Creutzfeldt-Jacob병 1례

홍승철,한진희,정종현,김소양,허균,이성필 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.1

저자들은 Creutzfeldt-Jacob병 1례를 경험하였기에 문헌고찰과 함께 보고하는 바이다. 환자는 약 4개월에 걸친 비교적 짧은 기간 동안 중증의 인지 기능 장애와 시각 장애, 보행장애와 하지의 약화, 불수의적 운동 등과 함께 섬망상태에까지 이르게 되어 본원 정신과에 입원하게 되었다. 정신상태 검사상, 반응시간의 지체, 언어장애와 보속증, 시간에 대한 지남력 장애, 주의 집중력 장애, 단기 및 장기 기억 장애, 추상적 사고능력 장애 등의 소견을 보였고, 이러한 증상들은 입원후 치료에도 불구하고 빠르게 악화되었다. 뇌파검사상 지속적인 다발초점성 서파가 모든 전극에서, 특히 우측 전두부에서 현저하게 나타나는 소견을 보였고, 병리조직학적 검사상 대뇌 피질에 신경손실을 동반한 해면화와 신경교 증식증을 나타냈다. 이상의 소견들은 모두 CJD의 진단에 합당하였다. We report a case of Creutzfeldt-Jacob disease and review the relevant literatures. This 56-year-old male patient was admitted to our hospital with a history of rapidly progressing cognitive dysfunction, visual disturbance, gait disturbance, weakness, involuntary movement of lower extremities, and the symptoms of delirium. On mental status examination, he showed psychomotor retardation, speech disturbance, perseveration, disorientation, impairment of short-term and long-term memory, and inability of abstract thinking. He had a rapid downhill course, along with shakiness of trunk, rigidity of the limbs, myoclonus, confusion, and finally, inability to speak or move on the bedside. On electroencephalogram(EEG), continuous multifocal show delta activities were found in all leads, especially in the right frontal areas. Brain biopsy showed, spongiosis with neuronal loss and gliosis noted at the cerebral cortex. These findings were compatible with Creutzfeldt-Jacob disease.

한강변 응급센터에 내원한 익수환자에 대한 임상적 고찰

양진홍,박규남,최승필,김영민,김세경 대한응급의학회 2001 대한응급의학회지 Vol.12 No.2

Background: There are approximately 2,400 drowning deaths reported every year in Korea, but there are few good reports about submerged patients visiting the emergency room, so this study was designed to investigate the clinical characteristics and outcomes of submerged patients treated at an emergency medical center near the Han river. Methods: A retrospective review of 123 cases of submerged patients admitted to our emergency medical center over a 5 year period from 1996 to 2000 was conducted. Results: Among the 123 submerged patients, there were 66 males and 57 females, and their mean age was 33.18. The common cause of submersions was a suicide attempt, followed by lack of attention, unknown etiology, and water sports such as swimming. Most of the patients were transported to ER by 119 ambulance. In-hospital CPR was performed on 27(22%) cases. At initial ECG rhythm of these cases, asystole was noted if 25 patients; VF and pulseless electrical activity, respectively, were noted in two others. Prehospital CPR had been performed on all in-hospital CPR cases except 2. Prolonged ROSC after succesful CPR was noted in 13 cases, The mean duration of CPR was 26 minutes. Five patients survived after CPR. Their neurologic outcomes were assessed on CPC(cerebral performance category). Three patients were categorized in CPC1, the other two patients were categorized in CPC3 and CPC4. Conclusion: Submerged patient's visits to emergency medical center near the Han river were most frequent in summer for suicide purposes. Drowned patients were more hypothermic than other cardiac arrest cases, and resulted in better outcome even with prolonged arrest time, if they were given appropriate prehospital CPR and aggreissive in-hospital resuscitation.

소뇌 출혈을 동반한 침입성 부비동 아스페르길루스증 1예

양현덕,박성욱,손일홍,이지용,석승한,조광호,이성수 圓光大學校 醫科學硏究所 2003 圓光醫科學 Vol.18 No.2

자궁 경부 도말표본에서 Chlamydia trachomatis의 양성율에 대한 연구

홍기언,김의한,김민관,양승하,강상균 순천향의학연구소 1995 Journal of Soonchunhyang Medical Science Vol.1 No.1

The uterine cervicitis by chlamydia trachomatis(CT) shows no specific clinical symptoms except mucopurulent leukorrhea, but it causes severe complications such as endometritis, salpingitis, abortion and infertility. Fortunately, the treatment of cervicitis by CT is simple and effective, so that this infection is once diagnosed and then confirmed, the treatment is not difficult. To study the positive rate of CT infection, we collected 65 patients inflicted with mucopurulent leukorrhea in Chonan city. Specimen was collected by swab and for the detection of CT, ELISA was carried out. The positive cases are observed in 15 out of 65 patients (positive rate is 23.1%). This positive rate was rather lower than other reports, however, this results were higher we expected With this result, the clinicians keep in mind the fact that the causes of uterine cervicitis by CT occupy the large proportions as gonorrhea.

휠체어댄스스포츠의 현황과 활성화 방안

홍양자,강승애 이화여자대학교 동작과학연구소 2004 이화체육논집 Vol.8 No.-

Wheelchair dance sports started by ballroom dancing associated with dancers who were not disabled. Holland is generally credited as being the birth place of wheelchair dance sport, c Evert Castelein in the 1970s and furthered by Corrie van Mugten during the 1980s when she danced the Rumba with Ruud Vermeij during an International Dance Championship in the Royal Albert Hall, London, England. Wheelchair Dance Sports was the latest sport to become an "IPC Sport" in 1988. Today, more than 5,000 dancers(4,000 wheelchair users and 1,5000 non-disabled partners) perform Wheelchair Dance on both a recreational or competitive level in more than 40 countries. Wheelchair dance sports was introduced to Korea by Nobuko Yotsumoto who was a chairman of Japan Wheelchair Dance Sports Federation in 1996. And KWDSF(Korea Wheelchair dance Sports Federation) was started 28, July, 2002. Wheelchair dance sports may be a recreational activity, as an integral part of a rehabilitation program, or be done competitively as a sport. The content of this study demonstrated that an effort which made steady progress toward disabled person's wellbeing should be needed.

여성 요실금에서 Kontinence™와 Compact Elite™의 치료효과 비교

양상국,정상원,오미희,노용수,김홍섭,우응제,박승훈,이수열 건국대학교 의과학연구소 1999 건국의과학학술지 Vol.9 No.-

Biofeedback and pelvic floor electrical stimulation are new modalities that have been advocated for the treatment of female urinary incontinence. The aim of this study was to compare prospectively the therapeutic effect of Kontinence™(HMT Co., Korea) with Compact Elite™(ECL Co., France) in female urinary incontinence. All patients were evaluated with a complete history, physical examination, urinalysis, urine culture and urodynamic study. Eighteen patients were treated with Compact Elite™, and thirteen patients with Kontinence™. Enrolled patients had completed 8 office sessions consisting of biofeedback and intravaginal electrical stimulation according to the program of each machines. Overall treatment response was graded by patients on a scale of complete cure to aggravation. At two weeks after last session, overall improvement rate was 78% in Compact Elite™group and 92% in Kontinence™group(p>0.05). Overall patients' acceptability during treatment course was greater than 80% in both machines(p>0.05). There were no unexpected clinical findings during Kontinence™ treatment. After Kontinence™treatment, there were no laboratory changes including electrocardiography, complete blood count, liver function profile, and chest PA. These results showed that the biofeedback and electrical stimulation with Kontinence™was safe and moderately effective for female urinary incontinence comparable to Compact Elite™. However, long-term results of a larger patients are needed to ensure the therapeutic effect of Kontinence™.

언어행위의 형식적 특성을 밝히기 위한 기초연구

양병환,민형원,홍성기,정승아 漢陽大學校 精神健康硏究 1998 精神健康硏究 Vol.17 No.-

수도권 지역의 의료기기 관련 업체의 실태 조사 연구

양태홍,이우철,김정래,박승환 서울보건대학 1997 서울보건대학 부설 병원경영연구소 논문집 Vol.3 No.1

Recently, the domestic business of medical equipment have many difficult things in the development and sale of new product. To overcome them, it is needed to solidify the co-work system of industry-education marriage. This paper is undertakened to serve an aid in the field of medical equipment. The analysis of data is attempted through the survey by questionaires, and an object of study is the medical business corporation at Seoul area. As a result to review the data it was identifided that this study is able to be applied to the basis material to reconstruct a right role and phase to medical business Also, it`s expected that we're able to use its results as the educational materials to bring up the more qualified students fit to the industrial need.

전자빔을 이용한 공기중 VOC 분해반응 특성

원양수,한도흥,박완식,Tatiana Stuchinskaya,이홍승 영남대학교 환경문제연구소 2000 環境硏究 Vol.20 No.1

공기중 휘발성유기화합물의 처리를 위해 전자빔 가속기를 이용하여 Trichloroethylene(TCE)의 분해특성에 대해 연구하였다. TCE를 포함한 공기는 서로 다른 반응분위기, 초기농도의 변화, 수증기 존재유무와 같은 변수하에서 분해실험이 행해졌다. 산소를 반응분위기가스로 사용하였을 경우 최대분해율이 나타났는데, TCE 초기농도 2000 ppm에 대해 20kGy에서 99%의 분해율을 보였다. TCE 농도는 산소와 공기 조건하에서 지수함수적으로 감소했으며, TCE 분해효율에 대한 수증기 효과가 행해졌다. 수증기 (5600ppm) 존재하에서 TCE분해율은 수증기가 존재하지 않을 경우보다 약 10% 높게 나타났다. 1차 생성물로 Dichloroacetic acid, Dichloroacethyl chloride, Dichloroacethyl ester acetic acid 등이 생성되었고 분해와 산화반응을 통해 CO, CO2로 전환되었다. 또한 Perchloroethylene, Hexachloroethane, Chlorofona Carbon tetrachloride와 같은 과염소탄소 화합물이 생성되었다. Decomposition of trichloroethylene (TCE) in electron beam irradiation was examined in order to get information on treatment of VOC/air. Air containing vaporized TCE has been studied in a flow reactor with different reaction environments, various initial TCE concentration and in presence and absence of water vapor. Maximum decomposition was observed in oxygen reaction environment and degree of decomposition was about 99 % at 20 kGy for 2000 ppm initial TCE. The concentration of TCE exponentially decreased with dose in oxygen and air. The effect of water vapor on TCE decomposition efficiency was examined. The decomposition of TCE in presence of water vapor (5600 ppm) was by ca. 10% higher than in absence of water vapor. Dichloroacetic acid, dichloroacethyl chloride and dichloroethyl ester acetic acid which were identified as primary products, were decomposed and oxidized to give CO and CO2. Perchloroethylene, hexachloroethane, chloroform and carbon tetrachloride were also observed as highly chlorinated products.

말초성 신경아세포종 : 두개골 발생 증례 보고 Involving Skull

박양화,권익승,류연석,신미경,최문배,홍승관,문명선 대한신경외과학회 1988 Journal of Korean neurosurgical society Vol.17 No.4

The peripheral neuroblastomas are malignant neoplasms that originate from the adrenal gland and sympathetic nervous tissues. They usually occur in childhood. They exhibit such malignant features that they metastasize early to lung, liver, bone, rarely skull and other structures. The patients with peripheral neuroblastoma have short duration of symptom and short survival period. They reveal the characteristic light microscopic features that resemble other small cell carcinomas. The establishment of final diagnosis of peripheral neuroblastoma needs various special stainings for small cell carcinomas, and the electron microscopic findings are the most reliable. The authers recently experienced a case of peripheral neuroblastoma in a 26-year old man which involved right frontoparietal skull vault. The only chief complaint was a local non-tender mass at right frontoparietal scalp. Neither headache nor any neurological deficits was detected. Simple skull X-ary revealed a punched out rediolucency at right frontoparietal bone and brain CT showed a superficial elliptical high density mass that enhanced strongly. The mass was totally removed by wide craniectomy. The tumor invaded and penetrated the dura but the arachnoid membrane. at the tumor bed was not invaded by the tumor. The tumor was confirmed as peripheral neuroblastoma by various special stainings for small cell carcinomas. Following surgical resection of the mass, post-operative radiotherpy was offered(4800 rads for about 5 weeks). The patient aggrevated progressively and showed numerous metastases to such bones as lumbar vertebrae, pelvis and humerus to became paraplegic. 8 months after the operation, the patient died.