동진강 유역내 하천의 특성별 영향평가

윤순강,김원일,김진호,김선종,고문환,엄기철 한국환경농학회 2002 한국환경농학회지 Vol.21 No.4

본 연구는 동진강 유역의 수질 보전을 위한 기초자료를 얻기 위하여 동진강 본류와 이에 유입되는 정읍천을 대상으로 2001년 5월부터 11월까지 수질 모니터링을 실시하였다. 동진강 본류의 수질은 BOD기준으로 상수원 Ⅱ~Ⅳ등급(2.84~6.45 ㎎/L)으로 지점별로는 DJ6(정읍천 합류후)이 4.07㎎/L로 높게 나타나 Ⅲ급수의 수질을 유지하였다. COD는 지점별로 11.20~32.96 ㎎/L의 범위로 정읍천 합류후의 농도가 32.96 ㎎/L로 가장 높게 나타나 정읍천을 통한 본류의 오염물질량의 증가를 알 수 있었다. T-N의 경우 4.16~5.84 ㎎/L의 범위로 유역 전반에 걸쳐 오염이 이루어지고 있는 것으로 나타났고, T-P의 경우 BOD, COD와 마찬가지로 정읍천 합류후가 0.19 ㎎/L로 타 지점에 비하여 놀게 조사되었다. 본류의 COD의 경우 장마후 갈수기에 높은 농도를 나타냈고, T-P의 경우는 하천의 유량이 증가하는 홍수기보다 장마전 갈수기의 오염정도가 높고 이후 장마후 갈수기로 갈수록 수질이 악화되는 것으로 조사되었다. 동진강 수질의 오염은 주로 하류로 갈수록 그 정도가 심하게 나타나는데, 이것은 정읍천을 통해 유입되는 도시 생활하수와 인근 공장단지의 산업폐수가 그 주 요인으로 오염물질(BOD, COD T-N 및 T-P)의 농도가 상승하는 주원인이 되고 있다. 따라서, 동진강 수계의 수질관리를 위해 주 오염원이 되고 있는 정읍천의 도시생활하수와 공장단지에서 방류되는 산업폐수의 제어에 대한 대책이 먼저 이루어져야 할 것으로 판단된다. Irrigation water quality along Donjin river watershed was monitored to find a possible pollutants, for maintaining water quality to achieve food safety through water quality preservation of river. As a pollution indicators, such as Biological Oxygen Demand(BOD), Chemical Oxygen Demand(COD), Total Nitrogen(T-N), and Total Phosphate(T-P) in Dongjin river were examined from May to November in 2001. The results were as follows : The BOD level of Dongji n river ranged from 2.84 to 6.45 mg/L, which would be in a Ⅱ~Ⅳ grade of the potable water criteria by Ministry of Environment. Averaged BOD level of downstream DJ6(After Jeongupcheon confluence) was 4.07 mg/L. The average COD level of Dongjin river ranged from 11.20 to 32.96 mg/L. COD level of DJ6 rapidly increased rapidly after the junction of Dongjin river and Jungupcheon because it showed the latter had relatively high pollution level. T-N content were significantly high in all sites of Dongjin river ranged through 4.16 to 5.84 mg/L. T-P examined high concentration than another thing point by 0.19 mg/L after Jeongupcheon confluence as BOD and COD. COD of main stream was expressed high concentration to dry season after rainy season. In case of T-P, pollution degree of dry season before rainy season appeared and examined that quality of water was worsened go by dry season after rainy season. The water quality of Dongjin river was deteriorated with inflow of Jungupcheon polluted by municipal and industrial sites near Jungup city.

요추부 후방 골유합술시 제4요추 분절동맥의 손상에 의해 발생된 후복막하 혈종의 코일 색전술 치험 1례

이방훈,염진영,최승원,김선환,고현송 대한척추신경외과학회 2004 Neurospine Vol.1 No.1

In spine sugery, iatrogenic vascular injury is unusual, and most common vascular injury is said to be a tear of the left common iliac artery. We report a case of retroperitoneal hematoma from lumbar segmental artery injury after posterior lumbar fusion and pedicle screw fixation. This 60-year-old woman presented with 6 months history of low back pain and radiating pain to the left lower leg. She complained of claudication after 10 meters walking due to spondylolisthesis and spinal stenosis at L2-L5 level. She underwent multiple total laminectomy, posterior lumbar inter-body fusion, and transpedicular screw at L2-L5. During operation there was not evidence of complications such as bleeding. She complained of abdominal pain on post-operation I day and showed tenderness on left upper quadrant. Hemoglobin was 8.4 g/dL on postoperative laboratory examination. Abdominal CT scan revealed retroperitoneal hematoma. We performed angiography for evaluation of hematoma and found extravasation of dye at segmental artery of L4 level. We embolized the bleeding artery with coil successfully. Her postoperative abdominal pain and tenderness were relieved after then and discharged without pain or neurological deficit.

Symposium 3-2-4 (SYP 3-2-4) : A migrating bruise-like plaque on right eyebrow in a 4-year-old boy

( Won Seon Koh ),( Su Jin Oh ),( Hyung Il Kwon ),( Jeong Eun Kim ),( Young Suck Ro ),고주연 ( Joo Yeon Ko ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

A 4-year-old boy presented with a migrating bruise-like erythematous plaque on the medial side of the right eyebrow. His parents reported that the plaque started to appear 6 months ago on the lateral side of right eyebrow after blunt trauma and interestingly migrated from the lateral to medial side of right eyebrow. On skin examination, an erythematous plaque with bluish borer was observed on the right glabella area. The plaque was 1.5 x 1.5 cm in size and firm to palpation. He also had localized painful erythematous swelling on right thigh after contusion a day ago. Skin biopsy from the plaque and additional orthopedic examinations were performed. Hematoxylin-eosin stained section from the plaque showed dense mononuclear cell infiltration throughout the entire dermis. Immunohistochemically, the infiltrated cells were strongly positive for CD10 and CD20, but faintly positive for terminal deoxynucleotidyl transferase(TdT) and negative for CD3 and CD5. The similar cellular infiltration was observed in the specimens from the curettage of distal femur bone. What is your diagnosis?

Erbium-doped Yttrium Aluminum Garnet Laser to Treat Familial Acanthosis Nigricans

( Won Seon Koh ),( Hyung Kwon Park ),( Ho Song Kang ),( Joung Soo Kim ) 대한피부과학회 2018 대한피부과학회지 Vol.56 No.10

[P051] Nail involvement of lichen striatus successfully treated with intralesional steroid injection

( Won Seon Koh ),( Dong Uk Cheon ),( Su Jin Oh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Lichen striatus (LS) is a rare inflammatory dermatosis, characterized by linear papules, mainly along the Blaschko lines of limbs in children. Nail involvement of LS occurs in about 2.6% of patients. Despite various treatment modalities for nail involvement in LS, the efficacies are controversial. Cases treated with intralesional injection (ILI) of steroid have been rarely reported. A 15-year-old boy presented with linear erythematous papules and plaques on left lower leg which has been for 1 month. A biopsy specimen showed lymphocytic infiltration in the upper dermis with epidermal changes including irregular acanthosis and exocytosis of lymphocyte. Based on these findings, he was diagnosed with LS. After 12 weeks of treatment with topical steroid and tacrolimus, the skin lesion was dramatically improved. However, onychodystrophy newly developed at left great toenail (TN) and was getting worse despite of maintenance of treatment with topical tacrolimus. We began to treat his TN with ILI of triamcinolone acetonide (TA) 2.5mg/ml with 2 weeks interval. After 2 months of treatment, clear TN was noted at the proximal portion of TN and almost complete recovery of nail lesion was achieved at 6 months. Herein, we report a case of nail involvement in LS successfully treated with ILI of TA and propose that active treatment could be an effective therapeutic option for nail LS.

[P342] Recurrence of mammary Paget`s disease after radical mastectomy

( Won Seon Koh ),( Dong Uk Cheon ),( Eui Hyun Oh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Mammary Paget`s disease (MPD) is a rare intraepithelial adenocarcinoma. Although the etiology of MPD remains controversial, epidermotropic theory that suggests ductal cancer cells migrate along the basal membrane of the nipple are the origin of Paget`s cells is generally accepted. According to literatures, MPDs as a local recurrence after breast conservative surgery or nipple sparing mastectomy for breast cancer have been reported, but there is no case of MPD that develops after radical mastectomy due to breast cancer. A 69-year-old woman presented with solitary erythematous scaly plaque with stinging on the radical mastectomy scar of left chest. The lesion developed 1 month ago and gradually increased in size. About 16 months ago, she received radical mastectomy for treatment of ductal carcinoma in situ with MPD. In radiologic study, there was no significant finding. With a suspicion of local recurrence, we excised the plaque lesion with about 1 cm margin. Histologic examination showed randomly dispersed Paget`s cells throughout the epidermis without evidence of underlying breast cancer. Based on these findings, the diagnosis of MPD recurrence after radical mastectomy was made. To the best of our knowledge, a case of MPD that develop as local recurrence after radical mastectomy has not been reported. Herein, we report a first case of MPD after radical mastectomy that may raise a point for discussion in the pathogenesis of MPD.

[P125] Two cases of pachydermodactyly treated by intralesional steroid injection

( Won Seon Koh ),( Dong Uk Cheon ),( Eui Hyun Oh ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2017 대한피부과학회 학술발표대회집 Vol.69 No.1

Pachydermodactyly (PDD) is a rare digital fibromatosis characterized by asymptomatic, bulbous swellings on the back and side of the proximal phalanges or proximal interphalangeal (PIP) joint of fingers without any fundamental damage to the joint structures. This condition mostly occurs in adolescent males. Although the etiology of PDD is unknown, the possibility of repetitive minor trauma has been suggested as a cause by several dermatologists. We experienced two cases of PDD that were diagnosed by the clinical, histopathologic, and radiological findings and improved by intralesional injection (ILI) of steroids. A 15-year-old boy and 19-year-old girl presented with asymptomatic, symmetrical swelling of fingers, especially around proximal phalanges and PIP joints which have lasted for 2 and 5 years, respectively. MRI scan of the hands revealed only soft tissue swelling without structural joint abnormality. All laboratory results were within normal range. Histopathologic examination from indurated areas of their fingers revealed thickening of the dermis with haphazardly arranged thick collagen fibers, and small deposits of mucin. The patients were diagnosed with PDD, and treated with ILI of triamcinolone (TA). The lesions remarkably improved without significant adverse effect. Herein, we report two educational cases of PDD which showed clinical improvement with ILI of TA.

Characteristics and Management of Cyclosporine-associated Adverse Gastrointestinal Events

( Won Seon Koh ),( Young Wook Ko ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2019 大韓皮膚科學會誌 Vol.57 No.10

Background: Cyclosporine (CS) is widely used to treat various skin diseases. Gastrointestinal (GI) discomfort is the most common adverse effect of orally administered CS for dermatologic indications. However, few studies on CSassociated adverse GI events have been conducted. Objective: In this study, we aimed to describe the major features of adverse GI events associated with CS therapy using a validated symptom questionnaire, and to investigate the factors contributing to their development. We also evaluated the effectiveness of three empirical GI medications in relieving adverse GI events. Methods: This study consisted of 2 phases. Phase I was a prospective observational cohort study to investigate the characteristics of CS-associated adverse GI events in 942 consecutive patients treated with CS. Phase II was a randomized controlled trial to evaluate the efficacy of three different classes of GI medications. Results: CS-associated adverse GI events occurred in 119 patients (12.6%). GI complications were more common in female patients (p=0.04), patients with a history of GI disorders (p=0.02), and patients whose initial CS doses were greater than 3 mg/kg/day (p=0.05). In patients treated with any one of the three GI medications, the mean Gastrointestinal Symptom Rating Scale scores significantly decreased (p<0.001). Conclusion: This study demonstrated that adverse GI events are common during early CS treatment, especially in women, patients receiving high doses of CS, and those with a history of GI disorders. Our results suggest that new-onset CS-associated GI side effects can be effectively managed with the addition of GI medications. (Korean J Dermatol 2019;57(10):608∼616)

Treatment of sebaceous hyperplasia with a novel 1,927-nm diode laser

( Won Seon Koh ),( Su Jin Oh ),( Hyoung Il Kwon ),( Eun Jin Kim ),( Jeong Eun Kim ),( Joo Yeon Ko ),( Young Suck Ro ) 대한피부과학회 2016 대한피부과학회 학술발표대회집 Vol.68 No.1

Sebaceous hyperplasia is a common benign proliferation of sebaceous glands, characterized by yellow or flesh-toned papules with central umbilication. Various methods using CO2 lasers, electrodesiccation, curettage, and acid destruction have been used for the treatment of sebaceous hyperplasia. However, most techniques destruct nonspecific targets and have risk of complications such as scar formation and dyspigmentation. A novel 1,927-nm diode laser (XLENDER^{®} laser, Won Tech., Daejeon, Korea) was recently introduced for the benefits from relatively selective fat and water absorption than previous devices. We report two patients with sebaceous hyperplasia who were treated with the 1,927-nm diode laser. With one session of treatment, skin lesions nearly disappeared. No significant adverse effect including postinflammatory dyspigmentation or scar formation was noted and relapse has not been observed for the follow-up periods of up to 12months. It is assumed that selective heat damage of the sebaceous gland with sparing of the surrounding tissue achieved by the novel 1,927-nm diode laser device produced excellent cosmetic outcome with minimal adverse effects. Herein, we propose this novel 1,927-nm diode laser could be one of the promising options in the treatment of sebaceous hyperplasia.

Peroxisome Proliferator-Activated Receptor-γ Coactivator 1-α Overexpression Prevents Endothelial Apoptosis by Increasing ATP/ADP Translocase Activity

Won, Jong Chul,Park, Joong-Yeol,Kim, Yun Mi,Koh, Eun Hee,Seol, Somi,Jeon, Byeong Hwan,Han, Jin,Kim, Jung Ran,Park, Tae-Sik,Choi, Cheol Soo,Lee, Woo Je,Kim, Min-Seon,Lee, In-Kyu,Youn, Jang Hyun,Lee, Ki Ovid Technologies Wolters Kluwer -American Heart A 2010 Arteriosclerosis, thrombosis, and vascular biology Vol.30 No.2