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메스암페타민 사용 환자의 정신과적 증상에 영향을 미치는 요인
이춘우,권성민,조성남,권도훈,임효덕,이성국 대한생물치료정신의학회 2004 생물치료정신의학 Vol.10 No.1
목 적 : 본 연구는 메스암페타민 남용 또는 의존 환자의 사회인구학적 특성과 이에 따른 동반된 정신장애를 알아보고, 메스암페타민 사용이 정신과적 증상에 미치는 영향을 알아보기 위함이다. 방 법 : 2002년 7월부터 2003년 7월까지 국립부곡병원 약물중독진료소에 입원한 환자 중 DSM-Ⅳ 진단 기준에 의하여 메스암페타민 남용 또는 의존으로 진단된 44명의 남자 환자를 대상으로 사회인구학적 변인과 물질 의존의 병력, SCL-90-R, BPRS, HRSD, YMRS, Impulsive scale 등을 측정하였다. 결 과 : 메스암페타민 사용 환자들의 93.2%가 우울하였으며, 59.1%는 치료가 필요한 정도의 우울증을 가지고 있었다. 20대 연령층에서는 대인예민성, 적대감 및 공포증에서 유의하게 높았고, 중졸 이하의 교육 수준에서는 대인예민성, 충동성에서 유의하게 높았으며, 무직인 경우는 강박증, 불만, 적대감 및 조중 척도에서 유의하게 높았다. 처음 사용한 연령은 사용 횟수, 유병 기간과 유의한 상관 관계를 보였으나, 수감 횟수와는 낮은 상관 관계를 보였다. 사용 횟수와 적대감, 공포증, 편집증은 서로 유의한 정상관을 보였다. 우울증 척도와 정신병 척도 및 충동성 척도는 서로 유의한 정상관을 보였다. 100회 미만보다 500회 이상 사용했을 경우에 불안, 적대감, 공포증 및 편집증에서 유의하게 높았다. 결 론 : 메스암페타민 남용 또는 의존 환자에서 우울증 유병률이 매우 높게 나타났고, 20대 연령층과 중졸 이하의 교육 수준 그리고 무직인 경우 정신과적 증상이 많이 동반되었으며, 사용 횟수에 따라 불안, 적대감, 공포증, 편집증에서 유의한 차이를 보였다. 그러므로 모든 메스암페타민 사용자에 대해 적절한 정신과적 평가가 필요할 것으로 생각한다. Objectives : The purpose of this study was to examine the sociodemographic characteristics and the comorbid psychiatric disorders and the effect of methamphetamine use on psychiatric symptoms in methamphetamine abuse or dependent patients. Methods : The study subjects were 44 hospitalized male patients who met the DSM-Ⅳ criteria for methamphetamine abuse or dependence. The study included items assessing the sociodemographic profiles, history of substance use, and psychiatric symptomatology. Psychiatric assessments were based on SCL-90-R, BPRS, HRSD, YMRS and Impulsive scale. Results : In methamphetamine use patients, 93.2% were depressed and 59% had moderate to severe depression There were significant differences in interpersonal- sensitivity, hostility and phobia in the 3rd decade age group, interpersonal-sensitivity and impulsive scale in .under the middle school education group, and obsession-compulsion, anxiety, hostility and. YMRS in no-job group, respectively compared to the other groups. Age of the first use was correlated with the frequency of use, and also with the duration of illness, but not with the number of incarceration. There were positive correlations among HRSD, BPRS and impulsive scale. In the above 500 times used group there were significant differences in anxiety, hostility, phobia and paranoia compared to the below 100 times used group. Conclusion : In methamphetamine abuse or dependent patients, the incidence rate of comorbid depression was 93.2%. In the 3rd decade age group, under the middle school education group and no-job group showed higher diverse psychiatric symptoms compared to the other groups. Frequency of use was positively correlated with the symptoms such as anxiety, hostility, phobia and paranoia. We suggest that relevant psychiatric evaluations are needed for all methamphetamine users.
한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고
양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1
The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.
서울의 Penicillinase Producing Neisseria Gonorrhoeae 발생빈도(1996)
김재홍,황동규,전재홍,김윤석,김중환,김용준,이창균,임동진,김현수,조창근,김경문,박상훈,전우형,김희성,이호정,차명수,김갑형,김형석,김석우,황지환,박병순,권오상,이민수,송기훈,성소영,이인섭,부태성 대한화학요법학회 1999 대한화학요법학회지 Vol.17 No.2
Background : In recent years, gonorrhea has been panedemic and remains one of the most commom STDs in the world, especially in developing countries. Objective & Methods: For the detection of a more effective therapeutic regimen and assessing the prevalence of PPNG, we have been trying to study the patients who have visited the VD Clinic of Choong-Ku Public Health Center in Seoul since 1980 by means of the chromogenic cephalosporin method. Results: In 1996, 139 strains of N. gonorrhoeae were isolated, among which 53(39.0%) were PPNG. Conclusion: Our results suggests that after a peak of 74.3% in 1993, the prevalence of PPNG in Seoul is gradually declining.
현대건축의 형태표현에 나타난 '낯설게 하기(defamiliarization)'의 경향에 관한 연구
권유경,김성우,김영태 영남대학교 환경문제연구소 2000 環境硏究 Vol.19 No.2
본 연구는 1920년 러시아 문학의 현상으로 나타난 '낯설게 하기'의 이념을 현대건축의 조형표현 및 이론적 상관성으로 관련짓고자 한다. 현대건축에 있어서 중요한 이해와 경향인 '낯설게하기'를 통해 재발견되는 형식적인 표현으로써 현대건축에서 직접적 혹은 간접적으로 인용되고 있다. 내용보다 형식의 문제에 주목했던 러시아 형식주의의 '낯설게(defamiliarization)'을 통하여 현대건축에서 나타나고 있는 복잡성, 다양성, 혼성, 애매성 등을 제(諸)특성으로 보고, '낯설게 하기'의 목적과 수법들을 조형예술의 표현 특성 및 조형이념과 관련하여 건축적인 체계로 유형화하고 현대건축에서 나타나고 있는 경향 및 형태표현을 파악하는데 그 의의를 두고자 한다. This study related the idea of 'defamiliarization' in 1920's Russian Literature to the phenomenon of modern architecture and analyzed formative expression and theoretical correlativity. It is significant to understand the tendency of modern 'defamiliarization' which has comparatively been cited many times and expressed directly or indirectly in modern architecture. Expecially the 'defamiliarization' theory, with the experimental spirit of Russia constructivism, connected to formative art and can be related to the feature of complexity, variety, perplexity, conceptualization which are prominent in modern architecture. The meaning of 'defamiliarization' involves all the meanings of something new, creative, progressive and throughout this pursuing destruction of fixed idea, inhered newness, deautomatism in the process of consciousness usual environment, subconsciousness. This become the motive which formed important basis of making a new ideology in the formative art since Avant-garde and this logic offers theoretical basis correlated the Avant-garde spirit as a stream of breaking the existing convention.
權俊五,林相鎬,金宇赫 조선대학교 국토개발연구소 1995 국토개발연구 Vol.15 No.2
This study groups the cities by function with standard deviation and multi-variable analysis using the rate of industrial employees selected from city-level cities in Korea and the results are arranged as follows. First, in classifying the cities by standard deviation, the cities showing relatively specialized industry in comparison with other cities and the employment rate more than M+2SD are Ku-mi and Kim-hae cities in the part of manufacturing in 1981, Nam-won city in that of construction in 1981, Dong-hae city in finance, insurance, real estate and other service industries in 1981, and Kumi-city in manufacturing industry, Chung-mu, Chung-ju and Seo-kywipo cities in warehouse, transportation and communication industry, Pohang city in finance, insurance, real estate and other service industries and Tae-baek city in social and personal service industries in 1991. Second, the cities having more than M+3SD can be interpreted that they are extremely specialized in the related industry in comparison with other cities and Kun-san and In-chon cities were classified in the construction an Che-ju and Seo-Kywipo cities in social and personal service industries in 1981 and Kim-Hae city was classified in manufacturing industry and Inchon in the construction in 1991. Third, as a result of executing the cluster analysis, the cities which belong to the first group are Su-won, Sung-nam and Ahn-yang and those that belong to the second group are Mok-po, Kwa-chun and Choon-chun.
砂耕栽培에 있어서 질소 및 칼리의 施肥水準의 오이의 生育, 收量 및 無機成分吸收에 미치는 影響
權成煥,鄭淳宰,具禹書,鄭景泰 東亞大學校 大學院 1993 大學院論文集 Vol.18 No.-
This experiment was conducted to study the effect of Nitrogen and Potassium treatment on growth, yield and content of mineral elements the results were summarized as follows; 1. Growth and Yields were more effective in N treatment with 8g per plant, were more effective in K treatment with 16 me per liter 2.Content of mineral elements in leaves were a lot of N and MG in N treatment, were a lot of P content in K treatment. 3. The content of mineral of Petiol, fruit and Xyleme sap. N and K were more contented in petiole, as the others were more contented in Xyleme sap. Ca was contented a little in fruit. 4. Absorption of water was increased in the N treatment with 8g per plants, in the K treatment with 16 me liter. The contents of chlorophyll was increased as the level of Nitrogen was increased in N treatment while, decreased on young leave in K treatment.
임상검체에서 분리된 그람 음성 세균들에 대한 Isepamicin의 시험관내 항균력
권현희,박수진,소민욱,박현구,최성호,김미나,최상호,정진용,우준희,김양수 대한감염학회 2006 감염과 화학요법 Vol.38 No.6
Background : The increasing incidence of multidrug-resistant gram-negative bacteria causing nosocomial infections is an important clinical problem. Isepamicin is a recently developed aminoglycoside which has been known to have potent activity against gram-negative organisms. We evaluated the in vitro activities of isepamicin and other aminoglycosides against a large number of gram-negative organisms. Materials and Methods : We tested the in vitro antimicrobial activities of isepamicin, amikacin, gentamicin, and tobramycin against 566 gram-negative organisms collected between January 2006 and June 2006 in Asan Medical Center. Minimal inhibitory concentrations (MICs) were determined and interpreted according to the recommendations of Clinical and Laboratory Standard Institute (CLSI). The breakpoint MIC used for interpretation of isepamicin was MIC≤16 ㎍/mL as susceptible, 32 ㎍/mL as intermediate, and 64 ㎍/mL as resistant. Results : The MIC_(50)/MIC_(90) of isepamicln for Escherichia coli, Klebsiella pneumon/ae, Pseudomonas aeruginosa, Acinetobacter baumannii, and Enterobacter cloacae were 1/2, 0.5/>128, 4/16, 16/>128, and 1/2 ㎍/mL, respectively. The susceptibilities for E. coli, K. pneumoniae, P. aeruginosa, A. baumannii, and E. cloacae were 100%, 86.4%, 89.7%, 50.0%, and 96.6%, respectively. For E. coli, K. pneumoniae, P. aeruginosa, and E. cloacae, isepamicln had better in vitro activities than gentamicin and tobromycin, and had similar activities with amlkacin. For A. baumanii, all four tested aminoglycosides had similar in vitro activities. Conclusion : Isepamicin had excellent in vitro activities against gram-negative organisms, except A. baumanii. The overall in vitro activities were similar with amikacin. 목적 : 그람 음성 세균은 다양한 지역사회 및 병원 획득 감염의 원인균이다. 최근에는 병원 감염을 일으키는 그람 음성 세균에서 항균제 내성균의 출현과 확산이 큰 문제가 되고 있다. Isepamicin은 최근에 소개된 gentamicin B의 유도체로 외국에서의 연구에 의하면 그람 음성 세균들에 대한 항균력이 우수함이 보고 된 바 있다. 본 연구에서는 우리나라의 임상 균주들을 대상으로 그람 음성세균에서 isepamicin의 시험관내 항균력을 기존의 아미노배당체 제재들과 비교하여 평가하고자 하였다. 재료 및 방법 : 2006년 1월에서 6월 사이에 서울아산병원 환자에서 분리된 Escherichia coli 113 균주, Klebsiella pneumoniae 110 균주, Pseudomonas aeruginosa 117 균주, Acinetobacter baumannii 108 균주, 그리고 Enterobacter cloacae 118 균주를 대상으로 isepaimcin, amikacin, gentamicin, tobramycin에 대한 최소억제농도(minimal inhibitory concentration, MIC)를 한천 희석법(Mueller-Hinton Agar)을 이용하여 측정하였다. 감수성여부는 CLSI 기준에 따랐으며, isepamicin은 MIC≤16㎍/mL를 감수성, MIC=32 ㎍/mL를 중등도 내성, MIC≥64 ㎍/mL를 내성으로 판정하였다. 결과 : Isepamicm의 E. coli, K. pneumoniae, P. aeruginosa, A baumannii, E. cloacae에 대한 MIC_(50)/MIC_(90)은 각각 1/2, 0.5/>128, 4/16, 16/>128, 1/2 ㎍/mL였고, 항균제 감수성률은 차례대로 100%, 86.4%, 89.7%, 50.0%, 96.6%였다. 기존 아미노배당체 제재들과 비교하면 E. coli, K. pneumoniae, P. aeruginosa, E. cloacae에서는 amikacin과 비슷한 감수성률을 보였고, gentamicin과 tobramycin보다 높은 감수성률을 보였다. A baumannii의 경우 isepamicin의 감수성률이 50.0%로 비교적 낮았지만 amikacin, gentamicin, tobramycin도 각각 50.0%, 46.3%, 47.2%의 감수성률을 나타내어 4가지 항균제가 모두 비슷한 항균력을 보였다. 결론 : Isepamicin은 그람 음성 세균들에 있어 기존의 아미노배당체 제재들과 비교했을 때 amikacin과는 동등한 시험관내 항균력을 보이고 gentamicin, tobramycin보다 뛰어난 시험관내 항균력을 보여 사용이 유망한 아미노배당체 중 하나라 생각된다.
권영준,한상우,한선호 순천향대학교 1990 논문집 Vol.13 No.1
The psychosocial stressors experienced in the 6 months prior to the admission were studied in 62(27 male and 35 female) inpatients who mets DSM-Ⅲ criteria for bipolar disorder and were hospitalized in the Neuropsychiatric department of Soonchunhyang University Hospital from January 1987 to August 1989. The results were as follows; 1. Among the 249 cases, 36(58.1%) cases had the psychosocial stressors prior to admission. 2. 40.7% of male cases and 71.4% of female cases had the psychosocial stressors prior to admission. Female cases had significantly higher relation to the psychosocial stressors. 3. By the age variable, there was not significant difference in relation to the psychosocial stressors prior to admission. 4. By the different educational level, there was not significant difference in relation to psychosocial stressors prior to admission. 5. By the occupation variable, there was not significant difference in relation to the psychosocial stressors prior to admission. 6. The frequency of the psychosocial stressors was in the order of occupational problems(36.1%), other interpersonal problems(22.1%), financial problems(11.1%) conjugal problems(11.1%).