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      • KCI등재

        코호트 효과를 고려한 주택연금 수요 추정

        박상수(Sang-Soo Park),심미령(Mi-Ryung Sim),이충기(Chung-Ki Lee) 한국경제연구학회 2017 한국경제연구 Vol.35 No.3

        2007년부터 시행되고 있는 한국의 주택연금제도는 정부가 보증하는 역모기지 프로그램이다. 한국주택금융공사가 매년 실시하고 있는 연간 설문 자료를 이용하여 미래에 주택연금을 이용할 의향이 있는 가구들에 대해 주택연금에 대한 수요를 추정하였다. 본 논문에서는 이충기․박상수(2014)의 연구를 확장하여 미래 기대와 코호트 효과를 고려하여 순서형 로짓 모형을 설정하였다. 설문에서 진술된 가구의 의향이 미래에 대한 기대에 근거하고 있다는 점을 적절하게 평가하기 위해 몇 가지의 가정을 바탕으로 미래의 기대형성 과정을 계량경제학적으로 모형화하여 주택연금 수요를 예측하고자 하였다. 주택연금에 대한 수요 추정 결과에 따르면, 주택연금 프로그램에 대해 후세대들이 보다 덜 긍정적인 경향이 나타난 반면 저소득 계층은 보다 긍정적으로 나타났다. The J ooTaekYeonKeum is the government guaranteed reverse mortgage program that Korean Government has been implementing since 2007. We extended Lee and Park’s(2014) demand estimation for the reverse mortgage loans in Korea using the yearly survey data, conducted by Korea Housing Financing Corporation, for household’s intention to use J ooTaekYeonKeum in the future. In order to appropriately appreciate the fact that the stated intentions in the survey were based on households’ expectations for their future, we adopted an econometric procedure that incorporated expectations explicitly as well as cohort effects. Our findings include: demands for reverse mortgage loans are estimated similar to that of Lee and Park(2014); later generations tend to be less positive for having the reverse mortgage program; lower income groups are more positive for the program.

      • KCI등재

        계피나무의 部位別 抗酸化 作用에 關한 硏究(Ⅰ)

        朴聆俊,朴涌基 대한본초학회 2000 大韓本草學會誌 Vol.15 No.2

        The antioxidation effects of Cinnamomi Cortex (CC), Cinnamomi Ramulus (CR), Cinnamomi Petiole (CP) on the radical scavenging ability from 1,1'-Diphenyl-2-picrylhydrazyl (DPPH), activities of nitrate reductase (NR), superoxide dismutase (SOD), xanthine oxidase and lipid peroxidase (LPO) in rat liver cells were examined. In in vitro studies, CR extract had greater DPPH-radical scavenging ability than CC and CP. The NR acitivity in the cells was more increased by the treatments of CC and CR extracts than CP extract. The enzyme activity of Xanthine oxidase of CC was decreased. Also, levels of lipid peroxidation were proportionally decreased to concentrations of CR. The recovery by CR extract treatment was similar to the level of ascorbic acid treatment. Therefore, it seems that CR extract has similar effects on the antioxidation compared with ascorbic acid, well-known antioxidant. The data indicate that CR has a depressive effect on the production of free radicals and changes in the acitivities of enzymes involved in the antioxidation. Compared to others, CP had smaller effects on the antioxidation. These results suggest that CR seems to have more potent effects on the antioxidation than other parts of Cinamomum cassia and different mechanisms might be involved in the anitoxidation processes of CC, CP, and CR.

      • 惡性腫瘍 治療에 應用되는 藥物에 대한 文獻的 考察

        朴?俊,朴用基 동국대학교 한의학연구소 2000 東國韓醫學硏究所論文集 Vol.9 No.-

        韓藥材의 癌治療에 應用 可能性을 硏究한 23種의 論文을 對象으로 하여 文獻的으로 考察한바, 韓醫學에서는 淸熱解毒, 淸熱解血, 活血化瘀, 理氣補神養血, 化痰軟堅, 健脾化濕, 理氣散結하는 韓藥材를 이용하여 扶王法, 祛邪法, 扶正祛邪法으로써 癌治療에 應用하고 있으며, 實驗에 使用된 약물ms 總103種으로 이 中에서 魚腥草는 癌細胞株에 대한 感受性도 높게 나타났지만 正常細胞에 대한 柳制效果는 낮게 나타났고, 吳茱萸, 木香, 黑丑은 20여종의 癌細胞株에 모두 높은 細胞毒性이 나타났으며, 二白草는 HT-29, melanoma, 나-MEL-5에, 知母는 卵??癌 細胞柱에, 三白草는 HT-29 細胞柱에 특히 높은 活性을 보였다. 또한 實驗에 사용된 癌細胞柱 중에서 생쥐 유래의 P815, Yac-1 細胞柱와 사람의 Sarcoma 180, K562, SNU-1 細胞柱가 가장 多用되었다. This studies were examined in orther to investigate the object and the method of animal experimental papers on medicinal herbs of cancer therapeutic activities from the reported 23 literatures containing anti-cancer effects of medicinal herbs. The results were obtained as follows: 1. The oriental medicinal therapies on cancer were Pujeung(扶王法), Kuesa(祛邪法), Pujeungkuesa(扶正祛邪法). 2. The experimental medicinal herbs of cancers therapy were 103 species, which was used for experimental cancer single or combine. Among then, Houttuyniae herba, Polyporus, Manitis squama, Evodiae fructus, Aucklandiae radix and Pharbitidis semen were effective for cancer treatment, while Houttuyniae herbu inhibited tumor cells, but not normal cells. Also, Euodiae fructus, Auckhdiae radix and Pharbitidis semen showed strong cytoxicities on 20 different tumor cell lines, whereas Saururi herba seu rhizomu showed cytoxicity against HT-29 cell, melanoma, SK-MEL-5 cell, and Anemarrhenue rhizoma against ovarian tumor cell only, and Schizonepetae herba against HT-29 cell line only with a potent inhivitory activities. 3. P815 cell, Yac-1 cell, Sarcoma 180 cell, K 562 cell, and SNU-1 cells were frequently used as experimental cancer therapy.

      • Pd(O)-촉매를 이용한 알릴 고리 카보네이트의 제거 및 분자간 축합반응 연구

        강석구,박동철,박찬희,홍륭기 성균관대학교 기초과학연구소 1995 論文集 Vol.46 No.1

        The alkyl substituted allylic cyclic carbonates 1a-d undergo elimination by using a catalytic amount of Pd(0) complex to form dienols 2 a-b. However, on treatment of the unsubstituted or phenyl substituted allylic cyclic carbonates 1e and 1f with Palladium(0) catalyst, deprotonation-elimination of π-allyl Palladium complex followed by condensation with the other π-allyl Palladium complex provided the coupled products 3a and 3b, respectively.

      • 머리염색이 인체에 미치는 영향

        윤형식,황성호,이현륭,김수호,박연석,권낙현,정호진,김동훈,노현주,홍성호,박병찬,이관,정해관 東國大學校醫學硏究所 2002 東國醫學 Vol.9 No.1

        일상생활에서 모발염색은 흔히 접할 수 있는 미용의 한 종류로 특히 젊은층을 중심으로 폭발적으로 유행하고 있다. 염색을 위항 사용하는 약제는 표백제와 발색제 등 각종 화학약품이 사용되고 있으나 이로 인한 건강장해에 대한 연구는 그리 많지 않다. 저자들은 염색이 인체의 모발건강에 미치는 영향을 파악하기 위하여 염색과 관련된 주관적 증상과 모발의 변화에 대한 실험적 연구를 시행하였다. 동국대학교 경주 캠퍼스 재학생 80명을 대상으로 설문조사를 시행하여 염색 유 ·무 및 염색 후에 경험한 증상에 대해 설문 조사하였고, 의과대학 재학생 46명을 대상으로 피부 반응 테스트를 실시하였다. 또한 염색 전후의 모발 탄성도를 측정하였고 모발의 상태를 파악하기 위해 전자 현미경검사를 실시하였다. 설문조사 결과 염색 전에 비하여 염색 후 안구혼탁, 안구건조, 시력저하, 발진 및 접촉성 피부염, 모발손상, 모근손상 등의 증상을 더 많이 경험한다고 호소하였다(p<0.05). 모발손상과 모근손상은 헤어드라이어 사용 빈도에 따라 증가하는 것으로 조사되었다(p<0.05). 피부반응검사에서 가려움증이 가장 많은 증상이었으며 이는 여성보다는 남성에서 높은 것으로 조사되었다. 염색 전후의 모발장력은 염색 전 134.5±10.37g, 염색 128.0±30.69g, 염색 이틀 후 112.5±19.69g으로 나타났다. 염색 전후의 모발의 전자현미경 케라틴 층이 현저히 감소하고 모발이 가늘어지는 차이를 보였다. 염색은 모발손상, 모발 케라틴 손상 및 모근 손상, 발진 및 접촉성 피부반응, 안구혼탁, 안구건조, 시력 저하를 유발한다. 따라서 염색약으로 인한 손상에 대한 주의와 예방이 필요하다고 생각한다. 예방대책으로 염색 전 피부테스트를 통한 적합성 여부를 판단하는 것이 필요하며 가급적 염색을 피하는 것이 좋을 것이다. 염색약에 발암물질이 포함되어있다는 보고도 있어 염색 제조사의 철저한 실험과 염색 물질의 선별이 염색으로 인한 부작용을 최소화하는데 중요한 역할을 할 것이다. Hair coloring has became one of the most popular cosmetic activities to younger generations during last decade. However, there are few studies on the health effect of widespread use of chemical dyes. This study was conducted to study the effects of hair coloring dye on hair and other systems. We conducted a questionnaire survey of 80 persons in Kyongju campus, Dongguk University. We have done open patch skin test on 46 medical students. We also conducted scanning electron microscopy to examine the hair strength and structure before and after hair coloring process. Injury of hair and hair bulb, contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity were the main symptoms complained after hair coloring (p<0.05). Injury of hair and hair bulb were increased by frequency of hair-dryer use(p<0.05). In open patch test, pruritus was complanined by more than half of the subjects. Mean strength of hairs before and after hair coloring was as follows; 134.5 (SD 10.37)g before hair coloring, 128.0 (SD 30.69)g immediately after hair coloring, and 112.5 (SD 19.69)g after two days. The scanning electron microscopic findings of hair surface before and after hair coloring showed decreased keratin layer and thinning of the hair. Hair coloring induces injury to hair, its keratin layer, and hair bulb as well as contact dermatitis, turbid eyes, xerophthalmia, and poor visual acuity. Therefore, we think that precaution is needed in use of hair coloring dye. To prevent complications induced by hair coloring dye, it is necessary, especially to those with allergy or skin disorders, to perform skin test before action and avoid hair coloring whenever possible. Longterm health effects of hairdye should be studied and manufacturing companies should try to minimize complications induced by hair coloring dye.

      • Depletion of <small>L</small>-ascorbic acid alternating with its supplementation in the treatment of patients with acute myeloid leukemia or myelodysplastic syndromes

        Park, Chan H.,Kimler, Bruce F.,Yi, Seong Yoon,Park, Se Hoon,Kim, Kihyun,Jung, Chul Won,Kim, Sun Hee,Lee, Eun Ryung,Rha, Miyong,Kim, Seonwoo,Park, Mary H.,Lee, Sook J.,Park, Hye K.,Lee, Mark H.,Yoon, S Blackwell Publishing Ltd 2009 European journal of haematology Vol.83 No.2

        <P>Abstract</P><P>Purpose: </P><P><SMALL>L</SMALL>-ascorbic acid (LAA) modifies the <I>in vitro</I> growth of leukemic cells from ∼50% of patients with acute myeloid leukemia (AML) or myelodysplastic syndromes (MDS). To test the hypothesis that depletion of LAA, alternating with supplementation to prevent scurvy, would provide therapeutic benefit, a single-arm pilot trial was conducted (ClinicalTrials.gov identifier: NCT00329498).</P><P>Experimental results: </P><P>During depletion phase, patients with refractory AML or MDS were placed on a diet deficient in LAA; during supplementation phase, patients received daily intravenous administration of LAA. An <I>in vitro</I> assay was performed pretherapy for LAA sensitivity of leukemic cells from individual patients.</P><P>Results: </P><P>Of 18 patients enrolled, eight of 16 evaluable patients demonstrated a clinical response. Responses were obtained during depletion (four patients) as well as during supplementation (five patients) but at a pharmacologic plasma level achievable only with intravenous administration. Of nine patients for whom the <I>in vitro</I> assay indicated their leukemic cells were sensitive to LAA, seven exhibited a clinical response; compared with none of six patients who were insensitive to LAA.</P><P>Conclusions: </P><P>The clinical benefit, along with a conspicuous absence of significant adverse events, suggests that further testing of LAA depletion alternating with pharmacologic dose intravenous supplementation in patients with these and other malignancies is warranted.</P>

      • KCI등재
      • 조혈모세포이식 환자의 이식단계별 수면장애 영향요인

        박혜령(Park Hae-Ryung),최소은(Choi So-Eun),박호란(Park Ho-Ran),박진희(Park Jin-Hee),문영임(Moon Young-Im) 대한종양간호학회 2005 Asian Oncology Nursing Vol.5 No.2

        Purpose: The present study was to investigate sleep disturbance and related variables in patients undergoing hemopoietic stem cell transplantation(HSCT) on the day of admission, before HSCT, and of discharge, respectively. Method: A total of 52 HSCT patients were recruited from an university hospital from August 2002 to August 2003. The patients were asked to complete a set of sleep disturbance questionnaires. Result: The scores of sleep disturbance-related physical and emotional subscales on the day before HSCT and on the day of discharge were significantly higher than that on the day of admission. However, the score of a emotional subscale was not significantly different during the hospitalization for HSCT. About 10% of the variance of sleep disturbance was explained by the length after diagnosis on the day of admission, and 59.4% was by the type of disease, religion, gender, educational level on the day before HSCT. About 40.7% was by family income, gender, and the frequency of administration on the day of discharge. Conclusion: Nursing staffs should care for HSCT patients with more interest to reduce variables disturbing sleep. Especially, more careful nursing interventions have to be considered at the time of the day before HSCT and the time of discharge.

      • KCI등재

        대학생의 오가닉 의류제품에 대한 구매행동과 인지도의 차이

        박혜령(Park, Hea-Ryung),박미령(Park, Mi-ryung),조신현(Cho, Shin-hyun) 한국산학기술학회 2015 한국산학기술학회논문지 Vol.16 No.6

        본 연구에서는 대학생들의 오가닉 의류제품에 대한 구매행동과 인지태도를 알아보고자 하였으며 오가닉 의류제품에 대한 구매경험 여부를 살펴보면 오가닉 의류제품 여성용품-생리대를 가장 많이 구입했으며 구매횟수에 대해서는 1회 구입이 가장 많았고 대학생의 구매이유는 ‘나의 건강을 위해’라는 대답이 가장 많았으며 비구매 이유는 ‘오가닉 의류제품에 대해 잘 몰라서’가 가장 많았다. 대학생들의 오가닉 의류제품 인지태도의 요인분석에서는 “고품질인지”, “매력성”, “건강효용성” 등 3항목으로 나뉘었으며 오가닉 의류제품 구매경험 집단과 비구매집단의 오가닉 의류제품에 대한 인지태도의 차이는 “건강 효용성”에서 유의미한 차이를 보이고 있어 구매경험이 없는 집단보다 “건강효용성”이 높게 나타났다. 또한 조사대상자의 특 성과 오가닉 의류제품에 대한 인지태도 차이에서는 성별, 연령, 관련전공 항목에서 “건강효용성”에서 유의한 차이를 보였으 며 거주지역에서는 “고품질 인지성”과 “건강효용성”에서 유의한 차이를 보였다. This study aims to examine and analyze consumers’ perception level and purchase behavior of organic clothing goods with . According to their purchase experience of organic clothing goods, it was found that organic textile products for women like sanitary pad were most and purchase frequency of organic clothing goods was mostly once. Among reasons to purchase organic clothing goods, ‘for my health’ was most. Non-purchase reason was mostly ‘I don’t know what organic goods are’. Therefore, there were significant awareness differences of organic clothing goods in “health efficiency” between the purchasing group and the non-purchasing group. In addition, there were significant awareness differences of demographic characteristics and organic clothing goods in sex, age, and “health efficiency” of related major items and in “high quality recognition” and “health efficiency” of residential areas.

      • KCI등재

        라이프스타일 특성에 따른 오가닉 의류제품 구매경험과 구매의도

        박혜령(Park, Hea-Ryung),박미령(Park, Mi-ryung),조신현(Cho, Shin-hyun) 한국산학기술학회 2015 한국산학기술학회논문지 Vol.16 No.5

        본 연구의 목적은 미래의 가장 중요한 소비자계층으로 부상할 대학생을 대상으로 오가닉 의류제품의 구매경험과 라이프스타일에 따른 오가닉 의류제품 구매의도를 파악하고자 하였다. 첫째, 조사대상자의 인구통계적 특성에 따른 오가닉 의류제품 구매경험의 차이에서는 거주지역을 제외하고 성별, 연령, 관련전공, 용돈, 수입에서 집단간 유의한 차이가 있는 것 으로 나타났다. 둘째, 조사대상자인 대학생을 대상으로 라이프스타일 요인구조분석을 하였는데 “웰빙지향”, “변화추구”, “친 환경주의”, “유행혁신”, “보수안전”의 가치관으로 나뉘어졌다. 셋째, 오가닉 의류제품의 “구매경험” 및 “비구매경험”에 따라 라이프스타일 특성의 하위 차원인 “웰빙지향”, “변화추구”, “친환경주의”, “유행혁신”, “보수안전”에 차이가 있는지 알아보고 자 하였는데 “웰빙지향”, “변화추구형”, “친환경주의”, “유행혁신”은 오가닉 의류제품의 구매경험집단이 비구매 경험집단보 다 높게 나타났으며 모든 하위요인 집단들인 “웰빙지향”, “변화추구”, “친환경주의”, “유행혁신”, “보수안전”이 오가닉 의류 제품 구매의도에 유의한 영향을 미치고 있는 것을 알 수 있다. This study aims to examine the college students experience and intention to purchase organic clothes according to their lifestyle as the most promising consumer class in future. First, it was found that their experience to purchase organic clothes according to the subjects demographic characteristics showed significant differences in the categories of gender, age, related major, pocket money and income from except their residential areas. Second, factor structure analysis of their lifestyles was conducted and the factors analyzed were divided into “well-being orientation”, “pursuit of changes”, “eco-friendly view”, “trend innovation”, and “conservative security”. Third, the present study examined differences in sub-dimensions of lifestyle characteristics such as “well-being orientation”, “pursuit of changes”, “eco-friendly view”, “trend innovation”, and “conservative security” depending on their experience or non-experience to purchase organic clothes and found that “well-being orientation”, “pursuit of changes”, “eco-friendly view”, and “trend innovation” were higher in the group with experience to purchase organic clothes than in that with non-experience and it was known that all sub-factor groups including “well-being orientation”, “pursuit of changes”, “eco-friendly view”, “trend innovation”, and “conservative security” had a significant influence on intnetion to purchase organic clothes.

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