http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
The oncoprotein, gankyrin, is up-regulated in middle ear cholesteatoma
Kim, Ki Hyun,Lim, Hye Jin,Kim, Yeon Ju,Kim, Seung Won,Kim, Young Sun,Tian, Chunjie,Park, Keehyun,Park, Tae Jun,Choung, Yun-Hoon Scandinavian University Press 2014 Acta oto-laryngologica Vol.134 No.3
<P><I>Conclusion:</I> Gankyrin seems to be a better biomarker for cholesteatoma compared with Ki-67. <I>Objective:</I> Gankyrin is an oncoprotein, and occurs in cancers but not in benign diseases. The goal of this study was to compare expression of gankyrin, p53, and a proliferation marker (Ki-67) in cholesteatoma and retroauricular skin (RAS), and to evaluate their significance as clinical parameters. <I>Methods:</I> The levels of expression of gankyrin, Ki-67, and p53 in 10 cholesteatoma and 10 paired samples of normal RAS were evaluated by immunohistochemical staining and Western blot. The results were compared with clinical profiles to investigate a correlation. <I>Results:</I> The expression of gankyrin, Ki-67, and p53 proteins was observed in both basal and suprabasal layers of cholesteatoma. The intensity of gankyrin expression was ‘positive’ in two cases (20%) and ‘strongly positive’ in eight cases (80%); p53 expression in the suprabasal layer was ‘positive’ in 70% of cases; and the Ki-67 staining was ‘focal’ in 80% of cases. In RAS, these proteins were expressed dominantly in the basal layer. Western blot analysis showed that the gankyrin band was more intense in cholesteatoma than in RAS for three of four cases (<I>p</I> < 0.05). However, there was no significant difference in the expression of gankyrin, Ki-67, and p53 according to clinical variables.</P>
한의진단명과 진단요건의 표준화 연구 II (표준화 실례) : 2차년도 연구결과 중간 보고
양기상,최선미,최승훈,안규석,박경모,박종현,김성우,신승호,정우열,전병훈,고현,김정범,신상우,김성훈,김동희,권영규,엄현섭,장혜옥 한국한의학연구원 1996 한국한의학연구원논문집 Vol.2 No.1
The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the second year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows; - differential diagnosis according to condition of body fluid, differentiation of syndromes according to the state of qi and blood, differential diagnosis according to relative excessiveness or deficiency of yin and yang(氣血陰陽津液辨證) - differentiation of diseases according to pathological changes of the viscera and their interrelation - analyzing and differentiating of febrile diseases in accordance with the theory of the six channels(傷寒辨證) The individual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name(異名), notion of diagnosis pattern, index of differentiation of symptoms and signs(辨證指標), the main point of diagnosis, analysis of diagnosis pattern(證候分析), discrimination of diagnosis pattern(證候鑑別), a way of curing a diseases(治法), prescription(處方), herb in common use(常用藥物), diseases appearing the diagnosis pattern(常見疾病), documents(文獻調査). This study was carried out on the basis of the Chinese documents and references.
partial pulpotomy를 이용한 미성숙 영구치의 치수 치료: 증례 보고
장기택,노승철,한세현,김정욱,김용수 大韓小兒齒科學會 1999 大韓小兒齒科學會誌 Vol.26 No.4
치수치료의 주요한 목적은 구강조직의 본래의 건강을 유지하는 것이며, 치수치료 시 가장 중요하고 어려운 점은 치수조직의 건강상태 또는 염증의 정도를 결정함으로써 최선의 치료방법을 결정하는 것이다. 미성숙 영구치는 풍부한 혈류 공급으로 다양한 손상에 성공적으로 반응하게끔 치수의 능력을 향상시킴으로써 많은 치수치료 술식을 위한 좋은 조건을 가지고 있다. 기저재(base) 또는 이장재(liner), 간접 치수복조술, 직접 치수복조술, 그리고 치경부 치수절단술을 포함한 여러 종류의 보존적인 치수치료가 미성숙 영구치를 위해 추천되어 왔다. 근래에는 외상으로 인하여 치수노출된 영구절치를 치료하는데 있어 주로 제시된 부분 치수절단술(partial pulpotomy)이 우식으로 인해 치수노출된 영구대구치를 치료하는 또다른 술식으로 제안되고 있다. 부분 치수절단술 후 치아가 다음의 criteria를 만족시킬 때 치유가 되었다고 결론지었다. 1. 임상적 무증상 2. dentin bridge 형성의 방사선학적 증거 3. 방사선상에 치수내 또는 치근단 병소가 없다는 증거 4. 지속적인 치근 발육과 미성숙 치아의 치근첨 형성 5. 성숙된 치아에서 정상적인 상아질의 축적 6. 전기치수검사에서 양성 반응 이에 저자는 미성숙 영구치에서 우식 또는 외상으로 인한 치수노출시 부분 치수절단술을 행하여 양호한 결과를 얻었기에 이를 보고하는 바이다. The primary objective of pulp treatment is to maintain the integrity and health of the oral tissues. The most important and difficult aspect of pulp therapy is determining the health of the pulp, or its stage of inflammation, so that a decision can be made regarding the best form of treatment. Immature permanent teeth are good candidates for many pulp healing procedures, due to their rich blood supply, which is believed to enhance the pulp's ability to react successfully to various insults. Healing was considered to have taken place when the tooth fulfilled the following criteria: 1. Abscence of clinical symtoms 2. Radiographic evidence of dentin bridge formation 3. No intrapulpal or periapical pathosis was evident radiographically 4. Continued root development and closure of the apex in immature teeth 5. Normal dentin apposition in mature teeth 6. Positive response to electrical pulp test This presents a report of cases in which immature permanent teeth, pulp-exposed by caries or trauma, was treated successfully by partial pulpotomy
천추 전방에서 발생한 신경절 세포종 : 증례 보고 A Case Report
강현구,이승로,박동우,박충기,함창곡,박용욱 한양대학교 의과대학 2002 한양의대 학술지 Vol.22 No.2
We have experienced a case of presacral ganglioneuroma. So, we report a peripheral ganglioneuroma of sacral origin. The patient is 34-year-old man with intermittent low back pain and right sciatica. Myelographic computed tomography revealed extradural lobulated low attenuated tumor lesion within spinal canal at the level of L5 and S1. Tumor indented the thecal sac to the left side, and extended into the pelvic cavity through the intervertebral foramen between S1 and S2. The mass was surgically excised and turned out to be ganglioneuroma pathologically.
그루지아 민가의 전통 발효유에서 분리한 유산균의 이화학적 특성
신승이,최기춘,김종현,박정수,이영환 全南大學校 農業科學技術硏究所 1999 農業科學技術硏究 Vol.34 No.-
그루지아의 전통 발효유로부터 유산 생성과 항균성이 우수한 3주의 균주를 최종 분리, 선발하고 각각 Lactobacillus bulgaricus (L bulga G82), Lactobacillus acidophilus (L. acid G86), 그리고, Streptococcus thermophilus (S. thermo G90)로 동정하였다. 이들 유산균을 starter로 요구르트를 제조하여 이화학적 특성을 조사한 결과, pH는 4.0∼4.5의 범위를 보였으며, pH 4.0으로 L. acid G86 균주가 가장 낮게 나타났다. 또한 0.1N HCl에 대한 완충능은 4.50∼5.12ml, 0.1N NaOHdp 대한 완충능은 3.74∼4.98ml의 범위를 보였고, 3 균주 중 L acid G86 균주가 산-염기에 대하여 가장 높은 완충능을 나타내었다. 산도는 0.95∼1.16%, 점도는 1,984∼2,232 cps 그리고 생균수는 1.4x109∼3.0x109으로 조사 되었다. in vitro에서의 콜레스테롤 저하 정도는 L. acid G86 균주가 약 35%로 가장 높은 저하 정도를 보였고, L. bulga G82와 S. thermo G90 균주는 각각 약 32%, 24%이었다. Three strains of inhibitory lactic acid bacteria against pathogenic microorganism were isolated from traditional fermented milk of Georgia, and than, identified to be Lactobacillus bulgaricus (L bulga G82), Lactobacillus acidophilus (L acid G86) and Streptococcus thermophilus (S. thermo G90), respectively. These strains were used to starter for yogurts. So, we made yogurts, and evaluated their phyco-chemical properties. The range of pH value was 4.0∼4.5, and L. acid G86 strain was the lower pH value for 4,0. The buffer capacity against 0.1N HCI and 0.1N NaOH were 4,50~5.12ml and 3.74~4.98ml. The acidity, viscosity and viable cell counts of yogurt were 0.95∼1/16%, 1.984∼2,232 cps and 1.4x109∼3.0x109, respectively. Among the three strains, L. acid G86 strain was have the best ability of lowering cholesterol level in vitro, the value were about 35%. The L. bulga G82 and S. thermo G90 were around 32% and 24%, respectively.