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      • KCI등재

        Prediction of Equivalent Chloride Ion Diffusion Coefficient in Cracked Concrete of the in-Service RC Element

        Xiao-Hui Wang,Dong-Gang Hu,Ahmad Kueh Beng Hong,Dan-Da Shi 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.5

        Considering the influence of the visible load-induced transverse cracks on chloride ion diffusion in cracked concrete of the in-service reinforced concrete (RC) elements under marine environment, a typical concrete volume with one transverse crack was taken to establish the governing equation. Assuming the crack widths at the outer lateral and bottom surfaces were equal, a model to predict the equivalent chloride diffusion coefficient in cracked concrete was put forward to consider the influence of the average transverse crack width, crack spacing and crack extending lengths in beam height and width directions on chloride diffusion. Results show that the proposed model can better reflect the variation trend of the equivalent chloride diffusion coefficient with different crack widths in in-service RC elements under marine environment.

      • SCIESCOPUSKCI등재

        Ordinal Optimization Theory Based Planning for Clustered Wind Farms Considering the Capacity Credit

        Wang, Yi,Zhang, Ning,Kang, Chongqing,Xu, Qianyao,Li, Hui,Xiao, Jinyu,Wang, Zhidong,Shi, Rui,Wang, Shuai The Korean Institute of Electrical Engineers 2015 Journal of Electrical Engineering & Technology Vol.10 No.5

        Wind power planning aims to locate and size wind farms optimally. Traditionally, wind power planners tend to choose the wind farms with the richest wind resources to maximize the energy benefit. However, the capacity benefit of wind power should also be considered in large-scale clustered wind farm planning because the correlation among the wind farms exerts an obvious influence on the capacity benefit brought about by the combined wind power. This paper proposes a planning model considering both the energy and the capacity benefit of the wind farms. The capacity benefit is evaluated by the wind power capacity credit. The Ordinal Optimization (OO) Theory, capable of handling problems with non-analytical forms, is applied to address the model. To verify the feasibility and advantages of the model, the proposed model is compared with a widely used genetic algorithm (GA) via a modified IEEE RTS-79 system and the real world case of Ningxia, China. The results show that the diversity of the wind farm enhances the capacity credit of wind power.

      • Efficacy and Safety of Sorafenib for Advanced Non-Small Cell Lung Cancer: a Meta-analysis of Randomized Controlled Trials

        Wang, Wei-Lan,Tang, Zhi-Hui,Xie, Ting-Ting,Xiao, Bing-Kun,Zhang, Xin-Yu,Guo, Dai-Hong,Wang, Dong-Xiao,Pei, Fei,Si, Hai-Yan,Zhu, Man Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.14

        Background: Many clinical trials have been conducted to evaluate sorafenib for the treatment of advanced NSCLC, but the results for efficacy have been inconsistent. The aim of this study was to evaluate the efficacy and safety of sorafenib in patients with advanced NSCLC in more detail by meta-analysis. Methods: This meta-analysis of randomized controlled trials (RCTs) was performed after searching PubMed, EMBASE, ASCO Abstracts, ESMO Abstracts, and the proceedings of major conferences for relevant clinical trials. Two reviewers independently assessed the quality of the trials. Outcomes analysis were disease control rate (DCR), progression- free survival (PFS), overall survival (OS) with 95% confidence intervals (CI) and major toxicity. Subgroup analysis was conducted according to sorafenib monotherapy, in combination with chemotherapy or EGFR-TKI to investigate the preferred therapy strategy. Results: Results reported from 6 RCTs involving 2, 748 patients were included in the analysis. Compared to sorafenib-free group, SBT was not associated with higher DCR (RR 1.31 (0.96- 1.79), p=0.09), PFS (HR 0.82 (0.66-1.02), p=0.07) and OS (HR 1.01 (0.92-1.12), p=0.77). In terms of subgroup results, sorafenib monotherapy was associated with significant superior DCR and longer PFS, but failed to show advantage with regard to OS. Grade 3 or greater sorafenib-related adverse events included fatigue, hypertension, diarrhea, oral mucositis, rash and HFSR. Conclusions: SBT was revealed to yield no improvement in DCR, PFS and OS. However, sorafenib as monotherapy showed some activity in NSCLC. Further evaluation may be considered in subsets of patients who may benefit from this treatment. Sorafenib combined inhibition therapy should be limited unless the choice of platinum-doublet regimen, administration sequence or identification of predictive biomarkers are considered to receive better anti-tumor activity and prevention of resistance mechanisms.

      • SCIESCOPUSKCI등재

        Relationship between Differential Gene Expression in Ovary and Heterosis of Egg Number Traits in a Chicken Diallel Cross

        Wang, Hui,Sun, Dong-Xiao,Yu, Ying,Wang, Dong,Zhang, Yuan Asian Australasian Association of Animal Productio 2005 Animal Bioscience Vol.18 No.6

        In order to understand the molecular basis of chicken heterosis in reproduction traits, mRNA differential display (DDRT-PCR) methods were used to analyze the differential gene expression of ovary tissue between hybrids and their parental lines in a 4${\times}$4 diallel cross, involving 4 chicken breeds, which were White Plymouth Rock (E), CAU Brown (D), Silkies (C) and White Leghorn (A). Total of 331 differential displayed cDNA bands from 1,161 were displayed in the 4${\times}$4 diallel cross combinations with 30 pairs of primers, which shows the differences of gene expression between hybrids and their parental lines were very obvious in quantity and quality. Seven types of differential expression patterns were found: Co-dominance expressed pattern (T1), under-expression of parental fragments in hybrids (T2), over-expression of parental fragments in hybrids (T3), hybrid-absence expressed pattern (T4), single parentspecific expressed pattern (T5), dominant expression fragments of single parent in hybrids (T6), hybrid-specific expressed pattern (T7). Correlation analysis indicated that there were significant correlations between the pattern of T3 and the heterosis percentage of egg number of 32-week and 42-week old chickens(p<0.01), while there were negative significant correlations between the pattern of T7 and the heterosis percentage of egg number of 32-week and 42 week-old birds (p<0.01).

      • KCI등재

        Influence of different fatigue loads and coating thicknesses on service performance of RC beam specimens with epoxy-coated reinforcement

        Xiao-Hui Wang,Yang Gao,Run-Dong Gao,Jing Wang,Xi-La Liu 사단법인 한국계산역학회 2017 Computers and Concrete, An International Journal Vol.19 No.3

        Epoxy-coated reinforcing bars are widely used to protect the corrosion of the reinforcing bars in the RC elements under their in-service environments and external loads. In most field surveys, it was reported that the corrosion resistance of the epoxy-coated reinforcing bars is typically better than the uncoated bars. However, from the experimental tests conducted in the labs, it was reported that, under the same loads, the RC elements with epoxy-coated reinforcing bars had wider cracks than the elements reinforced with the ordinary bars. Although this conclusion may be true considering the bond reduction of the reinforcing bar due to the epoxy coating, the maximum service loads used in the experimental research may be a main reason. To answer these two phenomena, service performance of 15 RC beam specimens with uncoated and epoxy-coated reinforcements under different fatigue loads was experimentally studied. Influences of different coating thicknesses of the reinforcing bars, the fatigue load range and load upper limit as well as fatigue load cycles on the mechanical performance of RC test specimens are discussed. It is concluded that, for the test specimens subjected to the comparatively lower load range and load upper limit, adverse effect on the service performance of test specimens with thicker epoxy-coated reinforcing bars is negligible. With the increments of the coating thickness and the in-service loading level, i.e., fatigue load range, load upper limit and fatigue cycles, the adverse factor resulting from the thicker coating becomes noticeable.

      • Susceptibility Loci Associations with Prostate Cancer Risk in Northern Chinese Men

        Wang, Na-Na,Xu, Yong,Yang, Kuo,Wei, Dong,Zhang, Yao-Guang,Liu, Ming,Shi, Xiao-Hong,Liang, Si-Ying,Sun, Liang,Zhu, Xiao-Quan,Yang, Yi-Ge,Tang, Lei,Zhao, Cheng-Xiao,Wang, Xin,Chen, Xin,Hui, Juan,Zhang, Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.5

        Background: KLK3 gene products, like human prostate-specific antigen (PSA), are important biomarkers in the clinical diagnosis of prostate cancer (PCa). G protein-coupled receptor RFX6, C2orf43 and FOXP4 signaling plays important roles in the development of PCa. However, associations of these genes with PCa in northern Chinese men remain to be detailed. This study aimed to investigate their impact on occurrence and level of malignancy. Methods: All subjects were from Beijing and Tianjin, including 266 cases with prostate cancer and 288 normal individuals as controls. We evaluated associations between clinical covariates (age at diagnosis, prostate specific antigen, Gleason score, tumor stage and aggressive) and 6 candidate PCa risk loci, genotyped by PCR- high resolution melting curve and sequencing methods. Results: Case-control analysis of allelic frequency of PCa associated with PCa showed that one of the 6 candidate risk loci, rs339331 in the RFX6 gene, was associated with reduced risk of prostate cancer (odds ratio (OR) = 0.73, 95% confidence interval (CI) =0.57-0.94, P = 0.013) in northern Chinese men. In addition, subjects with CX (CC+TC) genotypes had a decreased risk for prostrate cancer compared to those carrying the TT homozygote (OR =0.64, 95% CI = 0.45- 0.90, P = 0.008). The TT genotype of 13q22 (rs9600079, T) was associated with tumor stage (P=0.044, OR=2.34, 95% CI=0.94-5.87). Other SNPs were not significantly associated with clinical covariates in prostate cancer (P > 0.05). Conclusions. rs339331 in the RFX6 gene may be associated with prostate cancer as a susceptibility locus in northern Chinese men.

      • KCI등재

        Analysis and Prediction of Regional Land Subsidence with InSAR Technology and Machine Learning Algorithm

        Hui Wang,Chao Jia,Pengpeng Ding,Keyin Feng,Xiao Yang,Xiao Zhu 대한토목학회 2023 KSCE Journal of Civil Engineering Vol.27 No.2

        As a worldwide environmental and geological disaster, land subsidence may cause serious harm to urban development. Therefore, the prediction of land subsidence is a key scientific problem. Decheng county, Shandong Province in China is taken as the research object. Based on BP neural network (BPNN) and random forest (RF) method, the analysis and prediction of regional land subsidence are carried out by applying multi-source monitoring data, Geographic Information System (GIS), and machine learning algorithm. Combined with Short Baseline Synthetic Aperture Interferometric Radar (SBAS-InSAR) and GIS technology, the spatio-temporal evolution characteristics of land subsidence from 2017 to 2020 are analyzed. The impact of different groundwater levels on land subsidence is quantitatively analyzed by BPNN and RF algorithm. The real-time prediction model of regional land subsidence is established. The results show that: 1) The area with the most serious land subsidence is located in Songguantun town, the maximum annual average subsidence rate is -40.71 mm/yr. 2) Land subsidence is mainly affected by deep groundwater and shallow groundwater in the research area. 3) The accuracy of the prediction results of the BPNN model is higher than that of the RF model when groundwater level change is used to predict land subsidence.

      • KCI등재

        Detection of HF-ERW Status by Neural Network on Imaging

        Hui-Feng Wang,Jing Cao,Xiangmo Zhao,Xiao-Meng Wang,Gui-Ping Wang 한국정밀공학회 2017 International Journal of Precision Engineering and Vol.18 No.7

        To achieve online testing of high-frequency electric resistance welding (HF-ERW) tube quality, forecasting models were established for welding defect conditions with collected high-speed images of the joint melting phenomenon, based on a radial basis function neural network (RBFNN). Firstly, the dimensions of the collected image samples were deduced by principal component analysis (PCA). Then, the reduced-dimension image samples were set as inputs of both BPNN (back-propagation neural network) and, for comparison, RBFNN, which were trained so that the model parameters were optimized. Finally, the testing sample set was identified by trained networks. The experimental results show that RBFNN had better generalization ability for HF-ERW images than BPNN, which meant that the recognition rate of low-heat input status reached 100%, while the recognition rate of overheating input status reached 97.67%. They also show that the welding quality detection system based on a neural network is very effective and has a strong guiding significance for welding quality control.

      • SCISCIESCOPUS

        Artificial Noise Assisted Secure Transmission for Distributed Antenna Systems

        Wang, Hui-Ming,Wang, Chao,Ng, Derrick Wing Kwan,Lee, Moon Ho,Xiao, Jia Institute of Electrical and Electronics Engineers 2016 IEEE transactions on signal processing Vol.64 No.15

        <P>This paper studies the artificial noise (AN) assisted secure transmission for a distributed antenna systems (DAS). To avoid a significant overhead caused by full legitimate channel state information (CSI) acquisition, tracking and collection in the central processor, we propose a distributed AN scheme utilizing the large-scale CSI of the legitimate receiver and eavesdropper. Our objective is to maximize the ergodic secrecy rate (ESR) via optimizing the power allocation between the confidential signal and AN for each remote antenna (RA) under the per-antenna power constraint. Specifically, exploiting random matrix theory, we first establish an analytical expression of the achievable ESR, which leads to a non-convex optimization problem with multiple non-convex constraints in the form of high-order fixed-point equations. To handle the intractable constraints, we recast it into a max-min optimization problem, and propose an iterative block coordinate descent (BCD) algorithm to provide a stationary solution. The BCD algorithm is composed of three subproblems, where the first two subproblems are convex with closed-form solutions, and the last one is a convex-concave game whose saddle-point is located by a tailored barrier algorithm. Simulation results validate the effectiveness of the proposed iterative algorithm and show that our scheme not only reduces the system overhead greatly but also maintains a good secrecy performance.</P>

      • KCI등재후보

        Predicting the flexural capacity of RC beam with partially unbonded steel reinforcement

        Xiao-Hui Wang,Xi-La Liu 사단법인 한국계산역학회 2009 Computers and Concrete, An International Journal Vol.6 No.3

        Due to the reduction of bond strength resulting from the high corrosion level of reinforcing bars, influence of this reduction on flexural capacity of reinforced concrete (RC) beam should be considered. An extreme case is considered, where bond strength is complete lost and/or the tensile steel are exposed due to heavy corrosion over a fraction of the beam length. A compatibility condition of deformations of the RC beam with partially unbonded length is proposed. Flexural capacity of this kind of RC beam is predicted by combining the proposed compatibility condition of deformations with equilibrium condition of forces. Comparison between the model’s predictions with the experimental results published in the literature shows the practicability of the proposed model. Finally, influence of some parameters on the flexural capacity of RC beam with partially unbonded length is discussed. It is concluded that the flexural capacity of the beam may not be influenced by the completely loss of bond of the whole beam span as long as the tensile steel can yield; whether or not the reduction of the flexural capacity of the beam resulting from the loss of bond over certain length may occur depends on the detailed parameters of the given beam.

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