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Xue-Lian Zhao,Shang-Ying Hu,Qian Zhang,Li Dong,Rui-Mei Feng,Ross Han,Fang-Hui Zhao 대한부인종양학회 2017 Journal of Gynecologic Oncology Vol.28 No.4
Objective: To explore the genotype distribution of high-risk human papillomavirus (HR-HPV) and its attribution to different grades of cervical lesions in rural China, which will contribute to type-specific HPV screening tests and the development of new polyvalent HPV vaccines among the Chinese population. Methods: One thousand two hundred ninety-two subjects were followed based on the Shanxi Province Cervical Cancer Screening Study I (SPOCCS-I), and screened by HPV DNA testing (hybrid capture® 2 [HC2]), liquid-based cytology (LBC), and if necessary, directed or random colposcopy-guided quadrant biopsies. HPV genotyping with linear inverse probe hybridization (SPF10-PCR-LiPA) was performed in HC2 positive specimens. Attribution of specific HR-HPV type to different grades of cervical lesions was estimated using a fractional contribution approach. Results: After excluding incomplete data, 1,274 women were included in the final statistical analysis. Fifteen point two percent (194/1,274) of women were HR-HPV positive for any of 13 HR-HPV types (HPV16, 18, 31, 33, 35, 39, 45, 51, 52, 56, 58, 59, and 68) and the most common HR-HPV types were HPV16 (19.1%) and HPV52 (16.5%). The genotypes most frequently detected in HR-HPV-positive cervical intraepithelial neoplasia grade 1 (CIN1) were HPV52 (24.1%), HPV31 (20.7%), HPV16 (13.8%), HPV33 (13.8%), HPV39 (10.3%), and HPV56 (10.3%); in HR-HPV-positive cervical intraepithelial neoplasia grade 2 or worse (CIN2+): HPV16 (53.1%), HPV58 (15.6%), HPV33 (12.5%), HPV51 (9.4%), and HPV52 (6.3%). HPV52, 31, 16, 33, 39, and 56 together contributed to 89.7% of HR-HPV-positive CIN1, and HPV16, 33, 58, 51, and 52 together contributed to 87.5% of CIN2+. Conclusion: In summary, we found substantial differences in prevalence and attribution of CINs between different oncogenic HPV types in a rural Chinese population, especially for HPV16, 31, 33, 52, and 58. These differences may be relevant for both clinical management and the design of preventive strategies.
Zeng-ru Zhao,Xin Wang,Xue-feng Zhang,Qiang Ma,Yan-li Liu,Yong-feng Li,Fei Liu,Gao-feng Wang 한국자기학회 2017 Journal of Magnetics Vol.22 No.1
Mischmetal of Bayan Obo ore was utilized to prepare the high performance (Pr7.34Nd21.86)1-xMMxFe68.7Al0.1-Cu0.12Co0.88B ribbons using melt-spinning method. Phase composition and magnetic properties were investigated at room temperature. The ribbons mainly consist of R2Fe14B phase in isotropic nanostructure. Both coercivity and maximum energy product decrease with the increase of MM content. The magnetic parameters of the ribbons with MM = 20 % in mass are Br = 7.38 kGs, Hcj = 13.66 kOe, (BH)max = 11.81 MGOe. Henkel plots were applied to demonstrate the exchange coupling interaction between grains.
Analysis of SCARA Robot Controller
Feng Cao,Xue-Heng Tao,Xin Zhao,Jin-Shi Lu 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-
The robot controller is one of the key parts in the robot. It has an important influence on the running of the robot, which in tum may affect the production. The principle of the controller, therefore, should be fully understood and mastered. no structure and working principle of Type of Panadac399 of SCARA Industry Robot is analyzed in this paper, which can provide references for the future design, mounting, debugging and improvement of the same type of robot controller or numerical control machines.
Xue Zhou,Dongxin Liang,Qing Li,Lanbo Zhao,Yadi Bin,Feng Ma,Rongqian Wu,Yi Lv,Qiling Li 대한부인종양학회 2023 Journal of Gynecologic Oncology Vol.34 No.6
Objective: Traditional uterine manipulator is considered as the main reason for short survival of patients with early-stage cervical cancer during minimally invasive surgery. This study aims to assess the sealing effect of magnetic-sealing uterine manipulators (MUMs) in isolated uteruses. Methods: The study was performed on isolated uterus from patients with early-stage cervical cancer who underwent open abdominal radical hysterectomy between November 2019 to April 2021. Right-angle forceps closure tests (groups 1 and 3) were defined as control tests. One experimental MUM closure test (group 2) and 2 control tests were respectively carried out in each of the isolated uterus. DNA ploidy analysis system was used to observe exfoliated cells. Statistical analysis was performed using Wilcoxon signed-rank test to assess the sealing effect of MUM. Results: We identified 36 patients. No regional node metastasis was discovered and only one tumor was larger than 4.0 cm in diameter. The mean of exfoliated tumor cells in groups 1, 2, and 3 were 1, 1, and 2, respectively. There was no significant difference in the quantity of exfoliated cells between groups 1 and 3 (p=0.476), so the results of the 2 groups were merged. Subsequently, a significant difference was observed between combined right-angle forceps closure tests and MUM closure tests (p=0.022). Conclusion: The sealing effect of MUM was better than that of right-angle forceps. MUM can effectively seal cervical cancer cells in the cup cover, avoiding the dissemination of tumor cells.
Research on the Improved Way of RED Algorithm S-RED
ZHAO Yu-hong,ZHENG Xue-feng,TU Xu-yan 보안공학연구지원센터 2016 International Journal of u- and e- Service, Scienc Vol.9 No.2
In order to improve sensitivity of parameter and network load, an improved random early detect ion (RED) mechanism orienting to stability, which is named extended stability of random early detection ( S-RED) , was proposed. This algorithm sectionally calculates the probability of packet loss by using the quadratic function to make its variability smoother, meanwhil ,and simplify the calculation formula ofprobability by decreasing the number of parameters in the calculation to properly weaken the performance influence due to parameter settings. We tested our proposed algorithm using the Network Simulator version 2 (ns-2) and found that it shows better stable performance than other typical RED variants and close throughput.
Zhao, Yong-Qiang,Feng, Hui-Wei,Jia, Tao,Chen, Xue-Mei,Zhang, Hui,Xu, An-Ting,Zhang, Hai-Ling,Fan, Xian-Liang Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.12
Background: To investigate the effect of celecoxib on telomerase activity and apoptosis in a human laryngeal squamous carcinoma cell line (Hep-2 cells). Materials and Methods: The growth inhibition rate of Hep-2 cells in vitro was measured by MTT assay, and apoptosis by TUNEL assay and flow cytometry (FCM). The TRAP-ELISA method was used to determine telomerase activity in Hep-2 cells. The mRNA expression of human telomerase RNA component(hTR), human telomerase reverse transcriptase (hTERT) and human telomerase-associated protein(hTEP1) was determined by RT-PCR assay. Expression of Bax and Bcl-2 proteins was assessed by Western blotting. Results: Celecoxib can inhibit proliferation and induce apoptosis in a dose- and time-dependent manner, repress telomerase activity, decrease hTERT mRNA and Bcl-2 protein expression and increase Bax protein expression, PGE2 had no effect on telomerase. Conclusions: Celecoxib had the antiproliferative and pro-apoptotic effect in Hep-2 cells. Apoptosis was accompanied by a decrease in telomerase activity which was directly correlated with hTERT mRNA and up-regulation of Bax/Bcl-2. Bcl-2 may thus play an important role in telomerase activity as well as apoptosis.
Xue-Feng Zhang,Anjiang Cai,Yulong Zhao 한국정밀공학회 2018 International Journal of Precision Engineering and Vol.19 No.4
This paper provides a comprehensive study on the zero potential method for restriction of the crosstalk-based measurement error in network resistor arrays. We introduce four circuits with different architectures based on the zero potential method to comparatively study the effect of the switches on-resistance on the measurement error. Moreover, the effect of the operational amplifiers with different specifications on the measurement error will be investigated. The results show that the measurement error introduced by the onresistance of the switches can be effectively suppressed by inserting a buffer between the sensing elements and the switches on each driven electrode, and utilizing the virtual ground of the trans-impedance amplifier on each scanned electrode. We will show that, the efficiency of the circuits on elimination of the measurement error may be improved by employing high precision operational amplifiers.
A new algorithm of abstracting numeric image outline
Xiao-Feng Shang,Xue-Heng Tao,Xin Zhao,Jin-Shi Lu 한국멀티미디어학회 2006 한국멀티미디어학회 국제학술대회 Vol.2006 No.-
A new algorithm based on iterative-dynamic algorithm and edge detection algorithm has been formulated in this paper. In the experiment, the binary image was first introduced by iterative-dynamic threshold algorithm, which had a good performance in restraining noise. Gauss filter was then applied to the binary image in order to eliminate some false edge pixels; statistic and differential coefficient methods were used for calculating the grads-in-image of scope and direction. The object edge was hereby detected and abstracted by using double threshold. Compared with traditional edge abstraction algorithm, the algorithm is advanced in solving the main problem that traditional edge abstraction was in the face of. By reason of using iterative-dynamic algorithm in the first step, it has perfect quality in restraining variety of disturbing factor, like random noise, optic distortion, light intensity and so on. Due to the application of statistic and differential coefficient, the perfect outcome was realized. The results of experiments have indicated that the edge of complex image can be precisely abstracted and the drawbacks of traditional edge detection algorithm can be thoroughly overcome by means of this method.