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      • 만성폐쇄성폐질환의 중증도와 폐고혈압 및 폐성심으로 진행과의 상관관계

        김형호,박철진,이준,장광표,하성일,이재록,하재화,권세훈,권용운,윤성호,이승일 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.2

        Background: From many previous studies, Pulmonary hypertension is the known independent predictive factor of the mortality in COPD. Also pulmonary hypertension is the major cardiovascular complication of COPD and is associated with the progression to cor pulmonale and poor prognosis. Author want to analyze the correlation between pulmonary hypertension and the severity of COPD which are classified by forced expiratory volume in one second, and the extent of progression to corpulmonale. Methods: Retrospectively we investigated the medical records of 118 patients with COPD who had pulmonary function test and echocardiogaphy more than one times during one-year follow-up (from June, 2005 to May, 2006) at respiratory division in chosun university hospital, and then 50 patients were enrolled in this study. We classified the severity from FEVl in pulmonary function test based on the GOLD guideline, also this was comparably analyzed with RVSP, RVIDd, Visual Grading from echocardiography. Results: 16 patients out of 50 were classified as moderate severity, 25 patients were severe, and 9 patients were very severe group. RVSP was higher in more severe groups than less severe groups but when it comes to pulmonary hypertension that RVSP is over 35 mmHg, there was no valid difference lies in those groups. As FEVl decreases RVSP and RVIDd increases, and observed relationship between RVSP which was classified as below 35 mm and above 35 mm groups and visual grading which was classified as normal and dilatated groups revealed valid correlation, Conclusion: As pulmonary function decreases, progression to pulmonary hypertension and cor pulmonale increases but there was no remarkable difference of prevalence in above moderate severity groups. 연구배경 폐고혈압은 이전의 많은 연구에서 만성폐쇄성폐질환에서 독립적인 사망의 예측인자로 알려져 있다. 또한 폐고혈압은 만성폐쇄성폐질환의 주요한 심혈관계 합병증이며, 폐성심으로의 진행 및 불량한 예후와도 관련되어 있다. 이에 저자는 폐고혈압과 1초간 노력성호기량으로 분류되는 만성폐쇄성폐질환의 중증도 및 폐성심으로의 진행 정도를 비교 분석하여 이들의 상관관계를 밝혀보고자 한다. 방법 2005년 6월부터 2006년 5월까지 1년 동안 본 병원 호흡기 내과에서 폐기능검사와 심장초음파 검사를 각각 1회 이상 시행한 적이 있는 118명에 한하여 의무기록을 후향적으로 조사하여 이 중에서 50명을 대상으로 하였다. 폐기능검사 시행 결과 얻은 1초간 노력성호기량을 바탕으로 GOLD guideline에 따라 중증도를 분류하였으며 이를 심초음파 시행 결과 얻은 우심실수축기압, 확장기말 우심실내부간격, 시각등급과 비교분석하였다. 결과 대상 환자 50명중 16명은 중등증, 25명은 중증, 9명은 최고중증 그룹으로 분류되었다. 우심실수축기압은 중증도가 높은 그룹에서 낮은 그룹에 비해 더 높게 나타났으나 폐고혈압에 해당하는 우심실수축기압이 35 mmHg이상인 환자에 있어사는 각 그룹간에 유의한 차이를 보이지 않았으며, 확장기말 우심실내부간격, 시각등급 또한 중증도와 유의한 차이를 보이지 안항ㅆ다. 1초간 노력성호기량이 감소함에 따라서는 우심실수축기압, 시각등급은 증가하였으며 우심실수축기압을 35mmHg 미만과 이상인 그룹으로, 시각등급을 정상과 확장이 있는 그룹으로 분류하여 비교한 결과에서는 유의한 상관관계를 나타냈다. 결론 폐기능이 감소할수록 페고혈압 및 폐성심으로의 진행이 증가하였으나 폐기능검사에서 중등도 이상의 그룹에서 유병률의 차이는 크지 않았다.

      • KCI등재

        당근 육종에 있어서 계통선발 평점에 관련된 主要 形質들의 經路係數 分析

        표재수,이상우,김주현 경상대학교 농업생명과학연구원 2002 농업생명과학연구 Vol.36 No.2

        당근 육종 과정 중 유망계통으로 선발되는 기준인 선발 평점이 주로 어떤 형질들에 의해 크게 영향받는가를 알고자 하였다. 5년에 걸쳐 봄 재배작형으로 시험한 자료를 가지고 상관 및 경로계수 분석을 통하여 선발평점에 미치는 여러 형질들의 직ㆍ간접효과를 조사한 바, 각 형질의 선발 평점에 대한 기여도는 년차에 따라 달랐다. 따라서 가장 큰 직접효과나 간접효과를 나타내는 형질은 매년 변하였다. 그러나 거의 항상 비교적 높은 직ㆍ간접 효과를 나타내는 형질은 찾을 수 있었는데 이는 근중과 고환성이었다. 이들 다음으로는 엽장과 수경등이었다. 반면 엽수, 지근, 근형, 근피특성 등은 직ㆍ간접효과가 가장 작았다. This study was conducted to clarify the direct and indirect effects of major morphological characters affecting selection score of carrot. The field experiment was carried out five times from 1991 to 1995. Root weight, number of leaf, leaf length, crown diameter, root diameter, root length, branch root, root cracking, bolting, uniformity, root-tail form, root shape, leaf weight, total weight, smoothness of root skin, hypertrophy of root and selection score were investigated. No character constantly showed the highest direct/indirect effect. Therefore the character showed the highest direct/indirect effect changed year to year. But it was possible to find out which characters were more important, or not. In frequency of high-ranked direct/indirect effect, two characters, root weight and root-tail form, were considered more important. The next characters were leaf length and crown diameter. The lowest were leaf number, branch root, smooth of root skin, and root shape.

      • 계산도구의 활용과 오차비교

        이성철,전상표 남서울대학교 2004 남서울대학교 논문집 Vol.10 No.2

        컴퓨터의 발달에 따라 수학문제 해결에 컴퓨터를 이용하는 컴퓨터대수 시스템을 적용하고 있다. 본 논문에서는 컴퓨터대수 시스템 중 많은 사용자가 선호하는 Mathematica와 Maple을 이용하여 다양한 수치적분을 계산하고 이때 발생하는 실제 넓이와의 오차를 비교하였다.

      • KCI등재후보

        설편평세포암에서 CD44, MMP-2, MMP-9, TIMP-1의 발현

        이상화,표성운,김영실,최목균 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

        Adhesion molecules and proteinases play an important role in the invasion and metastasis of a malignant tumor. However, there have not been many studies on tongue squamous cell carcinoma at Saint Mary's Hospital and Kangnam Saint Mary's Hospital, the Catholic University of Korea, between 1994 and 2000, and had not received chemo-or radiotherapy. The expression of the adhesion molecules CD44H, proteinases MMP-2 and MMP-9, and TIMP-1, which controls MMP activity, was analyzed by immunohistochemistry. In addition their association with the tumor size, lymph node metastasis, clinical stage, and cell differentiation was evaluated. Increased MMP-2 expression was significantly correlated with lymph node metastasis and clinical stage. However, it did not correlate with tumor size or cell differentiation. CD44H, MMP-9 and TIMP-1 expression were not significantly related to tumor size, lymph node metastasis, clincial stage and cell differentiation. The results suggest that MMP-2 is a possible immunohistochemical prognostic factor in tongue squamous cell carcinoma. Futher reasearches will be needed to investigate the additional tumor prognostic factors and their mechanisms.

      • 수학사를 이용한 수학교육의 방법

        이성철,전상표 남서울대학교 2004 남서울대학교 논문집 Vol.10 No.2

        It is the great necessity of mathematics in daily life. Also, importance of mathematics is more increase for our enhanced living in 21st century. But mathematics education of Korea is getting behind both quantity and quality, because many people think that mathematics is difficult and unaccessible. This paper give an mathematical interest through history of mathematics and present the Methods of mathematical education used on history of mathematics.

      • KCI등재

        入院患者의 進行痲痺에 關한 臨床的 硏究

        李仁杓,陳聖太 大韓神經精神醫學會 1981 신경정신의학 Vol.20 No.4

        A clinical study on fifty five general paretics who were hospitalized at National Hospital during a six year period (1975.5.1-1980.12.31) was done and the results were as followings: 1. The average admission rate of general paretics among the total inpatients was 0.78%. Since 1977, it was seen to have been declining. 2. The ratio of male to female paretics was about 5:1. 3. The mean age of clinical onset was 41 years. 4. The most of paretics lived in metropolitan areas or other major cities and they were prominently of lower socio-economic class. 5. The abnormal EEG findings were detected in 40.7% of the untreated cases and VDRL test in CSF was reactive in 75.7% of the untreated cases. 6. Total clinical remission rate was 41.8% and the more affective the clinical manifestation, the higher was the remission rate. 7. Psychiatric and neurologic symptoms were protean in manifestations.

      • 韓國産 소리쟁이屬(Rumex)의 花粉分類學的 硏究

        李相泰,金相吉,洪奭杓 성균관대학교 기초과학연구소 1985 論文集 Vol.36 No.1

        The surface characters of pollen grains of 7 out of 11 Korean Rumex species were investigated under a scanning electron microscope (JEOL 120 EX SEM). On the basis of the frequency of connected pores, Korean Rumex species were grouped into the followings: Group Ⅰ : A group in which frequency range of connected pores is not more than five……R. crispus, R. japonicus, R. aquatica. Group Ⅱ : A group in which pores are well connected, and more than five connected pores are frequent……R. acetocella, R. obtusifolius subsp. agrestis. Group Ⅲ : An intermediate one in which few have more than five connected pores, and the number is not more than seven……R. acetosa, R. conglomeratus. The number of echinae per number of pores was also different among species.

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