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- 저자 : ( Xian Qiao Zeng ) (검색결과 3 건)
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Three-Dimensional Stability of Cyclical Footage Area in Tunnel Face
Qiao Liang,Jie Liu,Jun Wang,Xian-Tao Zeng,Shuo-Guo Wu 대한토목학회 2022 KSCE JOURNAL OF CIVIL ENGINEERING Vol.26 No.2
Based on the theory of limit and the unified strength theory, the three-dimensional failure pattern and the corresponding velocity field on the heading face for cyclical footage are proposed, considering the influence of the cyclical footage and the intermediate principle stress on the heading face stability. Addition, the influence of various parameters on the heading face stability is analyzed. The present study shows that the first increase in internal friction angle (lower than 25°) can promote the heading face stability. Then, the increase in the cohesion can promote the stability when the internal friction angle is higher than 25°. In addition, for the relatively intact instead of the poor surrounding rock, the promotion of the stress conditions of the heading face, caused by by the intermediate principle stress, indicates that the Mohr-Coulomb criterion is conservative.
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Novel Phage Display-Derived H5N1-Specific scFvs with Potential Use in Rapid Avian Flu Diagnosis
( Jie Wu ),( Xian Qiao Zeng ),( Hong Bin Zhang ),( Han Zhong Ni ),( Lei Pei ),( Li Rong Zou ),( Li Jun Liang ),( Xin Zhang ),( Jin Yan Lin ),( Chang Wen Ke ) 한국미생물 · 생명공학회 2014 Journal of microbiology and biotechnology Vol.24 No.5
The highly pathogenic avian influenza A (HPAI) viruses of the H5N1 subtype infect poultry and have also been spreading to humans. Although new antiviral drugs and vaccinations can be effective, rapid detection would be more efficient to control the outbreak of infections. In this study, a phage-display library was applied to select antibody fragments for HPAI strain A/Hubei/1/2010. As a result, three clones were selected and sequenced. A hemagglutinin inhibition assay of the three scFvs revealed that none exhibited hemagglutination inhibition activity towards the H5N1 virus, yet they showed a higher binding affinity for several HPAI H5N1 strains compared with other influenza viruses. An ELISA confirmed that the HA protein was the target of the scFvs, and the results of a protein structure simulation showed that all the selected scFvs bound to the HA2 subunit of the HA protein. In conclusion, the three selected scFVs could be useful for developing a specific detection tool for the surveillance of HPAI epidemic strains.
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Effective Coupling of a Topological Corner-state Nanocavity to Various Plasmon Nanoantennas
Na Ma,Ping Jiang,You Tao Zeng,Xiao Zhen Qiao,Xian Feng Xu 한국광학회 2022 Current Optics and Photonics Vol.6 No.5
Topological photonic nanocavities are considered to possess outstanding optical performance, and provide new platforms for realizing strong interaction between light and matter, due to their robustness to impurities and defects. Here hybrid plasmonic topological photonic nanocavities are proposed, by embedding various plasmon nanoantennas such as gold nanospheres, cylinders, and rectangles in a topological photonic crystal corner-state nanocavity. The maximum quality factor Q and minimum effective mode volume V eff of these hybrid nanocavities can reach the order of 10 4 and 10 −4 (λ /n) 3 respectively, and the high figures of merit Q/V eff for all of these hybrid nanocavites are stable and on the order of 10 5(λ /n) −3 . The relative positions of the plasmon nanoantennas will influence the coupling strength between the plasmon structures and the topological nanocavity. The hybrid nanocavity with gold nanospheres possesses much higher Q, but relatively large V eff . The presence of a gold rectangular structure can confine more electromagnetic energy within a smaller space, since its V eff is smallest, although Q is lowest among these structures. This work provides an outstanding platform for cavity quantum electrodynamics and has a wide range of applications in topological quantum light sources, such as single-photon sources and nanolasers.
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