만성 위염전 2 례

박찬규,이동욱,남성진,김추성,조성래,구본천,박영재,허규찬 啓明大學校 醫科大學 1997 계명의대학술지 Vol.16 No.3

위염전은 위의 비정상적인 회전으로 생기는데 급성증에서는 진단이 늦어질 경우 치명적일 수도 있으나, 만성증의 경우는 비특이적 위장관 중상을 나타내며, 치료되지 않을 경우 수년 동안 증상이 지속될 수도 있다. 최근 저자들은 소화불량, 식후 상복부 동통을 주소로 내원한 환자에서 만성위염전 2 례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. Gastric volvulus is an abnormal rotation of the stomach. Gastric volvulus may present as an emergency or as a chronic condition. Acute volvulus si potentially lethal if unrecognized, while a chronic volvulus may cause symptoms for years if not treated. Gastric volvulus may be more common than previously estimated. Approximately 700 cases have thus far been documented. In patients with vague upper abdominal pain, bloating, vomiting, early satiety and weight loss, chronic gastric volvulus are reported and the related literature reviewed. The clinical presentation, diagnosis, and treatment are treatment are discussed. Features of acute and chronic volvulus are compared.

Three-Dimensional Porous Collagen/Chitosan Complex Sponge for Tissue Engineering

Kim, Sung Eun,Cho, Yong Woo,Kang, Eun Jung,Kwon, Ick Chan,Lee, Eunhee Bae,Kim, Jung Hyun,Chung, Hesson,Jeong, Seo Young The Korean Fiber Society 2001 Fibers and polymers Vol.2 No.2

A three-dimensional, porous collagen/chitosan complex sponge was prepared to closely simulate basic extracellular matrix (ECM) constitutes, collagen and glycosaminoglycan. The complex sponge was prepared by a lyophilization method and had the regular network with highly porous structure, suitable for cell adhesion and growth. The pores were well interconnected, and their distribution was fairly homogeneous. The complex sponge was crosslinked using 1-ethyl-3-(3-dimethyl aminopropyl) carbodiimide (EDC) and N-hydroxysuccinimide (NHS) to increase its boilogical stability and enhance its mechanical properties. The crosslinking medium has a great effect on the inner structure of the sponge. The homogeneous, porous structure of the sponge was remarkably collapsed in an aqueous crosslinking medium. However, the morphology of the sponge remained almost intact in a water/ethanol mixture crosslinking milieu. Mechanical properties of the collagen/chitosan sponge were significantly enhanced by EDC-mediated crosslinking. The potential of the sponge as a scaffold for tissue engineering was investigated using a Chinese hamster ovary cell (CHO-K1) line.

무우종자의 발아촉진에 관한 연구

조성희,성찬기 中央大學校 自然科學硏究所 1987 自然科學硏究所 論文集 Vol.1 No.-

The changes of some components in the cell and germination rate of Raphonus Sativus L. seeds that were treated with GA₃, KINETIN and NAA were observed. The results were follows: 1. The content of soluble protein was increased in homogenate and cytosolic fractions of GA₃, and KINETIN treated seeds compared with one of control. 2. The content of glucose was increased in homoginate and cytosoli fractions of GA₃and KINETIN treated seeds compared with one of control on the half and the first day. 3. The activity of trehalase was increased in homogenate and cytosolic fractions of seeds which treated with GA₃and KINETIN compared with one of control on the first day. 4. The ATPase did not changed in all fractions of the untreated and stimulant treated seeds, during germination stages. 5. The germination rate was remarkedly increased by continuous soak treatment of GA₃and KINETIN on the first and second days but in the case of NAA treatment, it was very smiliar to control.

각막굴절수술(라식) 환자에 대한 경향성 분석

성아영,김찬수,이석주,조수현 대불대학교 2002 論文集 Vol.8 No.1

Now a days, LASIK(laser in situ keratomileusis) surgical operation is enforced widely by method that is used to correct ametropia such as near-sightedness, far-sightedness, astigmatism etc. This wishes to solve troublesome matter for glasses and contact lens wearer that reform a part of corneal stroma by laser after using microkeratome in which make corneal flap. This experiment present that refraction by auto-refractometer in point of time before and after a week to those who undergone LASIK surgical operation 30 patients. 60 eyes that become full corrected(spherical power : +0.50D∼-0.50D). By this research method, in point of time that examination has a week after operation because of refraction power changed by passage of time and classified by sex, age, occupation, and degree of myopia(low:-1.0D∼-3.0D, moderate: -3.0D∼-6.0D, high :more than -6.0D). As a result of this study LASIK surgery can solve uncomfortableness by wearing glasses or contact lens, but the result objectively doesn't meet satisfaction level though full correction had made.

예혼합 난류유동장내 점화핵의 난류화염두께 및 난류화염속도의 예측

조성찬,문희장 한국항공대학교 항공우주산업기술연구소 2003 航空宇宙産業技術硏究所 硏究誌 Vol.13 No.-

The propagation of a flame front subjected in a given intensity of turbulent flow is numerically investigated using the presumed PDF methods. The main characteristics of a turbulent flame thickness is also calculated in order to capture the basic behavior of a turbulent flame. It was found that the proposed models can achieve the prediction of these fundamental properties of turbulent flame, and demonstrate the capacity of probability density function based statistical model. A spherical coordinate is used to simulate the on growing kernel characteristics at the early stage of spark event. The result shown for the turbulent flame thickness allowed us that this method have the potential and can be extended to low Damko¨hler number regime. A more concrete analysis is expected in the future with a more elaborated chemical reaction model.

요로감염이 진단되었거나 의심되는 영아에서 방광요관역류를 예측할 수 있는 임상적, 실험실적 지표들에 대한 연구

조승만,홍성완,홍찬의,정철주,노영일 朝鮮大學校 附設 醫學硏究所 2007 The Medical Journal of Chosun University Vol.32 No.3

Background: Vesicoureteral reflux (VUR) in infants may be the main cause of recurrent urinary tract infection (UTI) and renal scarring. So the early diagnosis of VUR is helpful to prevent recurrence of UTI and to alleviate the grade of VUR. This study is to examine the predictability of clinical and laboratory variables for VUR in infants with confirmed or suspected UTI. Material and Methods: Data of infants younger than 12 months who underwent voiding cystourethrography (VCUG) between 2003 and 2006 were evaluated retrospectively. Among the infants with suspected UTI, infants with VUR (Group 1) vs no VUR (Group 2) were compared. And among the Infants with confirmed UTI, infants with VUR (Group 3) vs no VUR (Group 4) were compared, Variables selected in this study were age at onset, gender, fever, laboratory data and imaging (ultrasonography). Results: Among the variables, the mean of C-reactive protein (CRP) in Group 1 and Group 2 were 5.24±6.82 and 2.46±3.75, respectively, showing that Group 1 had a higher value than Group 2 (P=0.0104). And the number of patients with fever □38.5℃ in Group 1 was higher than in Group 2 (U=0.0004). The mean of C-reactive protein (CRP) in Group 3 and Group 4 were 8.95±6.1 and 5.39±6.0, respectively, showing that Group 3 had a higher value than Group 4 (P=0.0409). Conclusion: Fever≥38.5℃ and CRP≥0.6 ㎎/dL were closely associated with VUR in infants with suspected UTI. And CRP□3.4㎎/dL was closely associated with VUR in infants with confirmed UTI. However, further evaluations and studies for these variables will be needed to use them as predictors for VUR.

산발성 장형 위선암 환자의 Microsatellite Instability와 병리학적 양상

조창희,홍유찬,안지현,최경현,이상호,신영명,윤기영,정민정,장희경 고신대학교의과대학 2007 고신대학교 의과대학 학술지 Vol.22 No.2

Background : Through many researches, microsatellite is expected to be a good diagnositic and prognostic factor in colorectal cancer, endometrial cancer, gastric cancer, and the others. The prevalence of microsatellite instability (MSI) in gastric carcinoma has reported variously, 13~44%. Purpose : We aimed to determine the prevalence of MSI-high and the relationship between MSI and pathological characteristics of sporadic intestinal type adenocarcinoma of stomach. Material and Methods : We analyzed 106 sporadic intestinal type adenocarcinoma specimens excised from patients who were over thirty-five years old to determine the statue of microsatellite by DNA sequencing. The tissues were formalin-fixed and paraffin embedded. DNA were extracted and amplified by polymerase chain reaction (PCR). MSI was determined using five markers recommended by National Cancer Institute (NCI). Specimens were also studied with five patholical factors-differenciation of tumor cells, depth of invasion, lymph node metastasis, vessel invasion, and perineural invasion- to determine pathological state. Result : The microsatellite statue was determined as MSI-High in 5 cases (4.7%), no MSI-low, and MSS (microsatellite stable) in 101 cases (95.3%). Within the frequency, there was no large gap in the distinction of gender in MSI cases, but in MSS cases, there was three-times more cases in male. MSI cases had moderate-to-poor differenciation and trend to invade toward serosa. All MSI cases showed no perineural invasion. But we could not find any statistical significance between MSI and pathological characteristics of sporadic intestinal type adenocarcinoma. Conclusion : Results suggest that MSI can not make any certain pathological significance in sporadic intestinal type adenocarcinoma. Even though less than 5% of sporadic intestinal type adenocarcinoma patients showed MSI, it can be used as a influential prediagnostic factor of gastric cancer. Further study with large scale of cases will be followed to verify these results.

MSGC형 센서를 위한 제어시스템 및 영상 획득 S/W 개발

조진호,진경찬,채승표,박영식,김명남 경북대학교 센서기술연구소 1997 연차보고서 Vol.1997 No.-

강남성모병원에서의 정신과 자문경험

조용찬,이성필,유태열 大韓神經精神醫學會 1984 신경정신의학 Vol.23 No.2

In an attempt to evaluate the current trends of psychiatric consultation, authors investigated 142 cases of in patients who were referred for psychiatric consultation at Kangnam St. Mary's Hospital from April 1, to November 30, 1983. The results were as follows: 1. The majority of consultations was requested from the department of internal medicine(67.61%). 2. The overall consultation rate was 1.71% of total inpatients for the time period. The department of internal medicine ranked highest in the consultation rate(5.12%). 3. Among the immediate reasons for psychiatric consultation, request for diagnostic evaluation and treatment was 65.63% and request for control of specific symptoms or behavior was 34.37%. 4. Among the somatic symptoms present on consultation, gastrointestinal symptoms and head & CNS symptoms were the most frequent ones. 5. Affective disorders including depression(25.39%), and organic mental disorder(16.58%) were the most frequent diagnostic impressions given by consultant. 6. Regarding the concordance rate with the recommendations given by consultant, absolute concordance with laboratory tests(including psychological tests), drug treatment and psychotherapeutic approach was observed among 62.39% of total consultees. However, non-concordance was observed among 11.93%. 7. For the discharge diagnosis, psychiatric diagnosis was given to 33.03% among all the consultees. 8. The inter-departmental transfer rate following psychiatric consultation was 21.20%.

산포도와 머루중의 Polyphenol Oxidase에 관한 연구¹

성찬기,박희중,임흥빈,조성희 中央大學校 基礎科學硏究所 1997 基礎科學硏究所 論文集 Vol.11 No.-

Polyphenol oxidase was partially purified from fresh vitis flexuosa and vitis amurensis and its characteristics were studied. the experimental results were summarized as follows. 1.The enzyme activities were increased during the fruit developement gradually in two sample. 2.The optimum pH and temperature for activity were 5.5 and 30℃, respectively. 3.The enzyme was active with o-phenols and trihydroxyphenol, but inactive toward m-diphenols and monophenols. 4.The ?? value of the enzymes was 15.4 mM in vitis flexuosa and 12.5 mM in vitis amurensis with catechol as substrate. 5.Inhibitors sudies indicated that sodium diethyl-dithiocarbamate, L-cysteine, sodium bisulfite, L-ascorbic acid and 2-mercaptoeyhanol were the most potent. 6.The enzyme activity increament by ?? was much better than those by the other metal ions.