생태계서비스 기반 국립공원 생태복지 개념정립 및 정책방향 설정

박은하 ( Eun Ha Park ),최수정 ( Su Jung Choi ),오충현 ( Choong Hyeon Oh ),정부희 ( Boo Hee Jung ),이나연 ( Na Yeon Lee ) 한국환경생태학회 2016 한국환경생태학회지 Vol.30 No.2

생태복지는 인간의 복지와 건강한 생태계의 상호관계성에 대한 국제적 담론에서 시작되었다. 본 연구는 국립공원이 생태복지의 최대 실현가능 지역이라는 점에서 국립공원에 적합한 ‘국립공원 생태복지’ 개념을 정립하고 정책방향을 설정함으로써 향후 국립공원에서의 생태복지 실현을 도모하기 위한 기초자료를 제공하는데 그 목적이 있다. 이를 위해 사전워크숍과 총 2회에 걸친 델파이 조사를 수행하였다. 본 연구를 통해 ‘국립공원 생태복지’는 국립공원에서 생태계의 지속가능성과 생물다양성을 유지하며, ‘국립공원 인간복지’와 ‘국립공원 생태계복지’의 조화를 지향하는 복지로 정의되었다. 2차 델파이 결과 모든 항목에서 평균 4.00 이상, 내용 타당도(CVR) 0.37 이상, 변이계수(CV)0.5 미만으로 타당한 내용으로 확인되었다. 국립공원 생태복지의 정책방향을 설정하기 위해 생태복지의 바탕이 되는 생태계서비스의 요소들 중 국립공원에 적합한 주요 요소를 도출한 결과 공급서비스에서 먹이·식량, 물, 유전자원 3항목, 조절서비스와 기반(서식지)서비스의 모든 항목, 문화서비스에서 미적정보, 휴양관광, 심신치유, 지식체계ㆍ교육적가치 4항목이 최종 도출되었다. 또한 본 연구에서는 국립공원 생태복지의 개념과 향후 국립공원 생태복지 정책이 어떻게 나아가야할지 방향성을 제시하였다. 그러나 이를 실현하기 위해서는 향후 이에 대한 구체적인 단위사업에 대한 실행계획이 수반되어야 하며 이를 위한 추가적인 연구가 필요할 것이다. The concept of Eco-welfare emerged in the process of discovering the relationship between a healthy ecosystem and human wellbeing. The objective of this study is to offer basic data for eco-welfare policy realization by conceptualizing the ‘National Park Eco-welfare’ since national parks are appropriate places for eco-welfare to be optimally implemented. A pre-workshop and two rounds of Delphi surveys were conducted to determine the concept of the ‘National Park Eco-welfare ’ and the main elements to be included in ecosystem service. Through this study, the concept of ‘National Park Eco-welfare’ was defined as efforts to conserve the biodiversity and sustainability of the ecosystem and create harmony between ‘National Park Ecosystem Welfare’ and ‘National Park Human Welfare’. To establish the direction of the National Park Eco-welfare policy, we identified the main elements of ecosystem services which are appropriate for the National Park. These are comprised of 3 elements (food, fresh water and genetic resources) from supply service, all elements from regulating service and supporting/habitat service and 4 elements (aesthetic information, recreation-based ecotourism, healing, and knowledge systems with educational values) from culture service. In this study, the concept of National Park Eco-welfare was established, and its policy objectives and scope were suggested. However, further studies are necessary to develop action plans areand thereby realize the policy.

로봇주차장 차량 입고장에서 차량의 비정렬 상태 추정 방법

엄수홍(Su-Hong Eom),박나연(Na-Yeon Park),류중현(Jung-Hwun You),이응혁(Eung-Huck Lee) 대한전자공학회 2021 대한전자공학회 학술대회 Vol.2021 No.6

This paper proposes a method to estimate state of a car which is parked crooked in a system which is using linear rail actuators of 2-axes in order to measure information of a car that a robot of the robot parking lots makes be parked. The method is to estimate if the car is parked crooked based on the distance between the car measuring system and the center of the wheels which are the front and back of the car on conditions that the system have the information respecting the center of each the front/back wheels. The proposed method that can estimate if the car is parked crooked is quantitatively verified, with 98% accuracy.

Protein kinase A-induced phosphorylation at the Thr154 affects stability of DJ-1

Ko, Yeon Uk,Kim, Su-Jeong,Lee, Juhyung,Song, Min-Young,Park, Kang-Sik,Park, Jun Bae,Cho, Hyun-Soo,Oh, Young J. Elsevier 2019 Parkinsonism & related disorders Vol.66 No.-

<P><B>Abstract</B></P> <P><B>Introduction</B></P> <P>Most cases of Parkinson's disease (PD) are sporadic, but genetic variations have been discovered in PD patients. PARK7/DJ-1 is a known cause of early-onset autosomal-recessive PD and is implicated in neuroprotection against oxidative stress. Although several post-translational modifications of DJ-1 have been proposed, phospho-modification of DJ-1 and its functional consequences have been less studied.</P> <P><B>Methods</B></P> <P>Putative phosphorylation sites of DJ-1 were determined by liquid chromatography-tandem mass spectrometry (LC-MS/MS analysis). Subsequently, phosphorylation site of DJ-1 was confirmed by <I>in vitro</I> kinase assay and cell-based pull-down assay. Impaired dimer formation of phospho-null mutant was measured using DSS crosslinking assay and immunoprecipitation assay. To evaluate physiological consequences of this event, protein stability of DJ-1 WT and DJ-1 phospho-null mutant were compared using cycloheximide chase assay and ubiquitination assay.</P> <P><B>Results</B></P> <P>Here, we showed that DJ-1 directly bound to the catalytic subunit of protein kinase A (PKAcα). We found that PKAcα is responsible for phosphorylation of DJ-1 at the T154 residue. Interestingly, dimerization of DJ-1 was not detected in a DJ-1 T154A mutant. Furthermore, stability of the DJ-1 T154A mutant was dramatically reduced compared with that of wild-type DJ-1. We found that DJ-1 T154A was prone to degradation by the ubiquitin proteasome system (UPS).</P> <P><B>Conclusion</B></P> <P>We identified a novel phosphorylation site of DJ-1. Furthermore, we determined protein kinase A that is responsible for this posttranslational modification. Finally, we demonstrated physiological consequences of this event focusing on dimerization and protein stability of DJ-1.</P> <P><B>Highlights</B></P> <P> <UL> <LI> PKAcα phosphorylates PARK7/DJ1 at the Thr154 residue. </LI> <LI> Disruption of Thr154 phosphorylation is linked to a lower stability. </LI> </UL> </P>

천안지역 일부 다중이용시설의 포름알데히드 농도에 관한 연구

전혜리(Hye-li Jeon),조수연(Su-yeon Jo),조혜란(Hye-ran Jo),조태진(Tae-Jjn Cho),박종안(Jong-an Park),손부순(Bu-soon Son) 대한환경위생공학회 2009 대한환경위생공학회지 Vol.24 No.2

This study was conducted at a Terminal, a Parking Lot, an Underground shopping center, a Funeral hall and a Hospital waiting room of Cheon An area in August 2008 to examine the concentration level of HCHO(formaldehyde). The concentration level of the remodeled sites were 39.4 ± 12.0 ㎍/㎥ in the terminal, 32.7 ± 7.3 ㎍/㎥ in the parking, and 97.8 ± 29.4 ㎍/㎥ in the underground shopping center. The underground shopping center had the highest level and followed by the terminal and the parking. On the contrary, the site remodeling had the level of 17.7 ± 12.4 ㎍/㎥ in the funeral hall and 17.9 ± 0.6 ㎍/㎥ in the hospital waiting room. The funeral hall had highest level than that of the hospital waiting room. Both the remodeled sites and the not remodeled site had concentration level of HCHO below the standard level, but it was higher in the remodeled sites. There were no relations among the HCHO, the temperature and the humidity in facilities of Cheon An area.

농업소득 안정화을 위한 직접지불제 도입 방안

박진도,황연수 東亞大學校生命資源科學大學附設 農業資原硏究所 1996 農業生命資援硏究 Vol.5 No.1

Farm price and income instability will reemerge as a major problem of agriculture in the post Uruguay Round period. The Korean government attempts to introduce the various types of direct payment allowed by WTO, and the farm income stabilization program is one of those. The objective of this study is to examine necessities for and devices of farm income stabilization program. The major findings of the study are summarized as follows: 1. Considering Agreement on Agriculture of UR, foreign examples and characteristics of korean agriculture, it is desirable to introduce a whole-farm income stabilization program like Canadian NISA(Net Income Stabilization Account) rather than programs by commodity. 2. The farm income stabilization program recommended in this study is a voluntary program that helps producers save money in good times to stabilize their incomes when farm revenues drop. In the program, producers deposit funds(1.5% of gross receipts) into their own account and receive a matching contribution(3% of gross receipts) from the government. 3. By introducing this program, stabilization and support of the farm income, increase of food production and maintenance of regional society are expected. Opinion survey showed that 80 percent of regional experts were in favor of this program. 4. The problems to be solved in the process of the program include conflicts with other programs, low participation rate of farmers, moral hazard in investigating eligible gross receipts, and administrative and technical difficulties.

동일한 국제예후지표(International Prognostic Index)를 나타내는 미만성 대형 B-세포 림프종에서 Bcl-2와 p16의 임상적 중요성

박상은,박수진,곽승근,박남숙,천재민,윤환중,조덕연,김삼용,김진만 충남대학교 의학연구소 2003 충남의대잡지 Vol.30 No.2

In Korea, malignant lymphoma is a common cancer, comprising about 2.7% of all malignant neoplasm. Diffuse large B cell lymphoma is the most common lymphoma, representing about 50% of all Non-Hodgkin's lymphoma. Diffuse large B-cell lymphoma is usually considered as heterogeneous group of neoplasms rather than a single clinicopathological entity. Clinical prognostic systems, including the International Prognostic Index (IPI), although useful to assess overall prognosis, embrace patients with heterogeneous prognoses. But International Prognostic Index scoring system is not sufficiently predict the prognosis. It is likely that the prognostic assessment of patients with diffuse large B-cell lymphomamight be improved by using biological features. Bcl-2 protein and p16 protein expression is recognized as useful biologic markers predicting the prognosis of patients with diffuse large B-cell lymphoma. To determine the clinical significance and prognostic value of bcl-2 and p16 proteins expression patterns, we studied 18 patients with de novo DLBL, whose archival pathology specimen were available for immunohistochemistry studies, atChungnam National University Hospital from September 1992 to December 2000. Archival specimens from each patient were immunostained with respective antibodies for bcl-2, p16. The results are as follows; 1) The median age was 54(rage : 37-69). There were 12 male patients(66.7%) and 6 female patients(33.3%) The 'B' symptom was abscentin all patients. The stages were as follows : Ⅰ, 2 patient(11.1%), Ⅱ, 10 patient(55.6%), Ⅲ, 4patient(22.2%) and Ⅳ, 2patient(11.1%). 3 patients(16.8%) had the elevated LDH level, 14 patients(77.8%) had the normal LDH level and 1 patients(5.6%) was not identified the LDH level. 2 patients(11.1%) had the bulky disease and 16 patients(88.7%) had no bulky diease. The distribution of ECOG status were O, 2 patients(11.1%c), 1, 14patients(77.8%) and 2, 2patients(11.1%). 2) Theimmunohistochemistry results are as follows bcl-2:+,10 patients(55.6%), bcl-2:-, 8patinets(44.4%), p16:+,3 patients(16.7%), p16:-, 15patients(83.3%) 3) After a median follow UP durations of 67 months, the median survival time was 57 months with a rage of 7-100+ months. 5-years overall survival rates was 44% by Kaplan-Meier method. 4) Reduced overall survival was demonstrated in the patients who expressed bcl-2 protein(P=0.0174). 5-year overall survivial rate was 12%(bcl-2 expression) versus 88%(no bcl-2 expression) 5) Among diffuse large B-cell lymphoma patients with IPI score 0-1, reduced overall survival was demonstrated with bcl-2 expression(P=0.023). 5-year overall survival rate was 18%(bcl-2 expression group) versus 100%(no bcl-2 expressiongroup) 6) Median survival durtation of diffuse large B-cell lymphoma patients negative for p16 expression was 57 months whereas p16 postive patients' median survival duration was not reached(P=0.4478). In diffuse large B-cell lymphoma patients with identical IPI scores, bcl-2 expression had additional prognostic value.

미다졸람의 비강 내 추가투여가 소아의 경구 진정요법에 미치는 영향

장수영,김지연,박기태 大韓小兒齒科學會 2012 大韓小兒齒科學會誌 Vol.39 No.1

Effect of supplementary intranasal midazolam on oral sedation of children The purpose of this study was to compare the cardiopulmonary parameters of two sedation regimens during dental treatment: (1) Oral chloral hydrate(CH) and hydroxyzine(HZ) with nitrous oxide-oxygen(N2O/O2) inhalation( CH-HZ group); (2) Oral chloral hydrate(CH) and hydroxyzine(HZ) with nitrous oxide-oxygen(N2O/O2) inhalation and supplementary intranasal(IN) midazolam administration(MIDA group). Among the patients of OO hospital who received dental treatment under sedation over the past 5 years, 44 patients were selected for each group of CH-HZ and MIDA according to their age, gender and weight. Following parameters that were recorded every 5 minutes were compared: 1) Heart rate(HR) 2) O2 saturation 3) End tidal carbon dioxide concentration(EtCO2) 4) Respiratory rate(RR) 33 patients of Group MIDA who have complete data of 15 minutes before and after supplementary IN midazolam administration were selected. And measurements 15 minutes before and after midazolam administration in same patient were evaluated. The results were as follows: 1. Heart rate was significantly higher in MIDA group than in CH-HZ group, but it was within normal range. 2. Comparing HR, O2 saturation, EtCO2, RR between before and after of supplementary IN midazolam administration in the same patient, the differences were not statistically significant. 이 연구는 소아환자의 경구 진정요법 시 미다졸람의 비강 내 추가 투여가 심폐기능에 미치는 영향을 알아보기 위한 것으로 5 년간 삼성서울병원 소아치과에서 chloral hydrate와 hydroxyzine을 경구투여하고 N2O/O2 inhalation을 추가로 사용한 진정요법으로 치료 받은 환자 중 미다졸람을 추가투여 받은 실험군(MIDA군)과, 미다졸람을 추가 투여하지 않은 대조군 (CH-HZ군)을 각각 44명씩 선정하여 서로 비교하였다. 진정요법 중 5분마다 측정된 1) Heart rate(HR) 2) O2 saturation 3) End tidal carbon dioxide concentration (EtCO2), 4) Respiratory rate(RR)의 평균값을 비교하였다. 또한 동일 환자에서의 미다졸람 투여 전 후의 심폐기능지표의 변화 양상을 평가하기 위해 MIDA군 중에서 미다졸람 투여 전 후 15분 이상의 기록이 존재하는 33명을 선정하여 미다졸람 투여 전 후 15분 시점의 측정값을 각각 비교하였다. 결과는 다음과 같다. 1. Heart rate는 미다졸람을 추가 투여한 군에서 유의하게 높았으며 나머지 심폐기능 지표의 측정값들은 차이가 없었다. 두 군의 측정값들은 모두 정상범위 안에 있었다. 2. 동일 환자에서 미다졸람 투여 전 후 15분의 측정값을 비교한 결과 두 시점간에 측정된 값들은 유의한 차이가 없었다.

췌십이지장절제술 후 발생한 지속적인 구토증과 Wernicke 뇌병증

박우영,김성완,이삼연,신일선,김재민,박기형,양수진,윤진상 大韓神經精神醫學會 2007 신경정신의학 Vol.46 No.3

Wernicke encephalopathy is an acute neurologic disorder attributable to thiamine (vitamin B1) deficiency. We report the case of a 61-year-old female patient who presented Wernicke encephalopathy after surgery for pancreatic head cancer. From the ninth postoperative day, she had suffered from nausea and vomiting and had difficulties ingesting food, she was given total parenteral nutrition (TPN), but lacked adequate vitamin (thiamine) supplementation. After 28 days, she developed ataxia, ophthalmoplegia, and mental confusion. The magnetic resonance image showed pathologic changes in the medial thalamus,periaqueductal gray matter, medulla and mamillary bodies. The blood level of thiamine was very low. After intravenous and oral supplementation of thiamine (200 mg/day), consciousness was soon normalized and neurologic symptoms have gradually been improving. Nausea and vomiting disappeared after administration of a low dose of mirtazapine (7.5 mg/day). We emphasize the importance of thiamine supplementation to the patients who suffer from vomiting which hinders them from taking food and who require prolonged TPN.

꿀벌부채명나방 유충으로부터 Xanthomonas maltophilia의 분리 및 동정

박선호,유연수 계명대학교 산업기술연구소 1998 産業技術硏究所 論文報告集 Vol.21 No.1

A symbiotic bacteria associated with Galleria mellonella larva was isolated and identified as Xanthomonas maltophilia sp. by using the BioLog Automated Microbial Identification System. Also three other strains of bacteria were isolated from Galleria mellonella larvae and identified as CDC group DF-3, Enterobacter agglomerans biogroup 5, and Serratia marcescens sp., respectively. Several biochemical and physiological tests were performed to determine the strain characters. X. maltophilia did not adsorb neutral red of bromothymol blue and grew below 37℃. Xanthomonas maltophilia and three other strains were pathogenic against the insect host when they were injected into hemolymph of the insect. X. maltophilia was rod-shaped and its cell size was ranged from 1㎛ to 2㎛.

활동이론의 관점에서 바라본 박물관, 커뮤니케이션, 그리고 학습

박지연,이수민,이병준 한국문화교육학회 2011 문화예술교육연구 Vol.6 No.4

Museum is a medium which communicates with previous generation's experiential memories and present generation's cultural memories. Therefore, the communication is a core task in museum. Museum needs mediums like exhibition and education and we have to discuss how to structuralize these things. The museum communication could be explained through the Cultural-Historical Activity Theory(CHAT). The CHAT has been developed by several theorists like Vygotsky. Especially, the third generation's CHAT has been developing by Engeström. It is a worthy theoretical structure that can show museum as a messenger of communication in society and its communication problems. This study is based on the CHAT and analyzes museum in a social activity system and activity system in a museum from micro/macro-scopic view. Also, it produces practical models that connect museum with community art field and museum with schools. 박물관은 앞선 세대의 체험적 기억을 현 세대에게 문화적 기억의 형태로 커뮤니케이션하는 매개체이다. 따라서 박물관에서 소통(communication)이라는 개념은 핵심적인 과제일수 밖에 없다. 박물관은 그 자체로 전시와 교육과 같은 매체(medium)를 필요로 하며 이를 어떻게 구조화할 것인가의 문제가 박물관커뮤니케이션의 측면에서 논의될 필요가 있다. 이러한 거시적, 미시적 차원의 박물관커뮤니케이션의 과제는 비고츠키와 여러 이론가들의 연구성과를 정리하고 발전시킨 활동이론에 의해 잘 설명될 수 있을 것으로 보인다. 특히 Y. Engeström에 의해 발전된 제3세대 활동이론은 사회속에서의 커뮤니케이션의 전달자로서의 박물관과 박물관내에서의 커뮤니케이션의 문제를 잘 드러낼 수 있는 이론체계라고 생각된다. 본 연구는 활동이론에 근거하여 거시적·미시적 관점에서 사회활동시스템 속에서의 박물관과 박물관 내에서의 활동시스템을 분석하고 이를 통해 박물관의 커뮤니케이션을 박물관 내부 활동시스템 간의 네트워크 실천, 박물관과 지역의 예술장(藝術場)이 연계된 네트워크 실천과 박물관과 학교가 연계된 네트워크 실천 모형을 구조화하여 제시하려 한다.