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Kuo-Tai Chen,Sung-Tai Wei,Chun Tseng,Su-Wei Ou,Li-Wei Sun,Chien-Min Chen 대한척추신경외과학회 2020 Neurospine Vol.17 No.sup.
With the trend of minimally invasive spine surgery, full-endoscopic lumbar discectomy (FELD) has evolved with the advancement of the optics and instruments. Regarding the techniques, the transforaminal and interlaminar approach remain the major accesses in FELD. Transforaminal endoscopic lumbar discectomy (TELD) is an effective and safe treatment for herniation of the lumbar disc. More and more evidence supports the TELD in enhancing recovery and decreasing surgical complications. However, the learning curve of TELD remains steep, especially at the L5–S1 level. The iliac crest height is an essential factor in the operability of TELD at the L5–S1 level. In the situation of the high iliac crest, TELD is technically challenging even for an experienced surgeon. Therefore, the authors report their techniques of TELD with foraminoplasty step-by-step and the preliminary results in this report.
Chien-Min Chen,Jae Hwan Lee,Meng-Yin Yang,Shang-Wun Jhang,Kai-Sheng Chang,Su-Wei Ou,Li-Wei Sun,Kuo-Tai Chen 대한척추신경외과학회 2023 Neurospine Vol.20 No.1
Objective: Sacroiliac joint (SIJ) pain is a common cause of chronic low back pain. Full-endoscopic rhizotomy of lateral branches of dorsal rami innervating SIJ is a potential option for patients’ refractory to medical treatment. The full-endoscopic rhizotomy is sometimes challenging under fluoroscopic guidance. This study is to evaluate the effectiveness of the navigation-assisted full-endoscopic rhizotomy for SIJ pain. Methods: The study was a retrospective match-paired study that enrolled consecutive patients undergoing navigation-assisted full-endoscopic rhizotomy for SIJ pain. The patient demographics, clinical outcomes, and operative parameters of endoscopic rhizotomy were compared with conventional cooled radiofrequency ablation (RFA) treatment. Results: The study enrolled 72 patients, including 36 patients in the endoscopic group. Thirty-six patients in the cooled RFA group were matched by age as the control. The follow-up time was at least 1 year. Patient characteristics were similar between the groups. The navigation-assisted endoscopic rhizotomy operation time was significantly longer than the cooled RFA. The visual analogue scale (VAS) for pain and Oswestry Disability Index (ODI) significantly decreased after each treatment. However, the between-group comparison revealed that the VAS and ODI of the patients after endoscopic rhizotomy were significantly lower than those after the cooled RFA group. There were no postoperative complications in the study. Conclusion: Navigation-assisted full-endoscopic rhizotomy is an alternative to SIJ pain treatment. Integrating intraoperative navigation can ensure accurate full-endoscopic rhizotomy to provide better durability of pain relief than the cooled RFA.
A High-Quality Image Authentication Scheme for AMBTC-compressed Images
( Chia-chen Lin ),( Yuehong Huang ),( Wei-liang Tai ) 한국인터넷정보학회 2014 KSII Transactions on Internet and Information Syst Vol.8 No.12
In this paper, we present a high-quality image authentication scheme based on absolute moment block truncation coding. In the proposed scheme, we use the parity of the bitmap (BM) to generate the authentication code for each compressed image block. Data hiding is used to authenticate whether the content has been altered or not. For image authentication, we embed the authentication code to quantization levels of each image block compressed by absolute moment block truncation coding (AMBTC) which will be altered when the host image is manipulated. The embedding position is generated by a pseudo-random number generator for security concerned. Besides, to improve the detection ability we use a hierarchical structure to ensure the accuracy of tamper localization. A watermarked image can be precisely inspected whether it has been tampered intentionally or incautiously by checking the extracted watermark. Experimental results demonstrated that the proposed scheme achieved high-quality embedded images and good detection accuracy, with stable performance and high expansibility. Performance comparisons with other block-based data hiding schemes are provided to demonstrate the superiority of the proposed scheme.
In Vitro Biological Characterization of DCUN1D5 in DNA Damage Response
Guo, Wei,Li, Guo-Jun,Xu, Hong-Bo,Xie, Jie-Shi,Shi, Tai-Ping,Zhang, Sheng-Zhong,Chen, Xiao-Hong,Huang, Zhi-Gang Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.8
Background: Novel prognostic biomarkers or therapeutic molecular targets for laryngeal squamous cell carcinoma (LSCC) are an urgent priority. We here sought to identify multiple novel LSCC-associated genes. Methods: Using high-density microarray expression profiling, we identified multiple genes that were significantly altered between human LSCCs and paired normal tissues. Potential oncogenic functions of one such gene, DCUN1D5, were further characterized in vitro. Results: Our results demonstrated that DCUN1D5 was highly expressed in LSCCs. Overexpression of DCUN1D5 in vitro resulted in 2.7-fold increased cellular migration, 67.5% increased invasive capacity, and 2.6-fold increased proliferation. Endogenous DCUN1D5 expression was decreased in a time-dependent manner after genotoxic stress, and silencing of DCUN1D5 by siRNA decreased the number of cells in the S phase by 10.2% and increased apoptosis by 11.7%. Conclusion: Our data suggest that DCUN1D5 in vitro might have vital roles in DNA damage response, but further studies are warranted to assess its significance in vivo.
A Study on Fiber Laser Lap Welding of Thin Stainless Steel
Rong-Tai Yang,Zhi-Wei Chen 한국정밀공학회 2013 International Journal of Precision Engineering and Vol. No.
This study analyzed variations of shear strength that depend on the fiber laser process during lap welding of AISI 304 stainless thin sheets. The experimental plan was based on a Taguchi orthogonal array table. A hybrid method that includes the response surface methodology (RSM) and back-propagation neural network (BPNN) integrated genetic algorithm (GA) are proposed to search for an optimal parameter setting of the lap welding process. The results show that the RSM and BPNN/GA methods are both effective tools for the optimization of lap welding process parameters. At the same time, an analysis of variance (ANOVA) was implemented to identify significant factors influencing the lap welding process parameters. In addition, the micrographs also show that the appropriate setting of the laser power, befitting the penetration depth and welding line length of the fusion zone sections were produced. A confirmation experiment was also conducted in order to validate the optimal welding process parameter values.
Cheng-Tai Kuo,Karuppannan Balamurugan,Hung Wei Shiu,Hyun Ju Park,Soobin Sinn,Michael Neumann,한문섭,장영준,Chia-Hao Chen,Hyeong-Do Kim,박제근,Tae Won Noh 한국물리학회 2016 Current Applied Physics Vol.16 No.3
We have studied the electronic structure and interfacial properties of mechanically exfoliated few-layer NiPS3 van der Waals crystals on ZnO/Nb:SrTiO3 substrates using scanning photoelectron microscopy and spectroscopy. The conducting ZnO layer enhances the visibility of few-layer NiPS3 on Nb:SrTiO3 and prevents charging effects in photoemission. We experimentally determined a type-II band alignment at the NiPS3/ZnO interface. The valence band offset (VBO) of few-layer NiPS3/ZnO is 2.8 ± 0.09 eV, and the conduction band offset is 1.0 ± 0.09 eV. Moreover, we found an increase of ~0.3 eV in VBO as decreasing NiPS3 thickness, suggesting electronic coupling or charge transfer at the NiPS3/ZnO interface.
Computation Controllable Mode Decision and Motion Estimation for Scalable Video Coding
Liang-Wei Zheng,Gwo-Long Li,Mei-Juan Chen,Chia-Hung Yeh,Kuang-Han Tai,Jian-Sheng Wu 한국전자통신연구원 2013 ETRI Journal Vol.35 No.3
This paper proposes an efficient computation-aware mode decision and search point (SP) allocation algorithm for spatial and quality scalabilities in Scalable Video Coding. In our proposal, a linear model is derived to allocate the computation for macroblocks in enhancement layers by using the rate distortion costs of the base layer. In addition, an adaptive SP decision algorithm is proposed to decide the number of SPs for motion estimation under the constraint of the allocated computation. Experiment results demonstrate that the proposed algorithm allocates the computation resource efficiently and outperforms other works in rate distortion performance under the same computational availability constraint.
Image Tracking of Laparoscopic Instrument Using Spiking Neural Networks
Chun-Ju Chen,Wayne Shin-Wei Huang,Kai-Tai Song 제어로봇시스템학회 2013 제어로봇시스템학회 국제학술대회 논문집 Vol.2013 No.10
Minimally Invasive Surgery (MIS) has become more and more popular in recent years. An endoscopic image tracking system will assist surgeons to adjust the field of view autonomously in MIS. In this paper, we propose a novel image tracking algorithm based on natural features of surgical instruments. We suggest to use texture and geometric features in laparoscopic instrument imagery and to adopt a spiking neural network approach for object detection; considering color will be affected by lighting and the white balance conditions in the endoscope imagery. To enhance tracking performance, we further design a Kalman filter to combine with the neuro-based tracker. The instrument can be detected more robustly despite of deformation of the instrument image during surgery. A laparoscopic video has been tested to verify the developed methods. Experimental results show that two instruments can be distinguished and tracked simultaneously in the surgical video.
Causal Relations between Exposome and Stroke: A Mendelian Randomization Study
Hong-Qi Li,Yi-Wei Feng,Yu-Xiang Yang,Xin-Yi Leng,Prof Can Zhang,Shi-Dong Chen,Kevin Kuo,Shu-Yi Huang,Xue-Qing Zhang,Yi Dong,Xiang Han,Xin Cheng,Mei Cui,Lan Tan,Qiang Dong,Jin-Tai Yu 대한뇌졸중학회 2022 Journal of stroke Vol.24 No.2
Background and Purpose To explore the causal relationships of elements of the exposome with ischemic stroke and its subtypes at the omics level and to provide evidence for stroke prevention. Methods We conducted a Mendelian randomization study between exposure and any ischemic stroke (AIS) and its subtypes (large-artery atherosclerotic disease [LAD], cardioembolic stroke [CE], and small vessel disease [SVD]). The exposure dataset was the UK Biobank involving 361,194 subjects, and the outcome dataset was the MEGASTROKE consortium including 52,000 participants. Results We found that higher blood pressure (BP) (systolic BP: odds ratio [OR], 1.02; 95% confidence interval [CI], 1.01 to 1.04; diastolic BP: OR, 1.03; 95% CI, 1.01 to 1.05; pulse pressure: OR, 1.03; 95% CI, 1.00 to 1.06), atrial fibrillation (OR, 1.18; 95% CI, 1.13 to 1.25), and diabetes (OR, 1.13; 95% CI, 1.07 to 1.18) were significantly associated with ischemic stroke. Importantly, higher education (OR, 0.69; 95% CI, 0.60 to 0.79) decreased the risk of ischemic stroke. Higher systolic BP (OR, 1.06; 95% CI, 1.02 to 1.10), pulse pressure (OR, 1.08; 95% CI, 1.02 to 1.14), diabetes (OR, 1.28; 95% CI, 1.13 to 1.45), and coronary artery disease (OR, 1.58; 95% CI, 1.25 to 2.00) could cause LAD. Atrial fibrillation could cause CE (OR, 1.90; 95% CI, 1.71 to 2.11). For SVD, higher systolic BP (OR, 1.04; 95% CI, 1.00 to 1.07), diastolic BP (OR, 1.06; 95% CI, 1.01 to 1.12), and diabetes (OR, 1.22; 95% CI, 1.10 to 1.36) were causal factors. Conclusions The study revealed elements of the exposome causally linked to ischemic stroke and its subtypes, including conventional causal risk factors and novel protective factors such as higher education.