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한국인(韓國人)의 주요사인(主要死因) 제거정도(除去程度)와 평균수명(平均壽命)에 관한 연구(硏究)
지기태 ( Kee Tea Chi ),김응익 ( Eung Ik Kim ) 한국보건사회연구원 1984 保健社會硏究 Vol.4 No.2
This study was conducted to examine potential gains in life expectancies when the three leading causes of death were partially or totally eliminated, based on the mortality situation during 1978-79 in Korea. It sought to ascertain what potential gains in longevity might be reasonably achieved through efforts to reduce mortality due to accidents and adverse effects, diseases of circulatory system and malignant neoplasms. In addition to the study seeks to determine how much of these potential gains can be expected during the total life span. The impressive gains theoretically achieved by total elimination do not hold up under the more realistic assumption of partial elimination or reduction. 1. Elimination of selected risks of death The potential gains in life expectancy at birth by the complete elimination are 4.27 years in male population and 4.34 years in female population. If it were possible to eliminate accidents and adverse effects as a cause of death the average length of life at birth would be increased by 2.16 years in male population and 1.40 years in female population according to mortality condition during 1978-79. The human life wasted by malignant neoplasms is estimated to be 1.89 years at ago 0 in male population and 1.72 years in female population. 2. Reduction in selected risk of death The life expectancy of a new-born child by 30 percent reduction in selected risks of death in male and female population respectively would be increased 1.09 years and 1.14 years in diseases of circulatory system, 0.63 years and 0.42 years for accidents and adverse effects, and 0.53 years and 0.50 years for malignant neoplasms. When the mortality rate for the causes of death being eliminated is relatively small, the increase in expectation of life is approximately a linear function of the proportion eliminated. In spite of the known limitation of multiple-decrement life table analysis the findings from this study have implications for practical decision making in setting up health goals, allocating resources and evaluating health programs.
( Jae Sung Lee ),( Tea Eung Kim ),( Chung Won Lee ),( Keun Young Chun ),( Byung Joon Park ),( Jong Chul Shin ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-
Adnomyosis and leiomyoma of the uterus are common benign tumors of woman at childbearing age and are frequent underlying causes of secondary dysmenorrhea, menorrhagia, urinary symptoms and subfertility. Treatment options of these diseases vary from hysterectomy to alternative and conservative treatments for adenomyosis and leiomaoma for women who design pregnancy with the potential to preserve fertility is being investigated including danazol, gonadotropin-releasing hormone (GnRH) analogues, nonsteroidal anti-inflammatory drugs (NSAID), oral contraceptives, levonorgestrel releasing intrauterine device (IUD), ablation using radiofrequency (RF) or high-intensity focused ultrasound (HIFU), and uterine artery embolization (UAE). HIFU is an effective and alterative technique for the non-invasive, powerful tissue ablation and conservative approach of symptomatic uterine fibroid. It is a noninvasive technique that uses an external ultrasound energy source to induce a thermal ablation of tissue deep under the intact skin based on its ability to concentrate ultrasound waves. This report describes three cases of term delivery in two patients with myoma and one with adenomyosis after treatment of ultrasound-guided high-intensity focused ablation (USgHIFU).
유화중합에 의한 PBA/PMMA Core/Shell 구조 라텍스 합성에서의 그래프팅 반응 속도론
박영준,김중현,박응식,황태원,김중인 한국화학공학회 1994 Korean Chemical Engineering Research(HWAHAK KONGHA Vol.32 No.5
2단계 유화중합법을 이용하여 poly(n-butyl acrylate)를 core로 하고 poly(methyl methacrylate)를 shell로 하는 라텍스 입자를 합성하고 이것의 그래프팅 효율을 용매추출법을 이용해서 구하였다. 유화중합 속도론을 그래프팅 반응에 적용하여 그래프팅 반응의 속도식을 이끌어 낼 수 있었으며 이를 이용해서 그래프팅 반응의 효율을 계산할 수 있었다. 계산된 그래프팅 반응 효율은 실험에 의해서 구한 그래프팅 반응 효율과 유사한 경향을 나타내었으며 이를 이용해서 그래프팅 반응 속도 상수 K_(ib)의 값을 구할 수 있었다. Latex particles which consist of poly(n-butyl acrylate)[p(n-BuA)] core and poly(methyl methacrylate)[PMMA] shell were prepared by two stage emulsion polymerization and the grafting efficiency(GE) of these latex particles was determined by the solvent extraction method. Kinetics of emulsion polymerization was applied to the grafting reaction and the grafting efficiency was calculated from the kinetic expression. The calculated result showed similar trend to the experimental values. The approximate value of the grafting reaction constant was obtained using this method.
포도당 및 인슐린이 인체 치은섬유모세포와 치주인대세포에 미치는 영향
한희란,김응태,유형근,신형식,Han, Hee-Ran,Kim, Eung-Tea,You, Hyung-Keun,Shin, Hyung-Shik 대한치주과학회 1998 Journal of Periodontal & Implant Science Vol.28 No.1
Diabetes mellitus is a systemic disease with profound effects on oral health and periodontal wound healing. Uncontrolled diabetes adversely affects surgical wound healing and is often associated with abnormal proliferation of fibroblasts. Human gingival fibroblasts and PDL cells were chosen because they are intimately involved in periodontal therapy and are important for the success of surgical procedure such as guided tissue regeneration. The aim of the present study was to elucidate whether cellular activity and collagen synthesis by glucose pre-treated human gingival fibroblasts and PDL cells are influenced by insulin, and whether healthy cells differ from glucose treated cells. Cells were cultured with DMEM at $37^{\circ}C$, 5% $CO_2$, 100% humidified incubator. To evaluate the effect of glucose on gingival fibroblasts and periodontal ligament cells, the cells were seeded at a cell density of $1{\times}10^4\;cells/well$ culture plates and treated with 20 and 50mM of glucose for 5 days. Then MTT assay was carried out. To evaluate the effect of insulin on glucose-pretreated cells, the cells were seeded at a cell density of $1{\times}10^4\;cells/well$ culture plates and treated with 20 and 50mM of glucose for 5 days. After incubation, $10^3$, $10^4$ and $10^5mU/l$ of insulin were also added to the each well and incubated for 2 days, respectively. Then, MTT assay and collagen synthesis assay were carried out. The results indicate that cellular activity of gingival fibroblasts significantly increased by glucose while periodontal ligament cells were unaffected and cellular activity of gingival fibroblasts and periodontal ligament cells were unaffected by insulin. Collagen synthesis of gingival fibroblast with 20mM glucose and insulin unaffected, but 50mM glucose and insulin increased than control. Collagen synthesis of periodontal ligament cell with 20mM glucose and $10^5mU/l$ insulin significantly increased than other groups and 50mM glucose pretreated PDL cells significantly increased at $10^3mU/l$ insulin but decreased at $10^4mU/l$ insulin. Our findings indicated that these cell types differed in their growth response to glucose, and the increase in collagen synthesis was significantly raised at insulin level of $10^3mU/l$ in gingival fibroblasts and periodontal ligament cells except 20mM glucose pretreated periodontal ligament cells.