LiDAR 데이터를 이용한 수문지형인자 추출

김동문,김성훈,김의명 남서울대학교 2007 남서울대학교 논문집 Vol.13 No.4

Topographic parameter play an important role in determining the nature of water resources and related hydrological modelling.Recently, the research related in analyzing topographic parameter that which are required in hydrological analysis using GIS techniques is achieved.A watershed analysis tend to use a digital elevation model from LiDAR rater than that of extracted traditional map sheet.DEM quality and resolution affect the accuracy of any extracted hydrologic topographic parameters.Therefore, it is demonstrated that a LiDAR-derived DEM with high accuracy and high resolution offers the capability of improving the quality of watershed boundary extracted from DEMs. KeyWords : LiDAR, DEM, Topographic paramenter, Watershed

膈下逐瘀湯과 膈下逐瘀湯合四君子湯의 抗癌 및 免疫調節作用에 關한 實驗的 硏究

崔昇勳,安圭錫,文濬典,高光錫 대한동의병리학회 1994 동의생리병리학회지 Vol.9 No.1

연구배경 : 암은 사망의 주요 원인이 되는 질환으로 매년 증가하고 있는 추세이다. 이에 mouse에 암을 유발하여, 약물치료를 시행함으로써 높은 치료효과를 거두는 한약제재를 개발하여 암의 치료에 기여하고 아울러 근본적인 예방치료에 대한 새로운 방법을 제시하고자 함. 방법 : 생쥐에 Sacroma 180을 이식하여 복강암을 유발하고 격하축어탕 및 격하축어탕합사군자탕을 투여하여 생명연장률과 B cell 및 T cell, 혈청항체가, 임파구증식반응, IL-2 생산능 및 자연살해페소의 활성도를 측정하였다. 결과 : 격하축어탕과 격하축어탕합사군자탕은 면역조절작용을 통한 항암효과가 있을 것으로 생각되며, 활혈거어제인 격하축어탕과 보기제인 사군자탕을 합방했을때, 그 효과가 증가되었다. In order to investigate the effects of Gyeokhachukeotang and Gyeokhachukeotang plus Sagunjatang on anti-tumor and immunodulatory reaction to the ICR and C57BL/6 mice which have abdominal tumor after Sarcoma-180 cells were transplanted, the extracts of herbal medicines above mentioned were orally administered to the mice for 21 days to observe the extention of survival duration of the mice, quantitation of T cells and B cells, productivitiy of interleukin-2, lymphocytes transformation, hemagglutinin titer and hemolysin titer and activity of splenic natural killer cells. The results are summarized as follows; 1. In the effect of life extention, the Gyeokhachukeotang-medicated mice group inclined to show extended duration of life, which is of no great significant difference and the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang appeared to survive longer than the Gyeokhachukeotang-medicated mice group, which is not meaningful. 2. Considering T cell and B cell content, the Gyeokhachukeotang-medicated mice group had a meaningful increase in B cell (P<0.05) content, and the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang remarkably showed a significant increase in both T cell and B cell (P<0.01). 3. Considering serum antibody titer tended to increase in case of the Gyeokhachukeotang-medicated mice group, which is of no significant difference, while decreasing in case of the mice group medicated with mixture of Gyeokhachukeotang plus Sagunjatang. 4. In lymphocyte transformation marked a significant increase the Gyeokhachukeotang-medicated mice group, marked a significant (P<0.01), and remarkably showed a significant increase the mice group medicated with the mixture of Gyeokhachukeotang plus Sagunjatang (P<0.001). 5. As for the productivity of interleukin-2 and the activity of NK cells, the both tested groups inclined to show an increase or a decrese, but there is no significance.

Si 및 C이 첨가된 일방향응고 TiAl-Nb 합금의 파괴인성

김성용,오명훈,위당문 대한금속재료학회 2004 대한금속·재료학회지 Vol.42 No.3

The microstructure and mechanical properties of directional solidified Ti-47Al-3Nb, Ti-47Al-3Nb-0.2Si- 0.1C, Ti-47Al-3Nb-0.3Si-0.2C alloys were investigated. It was found that the lamellar thickness of Si and C doped alloys was fine and uniform, and little or no precipitates were found. Room temperature yield stress increased rapidly with increasing Si and C contents due to fine lamellar distribution and solid solution hardening. However, fracture toughness of type I specimens of the alloys decreased slightly with increasing Si and C contents. It was considered that α2 volume fraction decreased with increasing Si and C contents so that the delamination-type separation was decreased which contributes the high resistance of crack propagation for type Ⅰ specimens. Furthermore, fracture toughness of Ti-47Al-3Nb-0.2Si-0.1C alloy specimens with type Ⅰ orientation, polycrystalline form, and with type Ⅲ orientation increased in order of type Ⅲ, polycrystal and type Ⅰ. These results are discussed and the ability to obtain a respectable combination of strength and toughness through Si and C addition to a TiAl-Nb alloy produced by directional solidification is demonstrated.

Langmuir 이중탐침법에 의한 플라즈마 특성 진단

김성훈,서문규 청주대학교 산업과학연구소 2007 産業科學硏究 Vol.24 No.2

Plasma parameters of the remote, inductively-coupsad plasma system were measured by Langmuir double probe technical. Effects of the plasma power, reaction pressure on the electron density(n_(e)) and electron temperature(T_(e)) in the plasma were investigated. Electron dtlsities are measured in the range of 0.3∼6.5×10^(10)cm^(-3), and electron temperatures were in the range of 2∼7×10⁴ K. The electron dtlsity is increased with the plasma power and reaction pressure, but the electron temperature is found to be strongly deptldtlt on the reaction pressure rather than the plasma power.

심초음파로 결정된 응급 심낭천자술의 천자부위

김성환,황성오,이강현,조준휘,강구현,문중범,이승환,윤정한,최경훈,김영식 대한응급의학회 2000 대한응급의학회지 Vol.11 No.3

Background: The aim of this study was to determine whether the conventional subcostal approach is suitable for emergency pericardiocentesis in patients with cardiac tamponade or impending cardiac tamponade. Methods: This study was a prospective, observational study conducted at the emergency department of a tertiary hospital, Patients who had symptomatic pericardial effusion and who needed emergency pericardiocentesis in the emergency department were included in this study. We measured the epicardium-to-pericardium distance at the subcostal, parasternal, and apical area with two-dimensional echocardiography to determine the appropriate puncture site for pericardiocentesis. An epicardium-to-pericardium distance of more than 1.0 cm was considered as the primary safety factor in determining the Puncture site for pericardiocentesis. The skin-to-pericardium distance was considered as secondary safety factor. Results: Ninety-five consecutive patients(55 males and 40 females; total mean age: 53 year old) with cardiac tamponade or impending cardiac tamponade were enrolled in this study. The puncture site for pericardiocentesis, as determined by echocardiography, was the subcostal area in 43 patients(45%), the apical area in 40 patients(42%), the left parasternal area In 11 patients(12%), and the right parastemal area in one patient(1%). Pericardiocentesis failed in 2 patients(2%) with the subcostal approach and in one patient(1%) with the apical approach. The average epicardium-to-pericardium distance was 31 ±21 mm in patients with the subcostal approach and 21±8 mm in patients with other approaches. There were no differences in the amount of pericardial fluid and in the intraperical pressure among patient groups according to puncture site. There were two procedure related complications: a puncture of the right ventricle with the subcostal approach and a ventricular tachycardia with the apical approach.

7개 대학 병원에서 조사한 지역사회 폐렴의 원인균

정문현,김성민,강문원,최희정,정희진,이경원,한성우,송재훈,신형식,김의종,최강원,김민자,박승철,배현주,정윤섭,김준명,백경란,신완식,이규만,김양리 대한감염학회 1997 감염 Vol.29 No.5

목 적 : 폐렴은 많이 발생하면서 사망률이 크게 줄지 않는 질환이며, 이를 적절히 치료하기 위해서는 원인균의 상대적 빈도, 기저 질환에 따른 변화, 항균제 내성률, 사망에 관련된 인자들을 알아야 한다. 원인균의 빈도는 지역마다 차이가 있고 국내에서는 항균제 내성률이 높아 지역사회에서 발생한 폐렴을 치료하기 위한 경험적 항균제 선택에 도움이 되기 위해 서울 소재 6개 대학 병원과 천안의 1개 대학 병원이 참여하여 위의 사항들에 대해 조사를 하였다. 방 법 : 1995년에 내과에 입원했던 16세 이상 환자를 대상으로 했다. 퇴원 진단명이 폐렴 또는 폐결핵인 병록지을 찾았고, 이중에서 병원 감염을 제외하였다. 특이도를 높이기 위해, 이들 중에서 호흡기 증상이 있고 발열이나 저체온이 있으면서 흉부 X-선에서 이상 음영이 있는 환자만을 대상으로 했다. 폐결핵은 위의 기준에 입원 초기에 항균제 치료를 하고 입원 7일 이후에야 항결핵제가 투여된 경우만을 폐렴의 원인균으로 하였다. 혈액 배양에서 양성, 객담에서 항상균이나 M. tuberculosis가 증명된 경우, 혈청학적으로 항체가가 4배 이상 증가된 경우, 조직에서 원인균이 진단된 경우는 확정(definitive) 원인균으로 하였고, 객담에서 배양된 균이 그람 도말과 일치할때, 항결액제에 대한 반응으로 진단한 폐결핵, 단일 항체가 양성이고 이에 대해 항균제를 사용했을 때는 가능(probable) 원인균으로 정의하였다. 다세균 감염균은 각각 다 른 원인균으로 처리하였다. 임상 조사와 함께 임상병리과에서 S. pneumoniae, H. influenzae, M. catarrhalis, mycoplasma, 항상균에 대해 검사 의뢰 건수, 배양 양성수, 항균제 감수성 결과를 조사하였다. 결 과 : 폐렴의 증례 정의에 부합하지 않은 135명과 폐결핵의 정의에 해당하지 않는 230명을 제외하고 남은 246명의 평균 나이는 58.2세이고 남성이 142명(58.2%) 이었고, 71%의 환자에서 기저 질환이 있었다. 진단 방법의 시행 횟수는 혈액 배양 77.6%, 혈청 검사 18.3%, 기관지경 검사는 4.1%였고, 세균의 항원 검사를 한 예는 없었다. 원인균이 밝혀진 예는 77명(31.3%)이었다. 다세균 감염이 4명에서 있었고, 원인균의 상대적 빈도는 결핵 20명(확정 17, 가능 3: 6개 병원 자료), 폐렴구균 18(확정8 가능 10)명과 폐렴구균이 아닌 Streptococcus 3명 (모두 확정), H. influenzae 11명(모두 가능), 그람음성간균 11명(확정 7, 가능 4) (K. pneumoniae 8건), Mycoplasma 5명(확정 1, 가능 4), S. aureus 4명(확정 2, 가능 2), mucormycosis 1명(확정)이었다. 평균 입원 기간은 19일이고, 중환자실 입원률과 인공 호흡기 사용율은 각각 18%와 9.3%였다. 사망률은 13.8%였고 사망까지 평균 기간은 14.6일 이었다. 다변량 분석에서 사망을 예측할 수 있는 인자는 저체온과 빈호흡이었다. 임상병리과에서 배양되었던 모든 폐렴구균의 Penicillin 내성률은 서울 3개 병원에서 82-88%, 천안에서 72%였다. 폐렴 환자의 혈액에서 배양된 7주는 모두 Penicillin에 감수성이 있었다. K. pneumoniae 8주 모두 cefotaxime과 gentamicin에 감수성을 보였다. 결 론 : 후향적 조사이고 병원마다 원인균 진단에 차이가 있지만, 원인이 밝혀진 경우에는 결핵과 폐렴균이 흔하였고, 무균 부위에서 배양된 폐렴구균의 항균제 내성률은 낮았다. 원인이 밝혀지지 않은 경우가 많고, 혈청검사로 진단되는 원인균이 드물며, 분리균주가 적어 항균제 내성 정도를 추정하기 어려워, 이를 밝히기 위한 전향적 조사가 필요하다. Background : Community-acquired pneumonia (CAP) is one of the leading causes of mortality and morbidity, but its management is still challenging. The limitation of diagnostic methods to identify etiologic agents rapidly make it necessary to use empiric antibiotics in almost all patients, and furthermore the discovery of new respiratory pathogens and the emergence of antibiotic-resistant organisms pose difficulties to the selection of an empiric regimen. To clarify the factors necessary for the optimal choice of empirical antibiotics, such as the frequency of etiologic agents, the attributable rates to death and antimicrobial resistance rates in the community, six university hospitals in Seoul and one university hospital in Cheonan were participating in this study. Methods : medical records of adults (>15 years of age) hospitalized for CAP or pulmonary tuberculosis between April 1995 and March 1996, were reviewed. Patients who satisfied all of the following criteria were included in the study: (1) fever or hypothermia; (2) respiratory symptoms; and (3) pulmonary infiltrates on chest roentgenogram. To exclude cases of pulmonary tuberculosis whose roentgenographic features were so typical that it could be easily differentiated from conventional pneumonia, two additional criteria were required for inclusion: antibiotic treatment during the first week of hospital admission and initiation of anti-tuberculosis medications thereafter. Organisms isolated from sterile body sites, acid-fast bacilli or Mycobacterium tuberculosis isolated from sputum, pathogens diagnosed by a 4-fold rising titer of antibodies to “atypical”pathogens, or pathogens revealed by histopathology were defined as definitive cause of pneumonia; isolates from sputum withcompatible Gram stain, pathogens diagnosed by a single diagnostic titer plus use of a specific antimicrobial agent, or tuberculosis diagnosed by clinucal response to anti- tuberculosis medications were considered probable cause of pneumonia. The records of the clinical microbiology were reviewed for isolates of S. pneumoniae, H. influenzae, M. catarrhalis, Mycobacterium or acid-fast bacilli, and Mycoplasma. Then the frequency of these agents, antimicrobial resistance rates of resiratory pathogens from all body sites, and their clinical significance were evaluated. Results: After excluding 365 patients (230 with pulmonary tuberculosis and 135 with CAP) who were screened for inclusion but did not meet the inclusion criteria,246 persons were enrolled in this study. Their mean age was 58.2 years old with slight male predominance (58.2%), and 171(71%) patients had underlying illnesses. Blood cultures were performed on 191 (77.6%) patients and serologic tests on 44(18.3%) patients. The etiologic agents were identified in 31.3%, and the list of individual agents, in decreasing order, was pulmonary tuberculosis (17 definite and 3 probable: data of six hospitals), S. pneumoniae (8 definite and 10 probable), non-pneumococci (3 definite), aerobic gram-negative bacilli (7 definite and 4 probable), Haemophilus spp. (11 probable), mycoplasma (1 definite and 4 probable), polymicrobial infections (2 definite and 2 probable: E. coli and S. agalactiae, M. tuberculosis and S. aureus, S. pneumoniae and H. influenzae and A. baumannii and K. pneumonias), S. aureus (2 definite and 2 probable) , and mucormycosis (1 definite). Among gram-negative bacilli, K. pneumoniae was the most common agent (8isolates). therates of admission to the intensive care unitand of using assisted ventilation were 18% and 9.3%, respectively. The mortality was 13.8% and logistic regression analysis showed that hypothermia and tachypnea were associated with death. Hospital stay averaged 19 days. Susceptible rates of S. pneumoniae isolated from all body sites to penicillin ranged from 8% to 28% but seven isolated from blood of patients with pneumonia were susceptible to penicillin. Also all 8 isolated of k> pneumoniae from patients with pneumonia were susceptible to cefotaxime and gentamicin. Conclusion: In Korea, in addition to S. pneumoniae, M. tuberculosis is an important agent causing community-acquired pneumonia. The low incidence of etiologic diagnosis is probably related to infrequent requesting of test "atypical" pathogens and does not represent the true incidence of infections by "atypical" pathogens, which well be answered by a prospective study. The antimicrobial resistance rates of major respiratory pathogens from sterile body sites are low, however, because of a small number of the isolates this result needs confirmation by a nationwide surveillance of antimicrobial resistance.

압박 고 나사로 치료한 대퇴골 전자부 골절 : 고정 실패의 인자에 대한 분석 Analysis of Factors associated with Failure of Fixation

유찬훈,김홍태,변영수,남준모,조영호,문성건 대한골절학회 2002 대한골절학회지 Vol.15 No.4

목 적 : 압박 고 나사로 치료한 대퇴골 전자부 골절의 고정 실패에 영향을 미치는 요소에 대하여 분석하고자 하였다. 대상 및 방법 : 1995년 5월부터 2000년 7월까지 대퇴골 전자부 골절을 압박 고 나사를 이용하여 치료하고 1년 이상 추시가 가능했던 97예를 대상으로 하였다. 골절의 분류는 Jensen 분류법을, 골다공증의 정도는 Singh 지수를 이용하였다. 술후 방사선 검사에서 경체각, 정복 상태, 지연 나사의 대퇴골 두 내 위치, tip-apex distance(TAD) 및 지연 나사의 활강 거리를 측정하였고 고정 실패에 미치는 영향을 통계학적으로 분석하였다. 결 과 : 97예 중 17예(17%)에서 고정 실패가 발생하였고 그 중 지연 나사의 과도한 활강으로인한 경우가 15례(15.4%), 골두 천공 1얘, 10도 이상의 외반 변형 1예였다. 고정 실패의 발생과 80세 이상의 고령, 불안정성 골절, telescoping 정복, 원위 골편의 내측 혹은 전방 전위, 대퇴골 두 내 지연 나사의 위치와 밀접한 관계가 있었다. 결 론 : 압박 고 나사를 이용한 대퇴골 전자부 골절의 치료에서 고정 실패를 방지하기 위해서는 정확한 정복이 필요하고 대퇴골 두 내에서 지연 나사의 전방 위치를 피하는 것이 좋을 것으로 사료된다. Purpose : This study was performed to analyze the significant factors that may affect failure of fixation in trochanteric fractures of the femur treated with the compression hip screw. Materials and Methods : From May 1995 to July 2000, the authors analyzed 97 cases of trochanteric fracture of the femur treated with the compression hip screw and followed more than one year. We classified the fracture type by Jensen's method. We used Singh index for the degree of osteroporosis. In the post-operative radiograph, we checked neck-shaft angle, state of reduction, position of the lag screw within the femoral head, tip-apex distance, and sliding distance of the lag screw. The relationship between these factors and failure of fixation was statistically analyzed. Results : There were 17 cases(17.5%) of failure of fixation ; 15 cases(15.4%) of excessive sliding of the lag screw, 1 case (1%) of cutting out of the lag screw, and 1 case (1%) of valgus malunion. There were significant relationship between failure of fixation and old age over 80 , unstable fracture, telescoping reduction, anterior or medial displacement of the distal fragment, and anterior placement of the lag screw within the femoral head. Conclusion : Accurate reduction and avoidance of the placement of the lag screw in the anterior part of the femoral head were important factors to prevent failure of fixation in trochanteric fractures of the femur treated with the compression hip screw.

강릉시내 자전거 전용도로개설의 타당성에 관한 설문조사 분석

정문선,백남훈,이창수,윤신 강릉대학교동해안지역연구소 1994 東海岸硏究 Vol.5 No.1

본 논문에서는 강릉시내에서의 자전거 전용도로 개설에 관한 타당성을 조사하기 위햐여 지역주민을 대상으로 설문조사를 실시하였으며 그 결과를 분석하였다. 설문내용에는 현재 자전거 이용실태, 자전거 전용도로 개설의 타당성, 노선등을 포함하였다. 설문조사결과 자전거 전용도로 개설에 관해 긍정적 답변이 많았다. We make up the questionaire for the validities of establishing the bicycle-way in Kangnung, and analyze the results. The contents of the questionaire include the research on actual state of using one's own bicycle, the validities of establishing the bicycle-way, and the routes. The results of the questionaire show the affirmative answer for the establishing the bicycle-way in Kangnung.

NiAl/Ni₃Al 2상 합금의 상변태 및 미세조직에 미치는 제3원소 첨가효과

송성훈,김수현,오명훈,위당문 대한금속재료학회 2003 대한금속·재료학회지 Vol.41 No.12

The microstructural evolution of b-NiAl/γ' -Ni3Al two-phase (Ni_(66)Al_(34))_(100-x)X_(X)(X=Ti, Si, Nb) alloys during various heat treatment (quenching and aging) were systematically studied. It was found that the microstructural features of the two-phase NiAl/Ni₃Al alloys could be divided into three types : lamellar, mesh and Widmansttten microstructures. The reason why those three types of microstructure were formed could be explained by the change of austenite start temperature(As temperature) depending on the ternary elements. In case of As>250℃, the lamellar microstructure was formed by following phase transformation: Martensite→Ni5Al3→β+γ' . In this case, the NiAl martensite was quickly transformed into the Ni5Al3 phase at 250℃ by a re-ordering reaction. In case of 20℃ <A_(s)<250℃, two types of mesh microstructure were formed depending on the ternary element. When Ti and Nb were added as a ternary element, the β→Ni_(5)Al3 transformation occurred very quickly, but not in the case of Si addition. Hence, the final mesh microstructures showed somewhat different microstructural features. On the other hand, in case of A_(s)<20℃, the direct β→β+γ' transformation occurred because the martensitic transformation could not occur due to its very low M_(s) temperature, resulting in the Widmanstatten type microstructure.

α상분율의 변화가 층상조직 TiAl 합금의 열적안정성에 미치는 영향

金聖雄,이호년,吳明勳,山口正治,韋當文 대한금속재료학회 2002 대한금속·재료학회지 Vol.40 No.6

The thermal stability of lamellar microstructure in TiAl-Mo PST crystals containing C or Si was investigated. In addition, the variation of α-phase volume fraction in Ti-Al-Mo-(C, Si) systems was also investigated at several temperatures. It was found that Ti-46Al-1.5Mo-O.2C and Ti-46Al-1.5Mo-1.0Si alloys were very stable during heat treatments at various heating rates and temperatures. Moreover, the, α-phase volume fraction of Ti-46A1-1.5Mo-0.2C and Ti-46A1-1.5Mo-1.OSi alloys (stable composition) was less changed than those of Ti-47Al and Ti-46Al-1.5Mo alloys (unstable composition). From these results, the instability of the latter alloys was thought to be resulted from relatively higher variation of α-phase volume fraction during heating. Therefore, it could be suggested that the variation of α-phase volume fraction is an important factor that control the thermal stability of lamellar microstructure.