Bupivacaine과 ropivacaine이 Xenopus oocyte에 발현된 HERG 전류에 미치는 영향

김국성,이규승,김효신,손숙진,이상도,김광진,전병화,김윤희,박진봉 충남대학교 의과대학 의학연구소 2003 충남의대잡지 Vol.30 No.1

Bupivacaine is an amide-type local anesthetic widely used for regional anesthesia. Ropivacaine is developed as a less cardiotoxic alternatives to bupivacaine. In the present study, we have analyzed the effects of bupivacaine and ropivacaine on HERG currents expressed in Xenopus oocytes. Bupivacaine and ropivacaine(3∼1,000μM) blocked HERG currents in a concentration dependent manner. EC_(50) was 26.1±3.1μM(n_(R) 0.65±0.04) and 43.5±7.9μM(n_(H) 0.99±0.13) in bupivacaine and ropivacaine, respectively. Bupivacaine and ropivacaine did not affect the activation and deactivation kinetics of HERG channels. However, the drugs decreased the slope conductance measured from fully activated current-voltage relationship curves. These results suggest that bupivacaine and ropivacaine have a similarinhibitory effect on HERG channels, which could be a possible cellular mechanism of LQT or ventricular arrythmia by the drugs.

폐광미 조립분을 잔골재로 활용한 시멘트 경화체의 특성

윤성진,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.1(구조계)

Presently Metal-Mine waste is filled in the revertment, soil dike and undercurrent facilities of waste matter at piles, but this ways are not fundamental method of waste matter and it takes long time to maintain and it spends a lot of money so that we have need of a effective treatment plan and recycling method. In this study, to predict a effective treatment plan of Metal-mine waste(tailing) that is heaped. We observe tailing's physical and chemical basic features. According to examinate a hydration using tailing we evaluate its utilizable possibility as construction materials.

소화관내 이물에 대한 고찰

윤한덕,류진호,박주경,허탁,조석주,김성근,민용일 大韓應急醫學會 1997 대한응급의학회지 Vol.8 No.1

We analyzed records at Chonnam university hospital from Sep. 1. 1993 to Aug. 31. 1996 to assess clinical significance of the foreign body in the gastrointestinal tract. There were 133 episodes consisting of 79 pediatric and 54 adult patients as possible to review. In the pediatric patients, the coin was the most common cause of foreign body ingestion, while adult patients were usually caused by bones and meat. We removed foreign bodies in the oral cavity and oropharynx in 12 cases using direct laryngopharyngoscpy and forcep. Endoscopy was performed successfully in 47 of 51 patients in which was attempted; there were two complications composed of an aspiration pneumonia and a mediastinitis due to esophageal perforation. There were spontaneous passage of foreign bodies in 48 cases. We observed complications in 6 cases in which 4 cases needed operations due to complications. Foreign bodies which pass into the stomach can be observed for development of complications, as 94% of foreign bodies which reach the stomach spontaneously pass. Only 4 patients required interventions, which was done without mortality.

실업배구경기의 활성화 방안

진윤수,김용성 忠南大學校體育科學硏究所 2002 體育科學硏究誌 Vol.20 No.1

The porpose of this study is to define the best method which can make the professional games boom. The subjects were members of professional and university volleybell teams and the leaders of those teams and high school teams. To analyze the questions concerned with subjects' background. Frequency Analysis was used. To analyze the different views about 4PsC of players and leaders, T-test was used. ANOVA(analysis of variance) and T-test were used to analyze the different views about 4PsC according to subjects' background. Duncan's Multiple Range Test and Scheffe was used to study the similarities among all the group. The package used for this study was SAS(Statistical Analysis System) Program. The conclusion was as following: First, there was little difference between players' importance about Product, Place, Promotion, and Price and those of leaders' There were only some differences in customer management item. Second, there were a few differences about 4PsC according to four items of their background. 1) Only in Promotion, gender created some differences in the importance of 4PsC. 2) Only in Promotion, age made some differences in the importance of 4PsC. 3) In Product and Price, there were differences of 4PsC according to the subjects' educational background. 4) Only in Product, their background of carrer made difference of 4PsC.

충남대학교 기초과학분야의 효율적 육성에 관한 연구

윤화중,진성일,윤민중,윤혜수,이영하,최철규,이천배,신대현 충남대학교 자연과학연구소 1986 忠南科學硏究誌 Vol.13 No.2

Chungnam National University (CNU) is located in Daeduk Science Town, a center of science and technology in Korea, and it is expected to play an important role in the development of science in Korea. With this in mind, the basic natural sciences at CNU should be more actively supported in both education and research. Accordingly analysis and comparison of the basic science program at major college in Korea as well as those in the USA and Europe has been performed. The current cooperative relationship between CNU and research institutes in the science town has also been analyzed. This study has resulted in propositions to make more efficient the upbringing of the basic sciences at CNU, by focusing on the following points ; a) to improve academic affairs, b) to make graduate studies substantial, c) to secure highly qualified faculty members, d) to increase cooperation in research between CNU and reserch institutes, e) to enlarge research laboratories and acquire more equipment and facilities.

관개수심에 따른 벼의 생육 및 수량

윤성탁,전태웅,이동진 한국국제농업개발학회 2002 韓國國際農業開發學會誌 Vol.14 No.1

논토양에 있어서 관개수심에 따른 온도분포를 파악하고, 벼 재배에서 관개수심을 달리했을 때 수온과 지온의 온도환경변화와 이에 따른 수도의 생육 및 수량반응을 구명코자 실시한 시험결과는 다음과 같다. 우리나라 수원지방에서 수도재배기간 중 평균기온범위는 23.4∼29.1℃의 분포를 보였으며, 평균기온은 25.3℃이었다. 평균수온은 21.4∼26.7℃의 범위를, 지온은 21.7∼25.7℃의 범위를 보였으며, 수온 및 지온은 평균기온의 상승ㆍ하강에 따라 상승ㆍ하강하였다. 관개수심에 다른 생육특성을 보면 초장, 엽면적, 건물중 등은 처리간 차이가 없었다. 그러나 유수형성기는 12cm관개구에서 이앙 후 87일, 4cm구에서 83.3일이 각각 소요되어 관개수심이 깊을수록 유수형성기는 늦어지는 경향이었다. 수량 및 관련형질은 ㎡당 수수는 4cm관개구에서 413.3개/㎡로 가장 많았으나, 수당립수 및 ㎡당 입수는 오히려 8cm관개구가 각각 99.0개. 38,808개/㎡로 가장 많았으나, 관개수심별 정조수량은 대차 없었다. This experiments were carried out to evaluate the characteristics of temperature and the response of growth and yield characteristics under different irrigation depth in paddy rice field. Range of mean air temperature showed from 23.4℃ to 29.1℃ and mean of these air temperature was 25.3℃, while range of water temperature was from 21.4℃ to 26.7℃ and mean water temperature was 24.7℃. Range of soil temperature also was shown from 21.7℃ to 25.7℃ and mean temperature was 24.4℃ during growing periods of rice in Suwon. Plant height, leaf area index and dry matter were not shown difference among different irrigation depth, but date of panicle formation between irrigation depth showed difference such as that 12cm irrigation depth required 87.0 days while 4cm irrigation depth 83.3 days from transplanting showing that the deeper the irrigation depth, the later the panicle formation delayed. Number of panicles per ㎡ was shown highest in 4cm irrigation depth with 413.3/㎡, but 8cm irrigation depth showed higher number of grain per panicle and number of grain per ㎡ with 99.0, 2560.0/㎡ respectively. Unhulled rice yield among different irrigation depth showed no difference statistically.

폴리에스테르 모르타르용 충전재로서 금속광산 폐광미의 활용 연구

윤성진,최낙운,문경주,소양섭 대한건축학회 2003 대한건축학회 학술발표대회 논문집 - 계획계/구조계 Vol.23 No.2

The purpose of this study is to examine the basic properties of polyester mortars using fine tailing(FT) as a filler. The FT is obtained by centrifugal separation of tailing(TA), and checked for basic properties of shape, particle size distribution, chemical composition, resin absorption. Polyester mortars with FT and ground calcium carbonate(GC) are tested for working life, flexural and compressive strengths. The test results showed that FT has much the same properties as GC in the shape, size and resin absorption. The working life of the polyester mortars is lengthen with an increase in the filter/binder ratio. The polyester mortars with a filter/binder ratio of 1.0 have the maximum flexural and compressive strengths.

콘크리트강도 변화에 따른 RC기둥의 거동에 관한 연구

김성수,윤승조,이우진 청주대학교 산업과학연구소 2000 産業科學硏究 Vol.18 No.1

This study was evaluated the confined effect and ductility of core concrete on hoop reinforcement for grasping the behavior of reinforced concrete columns according to concrete strength through concrete strength parameter. The metamorphosis of hoop reinforcement was increased rectangular hoop reinforcement, longitudinal reinforcement, crossties in order with the strain increase. Especially, while after maximum strength, rectangular hoop reinforcement was burned and scattered the stress energy, longitudinal reinforcement and crossties were shown stress increase. The failure characteristics was gradually spalled the cover concrete after arriving to max main as small crack was sporadically progressed slowly in normal strength after occurring the early crack. Ratio of ductility was excellent the ductile ability that test specimens 1B5 and 2B5 were 48.5, but on the other hand increasingly with compressed strength, ratio of ductility was rapidly reduced speed that test specimen 4B5 was 10.58, 7B5 was 1.29 and 10B5 was 1.69, and finally shown the brittle failure. Ratio of ductility was excellent the ductile ability that specimens 1B5 and 2B5 were 48.5, but on the other hand increasingly with compressed strength, ratio of ductility was rapidly reduced speed that test specimen 4B5 was 10.58, 7B5 was 1.29 and 10B5 was 1.69 and finally shown brittle failure.

부산 서구 저탄소 녹색도시사업을 통한 지역환경 개선 및 활성화 방안 연구

정숙진, 윤성환, 우신구 신라대학교 부산학연구센터 2012 부산연구 Vol.10 No.-

전 세계의 환경문제인 기후변화에 적극적으로 대응하기 위해 새로운 국가 비전인 저탄소 녹색도시을 견인할 수 있는 지역·권역별 녹색도시화 특성화 방안을 제시함으로서 기후변화에 대응할 수 있는 방안을 모색하고자 한다. 부산 원도심인 서구 충무동·남부민동의 풍부한 자연자원과 다양한 역사·문화자원을 활용한 저탄소 녹색성장과 환경보호를 양립시켜 새로운 성장동력과 지역경제 활성화로 도시재생방안을 마련한다. 녹색기술을 활용한 경사지 주거재생, 도심형 항만재생, 원도심 상권재생의 3대 목표를 설정하고 6대 핵심 전략을 중심으로 지속가능한 녹색도시를 조성한다. 서구 저탄소 녹색도시 선도사업에서 노후화된 주거시설을 개선하기 위한 하우스 프로젝트을 통해 지역성에 맞는 주거모델을 제시하고 친환경 기술요소를 이용하여 자체에너지 생산, 그린 인프라를 이용하여 생태복원 및 바람길을 연결하여 미기후 조절을 가능하게 한다. 그리고 도심형 항만재생에서는 공동어시장에 발생하는 유기성폐기물을 바이오매스시스템 구축을 통하여 바이오에너지를 생산하며 해양친수공간 조성과 천마산을 연결하는 그린네트워크를 형성하여 부산의 대표적인 저탄소 녹색성장 명품도시로 조성한다. By suggesting the green city characterization measure for each region and zone that can lead the low carbon green city which is a new national vision in order to actively cope with the climate change, the global environment issue, we aim to seek for the measure to build up low carbon green city suitable for local characteristics. With low carbon green growth and environment protection by using abundant natural resources and various historical/cultural resources in Seo-gu Chungmu-dong and Nambumin-dong, the old downtown of Busan, the city reclamation measure can be prepared based on a new growth driving force and local economic vitalization. It is a general measure related to easing and adapting to climate change like water circulation, including setting up the three main goals like reclamation of residence on slopes, urban ports and business districts in old downtown based on green technology, and the six core strategies like establishing system of carbon reduction through using low carbon energy, improving the transportation structure through introducing green traffic system, having water/resource circulation system through low carbon circulation resource, having green construction system through applying green technology and environmentfriendly materials, building up ecotype greens based on the carbon absorption system through management of greens and urban forest and creating green community through private and public green partnership. It is possible to control microclimate by connecting wind ways, restoring ecology through using green infrastructure and producing its own energy based on environment-friendly technical elements as also suggesting residental models suitable for local characteristics based on the house project to improve obsolete residential facilities with low carbon green city leading project in Seo-gu. For the urban port reclamation, bio-energy is produced by building up biomass system through organic waste generated in the joint fish market. As also forming waterfront and green network connecting with Mt. Cheonma, it can be the representative low carbon green growth city in Busan.

부산의 해안지역 초고층 건물이 도시 풍환경에 미치는 영향에 관한 연구

박수진, 윤성환 신라대학교 부산학연구센터 2010 부산연구 Vol.8 No.1

본 연구는 우리나라의 대표적인 해안도시인 부산에 최근 등장한 해안지역의 초고층 건물들에 의한 도시의 풍환경의 영향을 검토하는 것을 목적으로 한다. 해운대구 마린시티 일대를 대상으로 CFD 시뮬레이션을 실시하였으며, 현재의 고층 저밀도로 가정한 모델을 비교 분석하였다. 계산 결과는 수평분포와 수직분포로 구분하여 그 영향을 검토했으며, 해안지역 초고층 건물에 의한 풍환경의 영향은 다음과 같다. 1) 풍환경은 건폐율보다 건물의 높이에 의한 영향이 더 크다. 기류의 수평분포와 수직분포 모두에서 고층건물에 의해 기류가 정체하는 영역이 넓어짐을 볼 수 있다. 2) 건물이 높을수록 도시 캐노피가 형성되는 지점이 높아진다. 저층건물 단지의 경우 건물높이의 약 1.5배 지점에서 도시 캐노피가 형성되었으나, 고층건물 단지의 경우 건물높이의 약 2.5배 지점에서 캐노피가 형성되었다. 도시 캐노피의 높이가 낮을수록 해풍도입을 통한 대류현열확산 효과가 높아지며, 이를 통한 도시 고온화 및 열섬현상 발생 억제에도 유리하다. 이러한 결과를 통해 해안에 인접한 지역에 초고층 단지를 계획할 때에는 이로 인한 도시 풍환경의 변화를 반드시 사전에 고려한 필요가 있음을 제고한다.