백서 척수후근절로부터 슈반세포의 효과적인 체외 배양법

김성민,이종호,김남열,안강민,최원재,최시호,차미주,이주영,황순정,장정원,명훈,최진영,서병무,정필훈,김명진 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.4

Schwann cells(SCs), an important component of the peripheral nervous system, intract with nerous to mutually support growth and replication for the peripheral nerve regentation. Recently, ading SCs to the lumen of guidance channel is widely tried to improve regeneration or to make regeneration possible over otherwise irreparable gaps. however, it is not easy to isolate and multiplicate SCs as much as enough to help the axonal regeneration. For the allogeneic SCs source for tubular nerve guidance, we developed a little bit improved technique of harvesting and multiplicating SCs. by culturing dispersed dorsal root ganglia in specially designed medium with growth factors and serial processing, we repeatedlly generate relatively homogenous SC cultures. Our technique was compared with other methods of literature using immunostaining methods such as GFAP, S100, BDNF and the total SC count assessment at different time interval after primary culture.

악안면성형수술을 받은 환자에 있어서 수술 결과를 증진시킬 수 있는 화장법

김지혁,김성민,박영욱 大韓顎顔面成形再建外科學會 2001 Maxillofacial Plastic Reconstructive Surgery Vol.23 No.6

The importance of desire that human want to beautify their face and body has been increased as the cultural and social economy has been developing. Human being has made every efforts to satisfy this desire, currently plastic surgery by which one could highlight one's characteristics or hide one's weak points has been generalized, also the surgical technique has been developed steadily to keep trace with the social demand. But those kinds of surgery have a few problems yet; one is that we cannot predict the postoperative appearances exactly, the other, unavoidable facial scars might be produced. Since make-up technique and cosmetics have also been developed with social development, make-up art that could create one's own charming points and lessen one's weak points to some degree is developed and also modified to lead to create 'corrective make-up' for facial contour, which becomes currently popularized. Conclusively, we try to consider a specialized make-up technique for the patients taken maxillofacial plastic surgery to improve the postoperative results with literature review.

患者에서 分離한 腸內細菌(大腸菌)에 대한 血淸型 및 抗生劑 耐性傳達에 관한 硏究

김승곤,최성민 서울保健大學 1994 論文集 Vol.14 No.1

This study was undertaken the biochemical characteristics, serotyping and antibiotics susceptibility to 79 strans of Escherichia coli isolated from patient from march in 1993 to December in 1993. Of 79 isolates, thirty one isolates(39.2%) were idenfied by pathogenic E. coli immune sera producted by Denka Seiken. Among them, 9 isolates(11.4%) were 06, followed by 015 and 044(4 isolates, 12.9%), respectively. 018, 0114, 0119, 0125, 0146, 0153 and 0164 were identified 1 isolate(3.2%), repectively. Resistance rate of E. coli isolated from patients against 12 antibiotics were 86.1%(68 isolates). Of them, resistance rate against TC was 68.3%(54 isolates), AM 64.4%(51 isolates), CB 62.0%(49 isolates), NN and NA 8.9%(7 isolates) and PB 1.3%(1 isolate), respectively. Of 68 resistant isolates, 59 isolates(86.8%) were resistant to more than 2 drug, followed by 2 drugs-resistance pattern01 isolates, 16.2%), 3 drug and 6 drig resistance pattern(9 isolates, 13.2%). Of multipleresistance pattern, AM-CB-SM and AM-CB-SM-TE pattern were most frequent(5 isolates, 7.4%, respectively) and more than 10 drugs resistance pattern was 1 isolate. Of 68 resistant isolates, 42(61.8%) were transferred their resistance to recipient cell (E. coli ML1410Na^(r)), Of them, the most frequently multiple transferred drugs was 2 drugs(40.5%, 17isolates) and the most frequently multiple transferred pattren was AM-CB(23.8%. 10 isolates).

암 병동 간호사의 통증관리에 대한 지식과 태도

공성화,방찌야,서민숙,현신숙,김희정,이미애1,이미애2,유현희,허재경,김은애,박경숙 성인간호학회 2004 성인간호학회지 Vol.16 No.1

Purpose: The purpose of this study is to evaluate the knowledge and attitudes of oncology ward nurses toward cancer pain management and to find ways to improve the educational program for nurses. Method: A total of 209 nurses working at the oncology ward of three hospitals in Seoul and a Gyenggi Province. The survey instrument used was the 32-item scale for evaluating nurses knowledge and attitudes originally developed by McCaffery and Ferrell'(1990). that was by Kim'(1997). Result: In terms of the nurses knowledge of pain management. the result showed that the nurses scored an average of 67.8 out of 100 for phamacokinetics of opioids. 84.8 for classification of analgesics, 60.1 for pain assessment, and 70.7 for drug administration. 18.2% of the nurses hesitate to inject the narcotic agent because of concerns regarding the drug's potential side effects. there was significant difference in the knowledge of pain management according to the general characteristics of pain in terms of the nurses age(p=.001), position (p=.016). years of experiences(p=.002), experience of cancer pain education(p= .001). Conclusion: The also showed that nurses working at cancer ward lack knowledge. It is important to provide intensive education to nurses about cancer pain management.

깊이우선 검색을 이용한 논리 추출 알고리즘

강민섭,임권묵,김성원 안양대학교 자연과학연구소 1995 自然科學硏究 Vol.2 No.-

본 논문은 깊이우선 검색(depth first search)을 이용하여 CMOSVLSI 회로로 부터 등가 논리레벨의 회로로 변환하는 효율적인 논리 추출 알고리듬에 관한것이다. 제안하는 방법에 있어서 논리 추출은 두 단계의 절차에 의해서 수행된다. 우선 트랜지스터 레벨의 회로를 인접 그래프(adjacent graph)로 변환하고, 논리회로를 구성하는 가장 기본적인 논리기능(logic function) 블럭으로 나눈다. 다음에 각각의 기능 블럭을 직병렬 그래프(series-parallel graph)로 표현하여 직병렬 분해(series-parall reduction)를 수행한 후, 동형성(isomorphic) 판정 과정을 거쳐서 게이트 레벨의 회로를 추출한다. This paper describes about an efficient logic extraction algorithm based on the depth first search which can extract gate-level logic description from CMOS transistor level description. The proposed heuristic series-parallel reduction algorithm extracts primitive logic gates from the given series-parallel graph. The time complexity for performing this algorithm requirs O(m + n), where m and n represent edge and node of the given graph.

Caffeic Acid의 ONOO^(-) 제거활성

이지영,성도유,노재경,김유정,제정환,김민선,최재수,정해영,이경희 대한암예방학회 2003 Journal of cancer prevention Vol.8 No.3

구강악안면외과에서 의식하진정에 필요한 Midazolam용량에 관한 연구

장재현,김성민,김소희,박영욱 대한악안면성형재건외과학회 2002 Maxillofacial Plastic Reconstructive Surgery Vol.24 No.3

Conscious sedation is a minimally depressed level of consciousness that retains the patients' ability to maintain the airway continuously and to respond appropriately to physical stimulation and verbal command at any time, produced by a pharmacologic or nonpharmacologic method or a combination thereof. In dental anesthesia, a state of sedation in which the conscious patient is rendered free of fear, apprehension and anxiety through the use of pharmacologic agents. Midazolam is a useful drug of benzodiazepine on minor operation of dentistry. The purpose of this study is to estimate the appropriate dosage protocol of Midazolam to the patient receiving intravenous sedation at the department of oral and maxillofacial surgery. Total subject was fifty-one patients and fifteen patients of this subject were decided to control group that they were not received intravenous sedation. The experimental group was randomly subdivided into two groups and each of those groups was administrated to 0.05 ㎎/㎏ and 0.08 ㎎/㎏ each other. All patients of the subject were surveyed with postoperative one day questionaire to evaluate the level of sedation. We found that the result was statistically significant between the experimental and the control, and so we present the protocol of the department of oral and maxillofacial surgery, Kangnung National University Dental Hospital.

비복신경이식을 이용한 긴 거리의 말초신경 결손부 수복

이종호,이세영,김명진,이은진,안강민,김성민,최원재,명훈,황순정,서병무,최진영,정필훈 大韓顎顔面成形再建外科學會 2003 Maxillofacial Plastic Reconstructive Surgery Vol.25 No.2

The surgery of oral and maxillofacial area poses the risk of cranial nerve damage such as trigeminal nerve or facial nerve. Inferior alveolar nerve is prone to damage in the third molar extraction, implant installation, orthognathic surgery, open reduction and rigid fixation, and tumor ablation surgery. On the other hands,facial nerve is likely to be damaged or sacrificed with trauma or parotidectomy. In case of inferior alveolar nerve injury, the incidence is reported to be about 1.3%. The nerve function will almost recover in minimal damage, but it won't recover at last in total damage of a part of nerve unit. In latter cases, nerve regeneration in intended by allograft as nerve substitute or various route of merve condit. But the recovery with autograft is believed to be most relialbe mrthod in the rapair of long-span(longer than 15㎜)nerve defect. We have performed autologous sural nerve graft in the repair of nerve defect, which is caused by resection of benign or malignant tumor. Hereby we report the method of nerve harvesting, recovery of defected peripheral nerve and the complications of donor site with the discussion of sural nerve anatomy.

Lithium-Pilocarpine으로 유발된 중첩경련 흰쥐 모델에서 Ketamine의 항경련 및 신경 보호 효과

고석범,박성경,손영민,김영인 대한간질학회 2004 대한간질학회지 Vol.8 No.1

단방성 법랑모세포증 환아에 대한 증례 보고

최서정,박호원,김성민 大韓小兒齒科學會 2002 大韓小兒齒科學會誌 Vol.29 No.3

단방성 법랑모세포종(Unicystic ameloblastoma)은 임상적, 방사선적 및 병리학적 소견과 치료방법 등이 법랑모세포종과 구별되어 따로 분류된 질환이다. 임상적, 방사선적으로는 치성낭종의 소견을 보이는 단방성 병소이며 조직학적으로 낭종의 소견과 함께 법랑모세포종의 소견을 보인다. 하악 구치부에 호발하며 악골에 무통성 종창을 야기할 수 있으나 대개는 무증상인 경우가 많고 대부분 미맹출치 치관을 둘러싼 방사선 투과성 병소로 나타나며 방사선적으로 함치성낭(dentigerous cyst)이나 잔류낭(residual cyst)과 유사하다. 조직학적으로 낭종상피의 법랑모세포종성 변화(luminal type), 낭종강 내 종양결절의 돌출(intraluminal type), 결합조직 내로 법랑모세포종 세포의 증식(mural type)등의 소견을 보인다. 본 증례는 좌측 안면부 종창을 주소로 내원한 8세 남자 환아에서 임상적, 방사선적 검사 후 낭종의 완전 적출술(enucle-ation)및 장골이식(iliac bone graft)을 시행하였으며 생검을 통해 단방성 법랑모세포종이라 확진되었고 양호한 치료 결과를 얻었기에 이에 보고하는 바이다. The unicystic ameloblastoma deserves separate consideration on the basis if its clinical, radiologic, and patho-logic features and its response to treatment. It refers to those cystic lesions that show clinical, radiographic, or gross features of a jaw cyst, but on histologic examination show a typical ameloblastomatous epithelium lining part of the cyst cavity. The lesion is most commonly found on the mandible posterior area, and often asympto-matic, although large lesions may cause a painless swelling of the jaws. The lesion typically appears as a cir-cumscribed radiolucency that surrounds the crown of an unerupted molar. These are usually considered to be a dentigerous, residual cyst on the relationship of the lesion to teeth in the area. These are usually considered to be a dentigerous, residual cyst on the relationship of the lesion to teeth in the area. Three histopathologic variants of unicystic ameloblastoma may be seen. 1) Luminal type, 2) Intraluminal type, 3) Mural type. In this case, these tumor was treated as cysts by enucleation with iliac bone graft, and the diagnosis of ameloblastoma is made after microscopic examination of the presumed cyst.