Poster Session : PS 0831 ; Upper GI Tract : Clinical Factors to Predict Angiographically Detectable Non-Variceal Upper Gastrointestinal Bleeding in Patients Refractory to Endoscopic Treatment

( Tae Hwan Ha ),( Tae Hoon Oh ),( Sung In Yu ),( Min Kim ),( Jong Wook Kim ),( Won Ki Bae ),( Jae Hyung Kim ),( Seung Suk Baek ),( Mi Jin Ryu ),( Ye Na Choi ),( Ji Young Park ),( Eileen L Yoon ),( Tae 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1

Background: Non-variceal upper GI bleeding (NVUGIB) is a common medical problem that has signifi cant association with morbidity and mortality. Angiographic detection and subsequent transarterial embolization (TAE) is a primary treatment option when medical and endoscopic treatments fail. We investigated clinical factors that could affect the success of the angiographic detection and prognosis after TAE in patients with NVUGIB refractory to endoscopic therapy. Methods: A retrospective analysis of the clinical data was done in patients with failed endoscopic treatment who underwent angiography for the treatment of acute NVUGIB between May 2002 and May 2013. Patients were divided into detection or non-detection groups according to the presence of bleeding stigmata in angiographic fi nding. Rebleeding defi ned as subsequent bleeding event within 7 days and mortality within 30days were analyzed as outcome parameters after TAE following detection in angiography. Results: A total 45 patients 37 (male, mean age, 65.9±14.9 years) were analyzed and classifi ed as a detection group (n=25, 55.5%) and non-detection group (n=20, 44.6%). Peptic ulcers were the most common cause of refractory NVUGIB. Larger transfusion amount (5.7±3.9 unit vs. 3.5±2.8 unit; P=0.03), prolonged aPTT level (34.2±17.3 sec vs. 21.8±13.8 sec; P=0.01) and short time interval between last endoscopy and angiography (17.5±25.9 hours vs. 34.3±59.5 hours; P=0.04) were found to be signifi cant factors for predicting angiographic detection. TAE was performed in all patients detected in angiography. Rebleeding (44%) was significantly associated with higher Rockall score (8.3±1.5 vs. 6.6±2.4; P=0.046) and mortality (12%) was signifi cantly associated with higher Rockall score (9.3±0.6 vs. 7.1±2.2; P=0.002) and higher level of BUN (55.3±47.4 vs. 27.6±17.4; P=0.01). Conclusions: Clinical characteristics associated with angiographic detection in patients with NVUGIB refractory to endoscopic therapy were severe bleeding, bleeding tendency and early angiographic intervention. The Rockall score is useful parameter for predicting rebleeding and mortality after TAE.

太極拳의 原理에 關한 硏究

羅大觀,吳旼錫,宋泰元 대전대학교 한의학연구소 2001 혜화의학회지 Vol.10 No.1

Tae-Geuk-Guan(太極拳) Tae-Geuk(太極) is arranged Yum-Yang-O-Hang(陰陽五行) and created from Mu-geuk(無極) means great chaos. Jin-sik Tae-Geuk-Guan(陳式太極拳) has tenth essential theory. There are Li(理), Qi(氣), Samjul(三節), Sacho(四梢), Ojang(五臟), Samhap(三合), Yukjin(六進) Sinbup(身法) Bobup(甫法), Gangyou(剛柔). Li(理) is Rules of all things. Qi(氣) is body. Body is diveided into Samjul(三節), Sacho(四梢), Ojang(五臟) is inside body and make human'sbody and Qi(氣), Samhap(三合) is union of mind & intention, Qi & power, muscle & bone. Yukjin(六進) is movement of body. Sinbup(身法) has Chong(縱), Hoeng(橫), Ko(高), Jeo(低), Jin(進), Toe(退), Ban(反), Chuk(側). Bobup(步法) has Jin(進), Toe(退), Ban(反), Chuk(側). Yang-sik Tae-Geuk-Guan(揚式太極拳) has tenth essential theory. There are Songyo(송腰), Heolungjungkyung(虛靈頂경), Hamhungbalbae(含胸拔背), Chimgyungsuju(沈궁수주), Bunheosil(分虛實), Yongeuibulyonglyuk(用意不用力), sanghasangsu(上下相隋), Naeoesanghap(內外相合), Sangyunbudan(相連不斷), Dongchungguchung(動中求精)

Growth Inhibition of Colon Cancer through Inactivation of STAT3 Pathway by IL-10 and IL-1ra Released from Murine Macrophage

Jin Tae Hong, Dohee Won1, Mi Hee Park, Sun Mi Kown, Miran Jo, Sang-Yoon Nam, Beom Jun Lee, Young Won Yun, Ki-Wan Oh, Sang Bae Han 충북대학교 동물의학연구소 2011 Journal of Biomedical and Translational Research Vol.12 No.4

The objective of this study was to determine the effect of macrophages on growth of human colon cancer cells. The results showed that co-culture of colon cancer cells with macrophages inhibited the growth of colon cancer cells (HCT116 and SW620) depending on the number of macrophages, RAW 264.7 cells, and activated THP-1 cells accompanied by down regulation of pSTAT3 in cancer cells. We also found that expression and release of cancer cell growth inhibitory cytokines, IL-1 receptor antagonist (IL-1ra) and IL-10, was increased in macrophages. Blocking of the STAT3 pathway with specific inhibitor and siRNA of STAT3 abolished the growth of colon cancer cells and expression of IL-1ra and IL-10. In addition, neutralization of IL-1ra and IL-10 with antibodies resulted in reversal of macrophage-induced inhibition of cancer cell growth. These data showed that IL-1ra and IL-10 released from macrophages inhibit growth of colon cancer cells through inhibition of the STAT3 pathway

太極拳의 動作에 關한 硏究

鄭敏燮,吳旼錫,宋泰元 대전대학교 한의학연구소 2001 혜화의학회지 Vol.10 No.1

Through study of movement of Tae-Geuk-Guan(太極拳), we understand Tae-Geuk-Guan(太極拳) & essential movement. Theory about creator of Tae-Geuk-Guan(太極拳) is indistinct. there are Jangsampung-theory(張三豊設), Wangjongak-theory(王宗岳設), Jinwangjung-theory(陳王廷設), Jinbok-theory(陳卜設). Tae-Geuk-Guan(太極拳) is military arts developed before Song empire(宋). Tae-Geuk-Guan(太極拳) has many branch.(Jin-sik陳式, Yang-sik楊式, Mu-sik武式 O-sik吳式, Son-sik孫式) Tae-Geuk-Guan(太極拳) manual movement use fist(拳), palm(掌), hook shape(鉤), its using form has many type like Bung, Yi, Jae, An, Chae, Yul, Ju, Go. Its gait has many type like Sang-bo(上步), Tae-bo(退步), Jin-bo(進步), Deng-gak(댕脚), Bun-gak(分脚), Bak-gak(拍脚). Essential theory of Tae-Geuk-Guan(太極拳) is Yi-Sim-Hang-Gi(以心行氣) & Yi-Gi-Un-Sin(以氣運身). It means mind(心) moves and qi(氣) moves body(身).

청심연자탕(淸心蓮子湯)으로 호전된 뇌내출혈에 고혈압이 동반된 태음인 환자 치험 1례

오정민,엄태민,최고은,허종원,유호룡,설인찬,김윤식,Oh, Jeong-Min,Eom, Tae-Min,Choi, Ko-Eun,Heo, Jong-Won,Yoo, Ho-Ryong,Seol, In-Chan,Kim, Yoon-Sik 대한중풍순환신경학회 2014 대한중풍.순환신경학회지 Vol.15 No.1

■ Objectives The purpose of this case study is to report that a hypertension with intracerebral hemorrhage of tae-eumin was treated with 'Cheongsim Yeunja-tang' and then the symptoms were improved and blood pressure was decreased. ■ Methods Although the patient who had hypertension with intracerebral hemorrhage took antihypertension drugs, intermittent increase of blood pressure was shown. We diagnosed him as Tae-eumin and treated with Cheongsim Yeunja-tang. We daily checked blood pressure and evaluated the symptoms. ■ Results After the treatment with Cheongsim Yeunja-tang, blood pressure was decreased and symptoms were improved. ■ Conclusion The result shows Cheongsim Yeunja-tang has antihypertensive effect and improve hypertension symptoms of Tae-eumin patient with intracerebral hemorrhage.

조르주 바타유의 비정형 개념을 통한 물의 디지털이미지 정형화 연구

염동철 ( Dong Cheol Yoem ),오태원 ( Tae Won Oh ) 한국기초조형학회 2015 기초조형학연구 Vol.16 No.1

본 연구는 조르주 바타유의 ‘비정형’ 개념을 디지털이미지에 도입해 물이라는 소재가 정형화될 수 있는지 그 가능성과 작품사례를 통해 분석해 본 연구이다. 논리적 근거를 제시하기 이전에 바타유 사상의 기저가 되는 유물론과 거기에서 연결되는 비정형의 작동기제 중 ‘저급유물론’과 ‘엔트로피’의 속성을 바타유의 비정형 개념으로 타진해 보았다. 바타유의 비정형 개념은 부아와 크라우스의 「비정형: 사용자 안내서」에 수록된 내용과 크라우스의 해석, 그리고 바타유의 철학적 사유와 함께 분석해 보았으며, 바타유에 의하면 비정형이란 현실을 추상적 개념들에 따라 재조직하고 작은 의미의 단위들로 분해하는 범주들과 형태적 경계들을 파기해버리는 것이며, ‘의미 없는 비개념’이 곧 비정형이다. 따라서 비정형은 스스로는 아무 의미도 갖지 않으면서 기존하는 형태들이 지닌 의미들, 형식적 범주들의 작동을 와해시키는 ``임무``만을 가진 개념이다. 그러한 분석으로 비정형 개념은 디지털이미지와 자연스럽게 연결되고 구동될 수 있는 개념이다. 이러한 비정형의 물은 정형의 대상이 아니므로 디지털매체를 통해 정형화될 수 있는 소지를 내포하고 있는 소재이며, 디지털이미지작업을 통해 독창적인 형태를 구현할 수 있다. 그 예로 작품분석을 통해 각각 획득하고자 하는 이미지를 위해 일련의 설정된 환경과 정형화된 도구들을 수용하였음을 알 수 있었으며, 오태원의 미리 계획된 실험을 통해 투명한 수조와 LED조명이라는 정형화된 도구 사용이 물의 디지털이미지 형태를 훨씬 선명하게 하며 물 이미지를 더욱 부각 시킬 수 있었음을 알 수 있었다. 이 연구가 기존의 디지털 아트 작업을 통한 이미지는 유동적, 가변적, 비정형적일 것이라는 관념을 깨고 오히려 비정형의 매체를 통해서 비정형의 소재가 정형화된 형태를 구축할 수 있다는 새로운 패러다임을 제시한다. A Study on Digital Image Formalism of Water Through the Formless Concept of Georges Bataille This study aims to analyze the possibility of applying the ``formless`` concept of Georges Bataille to digital images and formalizing water as a material, based on the cases of related works. Prior to presenting a logical basis, materialism, which is a base of Bataille thoughts, and the properties of ``base materialism`` and ``entropy`` out of the formless mechanisms connected with materialism were considered as formless concepts. Bataille``s formless concept was analyzed along with the concepts included in the 「Formless: A User’s Guide」 written by Bois and Krauss, Krauss``s interpretation and Bataille``s philosophic thoughts. According to Bataille, ``formless`` is to re-organize the reality depending on abstract concepts and to destroy the categories and morphological boundaries subdivided into small semantic units, and ``meanless non-concept`` is exactly formless. Thus, formless does not have any meaning itself and its concept only performs the ``duty`` to collapse the meanings of the existing forms and the operation of formal categories. Based on that analysis, the formless concept can be naturally interlinked with digital images and operated. In other words. This formless water is not subject to formalism and thus this contains the possibility of being formalized through digital media and can create its own unique form through digital imaging. As an example, it was found that for images to obtain, individual works accepted a series of set environments and standardized tools, and Oh, Tae-won``s previously planned experiment showed that using the standardized tools like transparent water tank and LED lighting could make the digital image of water much clearer, or emphasize the image of water more. In conclusion, this study breaks the idea that digital art images would be fluid, variable and formless and presents a new paradigm that formless materials can create formalized forms through formless media.

마이크로 컴퓨터를 이용한 구형탱크에서의 액위제어

오민,이태희,강원영,신창섭 연세대학교 산업기술연구소 1987 논문집 Vol.19 No.1

The liquid level control of a spherical tank, which changes nonlinearly with the variation of a setpoint, was controlled by a micro-computer using adaptive control theory and the experimentally measured gain value were compared with the theoretically calculated values and experimental results showed that the experimental gain value followed the same pattern of the theoretically calculated value according to the set point change. Also the P-I control using the adaptive control theory showed shorter control time and smaller deviation value than general P-I control.

저빈도 반복성 경두개 자기자극이 정상인의 시각적 단기 기억에 미치는 영향

오해정,김원,이경욱,박원명,전태연,한진희,채정호 大韓神經精神醫學會 2004 신경정신의학 Vol.43 No.5

Objectives : Repetitive transcranial magnetic stimulation (rTMS) is a novel, noninvasive method of brain stimulation. Since conventional rTMS does not cause seizure, marked advantage over electroconvulsive therapy (ECT), rTMS can be used easily and widely. Once the effects of rTMS on cognitive function are elucidated, its application will be further extended. However, the effects of rTMS on cognitive function have not been well examined. This study aimed to evaluate the effect of low frequencyr TMS on visual short term memory. Methods : Forty normal healthy volunteers were randomly assigned to rTMS (n=20) or sham (n=20) groups. The rTMS group were again randomly divided into left prefrontal (n=10) and right prefrontal (n=10) groups. For each group rTMS was given at 1 Hz for 20 minutes with 100% of motor threshold. As a cognitive task, Corsi Block Tapping Test (CORSI) in the computerized Vienna Test System, which can assess visual short term memory, was performed before, during, and after the rTMS. Results : No significant difference was found in the visual short term memories between the rTMS and the sham groups before, during, or after 1 Hz rTMS, nor between the left and right prefrontal rTMS groups. Conclusion : This study demonstrates that rTMS, contrary to ECT, has no adverse visual short term memory effect when used as the standard treatment paradigm. Therefore, rTMS could be a new and safe treatment method in various neuropsychiathc fields without any interference of cognitive function.

3 차 의료기관을 내원한 서부 경남지역의 표재성 피부 진균증 환자에 대한 임상적 및 균학적 인구학적 특성별 분포

오지원,김갑형,김태홍 대한보건협회 1998 대한보건연구 Vol.24 No.1

저자들은 1994년 6월부터 1995년 5월까지 1년간 본원 피부과에 내원하여 표재성 피부 진균증으로 진단 받은 환자 295명에 대한 임상적 및 균학적 관찰을 시행하였으며, 그들의 인구학적 특성별 분포에 대해서 살펴보았다. 결과는 다음과 같다.: 1. 표재성 피부 진균증의 환자는 총 3356명의 신환자중 295명으로 8.8%를 차지하였다. 남녀별 발생빈도는 1.17 : 1로 남자에서 더 많이 발생하였고, 연령별 분포는 30대가 21.7%로 가장 많았으며, 20대에서 50대가 전체의 72.6%를 차지하였다 계절별 분포는 여름이 44.4%, 가을이 22.7%, 봄이 18.0%, 겨울이 14.9%로 주로 여름철에 발생하였다. 2. 병형별 분포는 조갑진균증이 52.2%로 가장 높았으며, 다음으로 족부백선(20.3%), 체부백선(8.5%), 완선(7.1%) 순이었다. 병형별 계절별 분포는 족부백선, 완선, 조갑진균증의 경우 모두 여름철에서 최고치를 보였다. 병형별 연령 분포에서는 조갑진균증은 30대에서 족부백선은 50대에서 높은 분포를 보였다. 병형별 지역 분포는 조갑진균증의 경우 진양군에서, 족부백선의 경우 진주시에서 다른 질환에 비해 높은 비율로 발생하였으며, 직업분포는 조갑진균증의 경우 농부, 족부백선의 경우 가사를 담당하는 환자에서 높은 비율로 나타났다. 병형별 유병기간 분포는 1년이상 10년 이하의 기간에서 조갑진균증이, 1달 이하의 기간에서는 안면백선과 두부백선이 상대적으로 높은 비율을 보였다. 3. 중복 감염은 100명(33.9%)에서 관찰할 수 있었으며, 이중 조갑진균증과 족부백선의 중복 감염이 가장 많았다. 4. KOH 검사상 양성율은 88.5%였으며, 균주의 배양 양성율은 41.7%였다. 원인 균주의 발생 분포는 Trichophyton rubrum이 45.5%로 가장 많았으며, Yeast가 37.4%(Candida albicans; 7.3%), T. mentagrophytes가 13.0%, Microsporum canis가 4.1%였다. We performed clinical, mycologic and epidemiologic studies on 295 cases of dermatomycosis in Department of Dermatology of Gyeongsang National University Hospital from June 1994 to May 1995. The results are summarized as follows : 1. The incidence of dermatomycosis was 8.8% of total out-patients. The ratio of male to female was 1.17 : 1. The incidence rate was highest in the fourth decade(21.7%). The seasonal prevalence was high in summer(44.4%), and then followed by autumn(22.7%), spring(18.0%), and winter(14.9%) in decreasing frequency. 2. The incidence of dermatomycosis in order of frequency were onychomycosis(52.2%), tinea pedis(20.3%), tinea corporis(8.5%), and tinea cruris(7.1%). Relative high frequency of tinea pedis, tinea cruris, onychomycosis was seen in summer. Onychomycosis was relative frequent in the fourth decade and tinea pedis in the sixth decade. Relative high frequency of onychomycosis was seen in patients from Chin-yang gun and tinea pedis in patients from Chin-ju si. Onychomycosis was relatively frequent in farmers and tinea pedis was relatively frequent in housewives. Most patients with onychomycosis showed long duration, and tinea faciei and tinea capitis showed relatively short duration. 3. Coexisting fungal infections were found in 100 patients(33.9%), and onychomycosis with tinea pedis was most common. 4. The positive rate for KOH mount examination was 88.5%, and the positive rate of culture on the Sabouraud's dextrose agar media was 41.7%. Trichophyton rubrum was the most common causative organism of dermatomycosis(45.5%), and then followed by Yeast(37.4%, Candida albican; 7.3%), T. mentagrophytes(13.0%), and M. conis(4.1%) in decreasing frequency.

유도전동기 속도제어를 위한 비선형 비례적분 제어기 설계

오태석,김일환,박찬원 강원대학교 산업기술연구소 2006 産業技術硏究 Vol.26 No.B

This paper presents a robust speed control method of induction motors(IM) using a Non-linear PI controller(NPI). NPI is high gain controller in region of small error, and low gain controller in region of large error. So in steady state, system will be robust against variation of load torque. The simulation and experiment results confirm the validity of proposed control scheme.