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Xing-Chun Wu,Chang-Xun Fang,Jin-Yang Chen,Qing-Shui Wang,Ting Chen,Wen-Xiong Lin,Zhong-Liang Huang 한국식물학회 2011 Journal of Plant Biology Vol.54 No.4
To determine the proteomic response to UV irradiation, two cultivars, i.e., Lemont (UV tolerant) and Dular (UV sensitive), were exposed to natural and enhanced ultraviolet-B (UV-B) irradiation for 1, 7, and 14 days, and two-dimensional gel electrophoresis in combination with mass spectrometry (MS) and bioinformatics were used to compare the different proteomic responses in the leaves of the two cultivars. Thirty-nine proteins were up- or downregulated following the UV-B treatments. Among them, 30 increased or decreased more than 1.5-fold in abundance. They were further tested by using matrix-assisted laser desorption/ionization time of flight MS and performed a database search. Twentyfour proteins were thus identified. These identified proteins were mostly upregulated in Lemont, whereas only 14 of them upregulated in Dular. Nine proteins involved in glycometabolism and fatty acid metabolisms, signal transduction, and protein synthesis and folding in Dular were not changed. These results suggest that there was a complex regulative mechanism on the proteomes in rice leaves upon UV-B exposure.
Wen-Ting Ting,Ru-Wen Chang,Chih-Hsien Wang,Yih-Sharng Chen,Jih-Jong Lee 대한수의학회 2020 Journal of Veterinary Science Vol.21 No.1
Currently, the optimal resuscitation fluid remains debatable. Therefore, in the present study, we designed a trometamol-balanced solution (TBS) for use as a resuscitation fluid for hemorrhagic shock. Hemorrhagic shock was induced in 18 male Wistar-Kyoto rats, which were assigned to normal saline (NS), Ringer's solution (RS), and TBS groups. During the hemorrhagic state, their hemodynamic parameters were recorded using an Abbott i-STAT analyzer with the CG4+ cartridge (for pH, pressure of carbon dioxide, pressure of oxygen, total carbon dioxide, bicarbonate, base excess, oxygen saturation, and lactate), the CG6+ cartridge (for sodium, potassium, chloride, blood glucose, blood urea nitrogen, hematocrit, and hemoglobin), and enzyme-linked immunosorbent assay kits (calcium, magnesium, creatinine, aspartate aminotransferase, alanine aminotransferase, bilirubin, and albumin). Similar trends were found for the parameters of biochemistries, electrolytes, and blood gas, and they revealed no significant changes after blood withdrawal-induced hemorrhagic shock. However, the TBS group showed more effective ability to correct metabolic acidosis than the NS and RS groups. TBS was a feasible and safe resuscitation solution in this study and may be an alternative to NS and RS for resuscitation in hemorrhagic shock patients without liver damage.
THE INFLUENCES OF COOLNESS AND AFFINITY OF SERVICE ROBOTS ON CUSTOMERS’ BEHAVIORAL INTENTIONS
Sue-Ting Chang,Sheng-Hshiung Tsaur,Chu-Cheng Chang,Tien-Cheng Han 글로벌지식마케팅경영학회 2023 Global Marketing Conference Vol.2023 No.07
The outbreak of COVID-19 has brought significant changes to today’s life. Human contact is regarded as a source of risk. Thus, the low-contact services provided by service robots have gained more attention in the hospitality industry. However, a relatively smaller proportion of empirical research exists about service robots on the consumer side. Moreover, technology acceptance theories were mostly used in the adoption of new technology products, but the psychological aspects of consumers were rarely explored. Therefore, the stimulus- organism-response model (SOR model) was applied to explore consumers’ acceptance of adopting service robots and to understand what factors will successfully stimulate consumers’ subsequent value and behavioral responses. Furthermore, we investigated the relationship among stimulus (coolness and affinity), organism (utilitarian value and hedonic value) and response (intention to use and word-of-mouth recommendation). This study used convenience sampling and tested the hypotheses with SPSS and Smart PLS.
Factors Related to Treatment Refusal in Taiwanese Cancer Patients
Chiang, Ting-Yu,Wang, Chao-Hui,Lin, Yu-Fen,Chou, Shu-Lan,Wang, Ching-Ting,Juang, Hsiao-Ting,Lin, Yung-Chang,Lin, Mei-Hsiang Asian Pacific Journal of Cancer Prevention 2015 Asian Pacific journal of cancer prevention Vol.16 No.8
Background: Incidence and mortality rates for cancer have increased dramatically in the recent 30 years in Taiwan. However, not all patients receive treatment. Treatment refusal might impair patient survival and life quality. In order to improve this situation, we proposed this study to evaluate factors that are related to refusal of treatment in cancer patients via a cancer case manager system. Materials and Methods: This study analysed data from a case management system during the period from 2010 to 2012 at a medical center in Northern Taiwan. We enrolled a total of 14,974 patients who were diagnosed with cancer. Using the PRECEDE Model as a framework, we conducted logistic regression analysis to identify independent variables that are significantly associated with refusal of therapy in cancer patients. A multivariate logistic regression model was also applied to estimate adjusted the odds ratios (ORs) with 95% confidence intervals (95%CI). Results: A total of 253 patients (1.69%) refused treatment. The multivariate logistic regression result showed that the high risk factors for refusal of treatment in cancer patient included: concerns about adverse effects (p<0.001), poor performance(p<0.001), changes in medical condition (p<0.001), timing of case manager contact (p=.026), the methods by which case manager contact patients (p<0.001) and the frequency that case managers contact patients (${\geq}10times$) (p=0.016). Conclusions: Cancer patients who refuse treatment have poor survival. The present study provides evidence of factors that are related to refusal of therapy and might be helpful for further application and improvement of cancer care.
Angel Chao,Yi-Hao Lin,Lan-Yan Yang,Ren-Chin Wu,Wei-Yang Chang,Pi-Yueh Chang,Shih-Cheng Chang,Chiao-Yun Lin,Huei-Jean Huang,Cheng-Tao Lin,Hung-Hsueh Chou,Kuan-Gen Huang,Wen-Ling Kuo,Ting-Chang Chang,Ch 대한부인종양학회 2020 Journal of Gynecologic Oncology Vol.31 No.3
Objective: The characteristics of patients with metachronous breast and ovarian malignancies and the pathogenic role of BRCA1/2 mutations remain poorly understood. We investigated these issues through a review of hospital records and nationwide Taiwanese registry data, followed by BRCA1/2 mutation analysis in hospital-based cases. Methods: We retrospectively retrieved consecutive clinical records of Taiwanese patients who presented with these malignancies to our hospital between 2001 and 2017. We also collected information from the Data Science Center of the Taiwan Cancer Registry (TCR) between 2007 and 2015. Next-generation sequencing and multiplex ligation-dependent probe amplification were used to identify BRCA1/2 mutations and large genomic rearrangements, respectively. When BRCA1/2 mutations were identified in index cases, pedigrees were reconstructed and genetic testing was offered to family members. Results: A total of 12,769 patients with breast cancer and 1,537 with ovarian cancer were retrieved from our hospital records. Of them, 28 had metachronous breast and ovarian malignancies. We also identified 113 cases from the TCR dataset. Eighteen hospital-based cases underwent BRCA1/2 sequencing and germline pathogenic mutations were detected in 7 patients (38.9%, 5 in BRCA1 and 2 in BRCA2). All BRCA1/2 mutation carriers had ovarian high-grade serous carcinomas. Of the 12 patients who were alive at the time of analysis, 5 were BRCA1/2 mutation carriers. All of them had family members with BRCA1/2-associated malignancies. Conclusions: Our results provide pilot evidence that BRCA1/2 mutations are common in Taiwanese patients with metachronous breast and ovarian malignancies, supporting the clinical utility of genetic counseling.
The Determinants of South Korea’s Trade Balance: A Cointegrating Regression Approach
Ting-Huan Chang,Jun-De Lee,Yi-Hsien Wang 한국무역학회 2012 Journal of Korea trade Vol.16 No.3
This paper examines the key determinants of South Korea’s trade balance using three fully efficient cointegrating regression methods. We find that the trade balance, foreign income, money supply, real effective exchange rate, and domestic income are cointegrated. Consistent with the Marshall-Lerner condition, appreciation in the real effective exchange rate is negatively related to the trade balance. Our results have important implications for using exchange rate policy as a device to achieve trade balance.
류팅팅 ( Ting Ting Liu ),박창언 ( Chang Un Park ) 부산대학교 과학교육연구소 2013 교사교육연구 Vol.52 No.3
본 연구는 한국과 중국의 중등교사 양성제도를 비교함으로써 양국의 상호이해와 시사점을 도출하는데 목적이 있다. 이 목적 달성을 위해 한국과 중국의 중등교사 양성의 변천에 대한 경과를 살펴보고, 교사 자격제도 및 중등교사 양성을 위한 교육과정을 비교하였다. 비교 결과 공통적인 사항으로는 양국이 모두 교원자격에 대해 법정화 함으로서 교원의 지위를 보장하기 위한 조치를 취하고 있었다. 또한 교육학과 교과내용학 모두를 중시하고 있었다. 이에 비해 차이점으로는 교원자격검정에서 한국은 무시험검정으로 자격을 부여하는데 비해, 중국은 시험을 통해 자격을 부여하고, 그 자격도 일정기간이 경과하면 갱신하여야 하였다. 교원 양성기관에서도 한국은 대부분의 대학에서 동일한 내용을 가르치지만, 중국은 국가급, 성급, 시급 등으로 구분이 되고, 이들 기관별 교육내용이 상이하게 전개되었다. 또한 시급으로 갈수록 실습에 대한 과목이 많이 부여되었다. 특징적인 것은 한국의 교원양성 교육과정에서는 이념과 관련된 과목이 존재하지 않는데 비해, 중국의 교원양성 교육과정에서는 이념과 관련된 과목이 존재하고 있었다. 이수학점은 한국에 비해 중국이 월등히 많았다. 이러한 공통점과 차이점을 토대로 양국은 국가별 상황을 고려하되, 양국의 좋은 제도적 취지나 내용은 수용하여 각국의 교원의 전문적 자질을 함양하는데 적극 활용할 필요가 있었다. The purpose of this study is to analyze the similarities and differences of the teacher`s training system between Korea and China in middle and high school teacher. The specific research of this study are as follows. Firstly, what are the similarities and differences of the teacher`s certification system, Secondly, what are the similarities and differences of the teacher education curriculum. The finding are as follows. First, there are similarities in teacher`s certification system between the two nations: (1) the teacher`s certificate are awarded through official approval, (2) each nation bothered about the teaching profession subjects and major Secondary, there are many differences in the teacher education curriculum between two nations; (1) Korea has a certification system without examination, while China has a certification system with examination, (2) Korea has an easy courses to acquire an upper certificate, while China has an hard courses to acquire an upper certificate, (3) the kinds of certificate are various in Korea, while China has a certification system with examination, (4) Korea has not a subject related with ideologies, while China has a subject for ideologies.