소결 고속도 공구강의 내마모 특성

임태환,이수완 선문대학교 중소기업기술지원연구소 1997 선문공대 연구/기술 논문집 Vol.2 No.1

Rolling die 크기를 변화시켜 제작한 소결체 및 합금 조성을 변화시켜 제작한 고속도 공구강 소결체에 대하여 마모 실험, 고온경도 실험 등을 실시한 결과, 소결체의 마모는 abrasive wear로 일어나며 재료의 경도값이 마모율을 결정하는 주 인자가 된다고 생각한다.

백서 간재생중 H2B Histone 유전자 발현에 대한 Octamer Binding Transcription Factor의 역할

임규,방재웅,최두식,손미영,이영철,박청,김태동,김영래,박종일,윤완희,박승길,황병두 한국노화학회 2001 한국노화학회지 Vol.11 No.1

화농성 슬관절염이 동반된 수막구균성 수막염 1예

김태연,유진홍,박성환,김연식,임상현,신완식,강문원,정창훈,최문구,강지민 대한화학요법학회 1997 대한화학요법학회지 Vol.15 No.2

저자들은 최근 화농성 슬관절염과 병발한 수막구균성 수막염 1예를 체험하였고, 이는 국내에서 아직 보고되지 않은 드문 예로 사료되어 문헌고찰과 함께 보고하는 바이다. We recently experienced a case of meningococcal meningitis associated with pyogenic arthritis in a 37-year old male patient. Pyogenic arthritis developed in right knee joint during treatment for meningococcal meningitis. He was treated successfully by appropriate antibiotics and arthroscopic irrigation. To our knowledge, such a rare case has not ever been reported in Korea, Hence we report this case with a review of related literatures.

인터벌웨이트 트레이닝과 써키트웨이트 트레이닝의 效果에 關한 比較硏究

전태원,주기찬,임완기 師範大學 體育硏究所 1989 서울大學校 體育硏究所論集 Vol.10 No.2

The aim of this study was to verify comparatively the difference of the effects between I.W.T. and C.W.T. to the improvement in multilateral physicalfitness. To accomplish this purpose, the subjects consisted of 13 students in girls' middle school and they were divided into two groups by the way of random sampling: I.W.T. 7, C.W.T.6. Through 10 weeks' training in each group, such findings were gained as follows. 1. The improvement of Strength, Muscular endurance, were appeared significantly in both two groups. 2. The improvement of Power was appeared significantly in I.W.T. group, but not in C.W.T. group. 3. The decrease of % Body fat and Heart rate (at rest, in the load of 300kpm, 450kpm, 600kpm, were appeared significantly in both two groups. 4. Though the differance of effect between I.W.T. and C.W.T. was not appeared significantly in being compared by t-score, but the effect of I.W.T. was appeared much more significantly than the C.W.T. in being compared by % rate.

본태성 혈소판 증다증 2예

주기산,임현성,김미자,양태영,허경,김완중,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Essential thrombocythemia is a chronic myeloproliferative disorder of unknown origin, charcterized by excessive number of morphologically and functionally abnormal platelet in peripheral blood and abnormal proliferation of megakaryocytes in bone marrow. Its main clinical manifestations are hemorrhages and thromboses. The aim of therapy is suppression of the excessive bone marrow activity, which can be achieved by radioactive phosphorus, alkylating agent, hydroxyurea and interferon. Two cases were diagnosed at our hospital which had laboratory and clinical features compatible with this disease. We have successfully treated patient with hydroxyurea and platelet antiaggregating agent.

Irbesartan과 Lercanidipine의 병용요법이 고혈압 및 혈관재형성에 미치는 효과

이도형, 임태완, 조은지, 박현수, 정상혁, 한주희, 병창선 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

Hypertension is one of the major risk factor for cardiovascular disease and can lead to or make worse many complications, heart disease, atherosclerosis and diabetes. Thus, managing blood pressure effec tively using therapeutic drugs such as angiotensin II receptor blocker (ARB) and Ca2+ channel blocker (CCB) can be prevent other complications. Therefore, we investigated the synergistic effect of these two drugs, ir besartan and lercanidipine, for antihypertension, cardioprotection and antidiabetes. Irbesartan (28.74 mg/kg, 14.37 mg/kg) or lercanidipine (1.92 mg/kg, 0.96 mg/kg) alone or combination was administered to sponta-neously hypertensive rats (SHRs) and C57BL/6 mice. A two-week treatment of combination with irbesartan and lercanidipine significantly attenuated systolic blood pressure (SBP) and mean arterial pressure (MAP) compared with monotherapy. Futhermore. the combination therapy protected myocardial ischemia reperfusion injury more effectively than monotherapy. In vascular remodeling, combination therapy significantly diminished cuff -induced neointima formation and reduced serum -indllced vascular smooth muscle cells (VSMCs) pro-liferation compared with monotherapy. However, combination therapy had no significant synergistic effect of blood glucose regulation. Taken together, present study suggest that the combination therapy of irbesartan and lercanidipine may be more effective therapeutic strategy for the treatment of hypertension and related complications, myocardial infarction and arterial restenosis than monotherapy

뇌자기공명영상촬영술상 병변을 관찰할 수 없는 허혈성 뇌경색

김진석,김태완,임정근 啓明大學校 醫科大學 1998 계명의대학술지 Vol.17 No.4

1. 임상적으로 뇌졸중이 의심되어 증상 발생후 24시간에서 2개월까지 Brain MRI을 실시한 722명의 환자들 중 결과가 가음성인 환자는 모두 22명 (3.1%)이었다. 2. Brain MRI상 병변은 관찰되지 않으나 임상 양상 및 신경학적 이상 소견으로 추정되는 병변의 위치를 구분해 보면 뇌간부가 13명 (59%)으로 가장 많았고, 피질하부 8명 (36%), 피질 1명 (4.5%)의 순 이었다. 3. 대뇌혈관 (large cerebral artery)폐쇄 보다는 분지 동맥 (branch artery)이나 소 관통동맥 (small perforating artery)의 폐쇄에 의한 것으로 추정되는 허혈성 뇌경색의 병변의 빈도가 높았다. 4. 병력, 뇌졸증 위험 인자, 임상 양상, 심전도 검사, 심초음파 검사 및 뇌혈관조영술등에서 혈전성 뇌경색은 12명 (55%), 색전성 뇌경색은 3명 (13%), 원인이 확실하지 않은 경우는 7명(32%)으로 혈전성 뇌경색의 빈도가 뚜렷하게 높았다. 5. T1강조 영상, T2,강조 영상 및 FLAIR sequence를 같이 실시함으로써 허혈성 뇌경색의 조기 발견은 과거의 연구 보고에 비하여 상당히 높아졌으나 계속적으로 Brain MRI상 가음성인 허혈성 뇌경색이 있음으로, 허혈성 뇌경색의 조기 진단에는 새로운 기법인 확산강조 자기공명영상, 관류강조 자기공명영상, 자기공명 분광경 등의 다른 특수한 Brain MRI이 필요할 것으로 생각되며, 항상 신경학적인 검사를 통한 임상적인 진단이 선행되어야 한다. Background : Brain magnetic resonance imaging (MRI) is more sensitive than computed tomography in the diagnosis of acute ischemic stroke, but may not visualize all acute ischemic stroke. For deeper understanding of MRI negative strokes, we reviewed case histories, abnormal neurological finding, and localized ischemic lesions presumedly which were not present in brain MRI scans. Methods : Patients with a clinically definite first ischemic stroke and absence of corresponding lesion in brain MRI scans were studied retrospectively with hospital records dating from January 1994 to November 1996 and prospectively from December 1996 to August 1997. Patient with transient ischemic stroke, postictal paralysis, central nervous system infection, demyelinating disease, hemiplegic migraine, functional or hysterical cause, multiple cerebral infarction, scans within 24 hours and equivocal findings were excluded. Brain MRI was scanned with T2WI, T1WI and FLAIR sequence. Results: We studied 722 patients with clinically diagnosed definite acute ischemic stroke during the study period and identified 22 patients (3.1%) with the absence of corresponding lesion in brain MRI scan. The ischemic strokes without brain lesions on MRI scan were clinically localized to the brain stem (n=13, 59%), subcortex (n=8, 36%) and in the cortex (n=1, 4.5%). Perforating arterial and thrombotic ischemic lesions seemed to be more common than large arterial & embolic lesions. Risk factors was not different between MRI positive and MRI negative ischemic stroke. Summary: Acute ischemic stroke with absence of brain lesion in MRI scans is more common in brain stem and subcortex than in the cortex. There is some potential limitation of standard MRI scan for diagnosis of acute ischemic stroke, therefore further scans with new imaging studies such as perfusion/diffusion weighted magnetic resonance imaging are required in selected cases.

대동맥 이첨판과 승모판 이탈증을 동반한 대동맥 판하부 협착 1예

김용화,장경식,양태영,임영국,안기완,홍순표 朝鮮大學校 附設 醫學硏究所 1993 The Medical Journal of Chosun University Vol.18 No.1

Discrete subaortic stenosis is a rare cardiac disorder especially in Orientals which occupies eight to ten percent of aortic stenosis, It occurs mainly before age of eighteen and accompanies with aortic valve abnormalities such as aortic stenosis, supravalvrlar stenosis, bicuspid valve and muscular hypertrophic subaortic stenosis, and other cardiac abnormalities such as ventricular septal defect, pulmonary stenosis and coarctation of aorta. There is no report of discrete subaortic stenosis accompanied with mitral valve prolapse. The major complications of discrete subaortic stenosis are aortic insufficiency, and subacute bacterial endocarditis. We report a case of asymptomatic nineteen-year-old male of discrete subaotic stenosis with bicuspid aortic valve and mitral valve prolapse, which is comfirmed by two-dimensional and Doppler echocardiography including transesophaigeal echocardiography.

Determination of Doping Density in GaAs Semiconductor by Wavelength-Dependent Photoacoustic Spectroscopy

Lim, Jong-Tae,Choi, Ok-Lim,Boo, Doo Wan,Choi, Joong-Gill Korean Chemical Society 2014 Bulletin of the Korean Chemical Society Vol.35 No.3

The wavelength dependence of the photoacoustic signal for n-type GaAs semiconductors in the region of the band-gap energies was investigated. The significant changes in the phase and amplitude of the photoacoustic signal near the band-gap absorption wavelengths were observed to occur when the Si-doping densities in GaAs were varied. Particularly, the first derivatives of the photoacoustic phase vs. wavelength graphs were evaluated and fitted with single Gaussian functions. The peak centers and the widths of the Gaussian curves clearly showed linear relationships with the log values of the Si-doping densities in n-type GaAs semiconductors. It is proposed that the wavelength-dependent PA spectroscopy can be used as a simple and nondestructive method for measuring the doping densities in bulk semiconductors.

Polymorphisms of Transmembrane Channel-like 1 Gene are Associated with Kawasaki Disease in Korean Population

Lim, Tae-Wan,Kim, Su-Kang,Ban, Ju-Yeon,Chung, Joo-Ho,Song, Jeong-Yoon,Yoon, Kyung-Lim,Park, Sung-Wook,Kim, Keon-Sik,Shin, Ok-Young The Korean Society of Toxicogenomics and Toxicopro 2009 Molecular & cellular toxicology Vol.5 No.4

Kawasaki disease (KD) is believed to be infectious but etiology and the mechanism of development remain elusive. The aim of this study was to investigate the association between transmembrane channel-like 1 (TMC1) gene and KD. One hundred nine KD patients and 424 normal controls were enrolled. Of all KD patients, 34 developed coronary artery lesions (CALs). Eleven single nucleotide polymorphisms (SNPs) within TMC1 gene were selected and SNP genotyping was performed by the direct sequencing. Genotype frequencies were analyzed with the SNPAnalyzer, Helixtree, and SNPStats programs. In the present study, six SNPs (rs7851577, rs10781105, rs2589615, rs1663743, rs1373628, and rs1373626) were significantly associated with the risk of KD. In further haplotype analysis, one haplotype (CGGACCCT) showed a significant association between KD and control groups. These results suggest that TMC1 gene may be a susceptibility gene for KD in Korean population.