구순열과 구개열환자의 특성에 관한 분석

나후자,양은진,김선,김수일,김원식 충남대학교 의과대학 지역사회의학연구소 1997 충남의대잡지 Vol.24 No.2

The cleft lip and cleft palate has relatively high incidence among congenital anomalies. The etiological factors of these anomalies have been studied widely, but they are not yet understood perfectly. So, the authors reviewed and analyzed retrospectively 505 cases of cleft lip and cleft palate patients who were treated at the Chungnam Uiversity Hospital during the past 12 years from January 1985 to December 1996 for evaluation of etiological factors of cleft lip and palate, and the results were as follows : 1. The male was affected 1.6 times more frequently in cleft lip with palate, but the female was affected 1.8 time more frequently in cleft palate alone. 2. The incomplete cleft lip was 1.7 times higher than complete type and the ratio of left, right and bilateral was 2.1 : 1 : 0.3, and complete cleft lip with palate was 4 times higher than incomplete type and the ratio of left, right and bilateral was 1.2 : 1 : 0.9. 3. The incomplete cleft palate was 6.6 times higher than complete cleft palate. 4. There was positive family history in 11.8% of all the patients. 5. There was combined congenital anomalies with cleft lip and palate in 18.8% of all patients, and the most frequently involved anomaly was the ear anomaly. 6. U.R.I was the most frequently involved disease and herb medicine was the most frequently administered drug during the frist trimester. 7. In educational level of parents, senior high school was 66.5% of all.

여러 가지 식품첨가제에 의한 Algin 용액의 유동 특성

김나미,박명한,전병선,박채규,양재원 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.2

알긴을 액상제품에 이용하기 위하여 algin의 농도와 수용액의 pH, 온도 변화에 의한 algin의 유동특성과 산미제, 감미제, 기타 첨가물이 algin의 점성에 미치는 영향을 조사하였다. 알긴 용액은 회전속도가 동일할 때는 농도가 높을수록 점도가 증가하였고 0.4% 농도까지는 dilatant형, 0.5% 이상에서는 pseudoplastic형 유체의 특성을 나타냈다. 알긴 용액의 pH가 5.5일 때 점도가 가장 높았고 pH 5.5 이하에서는 산성일수록 점도가 낮아졌으며, pH 7.0 이상에서는 점도의 변화가 없었다. 온도가 낮을수록 점도가 높았고, 가열함에 따라 용해시간이 단축되었으며 80℃이상의 가열에 의하여 점도가 다소 낮아졌다. 산미제에 의해 알긴의 점도는 pH 의존적으로 pH 3.2∼3.3에서 점도가 가장 낮았고 pH 3.0 이하에서는 gel이 형성되었다. 감미제는 알긴 용액의 점도에 영향을 주지 않았다. 무기염류 중 NaCl과 KCl은 점도를 감소시켰으며 MgCl_2와 CaCl_2는 점도를 증가시켰고, FeCl_3 첨가는 점도 증가효과가 커서 0.1% 첨가에 의햐여 gel이 형성되었다. 아미노산 중 glutamic acid는 1.0% 첨가 시에 점도 감소효과가 있었으며 다른 아미노산은 변화를 나타내지 않았다. In order to obtain data for use of algin in drink making process, solution properties of algin have been investigated at various condition of algin concentration, temperature, pH and various food additives. At same revolution velosity, viscosities of algin were increased as algin concentration raised. Algin solution showed dilatant type flow in concentration of 0.25% to 0.4%, but pseudoplastic type flow in above 0.5%. A maximum viscosity of algin was observed at pH 5.5 ad its viscosities were also decreased as the temperature increased and heating at 80℃ above. Organic acids affected on the viscosity of algin with pH dependently, and gel formed in pH below 3.0. Sweetners have no effect to the viscosity of algin. However, addition of NaCl and KCl upto 1.0% decreased a little its viscosity and CaCl_2, MgCl_2 and FeCl_3 increased the viscosity of algin. Glutamic acid decreased the viscosity of algin.

다시마 추출액의 점성과 향미 개선을 위한 볶음처리 조건

김나미,박명한,전병선,박채규,양재원 한국식품영양학회 1999 韓國食品營養學會誌 Vol.12 No.5

다시마 추출액의 향미와 물성을 개선하기 위하여 볶음처리에 의한 품질변화를 조사하고 최적 볶음조건을 선정하였다. 추출액의 상징액율과 고형분수율 및 조단백질 수율은 볶음온도와 시간이 증가할수록 높아졌다. Algin의 함량은 볶음온도 175℃에서 가장 높았고,회분의 함량은 볶음온도가 증가할수록 많아졌다. 추출액의 점도는 볶음온도와 시간이 증가함에 따라 낮아졌으며 175℃, 10분 볶음처리할 때 점도 감소가 뚜렷하였다. 추출액 의 pH는 볶음온도 150℃까지는 다소 낮아지는 경향이었으며 175℃ 이상의 볶음처리 시 볶음온도와 시간이 증가함에 따라 다소 높아졌다. 볶음온도와 시간이 증가함에 따라 명도(L값)은 감소하였고, 적색도(a값)과 황색도(b값)은 증가하다가 a값은 200℃ 15분처리, b값은 175℃, 30분 처리 이후에서 각각 감소되기 시작하였다. 다시마 추출액의 냄새는 175℃에서 볶음처리하였을 때 고소한 냄새가 크게 증가하고 메스꺼운 냄새가 뚜렷하게 감소되어 전체적인 기호도가 가장 높았다. 구수한 맛과 해조맛은 175℃에서 고소한 맛이 증가되면서 메스꺼운 맛이 뚜렷하게 감소되었고 200℃ 이상에서는 탄맛이 많아져 전체적인 맛의 기호도는 175℃에서 가장 좋은 것으로 평가되었다. 이상의 결과를 종 합하여 볼 때 다시마를 175℃에서 10분간 볶음처리하는 것이 다시마 추출액에서 좋지 않은 향미를 개선하고 점성을 감소시키기에 적합하였다. Roasting conditions for improvement of viscosity and sensory properties of sea tangle extracts were investigated. The supernatant %, solid yield and crude protein yield were increased by increasing of roasting temperature and times. The highest contents of algin was obtained in roasting temperature of 175℃, ash contents were increased by roasting temperature increasing. Viscosities of sea tangle extract were significantly decreased by increasing of roasting temperature and time upto 175℃ and 10 mins more than further roasting conditions. The pH of sea tangle extracts slightly decreased from 5.94 to 5.83 in the roasting of 150℃, however, at temperature more than 175℃, its pH was increased by increasing of temperature and time. According to increase of roasting temperature and time, Lightness (L value) were significantly decreased and redness (a value) and yellowness (b value) reached the highest value in the roasting of 200℃, 15 min. or 175℃, 30 min. and after that, its value were decreased. The odor characteristics showed that sea tangle extract prepared by roasting of 175℃, 10 min. was significantly low in intensity of nauseous odor and high in intensity of roasted odor and acceptability. The taste characteristics showed that sea tangle extract prepared by roasting of 175℃, 10mins was slightly reduced in intensity of savory and seaweed taste but significantly low in intensity of nauseous taste and high in intensity of roasted taste and acceptability. Overall data suggested 175℃, 10 min. was the most effective roasting conditions for improvement of viscosity and sensory properties of sea tangle extract.

中學 科學敎育의 探究學習에 대한 評價問項 開發 (Ⅱ)

閔庚德,楊洪準,李善行,鄭遠佑,이병교,金裕漢,羅長薰 경북대학교 과학교육연구소 1985 科學敎育硏究誌 Vol.9 No.-

This study was accomplished to develope the evaluation items for inquiry learning in the 2nd grade Middle School Science for the consecutive study of the evaluation items for inquiry learning in the 1st grade Middle School Science(U-Hang Ki et al, 1984). In this study, paper and pencil test items and performance test items are made by analyzing the abilities of inquiry according to the contents and four basic experiments from each unit in the 2nd grade Middle school science. These evaluation items were applied to tke five classes of the 2nd grade of middle school to test their validity. It is desirable that performance test schuld be used for the evaluation for the abilities of inquiry which can not be evaluated by paper and pencil test. In the evaluation methods of performance test, tester evaluation, peer evaluation and self-evaluation can be applied to the science class in a multi-student class. In higher grade, however tester evaluation is more desirable than peer and self evaluation. It is found that peer evaluation and self-evaluation make possible the perfect study by feedback.

Prevalence and clinical features of pneumonia in patients with laboratory-confirmed pandemic influenza A H1N1 2009 infection in South Korea

Na, Shin,Kim, Mi-Na,Kim, Won Young,Kim, Won,Hong, Sang-Bum,Lim, Chae-Man,Koh, Younsuck,Kwon, Ji-Won,Hong, Soo-Jong,Lee, Sang-Oh,Choi, Sang-Ho,Kim, Yang Soo,Woo, Jun Hee,Kim, Sung-Han Informa Healthcare 2011 Scandinavian journal of infectious diseases Vol.43 No.1

<P>During the early stages of the pandemic influenza A H1N1 2009 (pH1N1) outbreak in South Korea, the government recommended antiviral therapy with laboratory confirmation in specialized hospitals. Hence we had a unique opportunity to test all patients suspected to have pH1N1, including those who initially presented with a mild illness, such as those who were not in at-risk groups and who had an uncomplicated illness. We therefore evaluated the proportion and clinical features of pneumonia in patients with laboratory-confirmed pH1N1. Of the 3253 patients who visited Asan Medical Center, Seoul, South Korea, between 24 August and 19 October 2009 for a suspected pH1N1 infection (temperature ≥37.5°C and at least 1 of the following symptoms: sore throat, cough, rhinorrhoea and nasal congestion), 553 (17%) were positive for pH1N1 by real-time reverse-transcriptase polymerase chain reaction. Chest radiographs were performed in 96 (17%) of the 553 patients. Of the 553 patients, 30 (5%; 95% confidence interval (CI) 4-8%) had pneumonia, including 26 (86%) with viral pneumonia and 4 (14%) with bacterial pneumonia. So, the proportion of pneumonia in patients with laboratory-confirmed pH1N1 was at least 5%. Multivariate analysis indicated that dyspnoea (odds ratio (OR) 57.8, <I>p</I> < 0.001), wheezing (OR 19.3, <I>p</I> = 0.02), vomiting (OR 18.5, <I>p</I> < 0.001) and diarrhoea (OR 11.0, <I>p</I> = 0.001) were independently associated with pneumonia. Antiviral therapy at >48 h after the onset of symptoms (OR 2.1, <I>p</I> = 0.09) tended to be more common in patients with pneumonia than in those without pneumonia.</P>

Geometric Transformation Invariant Fast Image Identifier

Won-Keun Yang,Ayoung Cho,In-su Won,Sang-Il Na,Weon-Geun Oh,Dong-Seok Jeong 한국멀티미디어학회 2008 한국멀티미디어학회 학술발표논문집 Vol.2008 No.2

Image identifier can be used in finding original images from the large database of geometrically transformed images. In this paper, geometric transformation invariant fast image identifier is introduced. Proposed identifier consists of three different features. Used features are color feature, texture feature by Modified Generalized Symmetry Transform and angular partitioning feature. Each feature is quantized adaptively to compose three-dimensional histogram. For fast matching, pre-screening with bit-stream is used. Experimental results show that the proposed image identifier has good performance under various geometric transformations. And because of its fast matching, the proposed image identifier is very useful in real environment.

Low iPTH serum Level is associated with arterial stiffness In hemodialysis patients

Se Won Oh,Sun Chul Kim,Jin Joo Cha,Hye Won Kim,Ha Na Yang,Myung Gyu Kim,Sang Kyung Jo,Won Yong Cho,Hyoung Kyu Kim 대한내과학회 2009 대한내과학회 추계학술대회 Vol.2009 No.-

모야모야병에서 편측 중뇌출혈로 발생한 양안 상방주시마비 1예

이양원 ( Yang Won Lee ) , 이수나 ( Su Na Lee ) 대한안과학회 2004 대한안과학회지 Vol.45 No.10

A Low Intact PTH Is Associated with Simple Vascular Calcifications in Hemodialysis Patients

( Se Won Oh ),( Sun Chul Kim ),( Jin Joo Cha ),( Hae Won Kim ),( Ha Na Yang ),( Myung Gyu Kim ),( Sang Kyung Jo ),( Won Yong Cho ),( Hyoung Kyu Kim ) 대한신장학회 2011 Kidney Research and Clinical Practice Vol.30 No.3

Purpose: Cardiovascular diseases are a common cause of mortality in patients with end stage renal disease and are associated with vascular calcification (VC) and arterial stiffness. In addition to high turnover bone disease, there is substantial evidence that low levels of serum intact PTH (iPTH) are associated with vascular calcium deposition. The objective was to evaluate the association of iPTH levels with VC, arterial stiffness, and to identify risk factors contributing to VCs and arterial stiffness. Methods: One hundred five hemodialysis (HD) patients were divided into three groups according to iPTH levels: A, <150 pg/mL; B, 150≤and≤400 pg/mL; and C, >400 pg/mL. The simple vascular calcification score (SVCS) was obtained by X-ray; the brachial ankle-pulse wave velocity (ba-PWV) and the serum fetuin-A level was mesured. Results: Patients in group A were older and had a higher SVCS, a prevalence of diabetes, and an increased arterial stiffness. Severe VCs (SVCS≥3) were associated with the low iPTH group (iPTH<150) /a higher CRP/a lower diastolic blood pressure (DBP)/diabetes/ increased arterial stiffness/older age and a lower serum fetuin-A level. The log [ba-PWV] had a positive correlation with age, systolic blood pressure (SBP)/DBP/PP/CRP/presence of diabetes and low iPTH and a negative correlation with serum albumin. Based on multivariate analysis, the low iPTH group and diabetes were identified as independent risk factors of severe VC and age/SBP/CRP and diabetes were risk factors for arterial stiffness. Conclusion: Low iPTH levels and/or diabetes had a greater risk of developing VCs and age/SBP/CRP/diabetes were associated with increased arterial stiffness in HD patients.

Clinical Science : Original Article ; Increased Prevalence of Chronic Kidney Disease in Subjects Undergoing Coronary Angiography

( Ha Na Yang ),( Hye Won Kim ),( Myung Gyu Kim ),( Sang Kyung Jo ),( Won Yong Cho ),( Hyoung Kyu Kim ) 대한신장학회 2010 Kidney Research and Clinical Practice Vol.29 No.3

Purpose: The prevalence of Chronic Kidney Disease (CKD) is increasing worldwide and was recently reported to be up to 13.7% in general population in Korea. The purpose of this study was to investigate the prevalence of CKD in subjects undergoing coronary angiography (CAG). Methods: Six hundred six subjects who underwent CAG in Korea University Anam Hospital during the time frame of 4 months were included and prevalence of CKD was estimated by using K/DOQI guideline with MDRD equation. Coronary artery disease was defined as one or more significant stenosis (50% or more) at CAG. Results: The prevalence of CKD was 36.4%. The proportion of hypertension and diabetes, the well- known risk factors of CKD were not different with general population. The prevalence of coronary artery disease was not different between two groups with or without CKD. Conclusion: The prevalence of CKD in subjects who undergo CAG is higher than that in general population (36.4% vs. 13.7%). It seems to be related with or other factors than hypertension and diabetes. Subsequently, using contrast media to this population might carry a higher risk of developing contrast induced acute kidney injury. More attention to assessing kidney function before CAG in this population is needed.