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      • 호산구성 기관지염의 임상적 특징

        김용현,윤여일,임건일,박상준,주재학,김용훈,박춘식 순천향의학연구소 2001 Journal of Soonchunhyang Medical Science Vol.7 No.2

        Background: Eosinophilic inflammation of airway is usually associated with airway hyperresponsiveness in bronchial asthma. However, there is a small group of patients who has the eosinophilic inflammation in the bronchial tree with normal spirometry and no evidence of airway hyperresponsiveness, which was named eosinophilic bronchitis. The objectives of this study are 1) to investigate the incidence of eosinophilic bronchitis in the chronic cough syndrome and 2) to evaluate the clinical features and course of eosinophilic bronchitis. Methods : We evaluated 92 patients who had persistent cough for 3 weeks or longer. In addition to usual diagnostic protocol, we performed differential cell count of sputum. Eosinophilic bronchitis was diagnosed when the patient had normal spirometic values, normal peak expiratory flow variability, no airway hyperresponsiveness, and sputum eosinophilia(>3%). Result : The causes of choronic cough were post-nasal drip in 33%, cough variant asthma in 16%, bronchitis in 15%, and eosinophilic bronchitis in 12% of the study subjects. Initial eosinophil percentage in sputum of patience with eosinophilic bronchitis was 26.8±6.1% (3.8-63.7%). Treatment with inhaled steroid is related with a subjective improvement of cough severity and a significant decrease of sputum eosinophil percentage (from 29.1±8.3% to 7.4±3.3%)/ During the follow up period of over ? months, recurrence of cough of was associated with reappearance of sputum eosinophilia. Conclusion : Eosinophilic bronchitis is one of the important causes of chronic cough. Assessment of airway inflammation by sputum examination is important in investigating the cause of chronic cough. Cough in eosinophilic bronchitis are effectively controlled by inhaled corticosteroid, but it recurs frequently over a long term period of follow-up(Korean J Med 60:77-84, 2001)

      • 당뇨병 환자에서 발생된 고열을 동반한 베체트병 1예

        김여주,오정은,김상진 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        Behcet's disease is a multisystem vascular inflammatory disease of unknown origin. It is characterized by recurrent aphthous stomatitis, uveitits, genital ulcer and skin lesions. All these common manifestations are self-limiting except for the ocular attack. Repeated attacks of uveitis can cause blindness. Involvement of the gastrointestinal tract, central nervous system and large vessels is less frequent, although it can be life-threatening. There is no pathognomonic laboratory test but there are clinical criteria to assist in establishing the diagnosis. One of the clinical features of Behcet's disease is low-grade fever, which usually accompanies the inflammatory manifestations of the disease. But high fever is rare. Therefore, we reported a case of Behcet's disease presented by high fever in a patient with diabetes mellitus.

      • 특발성 혈소판감소성 자반증 환자에서 발생된 그레이브스병 1예

        김여주,이규택,김상진,김휘준 순천향의학연구소 2004 Journal of Soonchunhyang Medical Science Vol.10 No.2

        The autoimmune nature of idiopathic thrombocytopenic purpura(ITP) and Graves' disease has been well established. In both disease, circulating immunoglobulins are believed to be involved in the pathogenesis and transplacental transfer of both disease is the ultimate proof of the importance of the humoral mechanism involved. Because of the tendency of autoimmune disease to cluster in the same individual or members of the same family, simultaneous incidence of ITP and Graves' disease is to be expected. However, in clinical practice, it has been described only rare. Therefore, we report here the case of a patient suffering sequentially from ITP and Geaves' disease with the literature.

      • 필라델피아 염색체 양성 급성골수성백혈병에서 Imatinib Mesylate로 분자학적 관해를 유도한 후 성공적인 자가 말초혈액 조혈모세포이식이 시행되었던 1예

        김여경,이제중,이병환,변정래,조덕,이일권,정익주,양동욱,김형준 대한조혈모세포이식학회 2003 대한조혈모세포이식학회지 Vol.8 No.1

        저자들은 필라델피아 염색체 양성 급성골수성백혈병 환자에서 복합항암화학요법으로 혈액학적 완전관해를 유도하고, imatinib mesylate를 이용하여 분자학적 관해를 유도한 후, 성공적으로 자가 말초혈액조혈모세포이식을 시행하였던 1예를 경험하였기에 이를 보고하는 바이다. Philadelphia chromosome (Ph¹)-positive acute myeloid leukemia (AML) is very rare disease, comprising 3~4% of the AML, and is a clinically distinct entity with poor clinical outcome with conventional chemotherapy. We report a case of Ph¹-positive AML who underwent successful autologous peripheral blood stem cell transplantation after achieving a molecular remission with imatinib mesylate.

      • KCI등재후보

        복합문화공간의 색채특성에 관한 연구 : 문화예술공간의 공간별 색채특성을 중심으로

        여화선,서주환,김도훈 경희대학교 부설 디자인연구원 2008 예술· 디자인학연구 Vol.11 No.1

        Cultural complex is needed and recognized as effective means to deliver more advanced living environment in quality and enable modern man to use time most diffidently. This study not only has investgation of the color is applied to the impact of space and the concept of a complex cultural space but also has analysis of the color characteristics of each is a complex cultural space. Also, our purpose is understanding of problem for color analysis result. The place of investgation was 5 sites. Sites are Kring, Space*C in Gangnam-gu and Sangsang-madang, Loop, Xi-Gallery in Mapo-gu. The scope of our investgation was limited in a cultural-art space rather than commercial space. The result of this study can be summarized as follows : The color of complex cultural space is not much different from the color of a common space. But The development of complex cultural space and increase the satisfaction of users is important to plan the appropriate color. Also, the appropriate color plan will offer to people high noble and secluded place.

      • 화상 신호를 이용한 금속표면의 미소 결함 측정에 관한 연구

        이주상,윤여권,김희남 明知大學校 産業技術硏究所 1993 産業技術硏究所論文集 Vol.12 No.-

        This paper reports a method of measuring surface scratch using microscope and CCD. Included are both the theory of the technique and experimental verification. The range of surface scratch which can be accurately measured by this method is also reported. The nature of this method it is anticipated that the effective automatic testing and sorting can be possible for precision machining work.

      • KCI등재후보

        복합문화공간의 색채계획 : 수원시 영통구 상업지구를 중심으로

        서주환,여화선,최선주,박선영,김옥경,승지현,김홍균 경희대학교 부설 디자인연구원 2007 예술· 디자인학연구 Vol.10 No.1

        The recognition on leisure living which have been enjoyed by prestige level from popular persons is now widely spreaded in modern capitalism society and change of the leisure living influenced very much to the society and Industry. The 5 day work per week system expanded to the school and contemporary leisure living of the people is recognised as one culture with various contents. This change of leisure living made a recognition on the need for a space for leisure culture contents, which related to a creation of Complex-culture facility to contain various type of multiple leisure culture. The Complex-culture facility is mainly focused on the entertainment space with increased leisure living, which is consist of important element of the Complex-culture facility as performance space, exhibition, sports and shopping space to construct performance hall, theater, exhibition room, sports center, shopping mall, leisure space and plaza. This study, therefore, will Investigate on the function and value of color, and review on the cases of Complex-cultural facility and then choose a space of cultural element lack. It will recompose in Complex-cultural facility.

      • 저강도 초음파 및 레이저를 이용한 장관골 불유합의 치료

        전인호,오창욱,김성중,경희수,박일형,박병철,인주철,여준영 대한골절학회 2003 대한골절학회지 Vol.16 No.2

        목 적: 저강도 초음파는 인체 및 동물 실험에서 골조직에 낮은 미세한 물리적 압력을 가하여 골절의 치유에 유리한 영향을 주고, 레이저 (LASER)는 심부 조직에 혈류를 증가시키고, 세포 내 잠재된 에너지를 증가시키는 것으로 알려져 있다. 이에 저자들은 임상적으로 확진된 장관골 붕류합의 치료에 있어 펄스형 저강도 초음파와 레이저를 적용하고 그 효용성을 알아보고자 하였다. 대상 및 방법: 초음파/레이저의 치료 효과를 비교하기 위하여 장관골 불유합으로 확진된 16예 중 8예는 연구군으로 골이식술 후 저강도 초음파와 레이저 치료를 추가하였고 대조군 8예에 대해선 일반적인 골이식술만 시행하여 조사하였다. 남자가 11예, 여자가 5예, 평균 연령은 41.7세 (19~62세)였고, 불유합 부위는 대퇴골이 10예, 경골이 6예였다. 첫 수상으로 인한 골절 후 초음파/레이저 치료까지 시간(골절 연력)은 평균 502일이었다. 결 과: 8예의 연구군에서는 완전 골유합이 6예에서 이루어졌으며 유합까지의 시간은 평균 141일 (101~202일)로 나타난 반면, 8례ㅢ 대조군에서는 5예에서 골유합이 이루어졌고, 유합까지의 시간은 평균 240일 (183~283일)이었다. 결 론: 저강도 초음파/레이져 골절 치료기가 반복된 수술로 인한 난치성 장관골 불유합의 치료에 있어 골이식술과 함께 사용될 경우 긍정적인 효과가 있었고, 특히 최초 가골 형성에 있어 대조군에 비해 그 시간을 줄일 수 있었따. Purpose: Low-intensity, pulsed ultrasound (LIPUS) has demonstrated a stimulation and acceleration of the normal fracture-repair process in cellular bases as well in animal and human models. In this study, the adjunctive effect of LIPUS and LASER was investigated in established nonunion of the long bones. Materials and Methods: Study group consisted of eight patients to whom conventional bone graft and adjunctive LIPUS and LASER was applied. On the other hands, eight patients in the control group underwent bone graft only. Eleven men and five women were included in this study and the average age of the patients was 41.7 years (range, 19~62 years). Six of the tibias and ten of the femurs met the criteria for established nonunion. The average fracture age, the post-fracture period before the start of LIPUS/LASER treatment, was 502 days. Results: Seven of the ten nonunions who were treated by LIPUS and LASER healed completely in an average treatment time of 141 days (range, 101~202 days) and otherwise, in control group, five of the eight nonunions healed completely, in 240 days (range 183~283 days). Conclusion: This clinical study showed a positive effect of LIPUS and LASER on the rate of osseous repair, especially accelerated time to initial callus cortical bridging compared to that of conventional treatment.

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