판막 질환에서의 심근 섬유화 : 심근 조직을 이용한 형태학적 연구 및 혈청 생화학적 지표의 분석

강수진,박덕우,송재관,박경민,송종민,강덕현,한기훈,송현,이재원,주석중,송명근,김정선 대한순환기학회 2004 Korean Circulation Journal Vol.34 No.2

Kim,Seong-soo : Possiblity of Low Salting Process in Gae-Woo Jeot(Salted and Fermented Gastrophoda) and Changes in Fatty Acid Composition during Fermntation 低鹽化 可能性 檢討 및 熱成중 脂肪酸 組成의 變化

姜永周,河璡桓,金永東,宋大鎭,金洙賢,金成洙 제주대학교 1990 논문집 Vol.30 No.-

To establish the way of processing of Gae-Woo jeot which used abalone intestine that has not been systematically used compare to its characteristic taste and fame as main ingredient and to develop as a local tourist good, the change of constituents the quality of salted fish products suring Gae-Woo jeot fermentation were examined. The results are as follows. 1. In the organoleptic test, Gae-Woo jeot which fermented through 65 days were dominant and the group of 105 salkt concentration were better than that of 20%. It was the best of 10% salted products to add small abalone. Both law salted(10%) and high salted (20%) Gae-Woo jeot were similar in general constityents, nutrients and texture. 2. Compositions of highly unsaturated acid were farely high to 45.6% and 46.1% in small abalone added froup and top sheel added group respectively. during 3 months fermentation low decreasing rate of 3~4% was shown. EPA(eicosapentaenoic acid) was approximately 7~8% and DHA(docosahexaenoic acid) was extremely low to be less than 0.3%. 3. In the changes General composition and pH, pH was within range of 4~5.5, 9~12% in protein, 3~5% in total sugar, 0.5~1% in lipid and approximately 1% in ash. 4. Gae-Woo jeot can be made with 10% low salting method, and 10% group gets all the better for taste, small abalone adding is recommended. 5. When low salt fermented fish of 10% is processed, it is highly recommended to put sorbitol, ethyl alcohol, lactic acid or other humectant for better taste and longer storage and good quality food additives must be developed for tourist and presently applied mil ordering transportation must be sought.

트레드밀 운동시 흡기근 테이핑이 폐활량에 미치는 영향

김민지,신수영,송월섭,조수진,최동락,황미진,황진규,박진현,김경,Dennis W. Fell 대구대학교 특수교육재활과학연구소 2011 再活科學硏究 Vol.29 No.1

이 연구는 트레드밀 운동과 키네시오 테이핑의 효과에 따른 폐활량의 변화를 알아보기 위해 26명의 비흡연자가 참가하였으며 키네시오 테이핑을 적용하지 않은 그룹과 키네시오 테이핑을 적용한 두 그룹으로 무작위로 배정하고 각 군들을 주 3회 6주간의 트레드밀 훈련을 실시하였다. 실험 전과 후, 스파이로미터를 사용하여 키네시오 테이핑의 적용 따른 폐활량 변화 효과를 측정하였다. 이 연구의 결과를 종합해보면 키네시오 테이핑을 적용 그룹에서 적용하지 않은 그룹에 비해 FVC, FEV1에서 유의한 증가를 보였다. 이러한 결과는 건강한 성인에서 키네시오 테이핑을 적용한 경우 키네시오 테이핑을 적용하지 않고 트레드밀 운동을 한 경우보다 폐활량의 향상에 효과적이라고 생각되어진다. The purpose of this study was to investigate the variation of vital capacity(VC) according to the effects of kinesio taping with treadmill exercise. Twenty-six non-smokers were participated in this research and these subjects were randomly assigned into two groups. To measure the VC variation effects of kinesio taping, spirometer was used. The collected data were analyzed statistically by using a paired Mauchly test and repeated measure ANOVA. The results of this study were as follows; A group: treadmill with kinesio taping B group: treadmill without kinesio taping. Between A and B, there were significant differences. In the case of A group, there was 11.66% increase of VC, during 3 weeks experiment(p<.01). In the case of B group, there were significant differences, 3.35% increase of VC, during 3 weeks taping intervention(p<.01). After 6 weeks experiment, the improvement of VC shown a significant difference with intergroup (p<.05). From this result, it was revealed that treadmill exercise with kinesio taping was effective to improve VC to healthy adult than treadmill exercise without kinesio taping.

新梢頂端培養에 의한 대추나무(Zizyphus jujuba Miller)의 callus로부터 植物體 再分化

宋沅燮,金鎭洙,劉成吾 圓光大學校大學院 1991 論文集 Vol.8 No.-

Organogenesis from callus induced from shoot tip in vitro cultured was examined with using different strength of MS medium containing various concentration of different plant growth regulators alone and its combination in jujube (Zizyphus jujuba Miller). Callus induction was favorable in the treatment of concentration of 2,4-D 1.0, 0.3mg/1 adding on MS medium. Favorable shoot proliferation from callus subcultured on medium for shooting appeared in the treatment of 0.5mg/1 BAP alone adding on 1/2 MS medium. For rooting induction 1/2 MS medium supplemented with the combination of 0.5 or 1.5mg/1 IBA and 0.1, 1.0mg/1 BAP was most effective but 1/2 MS medium containing IBA alone had little effect. Keywords:organogenesis;shoot;callus;jujube MS=Murashige and Skoog Abbreviations:2,4-D=2,4-dichlorophenoxyacetic acid BAP=6-benzylamino purine IBA=indol-3-butylic acid

백서의 복강내에 투여한 Mitomycin-C-Polyglycolic acid 제형이 장기에 미치는 영향에 관한 연구

송규상,강대영,최정목,노승무,정경수,오정연,김진향,양준목,최선웅,이진호,조준식,민병무,김용백,김창식,박근성,김승영,김학용,인현빈 충남대학교 의과대학 지역사회의학연구소 1998 충남의대잡지 Vol.25 No.1

To evaluate the in-vivo effects of mitomycin-C-polyglycolic acid composite(MMC-PGA) the disk: shaped composite were implanted into the peritoneal cavity of the Sprague-Dawley rats. The pathologic changes were examined at various time points up to 12 weeks. Initially the soft tissue around the inserted disks showed capillary congestion at 3 days. Inflammatory infiltrates with foreign body giant cells appeared from the 2nd week and reached peak response at 6-8 weeks. These reaction diminished prominently at 12 weeks. No specific pathologic change was found in the liver, the kidneys, and the heart. The above results suggest that the MMC-PGA composite can serve as a new device for intraperitoneal chemotherapy of various types of cancers.

관엽식물의 잎모양, 크기, 수형에 따른 시각적 인식이 뇌파변화 및 이미지 평가에 미치는 영향

송종은,엄수진,김수연,손기철,이종섭 충북대학교 첨단원예기술개발연구센터 1999 연구보고서 Vol.4 No.-

실내 환경내에서 관엽식물의 보다 효과적인 이용과 시각, 심리환경 스트레스 경감을 목적으로 관엽식물의 형태적 특성이 인간의 정신생리와 심리에 미치는 영향을 알아보고자 잎모양이 다른 아로우카리아(Araucaria excelsa)와 벤자민고무나무(Ficus benjamina), 잎크기가 다른 네프로네피스(Nephrolephis exaltata)와 스킨답서스(Scindapsus aureas), 그리고 수형이 다른 관음죽(Rhapis humilis)과 아레카야자(Chrysalidocarpus lutescens)를 선정하여 각 식물당 남녀 24명 총 72명을 대상으로 뇌파(Computerized EEG)검사, 혈압, 맥박, 시각이미지 평가를 시행하였다. 각 식물에 따른 뇌파를 비교한 결과 뚜렷한 차이를 보이지 않아 관엽식물의 관상에서 잎의 모양, 크기 및 수형이 있는 상태에서 모두 유의한 감소를 보여 스트레스 감소 효과와 안정 효과를 보인 것으로 나타났다. 그러나 각 식물간에는 유의한 차이는 없었다. 이러한 사실은 기존 연구에서 보여준 결과인 식물의 녹색에 대한 정신생리적 반응과 녹(綠)면적에 의한 뇌파변화는 인정되었지만 식물종류에 따른 반응은 중요하게 작용하지 않는 것으로 보여진다. 관엽식물에 대한 이미지는 평가는 4개의 요인 심미성, 청량감, 안정성, 질감성 인자로 구성되었다. 각 인자에 대한 식물종류간에 차이를 조사한 결과 서로 다른 특성을 보였으나 4인자인 질감성 차원에서는 차이가 없었다 이는 의식적으로 인식되는 시각적 이미지 평가요소에서 제 1인자인 심미성과 제 2인자인 청량성이 더 중요하게 작용되는 것으로 판단되었다. 앞으로 보다 명확한 효과를 검정하기 위해 녹시율(綠視率)과 여러 식물 종류를 조합한 좀 더 세밀한 비교와 함께 시간흐름에 따른 뇌파비교를 동시에 조사 분석하는 것이 필요한 것으로 판단된다.

부신 결핵에 의한 Addison씨병 1예

송치운,구본정,안봉수,전준식,안미애,이진홍,송민호,김영건,노흥규 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.2

Addison's disease is a rare primary adrenal insufficient disorder resulting from chronic deficiency of adrenal cortical hormones. Clinical manefestations are generalized weakenss, weight loss, hyperpigmentation (especially sun exposed area and mucous membrane), hypotension, hyponatremia, hyperkalemia, gastrointestinal symptoms (involving anorexia, nausea, vomiting, abdominal pain). A 34-year-old woman has experienced slowly progressive generalized weakenss and skin pigmentation, anorexia, nausea, vomiting with ascites and diffuse abdominal pain. On the time of admission, her main clinical manifestations were anorexia, nausea, vomiting, fatigue, generalized weakness, amenorrhea, hair loss, diffuse abdominal pain revealed as Addison's disease due to bilateral adrenal tuberculosis. Her adrenal insufficient symptoms were recovered with the replacement of adrenocortical hormones and antituberculous medications. After treatment, Her skin pigmentation was decreased and menstruation was reappeared. Here we experienced one cases of Addison's disease with tuberculous peritonitis.

희귀 진세노사이드 Rg6, Rg4, Rk3 및 Rh4의 효능 연구

정규진, 이지현, 조수현, 송규용 충남대학교 약학대학 의약품개발연구소 2017 藥學論文集 Vol.32 No.-

The research on the efficacy of rare ginsenosides in comparison to that of major ginsenosides has not been performed systematìcally and is insufficient, Therefore, with based on the literature survey, the efficacy of the rare ginsenosides, such as Rg6, Rg4, Rk3, and Rh4, is reviewed, and the direction for further research is presented. Sìnce ginsenosides Rg6, Rg4, Rk3, and Rh4 show very diverse and strong activities in various disease models, such as antioxidant activity, anticancer activity, immunity enhancing activity, antì-microbial activity, etc., it can be strong potential candidates as new materials derived from natural materials for pharmaceuticals, cosmetics. and food industry. However, most research is limited to the in-vitro efficacy. Therefore, to systematically investigate the in-vivo effìcacy of individual ginsenosides is required for the application of the ingredients. To do that, it is essential to establish standardized mass production and iso-lation method for individual rare ginsenosides

반복적인 실신 및 실신전환자의 기립경사 검사시 뇌혈류 변화

조수진,김준수,이광호,정진상,송희정,이상철,서정돈,이원로 대한신경과학회 1999 대한신경과학회지 Vol.17 No.3

급성 SO_2중독이 임신흰쥐 및 태자간에 미치는 영향에 관한 조직화학적 연구

송인문,유진화,한갑수 慶熙大學校 1989 論文集 Vol.18 No.-

The purpose of present study was to clarify the effect of sulfur dioxide exposure on enzymatic activities of the liver in pregnant and fetal rats by histochemical method. Female pregnant rats (Sprague-Dawley strain) were used in this study. The animals were exposed to 50ppm SO_2 in gas. chamber for 5 minutes, 15 minutes, 30 minutes and 60 minutes and were sacrificed on 17 days, 19 days and full term of gestation period and fetal liver were taken. The changes of enzymatic activities of cytochrome oxidase, acid phosphatase, alkaline phosphatase and lactate dehydrogenase were observed by histochemical stainings. Significant data have been summarized as follows; 1. In the pregnant rat, 19th fetal rat and full term fetal rat, the enzymatic activities of cytochrome oxidase and lactate dehydrogenase of SO_2 exposure group decreased in comparison with the control group. 2. In the pregnant rat, 19th fetal rat and full term fetal rat, the enzymatic activities of acid phosphatase of SO_2 exposure group increased in comparison with the control group. But alkaline phosphatase has showed a no significant changes in comparison with the control group. 3. In the 17th fetal rat, the changes of enzymatic activities of cytochrome oxidase and lactate dehydrogenase of SO_2 exposed liver showed a mild positive activity as it was in the control group. However, acid phosphatase activities has showed a negative activity in the both group. 4. The enzymatic activities of cytochrome oxidase, acid phosphatase, alkaline phosphatase and lactate dehydrogenase of SO_2 exposed liver showed a significant changes in the pregnant rat in comparison with the fetal rat.