22, 2003 using the self-administered questionnaire which was composed demographic characteristics, job-related factors, health-related factors, family-related factors, job stress, self-esteem and Korean Beck's depression inventory. The statistic methods were t-test, analysis of variance (ANOVA), Pearson's correlation analysis and multiple regression analysis. Results : 1. The score of job stress of clinical nurses was 169.23 (24.44) , and depression point was 11.37 (7.71). By the depression criteria, the prevalence of depression were 11.2% in pre-depression, 5.7% in moderate and 4.6% in severe depression. 2. It was found that the characteristics that had a statistically significant relation with depression scores were age, marital status, educational background, career, income, drinking status, satisfaction in living and self-esteem. And job stress was statistically significant positive correlation with depression scores. 3. As a result of multiple regression analysis, the job stress had not a statistically significant relation with depression with controlled other related factors. Conclusion : It is necessary to prepare the program about the control and prevention of depression In clinical nurses. Further study need to identify the relationship between depression and job-related factors in nurses working at the hospitals.

간호사의 이직의도와 관련요인

윤미숙,김진선,류소연,김기순 조선대학교 부설 의학연구소 2002 The Medical Journal of Chosun University Vol.27 No.1

Objectives: The purposes of this study were to identify the nurses' turnover intention and its related factors, and to identify the predictors of nurses' turnover intention. Method: Data were collected from 211 nurses who working in a general hospital in Gwangju using structured questionnaires. Results: Nurses expressed moderate level of turnover intention. Nurses' turnover intention was significantly different by their age, position, night duty, and size of the working place. Job related variables such as job characteristics, job satisfaction, and organizational commitment were significantly related to nurses' turnover intention. Nurses who reported higher autonomy, diversity, higher job satisfaction, and higher organizational commitment reported lower turnover intention than their counterparts. There were significant positive correlations between job characteristics, job satisfaction, and organizational commitment. Job satisfaction and organizational commitment were identified as statistically significant predictors of nurses' turnover intention and these two variables explained 35% of the variance of turnover intention. Conclusion: This study identified the importance of job satisfaction and organizational commitment to predict the nurses' turnover intention. Interventions which improve job satisfaction and organizational commitment of nurses may prevent or reduce nurses' turnover rate. To identify causal relationships of nurses' turnover and its related factors, more research is needed.

참외 흰가루병에 대한 살균제의 예방 및 치료효과 검정

장태현,류연주,임혜정,임수진,최미영,정병룡,김철웅,이용세 한국환경농학회 2006 한국환경농학회지 Vol.25 No.1

요로결석 환자의 체외충격파쇄석술 치료경과와 결석 특성과의 관련성

김성길,김기순,류소연,한미아,이선옥,노준 朝鮮大學校 附設 醫學硏究所 2009 The Medical Journal of Chosun University Vol.33 No.S

요로 결석에 대한 비 침습적 치료 방법인 체외충격파쇄석술에 의한 치료경과와 결석 특성과의 관련성을 파악키 위해 2002년 12월부터 2008년 3월까지 G시 H병원에서 요로 결석으로 진단되어 체외충격파쇄석술을 받은 33l례를 대상으로 의무기록 자료를 이용하여 분석한 결과는 다음과 같다. 1. 조사 대상자 331례중 남자는 68.6%, 여자는 31.4%이었으며 평균연령(표준편차)은 44.2 (13.9)세 이었고 84%가 G시내 거주자였다. 2. 조사 대상자에게 시행된 체외충격파쇄석술의 평균 시술횟수(표준편차)는 1.9(1.5)회 이었으며 평균 통증제거기간(표준편차)은 3.2(2.1)일 이었고 요로결석 진단 시로부터 치료가 완료되었다고 의사가 판정했을 때까지의 치료기간의 평균(표준편차)은 10.3(8.4)일 이었다. 3. 시술횟수에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석크기, 결석의 방사선 투과성, 요관 폐색여부 이었으며 모형의 설명력은 13.5%이었다. 4. 통증제거기간에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석의 방사선 투과성 이었으며 모형의 설명력은 7.4%이었다. 5. 치료기간에 통계적으로 유의하게(P<0.01) 관련된 요인은 결석크기와 결석의 방사선 투과성 이었으며 모형의 설명력은 13.5%이었다. 따라서 결석의 크기가 크거나 결석이 방사선에 비 투과성일 때, 요관이 폐색되어 있을 때 치료경과가 늦게 됨으로 이러한 사실을 참고 하여 추후 진료지침을 작성 시 보다 효과적이고 효율적인 치료법을 적용할 필요가 있다고 판단되며 보다 체계적인 평가와 연구가 필요할 것이다. Objectives & Methods: To find the treatment process by extracorporeal shock wave lithotripsy (ESWL) and its related stone characteristics in urinary tract stone patients, an analysis was done from medical records of 331 cases who were treated by ESWL from December 2002 to March 2008 at H hospital in G city. Results: Among 331 study subjects 68.6% were male and 31.4% were female. Their mean age (standard deviation, SD) was 44.2 (13.9) years old and 84.0% lived in G city. Average frequency of ESWL done toward study cases were 1.9±1.5 times. Mean duration of disappearance from pain was 3.2±2.1 days and total treatment period for a stone was 10.3±8.4 days. Statistically significant (p<0.01) stone and urinary tract characteristics related with frequency of ESWL were stone size, radio-opacity of the stone, and obstruction of urinary tract. The model composed of these 3 independent variables explained 13.5% of frequency of ESWL. Statistically significant (p<0.01) variable related with disappearance from pain was radio-opacity of the stone, and this model explained 7.4%. Statistically significant (p<0.01) variables related with treatment duration due to stone were stone size and radio-opacity of the stone. These two variables explained 13.5%. Conclusion: The bigger the size of stone are, the slower the treatment process will be. And when the stone is radio-opaque and urinary tract is obstructed, the treatment process will be slower than stone is radio-luscent and urinary tract is not obstructed. So to make effective and efficient treatment manual for ESWL, above fact must be considered and continuous systematic evaluation and research toward ESWL are necessary.

건강가정지원센터 가정생활교육 프로그램 운영 및 성과 : 용산구·숙명여자대학교 시범사업을 중심으로

김명자,계선자,박미석,장진경,김연화,한은주,류진아 한국가족관계학회 2005 한국가족관계학회지 Vol.10 No.1

The purpose of this study is to propose a model for service programs and management strategies for the division of family education in Healthy Families Center. For the purpose, the researchers find out demands for the family education programs of people in Yong-San Gu, Seoul, exam the effect of each family education program of Yong-San Gu & Sookmyung Women's University Healthy Families Center from June to December, 2004. According to the results, people in Yong-San Gu need economic education service mostly, and they want to study at Saturday afternoon. The programs show positive effect on the improvement of family health.

Development of highly infectious in vitro transcription vector of non-aphid-transmissible CFP-tagging clone of Pepper mottle virus

Mi Yeon Lee,Ki Hyun Ryu,Jin Sung Hong,Yeon Sook Song 한국육종학회 2009 한국육종학회 학술발표회 발표요지 Vol.41 No.1

Effects of Dioxin Exposed in Human by Using Radioactive cDNA Microarray

Ryu, Yeon-Mi,Kim, Ki-Nam,Kim, Hye-Won,Sohn, Sung-Hwa,Lee, Seung-Ho,Kim, Yu-Ri,Seo, Sang-Hui,Lee, Seung-Min,Lee, Eun-Il,Kim, Meyoung-Kon The Korean Society of Toxicogenomics and Toxicopro 2006 Molecular & cellular toxicology Vol.2 No.1

2, 3, 7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) are well known as the most toxic environmental compound in these days. Many researches are reported that dioxin produces multiple toxic effects, such as endocrine toxicity, reproductive toxicity, immunotoxicity and cancer. In this study, we carried to discover novel evidence for previously unknown gene expression patterns in human exposed to dioxin by using radioactive cDNA microarray. 548 workers who were divided into experimental and control groups according to their urinary Naphthol levels were enrolled in our study. Blood mRNA in human was isolated, and the gene expression profiles were analyzed by cDNA microarray. Gene expression analysis identified 52 genes which exhibited a significant change. In our study, most notably, genes involved in cell cycle, cell proliferation, signal transduction and apoptosis in human exposed to dioxin, such as CCND3, TSHR, and EFRN5, were up-regulated. In the current study, we observed gene expression of people that are exposed to dioxin using radioactive cDNA microarray. Through these results, we suggest when objects are exposed to toxic compounds, such as dioxin, the radioactive cDNA microarray may be using in sensitively detecting of cancerous change.

Inhibition of 15-Hydroxyprostaglandin Dehydrogenase by <i>Helicobacter pylori</i> in Human Gastric Carcinogenesis

Ryu, Yeon-Mi,Myung, Seung-Jae,Park, Young Soo,Yang, Dong-Hoon,Song, Ho June,Jeong, Jin-Yong,Lee, Sun Mi,Song, Miyeoun,Kim, Do Hoon,Lee, Hyo-Jeong,Park, Soo-Kyung,Fink, Stephen P.,Markowitz, Sandy D.,J American Association for Cancer Research 2013 Cancer prevention research Vol.6 No.4

<P><I>Helicobacter pylori</I> (<I>H. pylori</I>) infection induces a chronic inflammatory response, which promotes gastric carcinogenesis. 15-Hydroxyprostaglandin dehydrogenase (15-PGDH) plays a key role as a tumor suppressor in gastrointestinal cancers. The aim of this study was to elucidate the role of 15-PGDH in gastric carcinogenesis associated with <I>H. pylori</I>. 15-PGDH expression in gastric biopsies from <I>H. pylori</I>–infected (<I>n</I> = 25) and noninfected (<I>n</I> = 15) subjects was analyzed by quantitative real-time PCR, Western blot analysis, and immunohistochemistry. 15-PGDH DNA methylation was evaluated by methylation-specific PCR and pyrosequencing. The expression of 15-PGDH, Snail, extracellular signal–regulated kinase (ERK)1/2, TLR4, and MyD88 in response to <I>H. pylori</I> infection was assessed by immunoblot analysis. Compared with negative specimens, <I>H. pylori</I>–positive specimens had 2-fold lower 15-PGDH mRNA levels and significantly less 15-PGDH protein. In four <I>H. pylori–</I>infected subjects with longitudinal follow-up, the suppression of 15-PGDH expression was reversed by <I>H. pylori</I> eradication therapy. In parallel with suppressing 15-PGDH expression, <I>H. pylori</I> infection activated expression of TLR4 and MyD88 expression, increased levels of phospho-ERK1/2, and increased expression of EGF receptor (EGFR)-Snail. Inhibition of Snail and MyD88 reversed suppression of 15-PGDH expression, and siMyD88 reduced phosphorylated ERK1/2. Similarly, treatment with an ERK1/2 and EGFR inhibitor also restored 15-PGDH expression. <I>H. pylori</I> appeared to promote gastric carcinogenesis by suppressing15-PGDH. This process is mediated by the TLR4/MyD88 pathway via ERK1/2 or EGFR-Snail transcriptional regulation. 15-PGDH may be a useful marker and a potential therapeutic target in <I>H. pylori</I>–induced gastric carcinogenesis. <I>Cancer Prev Res; 6(4); 349–59. ©2013 AACR.</I></P>