http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Stefan Schwan,C. Ludtka,A. Friedmann,T. Mendel,H. J. Meisel,A. Heilmann,I. Kaden,F. Goehre 한국조직공학과 재생의학회 2017 조직공학과 재생의학 Vol.14 No.6
Autologous disc cell transplantation (ADCT) is a cell-based therapy aiming to initiate regeneration of intervertebral disc (IVD) tissue, but little is known about potential risks. This study aims to investigate the presence of structural phenomena accompanying the transformation process after ADCT treatment in IVD disease. Structural phenomena of ADCT-treated patients (Group 1, n = 10) with recurrent disc herniation were compared to conventionally-treated patients with recurrent herniation (Group 2, n = 10) and patients with a first-time herniation (Group 3, n = 10). For ethical reasons, a control group of ADCT patients who did not have a recurrent disc herniation was not possible. Tissue samples were obtained via micro-sequestrectomy after disc herniation and analyzed by micro-computed tomography, scanning electron microscopy, energy dispersive spectroscopy, and histology in terms of calcification zones, tissue structure, cell density, cell morphology, and elemental composition. The major differentiator between sample groups was calcium microcrystal formation in all ADCT samples, not found in any of the control group samples, which may indicate disc degradation. The incorporation of mineral particles provided clear contrast between the different materials and chemical analysis of a single particle indicated the presence of magnesium-containing calcium phosphate. As IVD calcification is a primary indicator of disc degeneration, further investigation of ADCT and detailed investigations assessing each patient’s Pfirrmann degeneration grade following herniation is warranted. Structural phenomena unique to ADCT herniation prompt further investigation of the therapy’s mechanisms and its effect on IVD tissue. However, the impossibility of a perfect control group limits the generalizable interpretation of the results.
<i>SPITZER</i>MICROLENS MEASUREMENT OF A MASSIVE REMNANT IN A WELL-SEPARATED BINARY
Shvartzvald, Y.,Udalski, A.,Gould, A.,Han, C.,Bozza, V.,Friedmann, M.,Hundertmark, M.,Beichman, C.,Bryden, G.,Novati, S. Calchi,Carey, S.,Fausnaugh, M.,Gaudi, B. S.,Henderson, C. B.,Kerr, T.,Pogge, R. IOP Publishing 2015 The Astrophysical journal Vol.814 No.2
<P>We report the detection and mass measurement of a binary lens OGLE-2015-BLG-1285La, b, with the more massive component having M-1 > 1.35M(circle dot) (80% probability). A main-sequence star in this mass range is ruled out by limits on blue light, meaning that a primary in this mass range must be a neutron star (NS) or black hole (BH). The system has a projected separation r(perpendicular to) = 6.1 +/- 0.4 AU and lies in the Galactic bulge. These measurements are based on the 'microlens parallax' effect, i.e., comparing the microlensing light curve as seen from Spitzer, which lay at 1.25 AU projected from Earth, to the light curves from four ground-based surveys, three in the optical and one in the near-infrared. Future adaptive optics imaging of the companion by 30 m class telescopes will yield a much more accurate measurement of the primary mass. This discovery both opens the path and defines the challenges to detecting and characterizing BHs and NSs in wide binaries, with either dark or luminous companions. In particular, we discuss lessons that can be applied to future Spitzer and Kepler K2 microlensing parallax observations.</P>