Hierarchical reinforcement learning from competitive self-play for dual-aircraft formation air combat

Kong Wei-ren,Zhou De-yun,Zhou Ying,Zhao Yi-yang 한국CDE학회 2023 Journal of computational design and engineering Vol.10 No.2

The recent development of technology helps in the revolutionary war and it controls the war which is influenced by brilliant planning. The maneuver aircraft of intelligent algorithm aids the pilot to decide the particular position on the battlefield. Nowadays the hardware components of radar and missiles are widely used and the beyond visual range is the most popular method applied in air combat. The introduction of close-range air combat maneuver decisions generates the attention of researchers in artificial intelligence. Most of the existing methods are based on autonomous aircraft focused in air combat scenario but manual air combats are widely applied in dual aircraft. Based on the factors mentioned above, a novel hierarchical maneuver decision architecture is applied to a dual-aircraft close-range air combat scenario. Subsequently, the soft actor-critic algorithm is merged with competitive self-play which integrates the knowledge of sub-strategies. Further, the reinforcement learning technique is employed to achieve an approximate Nash equilibrium master strategy. The experimental results show that the hierarchical architecture exhibits good performance, symmetry, and robustness. The research generates a solution for intelligent formation of air combat in the future and guidance for manned or unmanned aircraft cooperative combat.

Modification of Fe/Cu Multilayers under 2-MeV Xe20+ Irradiation

Kong-Fang Wei,Zhi-Guang Wang,Jie Gou,Yan-Bin Sheng,Gen-Ming Jin,Hang Zang,Cun-Feng Yao,Yi-Zhun Ma,Tie-Long Shen 한국물리학회 2009 THE JOURNAL OF THE KOREAN PHYSICAL SOCIETY Vol.55 No.6

Multilayers with a structure of Si/[Fe(10 nm)/Cu(10 nm)]5 were deposited on Si(100) substrates and then irradiated at room temperature by using 2-MeV Xe20+. The modifications of the multilayers were characterized using a depth profile analysis of the Auger electron spectroscopy (AES) data and the evolution of crystallite structures of the multilayers were analyzed by using X-ray diffraction (XRD). The AES depth profiles indicated that de-mixing of the Fe and the Cu layers was observed at low ion fluences, but inter-mixing of the Fe and the Cu layers was found at high ion fluences and destroyed the layered structure of the multilayers. The obtained XRD patterns showed that, after irradiation by 2-MeV Xe20+ at 2 × 1016 ions/cm2, the peaks of the multilayers related to a Cu-based fcc solid solution and an Fe-based bcc solid solution phase became visible, which implied that the inter-mixing at the Fe/Cu interface resulted in the formation of new phases. A possible mechanism of modification in the Fe/Cu multilayers induced by ion irradiation is briefly discussed. Multilayers with a structure of Si/[Fe(10 nm)/Cu(10 nm)]5 were deposited on Si(100) substrates and then irradiated at room temperature by using 2-MeV Xe20+. The modifications of the multilayers were characterized using a depth profile analysis of the Auger electron spectroscopy (AES) data and the evolution of crystallite structures of the multilayers were analyzed by using X-ray diffraction (XRD). The AES depth profiles indicated that de-mixing of the Fe and the Cu layers was observed at low ion fluences, but inter-mixing of the Fe and the Cu layers was found at high ion fluences and destroyed the layered structure of the multilayers. The obtained XRD patterns showed that, after irradiation by 2-MeV Xe20+ at 2 × 1016 ions/cm2, the peaks of the multilayers related to a Cu-based fcc solid solution and an Fe-based bcc solid solution phase became visible, which implied that the inter-mixing at the Fe/Cu interface resulted in the formation of new phases. A possible mechanism of modification in the Fe/Cu multilayers induced by ion irradiation is briefly discussed.

Impact of Low Versus Conventional Doses of Chemotherapy During Transcatheter Arterial Chemo-embolization on Serum Fibrosis Indicators and Survival of Liver Cancer Patients

Kong, Wei-Dong,Cao, Jian-Ming,Xu, Jian,Chen, Bo,Yang, Tao,Xu, Tan-Tan,Lu, Guang-Ming,Li, Jun,Huang, Xin-En Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.9

Objectives: To explore the impact of low- vs conventional-dose chemotherapy via transcatheter arterial chemo-embolization (TACE) on serum fibrosis indicators and treatment efficacy of hepatocellular cancer patients (HCC). Materials and Methods: Patients fulfilling the eligibility criteria were assigned to TACE in Group A (with low-dose chemotherapy) or Group B (conventional-dose chemotherapy). Four serum fibrosis related indicators, hyaluronic acid(HA), human pro-collagen type-III (hPC-III), laminin (LN), and collagen type-IV(IV-C) before TACE were compared with the values 7 days after TACE. The response rate and survival time were also compared between the two groups. Results: Fifty patients with HCC were enrolled in this study, including 25 in Group A and 25 in Group B. No significant differences were detected between the two groups in the four indicators before TACE. After TACE, the value of the four serum indicators increased significantly in Group B. However, no significant differences regarding these four indicators were found in Group A after TACE. Significant differences were demonstrated between the two groups after TACE, but median survival time and 1 or 2 year overall survival rates did not differ (P>0.05). Conclusions: Low-, compared with conventional-dose chemotherapy exerts the same impact on the variation of fibrosis related indicators and has no influence on median survival time and survival rate after TACE in HCC patients.

Effects of the Physical and the Chemical Characters of Soil on Ginseng Quality and Yield

Chang, Wei-Chun,Zha, Libo,Cao, Xiuying,Zhang, Lianxue,Kong, Xiangyi,Zhao, Shoujing,You, Wei The Korean Society of Ginseng 1992 Journal of Ginseng Research Vol.16 No.3

고속주행 교행 차량의 공기역학적 주행특성에 관한 수치해석 연구

공위거(Wei Ju Kong),하양(Yang He),김철호(Chul-Ho Kim) 한국전산유체공학회 2021 한국전산유체공학회지 Vol.26 No.3

For this study, air resistance coefficient (CD), lift coefficient (CL) according to changes in inter-vehicle distance, driving speed, and inter-vehicle separation distance of crossing vehicles, and yawing moment and rolling moment affecting the driving stability of vehicles was calculated and the driving stability of the relative movement vehicle was judged based on the result. According to the results, the lower the vehicle speed, the greater the lateral distance between the two vehicles, and the more stable the vehicle.

중국 애니메이션과 모범극의 상관관계 연구

공덕외(Kong De Wei) 한국만화애니메이션학회 2015 만화애니메이션연구 Vol.- No.39

중국 애니메이션의 역사에서 문화대혁명은 초기 애니메이션의 발전을 저해하고 이후 중국 애니메이션의 성장이 저조해지는 데 원인을 제공한 계기로서 부정적으로 평가된다. 따라서 이 시기 애니메이션 작품들은 학술 연구의 대상으로 분석되거나 연구되는 일이 거의 없이 일률적으로 평가절하되었다. 그러나 모든 문화예술의 창작은 특정한 역사적 조건 속에서 발전하며 그 나름의 미학적 성과를 지닌다. 본고는 문화대혁명 시기의 문화예술 창작을 주도했던 미학 원칙들을 고찰하고 해당 시기의 중국 애니메이션이 거둔 성과를 객관적인 관점에서 파악하려는 데 일차적인 목적을 둔다. 문화대혁명은 무산계급의 문화를 부각시킨다는 마오쩌둥의 사회주의 이데올로기에 따라 이전 시기까지의 문화예술을 지양하고 새로운 계급 문화를 창조하는 데 목적을 두었다. 따라서 이 시기의 문화예술 창작은 우리가 일반적으로 수용하는 미학 원칙과 어긋나는 부분이 많으며 비문자적이고 반엘리트적인 특성을 지닌다. 모범극은 문화대혁명 시기 문화예술의 미학 원칙을 모범적으로 구현한 창작물로 손꼽히며 문화대혁명 시기의 중국 애니메이션이 지향했던 미학 원칙들을 이해하는 데 참조가 된다. 본고는 삼돌출(三突出), 홍광량(紅光亮), 고대전(高大全)이라는 문화대혁명 시기의 미학 원칙이 구체적인 작품 속에서 어떻게 반영되고 있는지, 문화대혁명 시기 애니메이션은 이러한 미학 원칙을 어떻게 수용하고 나름의 방식으로 적응했는지 확인하기 위해 모범극과 문화대혁명 시기 중국 애니메이션의 상관관계에 대해 비교 연구하는 데 중점을 두었다. 먼저 모범극과 중국 애니메이션의 유사성을 중심으로 문화대혁명 시기의 미학 원칙이 작품 속에서 어떻게 구현되고 있는지 분석한 뒤, 분석 내용에 따라 이러한 미학 원칙이 중국 애니메이션의 창작에 끼친 긍정적인 영향과 부정적인 영향을 중립적으로 서술하였다. 구체적인 분석과 비교 고찰 과정에서는 크게 캐릭터와 장면 연출의 두 가지 측면에서 접근을 시도하였다. 캐릭터의 측면에서 문화대혁명 시기의 중국 애니메이션은 어린 소년, 소녀를 주인공으로 내세워 바람직한 공농병(工農兵) 형상을 부각시키기 위해 붉은 입술과 홍조를 띤 뺨을 강조해 건 강함을 강조하고, 매끈한 질감과 정교한 터치로 반짝이는 느낌을 강조하며, 깔끔하고 선명한 색채로 빛나는 색감을 강조하는 ‘홍광량’의 원칙을 구현하는 데 치중하였음을 확인할 수 있었다. 장면 연출의 측면에서 문화대혁명 시기의 애니메이션은 소수의 안타고니스트에 비해 다수의 프로타고니스트를 강조하고, 다수의 프로타고니스트 가운데서도 뛰어난 영웅 인물들을 강조하며, 또 뛰어난 영웅 인물들 가운데서도 주요한 영웅 인물을 강조하는 ‘삼돌출’의 단계별 연출 방식을 사용하였다. 또한 영웅 인물은 일반적으로 로우앵글로 찍음으로써 높고 크고 완벽한 모습으로 연출해 ‘고대전’의 미학 원칙을 충실히 구현하고자 하였다. The Cultural Revolution in the history of Chinese animation hinder the development of the initial animation, and after a negative assessment instrument provided the cause is to become sluggish growth of the Chinese animation. So this time animation are things that are the subject of academic research studies or analysis has been depreciating almost uniformly without evaluation. However, of all the cultural and artistic creation it is developing in its own specific historical conditions and has the aesthetic results. This paper puts the primary purpose is to hold in consideration the aesthetic principles that led to cultural and artistic creativity and objective perspective the achievements the Chinese animation of the time period of the Cultural Revolution. Cultural Revolution is avoided to the previous period in accordance with the socialist ideology of Mao Ze-dong(毛澤東) sikindaneun highlight the culture of the proletariat and placed our goal to create a new class culture . Therefore, cultural and artistic creation of this period is often inconsistent with this part of our aesthetic principles generally accepted character has a non- elitist and anti properties. Best drama is a creative one hand as a model to implement the principles of aesthetics, art and culture Cultural Revolution period kkophimyeo reference for understanding the aesthetic principles that animated the Chinese Cultural Revolution period of orientation. This paper has San Tu Chu(三突出), Hong Guang Liang(紅光亮), and Gao Da Quan(高大全) at the time of the Cultural Revolution aesthetic principles are reflected in how the concrete work , the Cultural Revolution when the animation is how to accommodate these aesthetic principles and placed emphasis on comparative studies on best pole and correlation of the Cultural Revolution when the Chinese animation to ensure that adaptation in own way . First, after analyzing whether the aesthetic principles of focusing on the similarities of the best pole time of the Cultural Revolution and China, and how to implement animation in the works , these aesthetic principles according to the analysis of positive and negative influence on the creation of Chinese animation It was described as neutral. The detailed analysis and comparative study courses were trying to access in two significant aspects of the characters and scenes directing. In terms of character animation of the Cultural Revolution in China when a young boy or girl, emphasis should emphasize the health tinged with red lips and cheek blush to highlight the desired Gong Nong Bing(工農兵) shape as the main character and smooth texture and sophisticated highlights the glittering feeling to the touch, it was confirmed focused hayeoteum to implement the principle of ‘Hong Guang Liang’, highlighting the brilliant colors with a clean, bright colors. Highlighting a number of protagoniste compared to the antagonist in the animated scene of the Cultural Revolution a few times in terms of production and, among a number of protagoniste also emphasizes the outstanding hero figure, "yet three outstanding heroes heroic figures also emphasize the leading figures among the the director of the extrusion step-by-step approach "(‘San Tu Chu’)was used. In addition, the hero figure is generally high and low angle by directing a large and perfect aesthetic appearance was to faithfully implement the principle of "high-charged"(‘Gao Da Quan’).

Associations of Single Nucleotide Polymorphisms in miR-146a, miR-196a, miR-149 and miR-499 with Colorectal Cancer Susceptibility

Du, Wei,Ma, Xue-Lei,Zhao, Chong,Liu, Tao,Du, Yu-Liang,Kong, Wei-Qi,Wei, Ben-Ling,Yu, Jia-Yun,Li, Yan-Yan,Huang, Jing-Wen,Li, Zi-Kang,Liu, Lei Asian Pacific Journal of Cancer Prevention 2014 Asian Pacific journal of cancer prevention Vol.15 No.2

Background: MicroRNAs (miRNAs) are an abundant class of endogenous small non-coding RNAs of 20-25 nucleotides in length that function as negative gene regulators. MiRNAs play roles in most biological processes, as well as diverse human diseases including cancer. Recently, many studies investigated the association between SNPs in miR-146a rs2910164, miR-196a2 rs11614913, miR-149 rs229283, miR-499 rs3746444 and colorectal cancer (CRC), which results have been inconclusive. Methodology/Principal Findings: PubMed, EMBASE, CNKI databases were searched with the last search updated on November 5, 2013. For miR-196a2 rs11614913, a significantly decreased risk of CRC development was observed under three genetic models (dominant model: OR = 0.848, 95%CI: 0.735-0.979, P = 0.025; recessive model: OR = 0.838, 95%CI: 0.721-0.974, P = 0.021; homozygous model: OR = 0.754, 95%CI: 0.627-0.907, P = 0.003). In the subgroup analyses, miR-$196a2^*T$ variant was associated with a significantly decreased susceptibility of CRC (allele model: OR = 0.839, 95%CI: 0.749-0.940, P = 0.000; dominant model: OR = 0.770, 95%CI: 0.653-0.980, P = 0.002; recessive model: OR = 0.802, 95%CI: 0.685-0.939, P = 0.006; homozygous model: OR = 0.695, 95%CI: 0.570-0.847, P = 0.000). As for miR-149 rs2292832, the two genetic models (recessive model: OR = 1.199, 95% CI 1.028-1.398, P = 0.021; heterozygous model: OR = 1.226, 95% CI 1.039-1.447, P = 0.013) demonstrated increased susceptibility to CRC. On subgroup analysis, significantly increased susceptibility of CRC was found in the genetic models (recessive model: OR = 1.180, 95% CI 1.008-1.382, P = 0.040; heterozygous model: OR = 1.202, 95% CI 1.013-1.425, P = 0.013) in the Asian group. Conclusions: These findings supported that the miR-196a2 rs11614913 and miR-149 rs2292832 polymorphisms may contribute to susceptibility to CRC.

Cloning of Phospholipase D from Grape Berry and Its Expression under Heat Acclimation

( Si Bao Wan ),( Wei Wang ),( Peng Fei Wen ),( Jian Ye Chen ),( Wei Fu Kong ),( Qiu Hong Pan ),( Ji Cheng Zhan ),( Li Tian ),( Hong Tao Liu ),( Wei Dong Huang ) 생화학분자생물학회 2007 BMB Reports Vol.40 No.4

Cloning of Phospholipase D from Grape Berry and Its Expression under Heat Acclimation

Wan, Si-Bao,Wang, Wei,Wen, Peng-Fei,Chen, Jian-Ye,Kong, Wei-Fu,Pan, Qiu-Hong,Zhan, Ji-Cheng,Tian, Li,Liu, Hong-Tao,Huang, Wei-Dong Korean Society for Biochemistry and Molecular Biol 2007 Journal of biochemistry and molecular biology Vol.40 No.4

To investigate whether phospholipase D (PLD, EC 3.1.4.4) plays a role in adaptive response of post-harvest fruit to environment, a PLD gene was firstly cloned from grape berry (Vitis Vinifera L. cv. Chardonnay) using RT-PCR and 3'- and 5'-RACE. The deduced amino acid sequence (809 residues) showed 84.7% identity with that of PLD from Ricinus communis. The secondary structures of this protein showed the characteristic C2 domain and two active sites of a phospholipid-metabolizing enzyme. The PLD activity and its expression in response to heat acclimation were then assayed. The results indicated PLD was significantly activated at enzyme activity, as well as accumulation of PLD mRNA and synthesis of new PLD protein during the early of heat acclimation, primary suggesting that the grape berry PLD may be involved in the heat response in post-harvest grape berry. This work offers an important basis for further investigating the mechanism of post-harvest fruit adaptation to environmental stresses.

Fluorescence-in-situ-hybridization in the Surveillance of Urothelial Cancers: Can Use of Cystoscopy or Ureteroscopy be Deferred?

Ho, Christopher Chee Kong,Tan, Wei Phin,Pathmanathan, Rajadurai,Tan, Wei Keith,Tan, Hui Meng Asian Pacific Journal of Cancer Prevention 2013 Asian Pacific journal of cancer prevention Vol.14 No.7

Background: Fluorescence in situ hybridization (FISH) testing may be useful to screen for bladder carcinoma or dysplasia by detecting aneuploidy chromosomes 3, 7, 17 and deletion of the chromosome 9p21 locus in urine specimens. This study aimed to assess the sensitivity, specificity, positive and negative predictive value of FISH in a multi-ethnic population in Asia. Materials and Methods: Patients with haematuria and/or past history of urothelial cancer on follow-up had their voided urine tested with FISH. Patients then underwent cystoscopy/ureteroscopy and any lesions seen were biopsied. The histopathological reports of the bladder or ureteroscopic mucosal biopsies were then compared with the FISH test results. Results: Two hundred sixty patients were recruited. The sensitivity and specificity of the FISH test was 89.2% and 83.4% respectively. The positive (PPV) and negative predictive values (NPV) were 47.1% and 97.9%. By excluding patients who had positive deletion of chromosome 9, the overall results of the screening test improved: sensitivity 84.6%; specificity 96.4%; PPV 75.9% and NPV 97.9%. Conclusions: UroVysion FISH has a high specificity of detecting urothelial cancer or dysplasia when deletion of chromosome 9 is excluded. Negative UroVysion FISH-tests may allow us to conserve health resources and minimize trauma by deferring cystoscopic or ureteroscopic examination.