대중문화 콘텐츠 변화에 따른 한중 신조어 비교 연구

맹상삼(Xiang-Shan Meng),이광호(Kwang-Ho Lee) 한국엔터테인먼트산업학회 2020 한국엔터테인먼트산업학회논문지 Vol.14 No.6

본 논문은 대중문화 콘텐츠 변화에 의한 신조어를 비교 연구한 것이다. 한국과 중국은 교류가 긴밀해지면서 언어까지 영향을 주고받는다. 이에 따라 신조한 국어와 동일한 언어 특성을 가진 신조중국어가 발견된다. 또한 신조어는 언어의 새로운 발전 결과물이라고 여긴다. 이러한 신조어는 한국과 중국의 젊은층에서 널리 사용하고 있는 상황이다. 따라서 언어가 소통을 전제로 한다는 측면에서 학문적인 연구를 통하여 한중 신조어를 명확히 인식하는 것이 바람직하다. 2018년 신조중국어의 특성을 중심으로 먼저 2017년 이전의 신조중국어와 합성, 약어, 대치 등의 형태적인 요소와 비유, 은어 등 의미적인 측면에 의해 비교하여 분석하였다. 이를 통해 2018년 신조중국어의 특성을 추출하였다. 다음에 이러한 신조어의 구성방법에 의해 2018년의 신조한국어와의 공통점과 차이점도 확인하였다. 그리고 한국어와 중국어 신조어를 분석한 결과, 기존의 언어 재활용 현상이 두드러짐도 확인하였다. 이러한 한중 신조어가 표준어로 정착하는 과정을 보기 위해 신조어의 구성방법을 정확하게 탐색해보고자 하는 것이 중요하다. The purpose of this study is to analyze new words in Korean and Chinese based on changes in popular culture. As China and Korea embrace increasingly close communication in recent years, their languages have influenced each other. A lot of new Korean and Chinese words have been discovered to have the same linguistic characteristics. New words are considered as new developments of a language. They are welcomed and widely used by young people in Korea and China. Therefore, in terms of the communicative function of languages, it is worthwhile to understand new words in Korean and Chinese from the perspective of academic research. This study takes Chinese words created in 2018 as the research object. Firstly, a morphological and semantic comparison of Chinese words created in 2018 and those created in 2017 is carried out to extract the characteristic indicators of Chinese words created in 2018, with emphasis on compound words, abbreviations, substitutions, patters and rhetorical expressions. Secondly, the similarities and differences of these Chinese words with Korean words created in 2018 in terms of morphology are analyzed. Finally, after conducting sample classification and comparison, the characteristics of new Chinese and Korean words and the interaction mechanism under mutual influence are concluded. According to the study, the majority of the new words are created on the basis of existing words. Thus, it is important to explore the morphology of new words as a standard language.

사회문화적 양상에 따른 한중 [+사람] 신어의 비교 연구 - 2010년대의‘ㅇㅇ족(族)’계열 신어의 구조적과 의미 양상을 중심으로 -

맹상삼(Xiang-Shan Meng) 한국엔터테인먼트산업학회 2021 한국엔터테인먼트산업학회논문지 Vol.15 No.7

본 연구는 한·중 [+사람] 신어를 조어하는 데에 공통으로 사용된‘ㅇㅇ족(族)’계열 신어를 대상으로하여 2010부터 2019년까지 10년간의 출현 양상을 살펴보고,‘ㅇㅇ족(族)’계열 신어의 구조적과 의미 양상인 공통점 및 차이점을 밝히는 것에 목적을 둔다. 출현 양상에 있어서‘ㅇㅇ족’의 한국 신어는 10년간에 꾸준히 생성되었고,‘ㅇㅇ族’의 중국 신어는 2017년에 형성되지 않았다가 2018년과 2019년에 적은 양으로 다시 나타났다. ‘ㅇㅇ족(族)’계열 신어는 구조적 특징에 차이점이 보인다. 가장 활발히 형성된 합성의 경우 한국‘ㅇㅇ족’신어의 선행요소는 다양한 어원의 요소와 결합유형을 보여 주었다. 그러나‘ㅇㅇ族’으로 생성된 중국 신어는 고유어 합성만이 활발하여 제한된 조어양상을 보여 주었다. 파생도 이러한 차이점을 나타냈다. 한·중‘ㅇㅇ족(族)’계열 신어의 의미 자질로 분류하고 특성을 살펴봄으로써 그들은 보여주는 특성이 다르지만, 모두 다양한 영역의 문화와 현상, 그리고 새로운 표현 의미들을 선행요소로 수용한 것으로 나왔다. 이러한 다양함이 신어 생성에서 작용하여 영향을 끼친 것으로 보인다. The purpose of this study is to examine the appearance patterns of the ‘ㅇㅇjok(family)’ line, which is commonly used to abbreviate Korean and Chinese Neologisms, from 2010 to 2019, and to identify the structural and Meaningful similarities and differences of the ‘ㅇㅇjok(family)’ line Neologisms. In terms of appearance, the Korean Neologisms of the ‘ㅇㅇjok’ was constantly created for 10 years, and the Chinese Neologisms of the ‘ㅇㅇfamily’ was not formed in 2017 but reappeared in small quantities in 2018 and 2019. Korean and Chinese Neologisms of the ‘ㅇㅇjok(family)’ show differences in their structural characteristics. In the case of the most actively formed compound, the preceding elements of the Korean ‘ㅇㅇjok’ Neologisms showed various etymological elements and types. However, the Chinese Neologisms produced by ‘ㅇㅇfamily’ showed a limited linguistic aspect due to the active compound of native languages. Derivative also showed these differences. By Classifying ‘ㅇㅇjok(family)’ line in Korean and Chinese Neologisms as meaningful qualities, they have different characteristics, but both of them were found to have accepted colorful culture and phenomenon in various areas, and new expression meanings as their precedence element. These diverse cultures appear to have influenced the creation of the new language.

《春香传》在五十年代中国的译介与传播

金长善(Jin, Chang-Shan), 王萌(Wang, Meng) 조선대학교 국제문화연구원 2012 국제문화연구 Vol.5 No.2

한반도 고전문학의 대표작 <춘향전>은 세계 속에 널리 알려진 지명도가 높은 작품의 하나이다. <춘향전>은 작품 그 자체의 독특한 특성과 1950년대 중국과 북한 간의 독특한 사회 역사적 환경으로 인하여 소설, 희곡 등 장르로 번역 개편 되여 광범위하게 수용 전파되면서 독특한 양상을 보여주었다. 1950년대 중국에서의 창극 <춘향전>과 소설 <춘향전>의 번역 전파는 당시 중국과 북한의 국민들간의 친선적 문화 공감대를 형성하는데 일조하였을 뿐만 아니라 중한 문학교류사의 중요한 한 페이지를 장식하였다.

Sensitivity of Plasmodium falciparum to Antimalarial Drugs in Hainan Island, China

Shan-Qing Wang,Guang-Ze Wang,Yu-Chun Li,Feng Meng,Shi-Gan Lin,Zhen-Hu Zhu,Ding-Wei Sun,Chang-Hua He,Xi-Min Hu,Jian-Wei Du 대한기생충학열대의학회 2015 The Korean Journal of Parasitology Vol.53 No.1

Hypolipidemic and Antioxidant Effects of Malus toringoides (Rehd.) Hughes Leaves in High-Fat-Diet-Induced Hyperlipidemic Rats

Shan Huang,Haifeng Liu,Ning Meng,Bin Li,Jule Wang 한국식품영양과학회 2017 Journal of medicinal food Vol.20 No.3

Malus toringoides (Rehd.) Hughes (MT) leaves are traditionally used as a medicine for treating or preventing cardiovascular disease in Tibet. In addition to the effect of this medicinal plant on thrombosis, we tested its effect on dyslipidemia in a hypolipidemic rat model. A total of 60 healthy Sprague-Dawley rats were randomly divided into six groups, as follows: normal control, model control, simvastatin groups, and MT low-, medium-, and high-dose groups. The normal controls were fed with a normal diet, whereas all other groups were fed with a high-fat diet. After 6 weeks, the high-fat diet had induced hyperlipidemia in the rats, which were then orally administered with different doses of MT leaf extract (50, 100, and 200 mg/kg) for an additional 6 weeks. Serum levels of total cholesterol (TC), triglycerides (TG), low- and high-density lipoprotein cholesterol (LDL-c and HDL-c, respectively), as well as the antioxidant capacity of glutathione peroxidase (GSHP-x), superoxide dismutase (SOD), and malondialdehyde (MDA) were measured at the end of the study. MT significantly reduced serum TC, TG, and LDL-c and increased the HDL-c content in MT-treated rats compared with the model group. These changes were dose dependent. MT treatment also significantly elevated the activity of SOD and GSHP-x, and decreased the serum levels of MDA compared with untreated hyperlipidemic rats, thereby increasing serum antioxidant capacity. In addition, MT reduced liver steatosis in hyperlipidemic rats. Overall, MT exerts considerable hypolipidemic and antioxidant properties.

Contributed Mini Review : New paradigms on siRNA local application

( Meng Pan ),( Jin Wen Ni ),( Hui Ming He ),( Shan Gao ),( Xiao Hong Duan ) 생화학분자생물학회(구 한국생화학분자생물학회) 2015 BMB Reports Vol.48 No.3

Small interfering RNA (siRNA) functions through pairing with specific mRNA sequences and results in the mRNA`s degradation. It is a potential therapeutic approach for many diseases caused by altered gene expression. The delivery of siRNA is still a major problem due to its rapid degradation in the circulation. Various strategies have been proposed to help with the cellular uptake of siRNA and short or small hairpin RNA (shRNA). Here, we reviewed recently published data regarding local applications of siRNA. Compared with systemic delivery methods, local delivery of siRNA/shRNA has many advantages, such as targeting the specific tissues or organs, mimicking a gene knockout effect, or developing certain diseases models. The eye, brain, and tumor tissues are ‘hot’ target tissues/ organs for local siRNA delivery. The siRNA can be delivered locally, in naked form, with chemical modifications, or in formulations with viral or non-viral vectors, such as liposomes and nanoparticles. This review provides a comprehensive overview of RNAi local administration and potential future applications in clinical treatment. [BMB Reports 2015; 48(3): 147-152]

Anti-Inflammatory Activity of Epimedium brevicornu Maxim Ethanol Extract

Shan Huang,Ning Meng,Bingquan Chang,Xianghua Quan,RuiYing Yuan,Bin Li 한국식품영양과학회 2018 Journal of medicinal food Vol.21 No.7

Epimedium brevicornu Maxim has been used as a traditional herbal drug in China. In this study, the anti-inflammatory effects of E. brevicornu Maxim ethanol extract (EBME) were investigated in RAW264.7 macrophages and mice challenged with lipopolysaccharide (LPS). Results showed that EBME attenuated inflammation by decreasing the production of several proinflammatory mediators, such as nitric oxide (NO), prostaglandin (PG) E2, inducible nitric oxide synthase, and cyclooxygenase-2, in LPS-stimulated RAW264.7 macrophages. EBME increased the expression of heme oxygenase-1 (HO-1) and promoted the nuclear translocation of nuclear factor erythroid 2-related factor 2. The inhibitory effects of EBME on LPS-stimulated NO and PGE2 expression were partially reversed by HO-1 inhibitor. EBME also elicited an anti-inflammatory effect by inhibiting the production of tumor necrosis factor-α, interleukin (IL)-1β, and IL-6 in LPS-induced peritonitis. Therefore, EBME exhibited anti-inflammatory effects in vitro and in vivo.

Increased retinoic acid signaling decreases lung metastasis in salivary adenoid cystic carcinoma by inhibiting the noncanonical Notch1 pathway

Zhou Meng-jiao,Yang Jia-jie,Ma Ting-yao,Feng Ge-xuan,Wang Xue-lian,Wang Li-Yong,Ge Yu-ze,Gao Ran,Hong-liang Liu,Shan Lin,Kong Lu,Chen Xiao-hong 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

MYB-NFIB fusion and NOTCH1 mutation are common hallmark genetic events in salivary gland adenoid cystic carcinoma (SACC). However, abnormal expression of MYB and NOTCH1 is also observed in patients without MYB-NFIB fusion and NOTCH1 mutation. Here, we explore in-depth the molecular mechanisms of lung metastasis through single-cell RNA sequencing (scRNA-seq) and exome target capture sequencing in two SACC patients without MYB-NFIB fusion and NOTCH1 mutation. Twenty-five types of cells in primary and metastatic tissues were identified via Seurat clustering and categorized into four main stages ranging from near-normal to cancer-based on the abundance of each cell cluster in normal tissue. In this context, we identified the Notch signaling pathway enrichment in almost all cancer cells; RNA velocity, trajectory, and sub-clustering analyses were performed to deeply investigate cancer progenitor-like cell clusters in primary tumor-associated lung metastases, and signature genes of progenitor-like cells were enriched in the “MYC_TARGETS_V2” gene set. In vitro, we detected the NICD1-MYB-MYC complex by co-immunoprecipitation (Co-IP) and incidentally identified retinoic acid (RA) as an endogenous antagonist of genes in the “MYC_TARGETS_V2” gene set. Following this, we confirmed that all-trans retinoic acid (ATRA) suppresses the lung metastasis of SACC by correcting erroneous cell differentiation mainly caused by aberrant NOTCH1 or MYB expression. Bioinformatic, RNA-seq, and immunohistochemical (IHC) analyses of primary tissues and metastatic lung tissues from patients with SACC suggested that RA system insufficiency partially promotes lung metastasis. These findings imply the value of the RA system in diagnosis and treatment.

Research on the Expert System of Mathematics Application Question Teaching

Feng Shan,Meng Pan,Wang Yaling 보안공학연구지원센터 2016 International Journal of Multimedia and Ubiquitous Vol.11 No.12

In view of the automatic solution process of the elementary school mathematics application question, this article has carried on the research to the mathematics application question teaching expert system. Firstly, this paper introduces the definition and structure of the expert system. Then the system structure and function module of the mathematics application question teaching expert system design, gives a detailed description and design of information extraction module, application of rule base, application type library and application question solving process. In this paper, the application of the problem is divided into an integer one step calculation problem, the integer two steps to calculate the application and fractional scores of three parts of the application. At the same time, according to different types of applications, the structural characteristics of the analysis. According to the information extraction model and mathematical operation rules, the overall framework and function modules of the design mathematics teaching expert system are designed. And the realization process is studied. The research results show that the system can be used to demonstrate the solution of mathematical problems in detail. Help students to understand the application of the problem solving process. Make it better learn to know how to solve the problem. And it is helpful for teachers to easily understand method and carry on the teaching process. This also means that the system has practical application value. As a bridge between mathematical theory and practice, mathematical application problems have become more and more important in the implementation of mathematical quality education. It is necessary to cultivate students' mathematics application consciousness and optimize the students' thinking quality. After leaving school, every student can still think about problems and solve the problem mathematically. In consequence, pay more attention to the teaching of application problems, make the cultivation of the consciousness of "use" of mathematics throughout the whole high school stage, and integrate training students' ability of solving mathematics application question into daily teaching, which is conductive to promote the development of students' mathematical innovation, stimulate mathematics learning interest, and improve internal drive of mathematics learning. In our country, many middle school mathematics teachers have carried on the thorough research on the mathematics application problems teaching, which also has made some progress. However, there are still a lot of mistakes in the application teaching in the daily used system. In particular, the college entrance examination still has its influences, teaching material adjustment is not in place, how to teach the application problems plays a crucial role in the overall implementation of the quality education reform.

Inhibition of the interaction between Hippo/YAP and Akt signaling with ursolic acid and 3′3-diindolylmethane suppresses esophageal cancer tumorigenesis

Ruo Yu Meng,Cong Shan Li,Dan Hu,Soon-Gu Kwon,Hua Jin,Ok Hee Chai,Ju-Seog Lee,김수미 대한약리학회 2023 The Korean Journal of Physiology & Pharmacology Vol.27 No.5

Hippo/YAP signaling hinders cancer progression. Inactivation of this pathway contributes to the development of esophageal cancer by activation of Akt. However, the possible interaction between Akt and Hippo/YAP pathways in esophageal cancer progression is unclear. In this study, we found that ursolic acid (UA) plus 3′3-diindolylmethane (DIM) efficiently suppressed the oncogenic Akt/Gsk-3β signaling pathway while activating the Hippo tumor suppressor pathway in esophageal cancer cells. Moreover, the addition of the Akt inhibitor LY294002 and the PI3K inhibitor 3-methyladenine enhanced the inhibitory effects of UA plus DIM on Akt pathway activation and further stimulated the Hippo pathway, including the suppression of YAP nuclear translocation in esophageal cancer cells. Silencing YAP under UA plus DIM conditions significantly increased the activation of the tumor suppressor PTEN in esophageal cancer cells, while decreasing p-Akt activation, indicating that the Akt signaling pathway could be down-regulated in esophageal cancer cells by targeting PTEN. Furthermore, in a xenograft nude mice model, UA plus DIM treatment effectively diminished esophageal tumors by inactivating the Akt pathway and stimulating the Hippo signaling pathway. Thus, our study highlights a feedback loop between the PI3K/Akt and Hippo signaling pathways in esophageal cancer cells, implying that a low dose of UA plus DIM could serve as a promising chemotherapeutic combination strategy in the treatment of esophageal cancer.