전통주 주박의 항혈전 활성 평가

김미선(Mi-Sun Kim),이예슬(Ye-Seul Lee),김종식(Jong Sik Kim),신우창(Woo-Chang Shin),손호용(Ho-Yong Sohn) 한국생명과학회 2014 생명과학회지 Vol.24 No.8

전통주 주박을 이용한 고부가가치 식품소재 개발을 위해, 상업적 시설에서 생산된 3종 약주(J-B, J-S, J-Y) 및 2종 탁주(J-H, J-W) 주박의 ethanol 추출물 및 열수 추출물을 조제하고 이들의 혈액응고 저해활성, 혈소판 응집저해 활성 및 인간 적혈구 용혈활성을 평가하였다. 5종 주박의 pH는 3.90~4.29로 유사하였으나, brix는 5.0~27.0으로 다양하게 나타났으며, 수분 및 알코올 함량에서도 시료에 따라 1.8배의 차이를 나타내었다. 주박의 색차와 성분은 첨가된 부재료 및 사용누룩에 좌우되었으며, J-W 주박의 경우 수분함량이 80.3%, brix 13, 알코올 함량 1.8%를 함유하여 다른 주박에 비해 다양한 식품제조에 용이하게 이용 가능하리라 판단되었다. Ethanol 추출효율은 J-H, J-W, J-B, J-S, J-Y의 순, 열수 추출효율은 J-S, J-B, J-W, J-H, J-Y의 순으로 높았으며, 총폴리페놀 및 총플라보노이드함량은 ethanol 추출물 중에서는 J-H, 열수 추출물 중에서는 J-Y 주박에서 가장 높았다. 5종 주박의 10종 추출물은 모두 5 mg/ml 농도까지 인간 적혈구에 대한 용혈활성이 나타나지 않았으며, J-B, J-S, J-Y의 약주 주박의 ethanol 추출물에서 유의적인 혈액응고저해 활성이 나타났으며, J-W 탁주 주박의 열수 추출물에서 thrombin 저해 활성과 J-B, J-S 및 J-H 주박 열수 추출물에서 혈액 응고인자 저해활성을 확인하였다. 혈소판 응집저해 활성평가의 경우 J-W 탁주 주박의 ethanol 및 열수 추출물에서만 아스피린에 필적하는 우수한 활성이 확인되었다. 본 연구결과는 다양한 약주 및 탁주 주박이 항혈전 활성을 가지고 있으며, 주박으로부터 항혈전제 개발이 가능함을 제시하고 있다. In this study, ethanol and hot water extracts of lees from Korean traditional wine (J-B, J-S, J-Y, J-H, and J-W) were prepared, and their effects on blood coagulation, platelet aggregation, and hemolysis of human red blood cells (hRBCs) were investigated to develop functional food ingredients from lees. The pH and brix of the lees ranged from 3.90 to 4.29 and 5.0 to 27.0o, respectively, and there was a huge difference in the water and ethanol content among the lees. The nuruk and additives used affected the color and physicochemical properties of lees. The J-W takju made from only rice and traditional nuruk, which has 13o brix and 1.8% of alcohol, has potential as functional food ingredient. With regard to the extraction yields of lees, higher yields were obtained from J-H, which contains different medicinal plants, in ethanol, followed by J-W, J-B, J-S, and J-Y. Higher extraction yields of lees were obtained from J-S in hot water, followed by J-B, J-W, J-H, and J-Y, respectively. The ethanol extract of J-H and the hot water extract of J-Y had the highest contents of total polyphenol and total flavonoids among the lees extracts. The 10 lees extracts did not show hemolysis activity against hRBCs up to 5 mg/ml. In an anticoagulation activity assay, the ethanol extracts of three yakju lees (J-B, J-S, and J-Y) and the hot water extract of J-W inhibited thrombin activity, whereas the hot water extract of J-B, J-S, and J-H inhibited blood coagulation factors. In an antiplatelet aggregation activity assay, only the J-W takju lees showed significant inhibition activity. Our results suggest that lees from traditional wine had high potential as a novel antithrombosis agent.

Possibility of Empowerment in The Surrendered by Chang-rae Lee

Seul Ki Lee Ewha Institute of English and American Studies 2022 Journal of English and American studies Vol.20 No.1

This paper supports the interpretation that the main characters in Chang-rae Lee’s The Surrendered find liberation in being surrendered. As a novel written by a recognized Korean-American writer about The Korean War, The Surrendered received many reviews concentrating on the author’s writing style and artistry. These early critics stated that the novel’s varying temporal and geographical shifts and the fact that the novel revolves around three different characters make the novel unnecessarily complex. In addition, the scholarly works that do analyze the novel concentrate on the trauma, disability, and post-traumatic stress disorder resulting from the violence. Although prior research touched upon the characters and the symbolism within the setting, I would like to do a more in depth analysis. I use the concept of “abjection” to analyze the symbolism of the three main characters: June, Hector, and Sylvia. All three characters have distinct individuals while also representing others who have survived the social situations they faced. Therefore, it is meaningful to analyze three characters and how they use their status as abjects to find a form of liberation and empowerment.

코로나19 발생에 따른 서울시 골목상권 유형별 회복탄력성 및 생존특성 분석

이슬 ( Lee¸ Seul ),김태건 ( Kim¸ Taegeon ),이수진 ( Lee¸ Sujin ),김갑성 ( Kim¸ Kabsung ) 한국부동산분석학회 2021 부동산분석학회 학술발표논문집 Vol.2021 No.1

본 연구에서는 우리마을가게 상권분석서비스 자료를 활용하여 서울시 골목상권을 대상으로 상권 유형을 구분하고, 코로나19 발생에 따른 상권별 회복탄력성과 생존 특성을 분석하였다. 우선 수요자 특성을 기준으로 골목상권의 유형을 분류하고, 유형별 회복탄력성을 측정하여 그 차이를 파악하였다. 마지막으로 생존분석을 실시하여 골목상권 유형별 생존율의 차이를 확인하고 그에 따른 영향요인을 분석하였다. 골목 상권은 총 4개 유형으로 분류되었으며, 회복탄력성 유동인구와 직장인구의 영향이 큰 유형 1과 젊은 세대 수요층의 영향이 큰 유형 2 상권에서 매출 피해가 크게 나타났으며, 생존분석 결과에서도 유형 2 상권이 가장 취약한 것으로 도출되었다. 골목상권 매출 위기에 영향을 주는 요인으로는 유형 2 상권 여부, 아파트 가격과 면적당 생활인구, 프랜차이즈 점포 비율은 위험을 높이는 요인으로, 면적당 상주인구와 업종 다양성은 위기 발생 위험을 낮추는 것으로 분석되었다. 본 연구는 생활밀접형 상권인 골목상권을 대상으로 상권 유형을 구분하고, 유형별로 회복탄력성과 생존특성을 분석하여 지역 경제 활성화 정책을 위한 기초연구를 제공하였다는 점에서 의의가 있다. 하지만 코로나19 장기화에 따른 추가 데이터 확보와 상권 유형별 세부 업종 등에 대한 차이를 반영한 후속 연구가 요구된다. In this study, we classified Seoul’s Side Street Trade Areas in detail and diagnosed resilience and survival characteristics of each type during the COVID-19. First, using cluster analysis, the Side Street Trade Areas are classified based on the demand to reflect the impact of COVID-19. Next, we measured the resilience of each type of the Side Street Trade Areas and identified differences between types. Finally, in the survival analysis, we plotted Kaplan-Meier curves of each type, and constructed a Cox proportional hazard model. As a result, the Side Street Trade Areas were divided into 4 types. The result of resilience analysis and survival analysis, Type 1 and 2 were vulnerable compared to Type 3 and 4. Type 2 value, Apartment prices, Living population per area, and Franchise store ratio increased risk, while Resident population per area and Industry diversity decreased the risk of crisis. This results are expected to be developing the local economic policies and supporting the Side Street Trade Areas.

학교폭력의 피해에 대한 교사의 법적 책임

이슬밭 이화여자대학교 법학전문대학원 2012 Ewha Law Review Vol.2 No.2

최근 학교폭력으로 인한 자살사건이 사회적으로 큰 파장을 일으켰다. 특히 교사의 책임은 그동안 주로 윤리적 측면에서 논의되어 왔으나 법적 측면에서의 논의는 부족하였다. 이에 본고에서는 교사의 법적 책임에 대하여 민⋅형사책임을 검토하고, 학교폭력과 관련된 현행 제도의 문제점과 새로운 방안에 대하여 검토해 보고자 한다. 교사는 학생에 대한 보호⋅감독의무를 부담하며 이 의무를 위반할 경우, 민사상 불법행위 책임 또는 대리감독자책임을 지게 되며, 판례는 교사의 보호⋅감독의무를 교육관계법령의 취지로부터 도출되는 의무로 파악하고 있다. 한편 교사의 형사책임에 대하여, 형사상 직무유기죄의 책임을 물어야 한다는 주장이 경찰로부터 제기되었다. 그러나 형법해석의 일반원리인 죄형법정주의에 비추어 볼 때 학교폭력사건에서 교사를 형법상 직무유기죄로 처벌하는 것은 어려울 것이다. 한편, 현행 법제하에서 교사가 학교폭력사건에 직면한 경우, 취할 수 있는 조치는 교육적 계도 수준에 그치는 것이 사실이다. 학교폭력예방 및 대책에 관한 법률(이하 ‘학교폭력예방법’이라고 한다)에서는 학교장 또는 학교폭력대책자치위원회를 통한 피해학생의 보호 및 가해학생에 대한 제재 조치를 규정하고 있다. 그러나 가해학생에게 위와 같은 조치를 강제할 수 있는 방법이 미비하여 그 실효성은 크지 않다. 특히 학생의 생활과 가장 가까운 지위에 있는 교사가 어떤 조치를 취할 수 있는지에 대한 규정은 찾을 수 없다. 따라서 교사가 학생에 대한 보호⋅감독의무의무를 성실히 이행하고 학교폭력 발생 시 신속⋅적절한 대처를 할 수 있도록 교사에게 일정한 권한을 부여하는 입법적 논의가 필요하다. Recently, suicide cases related to school violence has aroused special social concern. The responsibility of educators have been under moral debate however legal debate over this issue has been considered to be insufficient. This article is aimed to overlook the legal civil and criminal liabilities of educators and assess the current existing system of school violence into seeking a new measure of policy. In case of violating the legal obligation of supervising an incompetent person, educators have the liability of the civil act article 750(torts) or article 755 (2) (Liability of substitute supervisor). The Supreme Court of Korea explains the terms of legal obligation of supervising an incompetent person of educators, derived from the intentions of the laws and regulations pertaining education. There was an assertion brought up by the police that educators must have the liability of article 122(Abandonment of Duties) in the Criminal Act. In the matter of viewing the Principle of Legality which is one of the fundamentals of interpreting the Criminal Statutes, it seems impossible to penalize educators related to school violence cases in terms of the Criminal Act article 122(Abandonment of Duties). In the Law of School Violation Prevention and Measures, the protection of student victims and management of inflicting students, are regulated by the school principal or the Self-Administration Committee. However, due to the inertia of enforcement measures to inflicting students, it lacks practicality. There is no provision regulating the measures made by educators who are mostly intact to the daily lives of students. Hence, there is a necessity to discuss legislatively to give educators appropriate authority to fulfill the duty of protection and supervision of students and take action in making quick and proper measures.

대한민국 자동차 번호판에서 블록 이진화 기법을 이용한 문자 인식 기법

장인태, 이슬기, 우효정, 안재형 충북대학교 컴퓨터정보통신연구소 2012 컴퓨터정보통신연구 Vol.20 No.1

In this paper, the image binarization method using standard specifications of the vehicle license plate to recognize characters on the plates is proposed. The global binarization method that had a threshold over entire image pixels cannot acuratelly binarize in case that local average brightness are varied to each plates characters regions. The proposed method uses the characters regions in the standard specifications of the korean vehicle license plates as binarization blocks. For installed cameras on national roads and parking areas, the computer simulation results showed average characters recognition rate about 5% higher than the otzu global binarization method.

표정인식을 위한 PCA와 템플릿 정합을 사용한 얼굴 요소 추출

우효정, 이슬기, 김동우, 류성필, 안재형 충북대학교 산업과학기술연구소 2013 산업과학기술연구 논문집 Vol.27 No.2

This paper proposed an extracting algorithm of human facial components for the recognition of facial expressions. First face image is acquired using the Haar-like feature mask from an input image. The face image is divided into two images. One is the upper image including eye and eyebrow. The other is the lower image including mouth and jaw. The extraction of facial components, such as eye and mouth, begins getting eye image and mouth image. Then eigenfaces are produced by the PCA training process with learning images. An eigeneye and an eigenmouth are produced from eigenfaces. Result eye image is obtained by template matching the upper image with the eigeneye, and the mouth image is obtained by template matching the lower image with the eigenmouth. The simulation results show that the proposed method has superior extraction ratio than previous method.

초등학교 고학년 학생의 장애아동에 대한 인식 조사

김보람,김호영,손유라,오진주,윤슬기,이효정,장문영 대한감각통합치료학회 2011 대한감각통합치료학회지 Vol.9 No.1

목적 : 초등학교 고학년 학생의 장애아동에 대한 인식을 알아보는 것이다. 연구방법 : 연구 대상은 김해시에 소재한 통합교육을 실시하지 않는 초등학교의 4, 5, 6학년의 비장애 아동이었다. 연구 기간은 2008년 10월 2일부터 10월 17일까지였으며, 설문지를 사용하였다. 설문지의 하위 영역은 사귐, 활 동, 학업 영역의 세 부분으로 각 10문항으로 이루어져 있으며 SPSS 12.0을 사용하여 분석하였다. 결과 : 장애아동에 대한 인식조사 결과 첫째, 성별에 따른 인식은 남학생보다 여학생의 평균 점수가 높았으나 통계 적으로 유의미한 차이는 없었다. 둘째, 학년에 따른 인식은 4학년의 평균 점수가 가장 높았고 6학년이 가장 낮았으 며 통계적으로 유의미한 차이가 있었다(F=3.546, p<0.05). 셋째, 장애인 접촉 유무에 따른 인식은 접촉 경험이 없 는 학생이 있는 학생보다 평균점수가 높았으나 통계적으로 유의미한 차이는 없었다. 결론 : 비장애학생의 장애아동에 대한 인식은 학년에 따라 차이가 있었다. 본 연구는 작업치료사들에게 장애아동에 대한 또래집단의 인식에 대한 정보를 제공함으로써 학교환경에 대한 이해를 도울 수 있을 것이다. Objective : The purpose of this study was to investigate attitude of grade-schoolers toward children with disabilities. Methods : The subjects of this study were grade-schoolers who have not received an inclusive education in Gim-hae. The study was surveyed from October second to 17th in 2008. The survey was categorized into three parts; comradeship, activity, and study. Each part of the survey consists of 10 questions. Data were analyzed by SPSS (version 12.0). Results : The results were as follows; First, the attitude of girls toward disabled students was non-significant compared to boys. Second, the order of attitude degree in grade of students was 4, 6, and 5. The attitude toward children with disabilities showed statistically significant difference according to grade(F=3.546, p<0.05). Third, the attitude of students who have experience of contact with people with disabilities was non-significant compared to non-experienced students. Conclusion : In conclusion, therefore peer groups in lower class levels showed more positive attitude toward the children with disabilities. The result will be useful information for understanding disabled children and making positive attitude. Also it is expected that occupational therapists help disabled children to participate in school life successfully using these information.

Practical Performance of the 2015 American Thyroid Association Guidelines for Predicting Tumor Recurrence in Patients with Papillary Thyroid Cancer in South Korea

Lee, Seul Gi,Lee, Woo Kyung,Lee, Hye Sun,Moon, Jieun,Lee, Cho Rok,Kang, Sang Wook,Jeong, Jong Ju,Nam, Kee-Hyun,Chung, Woong Youn,Jo, Young Suk,Lee, Jandee Mary Ann Liebert 2017 Thyroid Vol.27 No.2

Effect of Optimum Nutrient Management on Productivity and Nitrogen Balance in Rice Cultivation: A Review

Seul-Bi Lee,Yang-Min Kim,Ye-Jin Lee,Yo-Sung Song,Cheol-Hyun Ryu,Deog-Bae Lee,Chan-Wook Lee,Chang-Hoon Lee,Jwakyung Sung 한국토양비료학회 2019 한국토양비료학회지 Vol.52 No.4

Given continuous needs for a public duty of agriculture and rural area, an effort to improve nutrient management in agricultural sector is strongly required. As a measure to solve these problems, Korean government (MAFRA) introduced the promotion policy called as “Agro-Environment Conservation Program (AECP)” in 2018 and has expanded 5 projet sites in 2019 from 3 in 2018. The program has a variety of agricultural activity to conserve soil, water, air, ecology and landscape. Of those, the nutrient input activity which is one of sub-activities is closely involved in not only crop productivity but also water quality and air pollution. Therefore, in order to lead a soft landing of AECP, it is essential to evaluate the conservation effects in a scientific point of view. In this respect, we focused on evaluating the effect of recommended nutrient input activities, standard fertilization and soil test fertilization, on rice productivity and nitrogen balance. The effect of nutrient management which is explained by rice yield and nitrogen balance was estimated with the combination of soil characteristics and rice varieties. Rice yield by recommended fertilization was 654 kg per 10a, 6% lower than control, but there was no statistical significance. By contrast, nitrogen balance was 4.7 kg lower, which means great improvement, in the recommended than the control. Conclusively, the recommended fertilization like soil test fertilization is expected to be useful as a measure to reduce nutrient balance, to ensure crop productivity, and finally to perform a public role of agriculture.

The Potency of Abamectin Formulations against the Pine Wood Nematode, Bursaphelenchus xylophilus

Jong-won Lee(Jong-won Lee),Abraham Okki Mwamula(Abraham Okki Mwamula ),Jae-hyuk Choi(Jae-hyuk Choi),Ho-wook Lee(Ho-wook Lee),Yi Seul Kim(Yi Seul Kim),Jin-Hyo Kim(Jin-Hyo Kim),Dong Woon Lee(Dong Woon L 한국식물병리학회 2023 Plant Pathology Journal Vol.39 No.3

Abamectin offers great protection against Bursaphelenchus xylophilus, a well-known devastating pathogen of pine tree stands. Trunk injection of nematicides is currently the most preferred method of control. This study aimed to evaluate the potency of the commonly used formulations of abamectin against B. xylophilus. Twenty-one formulations of abamectin were evaluated by comparing their sublethal toxicities and reproduction inhibition potentials against B. xylophilus. Nematodes were treated with diluted formulation concentrations in multi-well culture plates. And, populations pre-exposed to pre-determined concentrations of the formulations were inoculated onto Botrytis cinerea culture, and in pine twig cuttings. Potency was contrastingly different among formulations, with LC95 of 0.00285 and 0.39462 mg/ml for the most, and the least potent formulation, respectively. Paralysis generally occurred at an application dose of 0.06 μg/ ml or higher, and formulations with high sublethal toxicities caused significant paralysis levels at the tested doses, albeit the variations. Nematode reproduction was evident at lower doses of 0.00053-0.0006 μg/ml both on Botrytis cinerea and pine twigs, with significant variations among formulations. Thus, the study highlighted the inconsistencies in the potency of similar product formulations with the same active ingredient concentration against the target organism, and the need to analyze the potential antagonistic effects of the addi-tives used in formulations.