과도한 운동으로 발생한 횡문근융해증에 의한 급성신부전증 1예

문철호,류보열,모성환,김태종,기장도,박용관,김용환,정종훈 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Rhabdomyolysis may be defined as a clinical and laboratory syndrome which releases muscle cell contents into the plasma, such as creatine phosphokinase, due to skeletal muscle injuries. It can be the result of many diverse causes including muscle disease, ischemia, genetic disorder, metabolic disorder, infectious disease, drugs, comatose state, trauma or vigorous exercise that can lead to acute renal failure as a complication. Since first reported in 1941, rhabdomyolysis-induced acute renal failure has been documented many times, and the major causes of this disease are carbon monoxide poisoning, snake bites, and etc in Korea Reports of acute renal failure after exercise-related rhabdomyolysis with myoglobinemia are rare. We report a case of acute renal failure caused by exercise-related rhabdomyolysis in a 20 year old man.

마이야르 반응에 의한 BSA-갈락토만난 복합체의 구조 및 유화 특성

문태화 서울대학교 농업개발연구소 1999 농업생명과학연구 Vol.3 No.-

Bovine serum albumin-galactomannan (BSA-GM) conjugates were prepared through Mail;lard reaction. With an increase in reaction ratio of GM to BSA, 2.5-7 moles of GM were bound to 1 mole of native BSA. Intrinsic fluorescence analysis suggested that the surface of each conjugate was covered with GM and the conformation of hydrophobic interior was not changed. Binding ability of BSA-GM conjugates to a hydrophobic probe was higher as compared to native BSA. Secondary structure showed little difference in native BSA and BSA-GM conjugates. Thus, it would suggest that the covalent bond between BSA and GM was formed outward of the α-helical region. The emulsifying properties of BSA-GM conjugates were improved as compared with those of native BSA and BSA-GM mixture. The improvement of emulsifying properties was due to the hydrophilicity, steric hindrance and viscoelastic properties caused by GM.

산 가수분해와 수분-열처리가 난소화성 서류 전분 형성과 구조에 미치는 영향

문태화 서울대학교 농업개발연구소 2000 농업생명과학연구 Vol.4 No.-

To investigate the effects of acid hydrolysis and heat-moisture treatment(HMT)on formation and structural characteristics of resistant starch(RS), sweet potato and potato starches, which had been partially hydrolyzed with 1N HCℓ at 35℃ for 8hr and then subjected to autoclaving-cooling(AC) treatment, were heated at 100℃ for 16hr after adjusting the moisture content to 20% or 30%. RS content of the starches increased by more than three times by HMT following acid hydrolysis. Differential scanning calorimetric thermogram of the acid hydrolyzed starch with HMT revealed a decreased peak transition temperature(Tp). It could be ascribed to the formation of new short starch chains by the acid hydrolysis. These chains were presumed to be the main component of the crystalline region, which led to the formation of less stable crystallites during AC and HMT. The enthalpies of RS were increased by HMT. X-ray diffraction patterns of RS revealed that the peak resolution and crystallinity were enhanced by HMT. Especially, sweet potato RS exhibited sharper and larger peaks at 2 Θ = 24˚ - 28˚. RS formed by AC and HMT of acid hydrolyzed starch showed the changes in X-ray diffraction pattern. 13C CP/MAS solid NMR spectra of all the RS displayed chemical shifts and increased double helix content by these treatments.

다당류를 이용한 수용성 난황 단백질의 분리

문태화(Tae Wha Moon),이현종(Hyun Jong Lee) 한국응용생명화학회 1993 Applied Biological Chemistry (Appl Biol Chem) Vol.36 No.4

Response surface methodology was employed to investigate the conditions for separating water-soluble proteins from egg yolk using sodium alginate, propylene glycol alginate (PGA), sodium carboxymethylcellulose (CMC) and pectin which are approved as food additives. Effects of plysaccharide concentration and pH of the reaction system on protein and lipid contents in the supernatant were evaluated at respectively five and three levels of concentration and pH using rotatable hexagon design. Statistical analysis showed that pH of the system was a more important factor than polysaccharide concentration as it significantly affected all two responses. Separating conditions established by a graphical optimization technique were 0.23∼0.25% of sodium alginate at pH 5.9∼6.0, 0.15∼0.17% of PGA at pH 4.3∼4.5, 0.30∼0.31% of CMC at pH 3.0, and 0.09∼0.10% of pectin at pH 5.6∼5.8.

Flow Characteristics in Packed Bed of Cape Jasmine Powders in U-column Microwave Assisted Extraction System

Soo-Jin Jun,Tae Wha Moon,Jae-Kun Chun 한국산업식품공학회 1998 산업 식품공학 Vol.2 No.1

Effects of Water to Rice Ratio and Bulk Density on the Thermal Conductivity of Cooked Rice

Young-Jin Lee,Jae-Kun Chun,Tae-Wha Moon,Koo-Min Chung 한국산업식품공학회 2001 산업 식품공학 Vol.5 No.3

거제시 노인생활실태분석 및 노인복지 발전방안

문선화,김기태,윤은경 釜山大學校 社會福祉硏究所 1999 社會福祉硏究 Vol.9 No.-

Maltosyl-erythritol의 이화학적, 관능적 특성과 난충치성 규명

문태화 서울대학교 농업개발연구소 2001 농업생명과학연구 Vol.5 No.-

Maltosyl(G2)-rythritol is a major transfer product obtaind by transglycosylation reaction with maltogenic amylase from Bacillus stearothermophilus(BSMA). In this study, some of the physicochemical, sensory and physiological properties were investigated. G2-erythritol was identified by using thin layer chromatography and purified with gel permeation chromatography. The viscosity and heat-stability of G2-erythritol were similar to those of erythritol, showing no significant effect of temperature, concentration and pH. In the colorability test, at pH 4 heating up to 120℃ caused little browning of G2-erythritol. However, at pH 7 browning of G2-erythritol increased with increasing heating temperature over 100℃. Sensory evaluation with magnitude estimation showed that relative sweetness of G2-erythritol was about 40% of sucrose. Its sweetness attributes determined by quantitative descriptive analysis indicated that negative properties, such as bitterness and astringency, were reduced as compared with erythritol. In addition, the duration and time to reach maximum intensity of sweetness analyzed by time-intensity parameters did not show any significant differences as compared to those of erythritol. Dental caries suppression effect of G2-erythritol was also determined. G2-erythritol was not utilized either as a substrate for the lactic acid production or for water-insoluble glucan synthesis by Streptococcus sobrinus NRRL 14555. Inhibition tests of dextransucrase and mutansucrase showed that relative inhibition of G2-erythritol was about 70 times higher than that of erythritol. These results suggest that G2-erythritol improves sweetness characteristics of erythritol and can be used as a new non-cariogenic sweetener.

임상적 비기능성 뇌하수체선종의 내분비학적 및 형태학적 특징

김태승,정현주,허갑범,이현철,임승길,이은직,김경래,송영득,남문석,이규창,조재화,최중언,정상섭,김선호 대한내분비학회 1994 Endocrinology and metabolism Vol.9 No.3

Forth-nine patients with clinically nonfunctioning pituitary adenomas were evaluated clinically, endocrinologically and morphologically in this study. The results obtained were as follows. 1) The mean age was 47.1 years(range 23 to 76 years), and 22 were male(44.9%) and 27(55.1%) female. 2) The major clinical manifestations of male patients were visual disturbance(72.7%), headache(54.5%), loss of libido(45.5%), but those of female visual disturbance(59.6%), headache(48.1%), amenorrhea(48.1%), loss of body hair(25.9%), and galactorrhea(22.2%). 3) All were macroadenomas evaluated by CT scan, and in the male patients 16(72.7%) were grade Ⅲ and 6(27.3%) grade Ⅳ by Hardy classification, and in the female patients 6(22.2%) were grade Ⅱ, 12(44.4%) grade Ⅲ, and 9(33.3%) grade Ⅳ. 4) The elevation of serum prolactin were observed 7(31.8%) out of male, and 24(88.9%) of female. 5) Combined stimulation test revealed that GH insufficiency was 89.6%, ACTH 58.9%, LH 58.7%, FSH 51.1 %, and TSH 50.0% and hormone insufficiency more than 4 pituitary hormone was 54.2%. 6) Prolactin response to TRH decreased in 12(70.6%) of 17 patients with normal basal prolactin, and 19(76.0%) of 25 with elevated prolactin. 7) Immunohistochemistry revealed that null cell adenoma was 57.1%, gonadotrope adenoma 26.5%, plurihormonal adenoma 8.0%, silent corticotrope adenoma 4.0%, thyrotrope adenoma(2.0%), and lactotrope adenoma(2.0%). 8) The ultrastructural characteristics examined by electron-microscopy were similar despite of immunohistochemical differences. In summary, the prevalance of clinically nonfunctioning pituitary adenoma was middle aged men and women, and their main symptoms were visual disturbance and headache. Hyperprolactinemia and pituitary hormone insufficiency more than 4 hormone were observed commonly. Most of them were null cell adenoma and gonadotrope adenoma examined by immunohistochemistry. Further study using modern techniques: cell culture, subunit-immunostaining. And Northern blot analysis of mRNA for pituitary hormone or subunit, will be needed to clarify null cell adenomas(J Kor Soc Endocrinol 9: 220-212, 1994).

Differentiation of gallbladder adenomyomatosis from early-stage gallbladder cancer before surgery

Jisum Moon,Yong Chan Shin,Tae-Gil Heo,Pyong Wha Choi,Jae Il Kim,Sung Won Jung,Heungman Jun,Sung Min Jung,Eunhae Um 한국간담췌외과학회 2019 Annals of hepato-biliary-pancreatic surgery Vol.23 No.4

Backgrounds/Aims: This study aimed to compare the perioperative and clinical outcomes in patients undergoing laparoscopic cholecystectomy for gallbladder adenomyomatosis (GBA) or early-stage gallbladder cancer (GBC). Methods: The perioperative and clinical outcomes of 194 patients diagnosed with GBA and 30 patients diagnosed with GBC who underwent laparoscopic cholecystectomy in our institution from January 2011 to December 2017 were retrospectively compared. Results: There were no significant differences between the GBA and GBC groups in sex (male:female ratio 1.0:0.8 vs. 1.0:0.7, p=0.734), BMI (23.9±3.4 vs. 24.0±3.8 kg/㎡, p=0.916), or preoperative liver function tests. Patients in the GBC group were significantly older (50.5±14.1 vs. 65.9±10.6 years, p<0.001) and had a higher ASA grade (40.3 vs. 63.4% grade II or III, p=0.043) than patients in the GBA group. Although there was no significant difference in preoperative diagnostic methods (p=0.442), the GBC group showed a significantly higher rate of misdiagnosis on preoperative imaging compared with postoperative histopathologic findings (30.9% vs. 53.3%, p=0.011). There were significantly more patients with gallstones in the GBA group than in the GBC group (68.6% vs. 40.0%, p=0.004). Conclusions: In older patients hospitalized for biliary colic without gallstones but with a thickened gallbladder wall with inflammation on preoperative diagnostic exam, the possibility of early-stage GBC should be considered.