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- 저자 : ( Vedat Hamuryudan ) (검색결과 1 건)
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( Yesim Ozguler ),( Vedat Hamuryudan ),( Gulen Hatemi ),( Ayse Selcen Pala ),( Sebahattin Yurdakul ),( Hasan Yazici ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: We surveyed the causes and outcome of hospitalisations among Behcet Syndrome (BS) patients in a dedicated center. Methods: The records of all inpatients in our clinic between 2002-2011 were retrospectively reviewed to identify patients hospitalised with a diagnosis of BS. We reviewed both the inpatient and outpatient charts to identify the demographic and clinical features, causes of hospitalisation and outcome. We also contacted the patients to determine their current condition. Results: 178 BS patients (74% men, mean age 42. 9±11. 3) had been hospitalised for a total of 211 times during the last ten years. We were able to contact 104(58%) of them. The reasons for hospitalisation were directly related to BS organ involvement in 118(56%) and to complications in 93(44%). The most common BS related reasons were vascular involvement in 74/118(63%) (including 21 patients with pulmonary artery aneurysms, 10 with peripheral artery aneurysms and 11 with serious venous thrombosis such as vena cava superior and Budd-Chiari syndrome), neurologic involvement in 14/118(12%), gastrointestinal involvement in 6/118(5%) and eye involvement in 6/118(5%). Hospitalisations caused by complications of BS were infections in 39/93(42%), and other drug related adverse events in 15/93(16%). Neoplasias were diagnosed in 5 patients. Among the 178 patients, 16(9%) had died. Most common causes of death were vascular involvement (n=5), infections (n=4) and malignancies (n=4). Conclusions: Vascular involvement is the leading cause of hospitalisation among BS patients, followed by infections related to therapy. Adverse events related to immunosuppressives are problematic. The predominance of men among hospitalized patients underlines the more severe course of BS in this sex. The relatively low frequency of gastrointestinal involvement among hospitalisations is in line with our previous observation that this type of involvement is rare in our BS patients.
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