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RISS 인기검색어
- 검색키워드
- 저자 : ( Shogo Nakamura ) (검색결과 4 건)
- 무료
- 기관 내 무료
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Naoki Nakamura,Osamu Takahashi,Minobu Kamo,Shogo Hatanaka,Haruna Endo,Norifumi Mizuno,Naoto Shikama,Mami Ogita,Kenji Sekiguchi 한국유방암학회 2014 Journal of breast cancer Vol.17 No.2
Purpose: The purpose of this study was to quantify the targetcoverage, homogeneity, and robustness of the dose distributionsagainst geometrical uncertainties associated with fourwhole breast radiotherapy techniques. Methods: The study wasbased on the planning-computed tomography-datasets of 20patients who underwent whole breast radiotherapy. A total offour treatment plans (wedge, field-in-field [FIF], hybrid intensitymodulatedradiotherapy [IMRT], and full IMRT) were created foreach patient. The hybrid IMRT plans comprised two opposedtangential open beams plus two IMRT beams. Setup errors weresimulated by moving the beam isocenters by 5 mm in the anterioror posterior direction. Results: With the original plan, thewedge technique yielded a high volume receiving ≥107% of theprescription dose (V107; 7.5%±4.2%), whereas the other threetechniques yielded excellent target coverage and homogeneity. A 5 mm anterior displacement caused a large and significant increasein the V107 (+5.2%±4.1%, p<0.01) with the FIF plan, butnot with the hybrid IMRT (+0.4%±1.2%, p=0.11) or full IMRT(+0.7%±1.8%, p=0.10) plan. A 5-mm posterior displacementcaused a large decrease in the V95 with the hybrid IMRT (-2.5%±3.7%, p<0.01) and full IMRT (-4.3%±5.1%, p<0.01) plans, butnot with the FIF plan (+0.1%±0.7%, p=0.74). The decrease inV95 was significantly smaller with the hybrid IMRT plan than withthe full IMRT plan (p<0.01). Conclusion: The FIF, hybrid IMRT,and full IMRT plans offered excellent target coverage and homogeneity. Hybrid IMRT provided better robustness against geometricaluncertainties than full IMRT, whereas FIF provided comparablerobustness to that of hybrid IMRT
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Hydrographic Model Test on Prevention against Vortex Occurrence for Vertical Bulb Turbine
Yamato, Shoichi,Nakamura, Shogo,Furukawa, Akinori Korean Society for Fluid machinery 2009 International journal of fluid machinery and syste Vol.2 No.4
A vertical bulb turbine unit with elbow type draft tube has been developed due to avoidance of complicated assembling and long standstill period at overhaul in comparison with conventional horizontal bulb turbine unit. Before designing the prototype vertical bulb unit, a hydrographic model test was carried out to establish the ideal design concept for this innovative generating unit. Froude similarity is not available for vortex occurrence. Consequently, an intake structure without air entraining vortices under all the flow conditions is developed, and it is confirmed that the surge wave at load rejection is not affected harmful influence for other constructions.
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( Sakatoku akihiro ),( Daisuke Tanaka ),( Shogo Nakamura ) 한국미생물 · 생명공학회 2013 Journal of microbiology and biotechnology Vol.23 No.6
In a previous study, we isolated and reported a second species of the Saccharophagus genus, Saccharophagus sp. strain Myt-1. In the present study, an alginate lyase gene (algMytC) from the genomic DNA of Myt-1 was cloned and characterized. The DNA sequence fragment obtained contained an open reading frame of 1,032 bp that encoded a protein of 343 amino acids with an estimated molecular mass of 37.6 kDa and a pI of 6.60. The deduced protein, AlgMytC, had the conserved amino acid sequences (RTELREM, QIH, YFKAGVYNQ) of the polysaccharide lyase family 7. A BLAST homology search indicated that AlgMytC shared an amino acid sequence identity of 95.9% with alg7A of S. degradans 2-40. The cloned and purified AlgMytC protein showed optimal activity at 40oC, and retained more than 90% of its total activity even after treatment at 25oC for 24 h. AlgMytC was very alkaliphilic with an optimal pH of 9.0, and more than 90% of its activity was retained in the pH range 8.5-10.0. Moreover, AlgMytC was stable over a wide pH range. The activity of AlgMytC was also stable in the presence of various detergents.
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Norifumi Fujii,Manabu Tsukamoto,Nobukazu Okimoto,Miyuki Mori,Yoshiaki Ikejiri,Toru Yoshioka,Makoto Kawasaki,Nobuhiro Kito,Junya Ozawa,Ryoichi Nakamura,Shogo Takano,Saeko Fujiwara 대한골다공증학회 2021 Osteoporosis and Sarcopenia Vol.7 No.2
Objectives: The relationship between weight-related load and bone mineral density (BMD)/bone microstructure under normal load conditions using high-resolution peripheral quantitative computed tomography (HR-pQCT) remains unconfirmed. The study aims to investigate the differences in effect of body mass index (BMI) on BMD/bone microstructure of loaded and unloaded bones, respectively, in Japanese postmenopausal women. Methods: Fifty-seven postmenopausal women underwent HR-pQCT on the tibia and radius. Correlation analysis, principal component (PC) analysis, and hierarchical multiple regression were performed to examine the relationship between BMI and HR-pQCT parameters. Results: Several microstructural parameters of the tibia and radius correlated with BMI through a simple correlation analysis, and these relationships remained unchanged even with an age-adjusted partial correlation analysis. PC analysis was conducted using seven bone microstructure parameters. The first PC (PC1) reflected all parameters of trabecular and cortical bone microstructures, except for cortical porosity, whereas the second PC (PC2) reflected only cortical bone microstructure. Hierarchical multiple regression analysis indicated that BMI was more strongly related to BMD/bone microstructure in the tibia than in the radius. Furthermore, BMI was associated with trabecular/cortical BMD, and PC1 (not PC2) of the tibia and radius. Thus, BMI was strongly related to the trabecular bone microstructure rather than the cortical bone microstructure. Conclusions: Our data confirmed that BMI is associated with volumetric BMD and trabecular bone microstructure parameters in the tibia and radius. However, although BMI may be more related to HRpQCT parameters in the tibia than in the radius, the magnitude of association is modest.
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