위선암의 Billroth Ⅰ 수술시 수기문합과 자동문합의 비교

노승무,나호청,윤완희,장일성,배진선 충남대학교 의과대학 지역사회의학연구소 1995 충남의대잡지 Vol.22 No.1

The aim of this study was to establish wheather the EEA stapler method was a secure and simple procedure for gastroduodenostomy in the stomach cancer, without increased morbidity and mortality rates compared with the manual method. During the period September 1990 to August 1993, a stapler method (n=86) or manual method n=38) was performed in 124 patients. The results were as follows ; 1) Distal one third of the stomach was prevalent site of tumor(73.4%). On gastric antrum located tumor, manual and stapler method was performed on the 32 cases(84.2%) and 59 cases(68.6%), respectively. On gastric body located tumor, manual and stapler method was performed on 6 cases(15.8%) and 27 cases(31.4%), respectively. 2) The radical and palliative resection rate of manual method was 35 cases(92.1%) and 3 cases(7.9%). The radical and palliative resection rate of stapler method was 81 cases(94.2%) and 5 cases(5.8%). 3) Major complications of the anastomotic site were stenosis and bleeding. Two cases of stenosis were observed in the stapled group(2.3%), and no case in the manual group. One case of bleeding had occured in the stapled group(1.2%), and no case in the manual group. 4) The average operation time of manual and stapler method was 269 minutes and 265 minutes, respectively. 5) The average hospital stay of manual and stapler method was 18.5 day and 19.0 day, respectively.

액정유체의 압력 유도 흐름에서의 분자 배향과 속도 분포

한원희,조정호,전종기,노상균,고승태 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

본 연구에서는 액정의 압력 유도 흐름에 대해 적응성 토크 균형식과 코시 운동량보존식을 액정 연속체 이론의 핵심이 되는 Leslie-Ericksen 이론에 적용하여 수치해석 방법들로 풀어내었다.비선형 편미분 방정식계의 해를 구할 때 경계조건으로 쓰인 분자 배향닻 조건은 평행 닻조건(parallel anchoring)과 직교 닻조건(homeotropic anchoring)이다.분자 배향 분포는 평행 닻조건에서나 직교 닻조건에서나 시간이 지남에 따라 간단한 전단 흐름에서와 같이 3차원 비평판 배향의 구조를 갖게되지만 배향 비틀림의 구조가 다름을 알 수 있었다.배향 비틀링의 3차원적 구조를 갖게됨에 따라 압력 구배가 걸리는 흐름방향의 주 속도 분포뿐만 아니라 직교되는 방향으로 부 속도분포가 생기며 정상상태로 발전해가는 속도 분포 진화는 점근적이 아닌 진동적이다.비정상상태에서나 정상상태에서 속도 분포는 비 뉴톤성임을 알 수 있다.비등방성 Miesowicz 점도 순열에 따른 평행 닻조건에서의 더 많은 흐름량을 볼수 있고 직교 닻조건에서는 벽면에서 보이는 작은 속도 구배량의 특징을 가진다.

C₄유분을 이용한 옥텐류의 합성에 있어서 1,3-Butadiene의 함량에 따른 이량화 촉매의 수명에 관한 연구

전종기,한원희,조정호,고승태,노상균 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

Selective hydrogenation of 1,3-butadiene in C4 raffinate was carried out in fixed bed reactor using Pd/a1unina catalysts, Concentration of 1,3-butadiene in C4 raffinate could be reduced under 100 ppm.The life of dimerization catalyst using C4 raffinate after selective hydrogenation was longer than that of dimerization catalyst without selective hydrogenation.It was found that dilution of olefin concentration in feed was effective to increase dimerization catalyst life.

AAL2 다중 사용자 그룹을 위한 Dynamic-Adaptive MLT 스케줄링 알고리즘

김태준,홍석원,노희승 明知大學校 産業技術硏究所 1999 産業技術硏究所論文集 Vol.18 No.-

The ATM Adaptation Layer 2(AAL2) was made to allow multiplexing of multiple user voice packets in a single ATM connection. In delivering voice packets over AAL2, delay and jitter are the major challenges for rendering good audio quality. in this paper, we assume two separate user groups, one of which requests the higher service quality than the other. in order to provide low delay jitter boundary for the high priority user packets, we propose a modified Minimum Laxity Threshold (MLT) scheduling algorithm, called D-AMLT in this paper, and show the simulation results using this algorithm. We also compare the results with the ones using other algorithms.

'PRO/II with PROVISION' 범용성 화학공정 모사기를 이용한 원유정제공정의 모사에 관한 연구

조정호,전종기,한원희,고승태,노상균 동양대학교 2001 동양대학교 논문집 Vol.7 No.1

Crude refinery unit is the first step in refining crude oil.Crude refinery unit is divided into the following two parts.The first par is atmospheric crude distillation column and crude preheating train.Because of the massive furnace duty to heat crude oil for distillation most units have an elaborate preheat train, in which the crude oil is preheated by back exchange with hot pumparound liquids from the unit.The other part is composed of the vacuum distillation unit.In this study, a step-by-step procedure for simulating an atmospheric crude distillation column by using PRO/II with PROVISION as a general purpose chemical process simulator is introduced.

대학생의 취업스트레스와 자아존중감, 자아효능감, 외모관리행동의 관계

김보라,김유진,김지희,노혜진,오승희,홍지혜,황윤희,박선아 水原大學校 2016 論文集 Vol.30 No.-

Purpose: Many university students are under a lot of job-seeking stress because the employment rate is low. This study sought to determine the relationship between job-seeking stress, self esteem, self efficacy and appearance management behavior amongst university students focusing on nursing. Methods: This descriptive correlational study evaluated the relationships between job-seeking stress, self esteem, self efficacy and appearance management behavior of 340 university students was conducted between September 1 and October 5, 2015. Results: The correlational analysis between job-seeking stress, self esteem, self efficacy and appearance management behavior revealed a negative correlation between job-seeking stress, self esteem and self efficacy and a positive correlation between job-seeking stress and appearance management behavior. In addition, age also correlated with self esteem, self efficacy and appearance management behavior. Conclusion: Stress correlated with self esteem and self efficacy and appearance management behavior. Therefore job-seeking stress may be reduced through not only self esteem and self efficacy enhancement programs but also management according to age.

항암화학요법 치료시 환자에서 발생하는 오심 및 구토에서의 정맥주사용 및 경구용 Tropisetron의 제 4상 연구

배진선,김장용,장일성,윤완희,노승무,홍기훈 최신의학사 1997 最新醫學 Vol.40 No.7

위암세포에 의한 종양침윤 림프구의 면역반응 억제기전에 관한 연구

박정규,송규상,서광선,최정목,배진선,장일성,윤완희,노승무,조은경,백태현 大韓免疫學會 1995 大韓免疫學會誌 Vol.17 No.3

Tumor-infiltrating lymphocytes ('1°ILs) interact most closely with tumor cells and thus are more likely to reflect tumor host interactions accurately. But it is unknown whether such T cells are nonspecific inflammatory cells or a subset of specific host immune responses. In this study, there was no clear correlation between the infiltration of T lymphocytes in stomach cancer and the overexpression of c-ErbB-2 or increasing class I MHC expression on tumor cells. A positive correlation was seen between the presence of TILs in the tumor and tumors with diploidy by flow cytometric DNA analysis. The proliferative responses of Ills stimulated with IL-2, anti-CD3 mAb, or both were examined. When compared to normal mucosal-associated lymphoid tissue lymphocytes, the proliferative response of TILs to high dose IL-2 was minimal. A similarly poor response to anti-CD3 mAb plus IL-2 was also observed. The freshly isolated TILs exhibit reduced ability to proliferate in response to IL-2, anti-CD3 mAb or both. The microenvironment of the tumor suppresses the proliferative capacity of the TILs. The mechanism of this suppression remains unknown. It could be mediated by suppressor cells, by soluble substances within the tumor, or both. To examine this question, supernatants of stomach cancer cells (SNSNU-1) were tested for the presence of immunosuppressive factors. Human peripheral blood T-cells and tumor-draining lymph node lymphocytes (TDLNL) were incubated for 3 days with SNSNU-1 and then assessed for proliferative responses to PMA, anti-CD28 mAb, or both and for the inducibility to express IFN- r or IL-4 mRNA to PMA. Peripheral blood T-cells pretreated with SNSNU-1 were unable to proliferate in response to PMA, anti-CD28 mAb or both. SNSNU-1 also produces inhibitory activities of TDLNL proliferative response to PMA or anti-CD28 mAb and PMA (49%, 52%, respectively). In contrast, culture supernatants obtained from HEp-2, K562 or Daudi showed normal proliferative responsiveness of peripheral blood T-cells and TDLNL by PMA, anti-CD28 mAb or both.

Efficacy of Serum Antithrombin III Rest in Patients With Severe Traumatic Brain Injury

Hee Seung Noh,Sun Geon Yoon,Kyunghak Choi,Kyu-Hyouck Kyung,Min Soo Kim 대한신경손상학회 2023 Korean Journal of Neurotrauma Vol.19 No.2

Immune reactions following traumatic brain injury (TBI) cause many complications, including intravascular dissemination. Antithrombin III (AT-III) plays an important role in suppressing abnormal clot formation and ensuring hemostasis. Therefore, we investigated the efficacy of serum AT-III in patients with severe TBI.

Nanog signaling in cancer promotes stem-like phenotype and immune evasion.

Noh, Kyung Hee,Kim, Bo Wook,Song, Kwon-Ho,Cho, Hanbyoul,Lee, Young-Ho,Kim, Jin Hee,Chung, Joon-Yong,Kim, Jae-Hoon,Hewitt, Stephen M,Seong, Seung-Yong,Mao, Chih-Ping,Wu, T-C,Kim, Tae Woo American Society for Clinical Investigation 2012 The Journal of clinical investigation Vol.122 No.11

<P>Adaptation of tumor cells to the host is a major cause of cancer progression, failure of therapy, and ultimately death. Immune selection drives this adaptation in human cancer by enriching tumor cells with a cancer stem cell-like (CSC-like) phenotype that makes them resistant to CTL-mediated apoptosis; however, the mechanisms that mediate CSC maintenance and proliferation are largely unknown. Here, we report that CTL-mediated immune selection drives the evolution of tumor cells toward a CSC-like phenotype and that the CSC-like phenotype arises through the Akt signaling pathway via transcriptional induction of Tcl1a by Nanog. Furthermore, we found that hyperactivation of the Nanog/Tcl1a/Akt signaling axis was conserved across multiple types of human cancer. Inhibition of Nanog in a murine model of colon cancer rendered tumor cells susceptible to immune-mediated clearance and led to successful, long-term control of the disease. Our findings establish a firm link among immune selection, disease progression, and the development of a stem-like tumor phenotype in human cancer and implicate the Nanog/Tcl1a/Akt pathway as a central molecular target in this process.</P>