2003년 국내 중증급성호흡기증후군 진료 현황 및 문제점 분석

이진수,김은실,정문현,백제중,정선화,안주희,최영화,이선희,고철우,김성범,김민자,박승철,기현균,송재훈,최상호,김양수,이상오,조용균,박영훈,정숙인,김연숙,이흥범,손창희,장성희,정희진,김우주 대한감염학회 2004 감염과 화학요법 Vol.36 No.3

목적 : 2002년 말 중국에서 SARS가 발생한 이후 국내에서도 2003년 10월까지 총 3명의 추정환자, 17명의 의심환자가 보고되었다. 향후 추가적인 SARS의 유행이 우려되는 상황에서, 그간의 SARS 환자 진료에 있어서의 실질적인 준비사항, 진료 현황 등에 대한 조사를 통해 문제점을 파악하여, 향후 더 나은 대비가 될 수 있도록 개선점을 제시하고자 하였다. 재료 및 방법 : SARS로 의심되는 환자를 진료 경험이 있는 병원의료진을 대상으로 2003년 10월에 설문조사를 실시하였다. 설문에는 SARS 환자 진료 시의 실질적인 조치, 진료 현황, 병실, 응급실 및 외래에서의 격리 시설과 준비사항, 보건당국의 관리와 지원에 관한 사항을 포함하였다. 결과 : 대상이 되는 22개 병원 중 17개(17/22, 77.2%) 병원이 설문에 응하였다. SARS 환자를 위한 격리실은 응급실, 외래, 일반병실 및 중환자실에서 각각 9개(9/17, 52.9%), 5개(5/17, 29.4%), 15개(15/16, 93.7%), 4개(4/16, 25%) 병원에서 음압처리가 되어있지 않은 일인실 혹은 다인실이 사용되었고, 1개(1/16, 6.3%) 병원에서만 일반병실에서 음압격리실이 운영되었다. 입원환자의 진찰 시 개인보호구의 착용은 거의 모든 의료기관에서 이루어졌다. 보건당국에서 SARS지정병원의 시설 등을 사전에 확인한 곳은 1곳(1/12, 8.3%)이였고, 14개 병원(14/15, 93.3%)에서는 보건당국에 의뢰한 검사결과를 통하 받지 못하였다. 결론 : 의료기관에서 SARS 환자용 격리실뿐만 아니라 기존의 격리실 설비 등이 미흡하였으며, 특히 중환자실 및 외래의 준비가 더욱 부족하였다. 보건당국의 의료기관에 대한 종합적인 지원이 부족하였고, 병원과의 원활한 연계가 잘 이루어지지 않았다. SARS 만이 아닌 격리를 필요로 하는 질환의 적절한 진료를 위해 향후 병원 시설의 정비와 정부차원에서의 보다 구체적이고 실질적인 대책마련이 필요하다. Background : There was an worldwide outbreak of the Severe Acute Respiratory Syndrome (SARS) originated from China in late 2002. During that period three cases of suspected SARS and 17 cases of probable SARS were reported in Korea. With the concerns about the reemergence of SARS-coV transmission, it is important to be prepared for any possibility. So, this study is aimed to analysis the past measures in managing SARS and propose the amendatory plans to improve the preparedness. Materials & Methods : Questionnaires were collected among clinicians with any experience in managing the probable or suspected SARS cases in Oct. 2003. 17 out of 22 hospitals responded to the questionnaire. The contents in the questionnaire were practical activities, personal equipments, response plans, isolation facilities in emergency centers, outpatient clinics, general wards and intensive care units, and relationship with the public health department. Results : The dedicated isolation rooms in emergency centers, outpatient clinics, general wards, and intensive care units were prepared in 9 (9/17, 52.9%), 5 (5/17, 29.4%), 15 (15/16, 93.7%), and 4 (4/16, 25.0%) hospitals, respectively. Except for one hospital that newly made negative pressure room for SARS, single or multi-bed rooms without airborne infection control were used in all the other hospitals. The personal precaution principles were kept quite well in general wards. Before the designation of SARS hospital by the public health department prior evalution to see if the hospital was suitable for managing SARS was conducted in only 1 (1/12, 8.3%) hospital. The results of laboratory diagnosis were reported back in 1 (1/15, 6.6%) hospital. Conclusions : The isolation facilities which can control airborne infection were almost deficient not only for SARS but also for other respiratory transmissible diseases. For the infection control of transmissible diseases including SARS, more investment is needed on medical facilities and comprehensive support from the public health department required.

Effect of Mn and C on Age Hardening of Fe–Mn–Al–C Lightweight Steels

Sung‑Won Park,Jun Young Park,Kyong Mox Cho,Jae Hoon Jang,Seong‑Jun Park,Joonoh Moon,Tae‑Ho Lee,Jong‑Ho Shin 대한금속·재료학회 2019 METALS AND MATERIALS International Vol.25 No.3

The effects of Mn and C content on the age hardening of Fe–Mn–Al–C lightweight steels, which have austenitic or duplex(austenite and ferrite) microstructures, were investigated. An increase in Mn content induced a delay of the age hardeningthat is caused by the formation of intra-granular κ-carbides. In order to interpret the effect of Mn content, first-principlescalculations were conducted using the supercells of Fe24Al8C8,Fe24Al8C7,Fe24(Al7Mn)C8, and Fe24(Al7Mn)C7. The calculationsshowed that an increase in Mn content could be the source of the delay of the intra-granular κ-carbide formation bysuppressing C atom’ occupation of the vacancy at the body-centered site of L12. An increase in C content accelerated theformation of intra-granular κ-carbides, which induced the intense age hardening, and coarse inter-granular κ-carbides, whichresulted in significant decrease in impact absorbed energy due to inter-granular fracture.

歷代醫家들의 升降論에 對한 文獻的 考察

文聖喆,金聖勳 대한동의병리학회 1997 동의생리병리학회지 Vol.11 No.1

宇宙萬物의 運動形式이며, 人體에서도 陰陽五行學說과 더불어 生命活動을 營爲하는 基本原理로 認識되고 있는 升降論에 대하여 《黃帝內徑》중에 升降과 關係있는 原文을 중심으로 升降의 槪念을 考察하고, 歷代醫家들의 說을 宋以前, 金元代, 明代, 淸代로 區分하여 學派를 不問하고 升降學說과 有關한 說을 中心으로 比較, 檢討하였다. Through the bibliographical on the Seungang, ascending & descending theory of ancient medical scholars for many generations, the results are obtained as follows: 1. In Huang Ti Nei Ching(黃帝內經), the concept of Seunggang was formed into a systemic medical theory, the basic pattern of motions of everything in universe, and also classified as Seunggang of clear yang and turbid yin, Seunggang of bowel and viscera, Seunggang of herbal medicine. The pathology of Seunggang, and its treatment were explained in detail, too. 2. Before the Song(宋) dynasty, HwaTa(華陀) Zhang Zhong jing(張仲景), So WonBang(巢元方), Wang Do(王燾) argued about the ascending & descending of various disease on the basis of the NeiChing. 3. In Kum-Won(金元) dynasty, Li Dong Won(李東垣), ones of four great doctors thought spleen and stomach as the main axis of ascending & descending movement, and emphasized supplementing digestive tract and activating yang as chief treating methods. Zhu Danxi perceived the theory that Yang often in excess. Yin often in shortage, and he emphasized the treating method of nourishing Yin and relieving fire. 4. In Myong dynasty, Wang Lyun(王綸) emphasized the treating method of supplying Qi and nourishing Yin on the basis of the theory of Donghen(東垣), Danxi(丹溪). Li Shi Jin(李時珍) expatiated the QiMei, Sunggang of medical herbs on the basis of the theory of Neiching, Zhang Won SO(張元素), ZhangKeBin(張介賓), taking a serious view of ascending of priniordial Yang in vital portal, presented the theory of QiChil that bulids up the foundation of SungGang of five parenchymatous viscera. 5. In Ching dynasty, the theory of Sunggang was developed on the point of view of bowel and viscera Whang Won Er(黃元御) insisted the theory of left ascending & right descending, and explained the Sunggang of five element and five parenchymatous viscera through classifying the middle Qi into four grade, half ascending, ascending, half descending, descending. Ha Mong Yo(何夢瑤) presented the SungGang of five parenchymatous viscera. Yie Tianshi(葉天士) developed the theory of the spleen & stomach on Myong dynasty. and established the treatment of TongKangWeTak(通降胃濁法) by classifying the SungGang of spleen & stomach. Wu Ju Tong(吳鞠通) presented the treatment of ascending & descending, according to the demonstration of triple heater. Dang Yong Chun(唐容川) took a serious view of the SungGang of Qi & Blood. Suk Su Dang(石壽棠) asserted the theory of dryness & dampness and he regarded maintaining the blance of dryness & dampness. As the method of maintaining to balance of ascending & descending. Zhang Suk Soon(張錫純) emphasized the function of the atmosphere succesing the theory of Yu Ka Un(喩嘉言). Tu Hak Hae(調學海), one who made final settlement of the theory of SungGang, made overall presentation about the SungGang, and criticized the theory of left ascending & right descending. He also insisted that SungGang must be divided to inside and outside.

黃江의 水質과 植物플랑크톤群集에 관한 硏究

文成基,洪菜圭,李相薰,鄭鍾文 慶星大學校 1994 論文集 Vol.15 No.2

A Study on water quality and phytoplakton community was carried out from April, 1992 to March, 1993 in Hwang-Kang. The results obtained on this study are as follows. The value of environmental factors about water quality such as water temperature, pH, precipitation, DO, BOD, NH??₄-N, NO??₂-N, NO??₃-N and PO??₄-P were ranged 1.8-30℃, 6.7-8.4, 3.0-183.6mm, 8.4-14.8 mg/l, 0.7-3.0mg/l, 0.01-0.09 mg/l, 0.10-3.80 mg/; and 0.01-0.19 mg/l respectively. The phytoplankton are identified as 235 taxa including 78 genera, 202 species, 29 varieties and 4 forms. In these study areas the common species occurred frequently were Cyclotella meneghiniana, Fragilaria crotonensis, Melosira varians and Synedra ulna. The causative species of red ride were identified as Microcystis aeruginosa, Trachellomonas hispida, Ceratium hirundinella, Peridinium cinctum, Melosira italica and Staurastrum dorsidentiferum var. ornatum in the areas. The lowest standing crops(20.1 cells/ml) were recorded on January, 1993 and the highest(1,993 cells/ml) were recorded on May, 1992. According to the seasonal succession, dominant species were Fragillaria crotonensis in Spring, Actinastrum hantzschii var. elongatum, Peridinium bipes, Scenedesmus ellipsoidus for. flagellispinosus in Summer, Ceratium hirundinella, Melosira granulata var. angustissima in Autumn and Fragillaria crotonensis in Winter. Saprobic index showed that all stations were β-mesosaprobic.

3차원 물체 복원과 자료 압축을 위한 적응 Simplex-Mesh 기술의 응용

문성환,조용군,강훈 중앙대학교 정보통신연구소 1999 정보통신연구소논문집 Vol.1 No.1

대부분의 3차원 물체 복원 기술은 물체를 다수의 평면으로 나누어 물체의 표면을 근사시켜 표현한다. 주어진 분류치를 사용하여 mesh를 초기화시키는 Marching Cubes 알고리듬과 Delaunay Tetrahedrisation이 널리 사용되고 있다. 이와 더불어 deformable 모델은 적은 수의 가정만으로도 다양한 종류의 데이터들에 대한 복원 및 재구성을 할 수 있기 때문에 일반적인 물체 복원에 적합하다. 현재 deformable 모델이 기반이 된 복원 시스템에 대한 연구가 활발히 진행중이다. 본 논문에서는 곡면으로 이루어진 물체에 대해서 적응 simplex mesh 기술을 바탕으로 3차원 물체를 압축, 복원하는 방법을 제시한다. 이 방법은 미리 정해진 mesh 구조를 변형시키고 곡률과 같은 기하학적인 특성들을 다시 설정하면서 본래의 3차원 물체로 접근시킨다. 시뮬레이션을 통해서 높은 압축률로 물체롤 복원하고, 물체의 모양을 최적으로 기술하기 위해 정점들이 곡률이 높은 곳으로 집중되는 것을 보인다. Most of the 3D object reconstruction techniques divide the object into multiplane and approximate the surfaces of the object. The Marching Cubes Algorithm which initializes the mesh structure using a given isovalue, and Delaunay Tetrahedrisation are widely used. Deformable models are well-suited for general object reconstruction because they make little assumptions about the shape to recover and they can reconstruct objects from various types of datasets. Now, many researchers are studying the reconstruction systems based on a deformable model. In this paper, we propose a novel method for reconstruction of 3D objects. This method, for a 3D object composed of curved planes, compresses the 3D object based on the adaptive simplex-mesh technique. It changes the pre-defined mesh structure, so that it may approach to the original object. Also, we redefine the geometric characteristics such as curvatures. As results of simulations, we show reconstruction of the original object with high compression and concentration of vertices towards parts of high curvature in order to optimize the shape description.

적응 Simplex-Mesh 기술에 기반한 3차원 물체 복원과 자료압축

문성환,강훈,조용군 중앙대학교 생산공학연구소 1999 생산공학연구소 논문집 Vol.8 No.1

대부분의 3차원 물체 복원 기술은 물체를 다수의 평면으로 나누어 물체의 표면을 근사시켜 표현한다. 주어진 분류치를 사용하여 mesh를 초기화시키는 Marching Cubes 알고리듬과 Delaunay Tetrahedrisation이 널리 사용되고 있다. 이와 더불어 deformable 모델은 적은 수의 가정만으로도 다양한 종류의 데이터들에 대한 복원 및 재구성을 할 수 있기 때문에 일반적인 물체 복원에 적합하다. 본 논문에서는 곡면으로 이루어진 물체에 대해서 적응 simplex mesh 기술을 기반으로 3차원 물체를 압축 복원하는 방법을 제시한다. 이 방법은 미리 정해진 mesh 구조를 변형시키고 곡률과 같은 기하학적인 특성들을 다시 설정하면서 본래의 3차원 물체로 접근시킨다. 시뮬레이션을 통해서 높은 압축률로 물체를 복원하고, 물체의 모양을 최적으로 기술하기 위해 정점들이 곡률이 높은 곳으로 집중되는 것을 보인다. Most of the 3D object reconstruction techniques divide the object into multiplane and approximate the surfaces of the object. The Marching Cubes Algorithm which initializes the mesh structure using a given isovalue, and Delaunay Tetrahedrisation are widely used. Deformable models are well-suited for general object reconstruction because they make little assumptions about the shape to recover and they can reconstruct objects from various types of datasets. In this paper, we propose a novel method for reconstruction of 3D objects. This method, for a 3D object composed of curved planes, compresses the 3D object based on the adaptive simplex-mesh technique. It changes the pre-defined mesh structure, so that it may approach to the original object. Also, we redefine the geometric characteristics such as curvatures. As results of simulations, we show reconstruction of the original object with high compression and concentration of vertices towards parts of high curvature in order to optimize the shape description.

과도한 운동으로 발생한 횡문근융해증에 의한 급성신부전증 1예

문철호,류보열,모성환,김태종,기장도,박용관,김용환,정종훈 조선대학교 1995 The Medical Journal of Chosun University Vol.20 No.1

Rhabdomyolysis may be defined as a clinical and laboratory syndrome which releases muscle cell contents into the plasma, such as creatine phosphokinase, due to skeletal muscle injuries. It can be the result of many diverse causes including muscle disease, ischemia, genetic disorder, metabolic disorder, infectious disease, drugs, comatose state, trauma or vigorous exercise that can lead to acute renal failure as a complication. Since first reported in 1941, rhabdomyolysis-induced acute renal failure has been documented many times, and the major causes of this disease are carbon monoxide poisoning, snake bites, and etc in Korea Reports of acute renal failure after exercise-related rhabdomyolysis with myoglobinemia are rare. We report a case of acute renal failure caused by exercise-related rhabdomyolysis in a 20 year old man.

아데닌과 디에톡시메틸 아세이트의 반응에 대하여

문성훈,심현관 釜山水産大學校 1984 釜山水産大學 硏究報告 Vol.24 No.2

In order to obtain 6-(ethoxymethyleneamino) purine, which is a useful intermediate for the synthesis of 6-substituted aminopurine, the reaction of adenine with diethoxymethyl acetate was attempted. The product was analyzed by thin layer chromatography and it was found that the product was apt to be converted to side products slowly. Separation of the product was carried out by silica gel column chromatography. By the reason of substitution with methanol which is used as chromatographic solvent, 6-(methoxymethyleneamino) purine was obtained. The product was identified by FT-NMR, UV, and IR Spectroscopic studies, and then it was found that the product was composed of syn-and anti-isomers as a mixture.

전경대원에서 발생한 결핵의 임상 양상

문창기,박상준,조민구,김영중,김소연,김윤권,정준오,안석진,김은실,서승오,김지훈,최원제,이윤영,박형기,최규영,김현근 대한감염학회 2006 감염과 화학요법 Vol.38 No.6

Background: The purpose of this study was to document the incidence and clinical characteristics of patients with tuberculosis (TB) in combat and auxiliary police, living in a group, in Korea where the incidence rate of active TB in a general population is higher than in Western countries. Materials and Methods:We retrospectively reviewed the medical records of all tuberculosis patients diagnosed at National Police Hospital from January 2002 through December 2004. Results:In 2002-2004, a total of 156 cases of tuberculosis were identified with the mean (Standard deviation) age of 20.6 (±1.0) years. Of these, 134 (85.9%) patients were registered as new cases, 11 (7.1%) as relapse, 2 (1.3%) as failure, 5 (3.1%) as treatment-after-default cases whereas 4 (2.6 %) patients were not included in any categories. Average annual new TB rate and smear-positive TB rate were 86.5/10^(5) and 17.4/10^(5) person-years, respectively. In 12 of 31 smear-positive cases, time from onset of symptoms to diagnosis was more than 30 days. Two multidrug-resistance TB cases were identified and two suspected outbreak episodes of TB had occurred during 3 years. Conclusion:There was no statistically significant difference in the incidence rate of new cases of TB between the general population aged 20 to 29 years and combat and auxiliary police in Korea. 배경 : 국내 결핵의 발생은 감소 추세에 있으나 여전히 후진국형 발생양상을 보이고 있다. 특히 집단생활을 하는 젊은이들에서 발생하는 결핵의 유행이 간헐적으로 알려지고 있어 우려를 낳고 있다. 이에 저자들은 최근 전경대원의 결핵 발병 양상에 대해 알아보고자 본 연구를 시행하였다. 재료 및 방법 : 2002년 1월부터 2004년 12월까지 3년간 경찰병원에서 결핵 진료를 받은 전경대원의 의무기록을 후향적으로 분석하여 연도별 결핵 신환발생률, 도말양성결핵 신환율, 진단 지연, 집단발병, 다제내성결핵을 조사하였다. 결과 : 연도별 결핵 신환자 수(10만명당 발생추정치)는 2002년 50명(83.6명), 2003년 42명(83.7명), 2004년 42명(93.5명)이었고 도말양성 폐결핵 신환자 수는 2002년 10명(16.7명), 2003년 11명(21.9명), 2004년 6명(13.4명)이었다. 3년간 도말양성 폐결핵 환자는 31명이 있었고 그 중 12명은 호흡기 증상 발생 30일이 지나서 진단을 받았다. 다제내성 결핵은 2명이 있었으며 결핵의 집단발병이 의심되는 사례는 2차례 있었다. 결론 : 전경대원과 20-29세 연령군 일반인의 결핵 신환발생률, 도말양성 폐결핵 발생률의 통계적으로 유의한 차이는 없었다.

장간막의 염증성 근섬유모세포종 - 1예 보고 -

임성직,김교영,박재훈,김윤화,박용구,이주희,양문호 대한병리학회 1999 Journal of Pathology and Translational Medicine Vol.33 No.9