사철나무 알칼로이드, Euojaponine의 NMR스펙트럼의 분석

柳載夏,李沼映,李叔淵,韓秉勳 숙명여자대학교 약학연구소 1994 약학논문집-숙명여자대학교 Vol.10 No.-

The strutures of euojaponines, alkaloidal components from Euonymus japonica are composed of β-agarofuran type sesquiterpene and pyridic dibasic acid, and they are linked via cyclodiester bonds. The structures of these compounds were elucidated by the application of various two dimensional NMR methods. From the results of complete interpretation of NMR spectra, several correlating aspects between structure and spectral pattern of sesquiterpene moiety were found, which can be utilized for the structural determination of the same family compounds.

Mycobacterium abscessus에 의한 슬관절 감염1예

류숙원,이창규,허진,신규성,김장수,배숙영,장은아,서인범,김영기,이갑노 대한임상병리학회 2001 대한임상병리학회지 Vol.21 No.5

성교육 프로그램이 청소년 성의식과 성태도에 미치는 효과 : 정신병원 청소년병동 입원환자를 대상으로

류미숙 외 국립서울병원 정신보건교육·연구센터 2008 정신건강정책포럼 Vol.2 No.1

• Purpose : Sexual Education Program on adolescence sexual health has been developed by researchers in accordance with the national education courses. However, there have been not the study which found the effects of this program on sexual consciousness and sexual attitudes of psychiatric in-patient adolescents. • Method : Non-equivalent control group pretest-posttest design was used. Twenty six adolescents participated in an experiment. National Seoul mental hospital in-patients were selected for a convenience sampling method and have been taught the sexual education program during six weeks. • Result : There were significant differences in the sexual consciousness(t:-2.835. p:0.009) and sexual attitudes(t:-1.826. p:0.008) after the sexual education program • Conclusion : Since the sexual education program can affirmative influence on the sexual consciousness and sexual attitudes of the adolescence, it is recommendable to perform the sexual education program suitable for every stage of growth and development.

고학력 여성인력 개발 및 활용을 위한 평생학습 지원체제 연구

박승호,유숙영 서울여자대학교 여성연구소 2006 여성연구논총 Vol.21 No.-

One of the most serious problems of our society is the very low rate of high educated or high skilled women's social participation rate, and limited opportunity in higher value-added businesses for women. Efforts to make human resources of high educated women are so urgent for entering top 10 countries with competitive human power that Korean government enacted laws promoting development and use of them. These steps can be proper only when based on understanding of their real situation and their needs. With study on relative documents and survey on high educated women, we made some suggestions for a lifelong learning support system promoting development and use of high educated woman resources. First, the system should be based on woman's needs driven from their places in their life cycles. Second, the system sould be various on the learning style and characteristics of women. Third, collaborative relations between lifelong learning system and the local community need to be built. Forth, woman lerners should be encouraged by emotional supports from other family members and shared household chores. To develop and use high educated woman resources, more educational facilities in the community should be used for women to learn at any time and in any place. Second, more active supports should be offered through close cooperation among lifelong educational institutes. Woman learners can manage their course of career development with the database on their learning. Third, by database on high educated women, they should be given more opportunities to get appropriated places for their abilities. Forth, higher value-added business for high educated women should be developed. Finally, more opportunities of grant-type lifelong education should be offered to them.

Efficient Unlinkable Secret Handshakes for Anonymous Communications

Eun-Kyung Ryu1,Kee-Young Yoo,Keum-Sook Ha 보안공학연구지원센터(JSE) 2010 보안공학연구논문지 Vol.7 No.6

The technique of secret handshake is used as a fundamental building block for anonymous peer-to-peer communications over untrusted networks. However, the fact that most existing schemes fail to meet unlinkability causes the use of schemes to limit for practical use. In this paper, we provide new constructions for unlinkable secret handshake, allowing arbitrary two communication parties with the same role in either one single group or multiple groups to privately authenticate each other. Compared to previous works, our techniques have much better performance in terms of both computational and communication cost, while they obtain good security results.

대유행 인플루엔자(H1N1 2009) 급성호흡곤란증후군에 대한 체외막 산소화 장치의 조기적용 1예

이경학,이길수,오원섭,유숙원,천성빈,이승준 대한감염학회 2010 감염과 화학요법 Vol.42 No.2

Despite advanced technologies in intensive care, pandemic influenza (H1N1 2009) can rapidly progress to acute respiratory distress syndrome (ARDS) and cause death in a small subset of patients. Extracorporeal membrane oxygenation (ECMO) is expected to provide adequate gas exchange, to reduce ventilator-induced lung injury and, eventually, to improve outcome in these patients. A previously healthy, young female received mechanically ventilatory support because of rapidly progressive respiratory failure caused by 2009 H1N1 influenza. As she failed to respond to high ventilatory support, ECMO was instituted at 6 hours after admission. We describe detailed course of case and literature review on ECMO, helping physicians make a decision to initiate ECMO in patients with influenza-related ARDS.

Park Ryu Sook Gallery : Korea's Art Galleries

Lee Jae-yeon Curator, Park Ryu Sook Gallery The Korea Foundation 2001 Koreana (English) Vol.15 No.4

Isolation of Alkaloids with Immune Stimulating Activity from Oryza sativa cv. Heugnambyeo

Ryu, Min Ju;Chung, Ha Sook 덕성여자대학교 대학원 2011 덕성여자대학교 대학원 논문집 Vol.13 No.-

We describe the immune stimulatory effects of compounds determined by means of activity-monitored extraction and isolation techniques. As a result,4-carboethoxy-6~methoxy-2-quinolone(1) and 4-carboethoxy-6-hydroxy-2-quinolone(2) were isolated from the ethyl acetate-soluble fraction of the Oryza sativa cv. Heugnambyeo bran, and were determined to exert significant inhibitory effects on macrophage cell line (murine RAW 264.7) and murine splenocytes. The structures were elucidated on the basis of spectroscopic evidence, particularly the results obtained via hetero nuclear multiple-bond connectivity and high-resolution MS spectroscopy. Up to date, compound (1) was isolated as natural sources for the first time.

Innocent Characters in th Novels of Dickens

Ryu, Myung Sook 서울대학교 1976 영학논집 Vol.1 No.1

Antibody Induced Capping of Surface Antigens in Trichomonas vaginalis

Ryu,Jae-Sook,Shin,Myeong-Heon,Min,Duk-Young INSTITUTE OF TROPICAL MEDICINE YONSEI UNIVERSITY 1992 YONSEI REPORTS ON TROPICAL MEDICINE Vol.23 No.1

기생충의 숙주에 감염시 여러 가지 방법으로 숙주의 면역반응을 회피(escape)한다고 한다. 이질아메바, 트라파노조마, Naegleria fowleri 등에서는 숙주 면역반응의 회피기전의 일환으로 충체 표면항원(surface antigen)을 외부로 탈락시키거나 재생산(renewal)함이 보고된 바 있다. 이 연구에서는 질트리코모나스에서 표면항원의 capping(antigen redistribution)이 일어나는지 관찰하였다. Log-stage의 살아있는 충제(2×10(6))를 질트리고모나스로 면역시킬 토끼혈청(1:5)과 4℃ 30분간 반응시킨 후 fluorescein conjugated goat anit-rabbit IgG(1:30)와 4℃에서 30분 반응시키고 세척 후 즉시 1% paraformaldehyde로 고정하거나 37℃에서 30분내지 2시간 방치한 후 고정하고 형광현미경으로 관찰하였다. 또한 대사억제제인 sodium azide와 미세소관(microtubule)합성 억제제인 vincristine sulfate와 colcemid를 혈청 및 형광항체에 넣어 capping에 영향을 미치는지 관찰하였다. 충체를 4℃ 또는 25℃에서 30분 내지 2시간 반응시킨 군에서는 20% 정도의 copping의 관찰되는데 비해 TSP-1배지에서 37℃, 2시간 반응시켰을 때 60∼70%가 일어났다. 대개 polar capping이었는데, 일부의 충체는 형광물질을 완전히 벗어버려 충체에는 형광이 없었다. Sodium azide의 여러농도(0,025M-0.5M)에서 capping이 현저히 저하되었다. 그러나, vincristine sulfate와 colcemid(5-0.25 g/ml)는 capping에 별 영향을 미치지 않았다. 이상의 결과로 질트리코모나스는 표면으로부터 항체를 제거하여 숙주의 면역반응에 저항하는 것으로 사료되며 이 반응은 반응온도 및 신진대사에 의존되었다. The capping phenomenon, a parasite's escape mechanism from host's immune response by removal of the antibody bound to antigens on parasite's surface membrane, was observed in Trichomonas vaginalis in vitro. An isolated strain of T. vaginalis (HY-9) was incubated with rabbit anti-serum at 4℃, 25℃ and 37℃ for 30 minutes, 1 hour and 1 hours, and then treated with fluorescein labelled anti-rabbit IgG. The cell-capping process was observed obviously under fluorescein microscope, and was temperature dependent. Sodium azide, a metabolic inhibitor, inhibited the capping of T. vaginalis, whereas colchicine and vicristine, the microtubule synthesis inhibitors, did not affect the capping formation. These results suggest that antibody-induced membrane antigen modulation of T. vaginalis may have a role to host's immune response.