서울의 Penicillinase Producing Neisseria gonorrhoeae 발생빈도(1998)

김재홍,김준호,반재용,이정우,황성주,정준규,정성태,강진문,조흔정,홍창의,정혜신,이한승,김이선,이봉길,이종호,선영우,한기덕,윤성필,이성훈,안종성,박석범,문승현,조항래,김형섭,류지호,황재영,박준홍,손상욱 한양대학교 의과대학 2001 한양의대 학술지 Vol.21 No.1

In recent years, gonorrhea has been pandemic and remains one of the most common STDs in the world, especially in developing countries. For the detection of a more effective therapeutic regimen and assessing the prevalence of Penicillinase Producing Neisseria gonorrhoeae(PPNG), we have been trying to study the patients who have visited the Venereal Disease Clinic of Choong-Ku Public Health Center in Seoul since 1980 by menas of the chromogenic cephalosporin method. In 1998, 93 strians of N. genorrhoeae were isolated, among which 60(64.5%) were PPNG. The prevalence of PPNG in Seoul, which had been decreased to 39% in 1996 after a peak of 74.3% in 1993, is increased to 64.5% in 1998.

초소형 마이크로 부품 표면 측정 시스템 개발

홍성욱,고명준,신영현,이득우 한국공작기계학회 2005 한국공작기계학회 춘계학술대회논문집 Vol.2005 No.-

This paper proposes a measurement method for the surface of micro-parts by using AFM(Atomic Force Microscope). To this end, two techniques are presented to extend the capacity of AFM. First, the measurement range is extended by using an image matching method based on correlation coefficients. To account for the inaccuracy of the coarse stage implemented in AFM's, the image matching technique is applied to two neighboring images intentionally overlapped with each other. Second, a method to measure the shape of relatively large specimen is presented by using the inherent trigger mechanism due to the atomic force. The proposed method is proved effective through a series of experiments.

赤芍藥 藥鍼이 白鼠의 抗血栓 效果에 미치는 影響

洪儒聖,黃祐準 한국전통의학연구소 1998 한국전통의학지 Vol.8 No.2

This study was performed to prove the antithrombotic effects of paeonia japonica(赤芍葯, PJ) aqua-acupuncture solution by way of experimental methods. the thrombosis was induced by injection of collagen the mixture (0.1ml/10g, 2mg/kg B.W) plus serotonin (5mg/kg B.W) into the caudal vein of rats, 2 hours after liquid extract of paeonia japonica(PJ) was acupunctured into 'Taechung'(太衝:Liv3) of rats. The effect of aqua-acupunctures of paeonia japonica(PJ) was examined by the number of RBC and platelets, bleeding time, blood clotting time, death rate, platelet aggregation, plasma coagulation factor activity, exvivo and vitro fibrinolytic activity of englobulin fracture in the rats. The results were summerized as followings. 1. The number of RBC and platelets was significantly increased in PJ-treated group in comparison with the control group. 2. Bleeding time was significantly shortened in PJ-treated group in comparison with the control group. 3. Blood clotting time was significantly prolonged in PJ-treated group in comparison with the control group. 4. The death rate of mouse was inhibited in PJ-treated group in comparison with the control group. 5. The platelet aggregation was inhibited in PJ-treated group in comparison with the control group. 6. The prothrombin time and activated partial thromboplastin time on the test of plasma coagulation factor activity was prolonged but was not valuable in PJ-treated group. 7. Fibrinogen lyses time of rat was reduced and lyses area was increased in PJ-treated group in comparison with the control group. 8. Fibrinogen lyses time of rat in vitro assay was reduced in PJ-treated group. From the above results, it was thought that the aqua-acupuncture of PJ could be applied effectively in the thrombosis.

들깨 유전자원의 단백질함량과 지방 및 지방산 특성

홍성택,손석용,노창우,이경희,정재현,박재성 한국국제농업개발학회 2003 韓國國際農業開發學會誌 Vol.15 No.4

공시된 들깨 지방재래종 90개 품종의 단백질함량, 지방 및 지방산을 분석한 결과 다음과 같다. 1. 숙기별로는 중ㆍ만생종의 평균단백질 함량은 22.4%로 비교적 낮았고, 품종분포가 대부분 평균치에 가까웠으며, 조생종은 평균단백질 함량이 24.1%로 비교적 높았다. 2. 평균단백질함량은 소립종(천립중3.0~4.0g이하)이 23.0%로, 중립종(천립중 4.0~5.0g)이나 대립종(천립중 5.0~6.0g)의 22.1%보다 높은 경향이었다. 3. 기름함량은 조생종이 42.6%로 가장 적었고, 중생종이 44.5%, 만생종이 45.5%로 기름함량이 많았으며, 립중별로는 소립종이 44.2%, 중립종이 43.1%, 대립종이 41.5% 대립종일수록 낮은 경향이었다. 4. 지방산조성은 숙기가 늦어짐에 따라 Oleic acid와 Linolenic acid는 다소 많았고, Linoleic acid는 적어지는 경향이었다. Linoleic acid는 극대립종에서 15.5%로 가장 높았고 립중이 가벼울수록 높아지는 경향이었다. 5. 기름함량과 지방산 비율간의 상관 정도를 보면 기름함량과 Palmitic acid, Linoleic acid는 負의 상관이나, Stearic acid, Linolenic acid는 正의 상관을 보였다. Stearic acid는 Oleic acid와 유의적인 정의 상관을 , Linoleic acid와는 부의 상관을 보였다. Oleic acid는 Linoleic acid 및 Linolenic acid와 고도로 유의한 부의 상관을, Linoleic acid는 Linolenic acid와, 포화지방산은 불포화지방산과 유의한 부의 상관을 보였다. Korean local collected strains or varieties of perilla analyzed on their protein and oil content and fatty acids composition in the seed. The strains analyzed were 90 of which grown in the experimental field of Chungbuk Agricultural Research and Extension Services at Cheongwon and Umseong from 2001 to 2002. The seed protein contents of 90 perilla varieties ranged from 19.1% to 29.0% and the average content was 22.8%. There differed by the seed coat color showing 1.9% higher content in light gray than that of dark brown, which may suggest that the seed coat color could be used as a marker gene for breeding high protein varieties. Oil content of medium and late varieties in maturity showed higher as compared to early varieties, and appeared differences by seed coat color, and small seed varieties showed higher seed oil content than in large seed varieties by seed size. Linoleic and linolenic acid content of which major fatty acids in perilla seed were 74.4% in average of tested varieties. Fatty acid composition of perilla varieties were not significantly different by maturity, seed coat color and 1,000 seed weight. Oil content showed high positive correlation, with stearic and linolenic acids and negative correlation with linoleic acid.

영국에서 역사적 건물 보전과 반 파괴주의에 관한 연구

홍성우 경운대학교 산업기술연구소 2002 産業技術硏究論文誌 Vol.5 No.1(B)

The issue of historic preservation held no interest for the architects who pioneered and developed the modern movement. To them, the architectural theory of the modern movement was useful precisely because it helped them ot break free of the historical past and the theoretical tradition of earlier architecture. But in our own time, when preservation has assumed almost as great on urgency as the continued development of modernity, the theory of the 19th and the early 20th-century English architects about the preservation of old buildings have acquired new import and offer valuable insights to patrons and builders alike. Thus, this study investigated the 19th and the early 20th-century historic preservation and anti-scrape philosophy in England, and the contribution of John Ruskin and William Morris to the preservation process, so will it provide major resources on preservation theory and method to current architects.

글루콘산 생산을 위한 최적 배양조건

홍성란,이현절,정봉우,김춘영 全北大學校 1995 論文集 Vol.39 No.-

The production of gluconic acid by Aspergillus niger KCTC 2119 was studied. The Optimal culture conditions, such as initial pH, temperature, inoculum size and medium composition were established. Maximum overall gluconic acid productivity, 0.13g/L · hr was obtained when the cultivation was carried out at 33℃ and initial pH 5.5 for 72 hrs, with medium containing 110g/L glucose, 0.5g/L (NH_4)_2SO_4, 0.2g/L KH_2PO_4, 1.0g/L MgSO_4·7H_2O, and 0.1g/L corn steep liquor. The metabolic parameters such as specific growth rate, cell and gluconic acid yields were estimated for process improvement.

유럽건축가들의 역사적 건물 보전복구에 관한 연구

홍성우,이두진,이명권 경운대학교 산업기술연구소 2001 産業技術硏究論文誌 Vol.3 No.2(B)

The issue of historic preservation and restoration held no interests for the architects who pioneered and developed the modern movement. To them, the architectural theory of the modern movement was useful precisely because it helped them to break free of the historical past and the theoretical tradition of earlier architecture. In our own time, however, historic preservation has become multifaceted and the area of its involvement is constantly changed, and it has assumed almost as great an urgency as the continued development of modernity. As it has broadened its areas of activity and architect has played an important role in shaping the past and present of historic preservation and restoration, preservation research should focus its priorities and understand the limits of its resources in historic preservation and restoration process. In this study, therefore, the preservation and restoration principle of the 19th century European architects which were the main stream of historic preservation and restoration movement, was investigated from comparing there works and theories.

SMS를 이용한 경안천 하류구간의 하천흐름 분석

홍성민,정인균,이준우,김성준 한국지리정보학회 2004 한국지리정보학회지 Vol.7 No.1

본 연구는 경안천 하류구간(13.8㎞)을 대상으로 SMS의 RMA2 모형과 SES2D 모형을 이용하여 2002년 경안관측소의 최대홍수위를 기록한 8월 7일의 수리분석을 실시하였다. RMA2 모형을 적용하기 위하여 RIMGIS 데이터의 하천측량자료를 이용하여 입력자료로 활용하였으며, 생성돈 지형자료를 2차원 유한요소망으로 변환하여 모형을 수행하였다. 본 연구에서는 부정류 상태의 모의를 적용하였으며, 모형에 민감하게 반응하는 인자에 대해서는 선행 연구에서 실시한 민감도 분석결과를 고려하였고, 기타 입력인자는 통계연보 및 하천정비계획서를 참고하였다. 또한 대상하천에 SED2D 모형을 적용하여 홍수사상에 대한 하천의 하상 변동에 대한 모의를 실시하였으며, 대상 하천의 홍수시 유속은 0.05~3.85㎧의 분포로 상류와 하류의 큰 차이를 보였고, 하상변화는 0.0003~0.0135m가 발생하였다. The purpose of this study is to analyze various hydraulic characteristics using SMS(Surface Water Modeling System) RMA2 model. It is based on 2-D finite element method, River reaches (13.8㎞) from Gyeongan gauge station to the inlet of Paldang lake was selected. Finite element was made by RINGIS Data, and the analysis of river-changes was operated by unsteady flow. The sediment concentration and bed change was simulated using SED2D model. This River's velocity was distributed that 0.05~3.85㎧ and bed change was changed about 0.0003~0.0135m.

소아에서 발생한 골수이형성 증후군 2례

홍성진,윤석중,김성우,조형구,오명호,김기혁,이인성 건국대학교 의과학연구소 1996 건국의과학학술지 Vol.5 No.-

Myelodysplastic syndrome(MDS) is a group of acquired conditions characterized by progressive bone marrow failure associated with normocellular or hypercellular bone marrow that cannot be attributed to nutritional deficiency, chronic infection, or other chronic systemic illness, and cannot be reversed by the successful treatment of those conditions. Whereas the cases of secondary MDS occur at all ages, primary MDS is essentially a disease of elderly, though no age group is exempt and predomonant in men. The MDS is fundamentally clonal disorders at the level of the haemopoietic totipotent stem cell. Clinically, they are characterized by varing degrees of peripheral cytopenia(s) with morphological and functional abnormalities of blood elements. We have experienced two unrelated pediatric cases, who showed pancytopenia on admission and the characteristic marrow findings of MDS. The first case, a 12 months-old girl, showed increased reticulin with abnormal localization of immature precursor cells(ALIP) in her bone marrow, in addition to dysplastic features such as bi-and multi-nucleation of late normoblasts and internuclear bridging. She also showed 22% of blasts in her bone marrow cells thus classified in the category of RAEB-t after FAB classification. Also found were a chromosomal abnormality namely 46 XX t(14q21q), which was an unusual one. Her family brought her home and, 4 month later, she deceased. The second case, a 12 year-old boy, showed pancytopenia with Pseudo-Pelger-Huet anomaly in neutrophils but no blasts in the peripheral blood. Bone marrow of this case also showed the picture of dyserythropoiesis with binuclearity, internuclear bridging, nuclear fragments, multinuclearity of late normoblasts, in addition to megaloblastoid change in the normoblasts and increased mitosis in granulocytic series. No chromosomal abnormality was found. Classified as RA after FAB classification of MDS. Showed good response to conservative management for anemia for more than one year.

Euclid의 평행선 공준과 동치인 명제들

홍우철,홍성관 부산대학교 사범대학 2001 교사교육연구 Vol.40 No.-

In this paper we classify statements equivalent to Euclid's parallel postulate that appears in junior and senior high school math0texts, and give new proofs of them at the level of high school mathematics.