鹽化物 含有量에 따른 鐵筋腐食 및 콘크리트 强度特性에 관한 實驗的 硏究

김정섭,강연구,유덕룡,박광수 朝鮮大學校 建設技術硏究所 1999 建設技術硏究 Vol.19 No.2

As reinforced concrete buildings have been large, high-storied and high perfomance supply of river sand and gravel is insufficient and sex sand and crushed gravels which have the problem in internal force and durability are used as substitute aggregates. The problems caused by the use of sea sand lower the durability of reinforced concrete building according t o the content of chloride and shellfishes and cause the problem of corrosion and neutralization of reinforcing rod. Therefore, this study analyzes the degree of corrosion and neutralization of reinforcing rod which are the causes of lowering durability of reinforced concrete buildings with the variable of chloride content through the experiment and obtains the following results. 1. As a result of experimenting river sand and sea sand by comparison, the corrosion can be found at reinforcing rod without using rust proof paint regardless of the covering depth from 60 days of age and especially, the extensive corrosion is occurred at the damaged reinforcing rod among the same rods. 2. As a result of neutralization experiment with river sand and sea sand, there is no response in neturalization till 60 days of age. 3. As a result of strength and non-destructive strength test with river sand and sea sand, it is found that the value of strength is increased more at the test specimen using sea sand than river sand and while the specimen using river sand shows increasing value of strength continuously based on 28 days of age, the specimen using sea sand shows the decrease in strengh as it has more chloride contents. It is thought that evaluation experiment and method of durability and security and countermeasure of durability according to age on the basis of the basic materials of this study should be conducted as future research task.

강릉시 사망원인 분석

김상아,곽연희,박웅섭,송재석,이상욱,박덕영,강명근 關東大學校 醫科大學 醫科學硏究所 2002 關東醫大學術誌 Vol.6 No.1

This study was conducted to use for the Community Health Care Plan through analyzing the specific cause of death in Gangneung. The study subject were death in Gangneung that happened from January 1, to December 31 in 2000, and that were enrolled as the citizen of Gangneung. The causes of death were classified according to the 56 selected list for ranking of causes of death in Korean National Statistical Office in order to compare the data of nation. We also estimated Years of Potential Life Lost in order to evaluate the burden of disease in Gangneung.

씨름선수에서 체중 감량과 회복기의 Leptin과 PAI-1 변화

김용운,도경오,권태동,박덕일,장응찬,박소영,김종연,이석강 대한스포츠의학회 2000 대한스포츠의학회지 Vol.18 No.2

Obesity which is defined as accumulation of excess body fat, is central factor of insulin resistance syndrome. Recently, it is revealed tat adipose tissue is not simply an energy storage organ but it also secretes a variety of molecules which affect the metabolism of the whole body, those are leptin and plasminogen activator inhibitor-1(PAI-1). Therefore, leptin and PAI-1 are increased in the obese state. Leptin regulates energy homeostasis and satiety and PAI-1 regulates fibrinolytic system. For these reasons, elevated levels of leptin and PAI-1 are considered as link factors between obesity and insulin resistance syndrome. However, the exact regulating mechanism for serum levels of leptin and PAI-1 is not fully understood yet. In this study, to evaluate the regulating mechanisms of serum levels of leptin and PAI-1 according to the weight changes, we measured leptin, PAI-1, physical, metabolic, and endocrine parameters during 10 days of weight reduction and 10 days of regain period in 7 young athletes. The mean body weight change was -4.7 kg(5.0%) in the weight reduction period and -2.4 kg(2.5%) in the weight regain period compared to baseline value. Baseline level of leptin in athletes was 1.7±0.66 ng/ml, which was significantly correlated with body weight, BMI, percent body fat, body fat mass, triglyceride, insulin, and PAI-1. Baseline level of PAI-1 in athletes was 16.6±5.26 ng/ml, which was significantly correlated with body weight, BMI, triglyceride, insulin, and leptin. Leptin was decreased to 0.7±0.39(44% of the basaline value) in the weight reduction period, and increased to 1.9±0.64(119% of the baseline value) in the regain period. PAI-1 was decreased to 7.4±2.72(44% of the basaline value) in the weight reduction period, and increased to 22.8±7.33(138% of the baseline value) in the regain period. The changes of leptin during weight reduction period were significantly correlated with the changes of insulin(r=0.890, P<0.01) and triglycerides(r=0.874, P<0.01). The changes of PAI-1 during weight reduction period were significantly correlated with the changes of FFA(r=0.889, P<0.01) and triglycerides(r=0.869, P<0.05). The changes of both leptin and AAI-1 during weight regain period were significantly correlated with the changes of insulin(r=0.755 and 0.849, P<0.05, respectively). In summary, these results suggest that serum levels of leptin and PAI-1 were affected by weight cycling, the percentages of change were more greater than that of weight change, and rebound phenomena were occurred during weight regain period.

정신분열병 환자의 병식과 임상양상의 관련성에 관한 연구

주연호,김수동,송진우,박성덕,오석배 용인정신의학연구소 1998 용인정신의학보 Vol.5 No.2

<i>Epilithonimonas ginsengisoli</i> sp. nov., isolated from soil of a ginseng field

Hoang, Van-An,Kim, Yeon-Ju,Ponnuraj, Shree Priya,Nguyen, Ngoc-Lan,Hwang, Kyu-Hyon,Yang, Deok-Chun International Union of Microbiological Societies 2015 International journal of systematic and evolutiona Vol.65 No.1

<P>A novel Gram-staining-negative, rod-shaped bacterium, designated DCY78<SUP>T</SUP>, was isolated from soil of a ginseng field in Yeon-cheon province (38° 04′ 00″ N 126° 57′ 00″ E), Republic of Korea. The phylogenetic analysis based on 16S rRNA gene sequences showed that strain DCY78<SUP>T</SUP> belonged to the genus <I>Epilithonimonas</I> and was most closely related to <I>Epilithonimonas lactis</I> DSM 19921<SUP>T</SUP> (98.5 % sequence similarity) and <I>Epilithonimonas tenax</I> DSM 16811<SUP>T</SUP> (97.8 %). Growth occurred at 10–30 °C with an optimum temperature of 28 °C. The pH range for growth was pH 5.5–8.0. The major polar lipids were found to be phosphatidylethanolamine three unidentified amino lipids and one unidentified polar lipid. The only predominant quinone was MK-6. The major polyamines were <I>sym</I>-homospermidine and spermidine. The major fatty acids were summed feature 3 (comprising C<SUB>16 : 1</SUB>ω6<I>c</I> and/or C<SUB>16 : 1</SUB>ω7<I>c</I>), iso-C<SUB>15 : 0</SUB> and iso-C<SUB>17 : 0</SUB> 3-OH. The DNA G+C content was 37.9 mol%. On the basis of the phenotypic and genotypic analysis, the isolate is classified as representative of a novel species in the genus <I>Epilithonimonas</I>, for which the name <I>Epilithonimonas</I> <I>ginsengisoli</I> is proposed. The type strain is DCY78<SUP>T</SUP> ( = KCTC 32174<SUP>T</SUP> = JCM 19896<SUP>T</SUP>).</P>

비감속 252Cf중성자선원에 대한 비등방성교정인자 및 선량당량환산인자

장시영,정덕연,윤석철,김종수 대한방사선 방어학회 1993 방사선방어학회지 Vol.18 No.2

중성자 측정장비 교정을 위한 표준중성자장을 제작하기 위하여 순수멕스월분포(kt=1.42MeV)로부터 ??Cf 자발핵분열 중성자선원의 밀봉이 교정인자에 미치는 영향을 고찰하였다. SR-Cf-100과 SR-Cf-1273 밀봉모형을 실제 제작조건으로 하여 MCNP 코드를 사용하여 몬테카를로 모의를 수행하여, 비등방성교정인자와 선속밀도-대-선량당량 환산인자를 산정하였고, 다른 연구결과와 비교하였다. 결과로서, Fi(θ=90˚)는 1.061(통계오차 : ±0.2%), H/??는 333.9[pSv·㎠] (통계오차 : ±0.5%)인 것으로 산정되었다. 이 환산인자(H/??)의 값은 ISO 8529의 권고보다 1.8%가 작은 것인데, 이것은 한국원자력연구소의 비감속 ??Cf중성자선원의 스펙트럼이 ISO의 것보다 약간 더 연화하다는 물리적 의미를 갖는다. Form the pure Maxwellian distribution(kT= 1.42MeV), the effects upon calibration factors of encapsulating a Cf spontaneous fission neutron source were invdwtigated to establish a standark neutron field in the Secondary Standark Kosimetry laboratory at Korea Atomic Inergy Research Institute(KAERI). A Monte Carlo code MCNP was used in simulating the encapsulation SR-Cf-100 and SR-Cf-1273 to be real conditions. The anisotropy(FI) and fluence-to-dose equivalents conversion factors(H/Φ) were evaluated and compared with other results. As the results, the FI was determined to be 1.061 atθ=90˚ with ±0.2% statistical error and the (H/Φ) was evaluated to be 333.9 [pSv·㎠] with ±0.5% statistical error, which is lower by 1.8% than that recommended by the ISO 8529. This means physically that the neutron spectrum of the unmoderated Cf source in KAERI is a little more softened than that by the ISO.

운동부하 흰쥐에서 포도당 증합체가 심근 당원에 미치는 영향

이석강,조성현,김용운,박덕일,김종연,장용찬 대한스포츠의학회 1994 대한스포츠의학회지 Vol.12 No.1

운동부하전 섭취한 탄수화물이 운동흰쥐의 심근 및 골격근이 당원량에 미치는 영향을 측정하여 심근과 골격근의 대사적 차이점의 일단을 연구한 본 논문의 결과는 다음과 같다. 심근과 골격근 당원량(mg/ g wet tissue, 이하 단위 동일)은 정상군에서 심근 2.62±0.51로서 골격근의 3.37±0.58보다 낮았다(p<0.01). 심근 당원량은 정상군이 2.62±0.51이었다. 운동 30분에서 대조군은 정상군의 63%수준으로 감소하였으며(p<0.01), 탄수화물섭취군은 정상군의 86 및 90%수준으로 감소하였으나 통계적으로 유의한 차이는 없었다. 탄수화물 섭취군의 당원량은 대조군의 142 및 137%정도로 양군 모두 대조군보다 유의하게(p<0.01) 높았다. 운동 60분에는 대조군은 운동30분의 78%(정상군의 49%)수준으로 감소하였으며(p<0.05) 탄수화물섭취군은 포도당중합체 및 포도당섭취군에서 각각 운동 30분에 비하여 72(p<0.01, 정상군의 62%), 81%정도(p<0.05, 정상군의 73%)로 감소하였다. 포도당 섭취군의 당원량은 대조군의 147% 정도로 대조군보다 유의하게(p<0.01) 높았다. 운동 120분에서 대조군은 운동 60분에 비하여 63%(정상군의 33%) 수준으로 감소하였으며 (p<0.01) 포도당섭취군은 운동 60분의 69%(정상군의 50%)수준으로 유의하게 감소하였으나, 포도당 중합체 섭취군은 차이가 없었다. 탄수화물 섭취군의 당원량은 포도당 중합체 및 포도당섭취군에서 각각 대조군의 202 및 162% 정도로 양군 모두 대조군보다 유의하게(p<0.01)높았다. 골격근 당원량은 정상군이 3.37±0.58 이었다. 운동 30분에서 대조군은 정상군의 69% 수준으로 감소하였으며(p<0.01) 탄수화물섭취군은 포도당 중합체 및 포도당섭취군에서 각각 정상군의 85 및 88% 수준으로 감소하였으나 통계적으로 유의한 차이는 없었다. 탄수화물 섭취군의 당원량은 포도당 중합체 및 포도당섭취군에서 각각 대조군의 125 및 129% 정도로 양군 모두 대조군보다 유의하게(p<0.05) 높았다. 운동 60분에는 대조군은 운동 30분의 77%(정상군의 53%) 수준으로 감소하였으며(p<0.05)탄수화물섭취군은 포도당중합체 및 포도당섭취군에서 각각 30분에 비하여 93(정상군의 80%), 89(정상군의 78%) %정도로 감소하였으나 통계적으로 유의하지는 않았다. 포도당중합체 및 포도당 섭취군의 당원량은 각각 대조군의 152 및 149% 정도로 대조군보다 유의하게 (p<0.001) 많았다. 운동 120분에서 대조군은 운동 60분에 비하여 50%(정상군의 26%) 수준으로 감소하였으며(p<0.001) 포도당 섭취군은 운동 60분의 75%(정상군의 58%)수준으로 유의하게(p<0.05) 감소하였으나 포도당 중합체 섭취군은 대조군의 84%(정상군의 67%)정도로 감소하는 경향을 보였다. 탄수화물 섭취군의 당원량은 포도당 중합체 및 포도당섭취군에서 각각 대조군우ㅢ 255 및 221% 정도로 양군 모두 대조군보다 유의하게(p<0.001) 높았다. 이상의 결과로 미루어 보아 심근과 골격근 간의 생리, 생화학적 특성의 차이에도 불구하고 탄수화물의 섭취후 중등도 정도의 달리기 운동시 근 당원의 함량에 미치는 영향은 정도의 차이는 있으나 같은 경향을 나타내었으며, 골격근에서 심근보다 더 많은 근 당원 절감효과를 나타내었다. 또한 운동전 탄수화물의 섭취시 이러한 근 당원 절감 효과로 장시간의 운동시 심근 및 골격근 당원의 고갈 지연으로 운동수행능력의 증가가 기대되며, 특히 포도당 보다는 포도당 중합체의 섭취시 효과가 더 크리라고 사료된다. The purpose of this study was to investigate the effect of glucose and glucose plymer ingestion on the concentration of the cardiac muscle glycogen at 30, 60 and 12 minutes of the treadmill running in rats. Rats were randomly assinged to normal, control, and carbohydrate groups. Carbohydrate group was divided into glucose, and glucose polymer ingested rats. The experiment was carried out after overnight fasting. Rats were administrated either water (control) of carbohydrates of formulated glucose(6%), and glucose polymer(6%) via polyethylene tube to the stomaach before treadmill run. Exercise was loaded by a treadmill run at the speed of I ㎞/hr for 30, 60, and 120 minutes. The results of experiment were as follows: Glycogen content of the cardiac muscle was lower than that of the skeletal muscle (plantaris) in normal rats. Glycogen content of the cardiac muscle was decreased in proportion to the exercise time compared to normal in control and carbobydrates ingested rats. It decreased in control, glucose, and glucose polymer compared to normal rats in decreasing order at 120 minutes treadmill running (% change of glycogen content of control, glucose, and glucose polymer compared to normal rats were 33, 50, and 63% in the cardiac muscle at 120 minutes of treadmill running respectively). Glycogen content of the skeletal muscle was decreased in proportion to the exercise time compared to normal in control and corbohydrates ingested rats. It decreased in control, glucose, and glucose polymer compared to normal rats in ecreasing order 120 minutes treadmill running(% change of glycogen content of control, glucose, and glucose polymer compared to normal were 26, 58, and 67% in the cardiac muscle at 120 minutes of treadmill running respectively). Change of the glycogen content of the cardiac and the skeletal muscle during treadmill running after glucose and glucose polymer ingestion showed that both muscles had tendency to decrease in proportion to exercise time similarly in control and carbohydrates ingested rats. Decreasing rate of glycogen content of cardiac and skeletal muscles during treadmill running compared to normal in carbohydrates ingested rats was lower than that of control. From these results, it is suggested glycogen content of cardiac and skeletal muscles had tendency to decrease in proportion to exercise time similarly in control and carbohydrate ingested rats. Glycogen content of cardiac and skeletal muscles in carbohydrate singested rats less decreased than that of control during treadmill running compared to normal. Glucose polymer of the carbohydrates ingested rats in considered as the most effective for glycogen sparing according to exercise time in both muscles. Therefore, intake of carbohydrate, especially glucose polymer, before exercise may be increase performance of the prolonged moderate exercise.

형질전환 제초제저항성 벼 밀양 204호의 농업적 특성

정응기,이기환,원용재,박향미,전남수,최준호,구연충,한창덕,은무영,김태산,남민희 Plant molecular biology and biotechnology research 2005 Plant molecular biology and biotechnology research Vol.2005 No.

This study was conducted to investigated the major characteristics of genetically modified rice of "Milyang 204" originated from Dongjinbyeo compared to a non-transgenic rice varieties Dongjinbyeo and Junambyeo. Basta resistant transgenic rice lines carrying bar gene produced by the Yeongnam Agricultural Research Institute were evaluated for their agronomic characters. The transgenic Japonica rice of "Milyang 204" showed inferior phenotypic traits compared to a non-transgenic rice variety Dongjinbyeo and Junambyeo. On the basis of UPOV (Union Internationale Pour la Protaection des Obtentions Vegetables) and NSMO(National Seed Management Office) the transgenic "Milyang 204" showed difference in some traits out of some agronomic traits, such as leaf color, angle of flag leaf, number of spikelets, culm length, white core and white belly compared to the nontransgenic varieties rice.

동일한 국제예후지표(International Prognostic Index)를 나타내는 미만성 대형 B-세포 림프종에서 Bcl-2와 p16의 임상적 중요성

박상은,박수진,곽승근,박남숙,천재민,윤환중,조덕연,김삼용,김진만 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

In Korea, malignant lymphoma is a common cancer, comprising about 2.7% of all malignant neoplasm. Diffuse large B cell lymphoma is the most common lymphoma, representing about 50% of all Non-Hodgkin's lymphoma. Diffuse large B-cell lymphoma is usually considered as heterogeneous group of neoplasms rather than a single clinicopathological entity. Clinical prognostic systems, including the International Prognostic Index (IPI), although useful to assess overall prognosis, embrace patients with heterogeneous prognoses. But International Prognostic Index scoring system is not sufficiently predict the prognosis. It is likely that the prognostic assessment of patients with diffuse large B-cell lymphomamight be improved by using biological features. Bcl-2 protein and p16 protein expression is recognized as useful biologic markers predicting the prognosis of patients with diffuse large B-cell lymphoma. To determine the clinical significance and prognostic value of bcl-2 and p16 proteins expression patterns, we studied 18 patients with de novo DLBL, whose archival pathology specimen were available for immunohistochemistry studies, atChungnam National University Hospital from September 1992 to December 2000. Archival specimens from each patient were immunostained with respective antibodies for bcl-2, p16. The results are as follows; 1) The median age was 54(rage : 37-69). There were 12 male patients(66.7%) and 6 female patients(33.3%) The 'B' symptom was abscentin all patients. The stages were as follows : Ⅰ, 2 patient(11.1%), Ⅱ, 10 patient(55.6%), Ⅲ, 4patient(22.2%) and Ⅳ, 2patient(11.1%). 3 patients(16.8%) had the elevated LDH level, 14 patients(77.8%) had the normal LDH level and 1 patients(5.6%) was not identified the LDH level. 2 patients(11.1%) had the bulky disease and 16 patients(88.7%) had no bulky diease. The distribution of ECOG status were O, 2 patients(11.1%c), 1, 14patients(77.8%) and 2, 2patients(11.1%). 2) Theimmunohistochemistry results are as follows bcl-2:+,10 patients(55.6%), bcl-2:-, 8patinets(44.4%), p16:+,3 patients(16.7%), p16:-, 15patients(83.3%) 3) After a median follow UP durations of 67 months, the median survival time was 57 months with a rage of 7-100+ months. 5-years overall survival rates was 44% by Kaplan-Meier method. 4) Reduced overall survival was demonstrated in the patients who expressed bcl-2 protein(P=0.0174). 5-year overall survivial rate was 12%(bcl-2 expression) versus 88%(no bcl-2 expression) 5) Among diffuse large B-cell lymphoma patients with IPI score 0-1, reduced overall survival was demonstrated with bcl-2 expression(P=0.023). 5-year overall survival rate was 18%(bcl-2 expression group) versus 100%(no bcl-2 expressiongroup) 6) Median survival durtation of diffuse large B-cell lymphoma patients negative for p16 expression was 57 months whereas p16 postive patients' median survival duration was not reached(P=0.4478). In diffuse large B-cell lymphoma patients with identical IPI scores, bcl-2 expression had additional prognostic value.

Korean Youth with Comorbid Allergic Disease and Obesity Show Heightened Psychological Distress

Kim, Soo Yeon,Choi, Sun Ha,Kim, Jong Deok,Sol, In Suk,Kim, Min Jung,Kim, Yoon Hee,Jung, Young-Chul,Sohn, Myung Hyun,Kim, Kyung Won Elsevier 2019 The Journal of pediatrics Vol.206 No.-

<P><B>Objective</B></P> <P>To explore psychological distress in Korean adolescents having allergic disease comorbid with obesity.</P> <P><B>Study design</B></P> <P>A total of 703 869 adolescents who completed the Korean Youth Risk Behavior Web-based Survey between 2007 and 2016 were analyzed. Participants were divided into 4 groups—healthy control, allergic disease only, obesity only, and comorbidity of allergic disease and obesity—and compared them to determine whether they showed differences in mental health.</P> <P><B>Results</B></P> <P>Adolescents with both atopic dermatitis and obesity had significantly greater odds of experiencing unhappiness (OR, 1.17), stress (OR, 1.32), and suicidal ideation (OR, 1.25) than those without both conditions. The same was true of adolescents with obesity and allergic rhinitis (OR, 1.21, 1.37, and 1.27, respectively) or bronchial asthma (OR, 1.37, 1.39, and 1.37). The comorbidity groups also showed significantly greater odds of stress and suicidal ideation than the allergic disease-only (atopic dermatitis with obesity, 1.21 and 1.15, respectively; allergic rhinitis with obesity, 1.11 and 1.09; bronchial asthma with obesity, 1.17 and 1.14) and obesity-only groups (atopic dermatitis with obesity, 1.13 and 1.09; allergic rhinitis with obesity, 1.18 and 1.10; bronchial asthma with obesity, 1.18 and 1.21).</P> <P><B>Conclusions</B></P> <P>Allergic disease and obesity negatively and additively influence mental health in adolescents.</P>