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      • KCI등재

        Prediction of Retained Austenite Fraction in Quenching-and-Partitioning (Q&P) Steels Using the Gibbs Energy Balance Approach

        Seong Hoon Kim,Ji Hoon Kim,Jae Hoon Lee,Dong‑Woo Suh,Jae Sang Lee 대한금속·재료학회 2022 METALS AND MATERIALS International Vol.28 No.9

        Prediction of retained austenite fraction is quite important in designing advanced high strength steels since retained austeniteis the source of transformation-induced plasticity. The present study investigates the phase constitution of a medium-carbonQ&P steel by comparing various approaches to the transformation stasis of bainitic ferrite and applying them to the partitioningprocess. Among them, the modified GEB approach gave the best agreement with the experimental observation, includingthe effects of heat-treatment condition and chemical composition on phase constitution. This indicates phase transformationduring partitioning can be effectively described by the physics of Gibbs energy balance approach.

      • KCI등재

        혈액암환자에서 조혈모세포 이식 후 따르는 헤르페스 바이러스 감영 양상

        이호섭,탁희상,신성훈,김양수,남성진,김혜수,박진희,정수현,김성빈,김예나 고신대학교 의과대학 2010 고신대학교 의과대학 학술지 Vol.25 No.1

        배경 : 헤르페스바이러스과에는 단순포진 바이러스(HERPES SIMPLEX VIRUS, HSV), 수두대상포진 바이러스 (VARICELLA-ZOSTER VIRUS, VZV), 엡스타인-바 바이러스 (EPSTEIN-BARR VIRUS, EBV), 그리고 거대세포 바이러스 (CYTOMEGALOVIRUS, CMV) 등이 있다. 헤르페스바이러스 감염은 혈액암환자에서 조혈모세포 이식 환자에서 전파 (dissemination), 이차감염, 세균 중복 감염의 심각한 합병증을 일으킬 수 있다. 하지만 항암약물치료를 받는 림파종 환자에서 항 바이러스 약제의 사용 용량과 기간에 대한 concensus는 없다. 헤르페스바이러스 감염에 대한 발생율과 위험인자를 후향성으로 분석하였다. 방법 : 고신대학교 복음 병원에서 1995년 6월부터 2009 년 2월 사이에 새롭게 진단되어 조혈모세포 이식을 받은 전체 58명의 환자들이 후향적으로 현 연구에 등록했다. 헤르페스 바이러스 감염은 임상적 진단, 혈청학적 검사 또는 병리학적 진단에 기초하여 확진한다. 환자들의 특성은 다음과 같다: 평균 연령은 44세 (범위 19-62세)였고 남녀비는 30:28이었다. 등록된 질환은 백혈병 (n=9, 15.5%), 림프종 (n=30, 51.7%), 다발성 골수종 (n=12, 20.7%), 재생불량성 빈혈 (n=6, 10.3%) 그리고 골수이형성증후군 (n=1, 1.7%)이 포함되었다. 결과는 chi-squre test나 independent samples T test를 사용하여 분석되었다. Multivariate analysises에 대해 logistic regression test를 사용하였다. 결과 : 15명의 환자들 (25.9%)에서 조혈모세포 이식후 헤르페스 바이러스 감염이 발생하였다. 조혈모세포 이식 5년간 누적 발생율은 53.9%였다. Univariate analyses에서 헤르페스 바이러스 감염에 대한 유의한 위험 인자는 없었다. 하지만 조혈모세포 이식후 생존 기간(40.18 ± 30.14 months vs 20.06 ± 26.67 months, p=0.018)은 헤르페스 바이러스 감염의 낮은 발병율과 유의한 관련성이 있었다. 이식 편대 숙주질환 (GVHD)의 존재 (37.5% in developed GVHD vs 0% in no GVHD, p=0.200), 동종조혈 모세포 이식에서 면역억제요법의 기간 (15.98 ± 14.02 months vs 6.78 ± 3.67 months, p = 0.374)은 헤르페스 바이러스 감염에 대한 위험인자가 아니었다. 결론 : 조혈모세포 이식 후 생존 기간은 어사이클로비어 예방을 받은 혈액암 환자에서 헤르페스 바이러스 감염의 낮은 발병율과 연관성이 있는 것으로 보인다. 저용량의 어사이클로비어 예방은 헤르페스 바이러스 감염의 고위험군인 조혈모세포 이식을 받은 혈액암 환자에 필요하리라 생각된다. Background : Herpesviridae family includes herpes simplex virus, varicella zoster virus, Epstein-Barr virus, and cytomegalovirus, etc. Herpesviridae viral infection (HVI) can lead to serious complications including dissemination, secondary infection, bacterial superinfection in patients with hematologic malignancy following hematopoietic stem cell transplantation (HSCT). But there was no consensus on the dose and duration of antiviral agents prophylaxis in patients undergoing chemotherapy. We retrospectively analyzed the incidence and the risk factors for HVI. Method : A total of 58 patients who newly diagnosed and received HSCT with prophylaxis of acyclovir at the Kosin University Gospel Hospital, Busan, Korea between June 1995 and February 2009 were enrolled retrospectively in the current study. HVI was confirmed based on clinical diagnosis, serologic test or pathologic diagnosis. The characteristics of the patients were as follows: the median age was 44 years (range 19-62 years) with a female-to-male ratio of 30:28. The enrolled diseases included leukemia (n=9, 15.5%), lymphoma (n=30, 51.7%), multiple myeloma (n=12, 20.7%), aplastic anemia (n=6, 10.3%) and myelodysplastic syndrome (n=1, 1.7%). The results were analyzed using a chi-square test and independent samples T test. For the multivariate analysis, we used logistic regression test. Results : Fifteen patients (25.9%) developed HVI after HSCT. The cumulative incidence of HVI was 53.8% at 5 years after HSCT. In univariate analysis, there was no significant risk factor for HVI. The presence of graft-versus-host disease (GVHD) (37.5% in developed GVHD vs. 0% in no GVHD, p=0.200), duration of immunosuppressive therapy (IST) in allo-SCT (15.98 ± 14.02 months vs. 6.78 ± 3.67 months, p = 0.374) were not risk factors for HVI. Conclusion : The incidence of HVI was similar to that in historical other studies. There was no risk factor associated with development of HVI. Most of the HVI occurred within the first 24 months after transplantation. So long term use of antiviral prophylaxis may be needed to prevention of HVI after HSCT.

      • KCI등재

        격투스포츠 선수의 스포츠맨십 분석

        박태훈(Park Tae-Hoon),유기성(Yoo Ki-Seong),유원용(Ryu Won-Yong),김영욱(Kim Young-Wook),이양구(Lee Yang-Gu),공창빈(Kong Chang-Bin),이상호(Lee Sang-Ho),김태영(Kim Tae-Young) 한국체육과학회 2010 한국체육과학회지 Vol.19 No.3

        This research examines whether difference that is some in inclination of combat sports player's sportsmanship is, and accordingly is purposeful to clear relation. combat sports (fencing, Taekwondo, boxing, induction, wrestling, wrestling) player who research target is having player life in middle·high·an university 399 people be . Used Korean-made measure (KMSOS) that Seong-changhun (2003) verifies changing based on Vallerand MSOS by a tool to measure sportsmanship of players. Data processing used SPSS 12.0 programs. Did reliability analysis that use Cronbach'a coefficient to verify believability of an irradiation tool, Difference of sportsmanship used t-test, one-way ANOVA. In this research, drew following conclusion. First, man appeared higher level than woman in wave and human desire, decision respect, and woman appeared higher level than man in victory or defeat excessive fondness. Second, exercise immersion, decision respect, victory or defeat excessive fondness appeared level that minority is taller than majority. Third, in exercise immersion high school player decision respect appear, and tendency of level that middle school playing the first stone is high in victory or defeat excessive fondness appeared. Fourth, striking radical type of player appeared higher level than Geuraepeulring type of player in companion respect factor. Fifth, player less than exercise career 4 years appeared higher level than player less than 7 years and player more than 7 years for victory or defeat excessive fondness factor. Sixth, Taekwondo for best and companion respect factor, high level appeared to boxing item players.

      • 한의진단명과 진단요건의 표준화 연구 III : 3차년도 연구결과 보고

        최선미,양기상,최승훈,박경모,박종현,심범상,김성우,노석선,이인선,정진홍,이진용,김달래,임형호,김윤범,박성식,송태원,김종우,이승기,최윤정,신순식 한국한의학연구원 1997 한국한의학연구원논문집 Vol.3 No.1

        The diagnostic requirements were suggested and explained regarding the systems of differentiation of symptoms and signs in the third year study of standardization and unification of the terms and conditions used for diagnosis in oriental medicine. The systems were as follows : - analyzing and differentiating of epidemic febrile disease - analyzing and differentiating in accordance with the Sasang constitution medicine based on four-type recognition - differentiation of disease according to pathological changes of Chong and Ren channels - standards for diagnosis of women's disease - standards for diagnosis of children's disease - standards for diagnosis of motor and sensor disturbance (-muscle. born, joint, etc.) - standards for diagnosis of neuropsychiatric disease - standards for diagnosis of five sense organ disease - standards for diagnosis of external disease The indivisual diagnosis pattern was arranged by the diagnostic requirements in the following order : another name, notion of diagnosis pattern, index of differentiation of symptoms and signs, the main point of diagnosis, analysis of diagnosis pattern, discrimination of diagnosis pattern, prognosis, a way of curing a disease, prescription, herbs in common use, disease appearing the diagnosis pattern, documents. The standards for diagnosis of each disease was arranged by the diagnostic requirements in the following order : another name, notion of disease, the main point of diagnosis, analyzing and differentiating of disease, analysis of disease, discrimination of disease, prognosis, a way of curing and prescription of disease, disease in western medicine appearing the disease in oriental medicine, documents.

      • 용혈성 요독 증후군이 합병된 출혈성 장염 1예

        김능수,이원길,김기연,이종명,윤종수,김성한,전정훈 대한감염학회 1997 감염 Vol.29 No.3

        저자들은 쇠고기에 의해 매개된 것으로 추정되는 출혈성 장염 및 이에 합병된 용혈성 요독 증후군 환자 1예를 경험하였기에 문헌고찰과 함께 보고하는 바이다. We report case of hemolytic uremic syndrome(HUS) associated with hemorrhagic colitis. A 35-year0old man was admitted to a local hospital because of abdominal pain and watery diarrhea which had developed about 6 hours after taking roast beef. He was treated with intravenous fluids and antibiotics, but watery diarrhea changed to bloody in nature from the next day. He was transferred to our hospital due to progressive ascites and jaundice on his 8th day of illness. Examinations revealed ascites, jaundice, microangiopathic hemolytic anemia, thrombocytopenia and uremia. Sorbitol-negative Escherichia coli was isolated from his stool, which proved as Shiga-like toxin-negative E. coli, serotype O25. His conditions improved markedly after three times of plasmapheresis and intravenous fluids therapy, and the organism was not isolated from the follow-up stool culture.

      • 醫療過誤의 刑事責任

        金成勳 제주한라대학 1976 論文集 Vol.2 No.-

        1. The doctor's act of medical treatment is an important business dealing with human life and the doctor should treat patients with his professional medical knowledge, experience and the well-eqipped medical facilities. However, it is unreasonable that he should be legally responsible for the faults in his medical treatment, based upon only the results, with nothing of the proccess considered at all. There have been truly the various kinds of unfortunate results unexpected in the treatment process, not withstanding his professional experience and ability because the organization of the human body differs from the mechanism of things. Therefore it is desirable that he should be legally guarenteed in performing the medical act with relief and conviction. 2. Malpractice means bad, wrong, or injudicious treatment of a patient, Professionally and in respect to the particular disease or injury, resulting in injury, unnecessary suffering, or death to patient, and poceeding from ignorance, carelessness, want of proper professional skill, disregard of established rules or principles, neglect, or a malicious or criminal intent. 3. Though the criterion for decision of the negligence in the medical accident can not be uniformly regulated, the generally accepted one ought to depend on the facilities and the skill normal to the average reffered to the regional difference and emergency. 4. There seem to be many types in differentiating the malpractice. At first, from the view point of the difficulty of recognition of the negligence, there are two types. One is the comparatively simple technical treatmenton which there are likely to be very few disputes-errors from shots, medicines and the aftermath of operations. The other is the one from the medical misjudgement-an erroneous diagnoses. In this point, many problems in recognizing varied medical errors are deliberately illustrated here. Some problems caused from handling the unusual constitution and from taking care of patients unfaithfully are also stated here. 5. As the number of the cases of procedure on the medical negligencs has increased in recent years, the legitimacy of medical behaviors which has been neglected for the time being seems to attract attention from the various fields of jurisprudence and medicine, encouraged by the progress in their remarkable studies. Even though the medical skill have remarkably developed, there have been always the possibilities that the unexpected misfortunes from medical negligence may happen at any time. And it cannot be emphasized too strongly that the proper and reasonable harmonious points should be established to proceed legal settlement between the security of human right the patients' sake and the legal guarentee for the medicine men in cases of negligence. Thus it is strongly requested that a tentative study and many other precedents on both sides from the related fields should be made for the legitimacy of medical doctors' act for the protection the patients' human rights from malpractice.

      • 醫藥品의 安定性에 關한 硏究 (第3報) : Sulpyrin 水溶液의 安定性에 關하여 The Stability of Sulpyrin in Aqueous Solution

        金鍾秀,金壽億,徐成勳 慶熙大學校 1983 論文集 Vol.12 No.-

        The pharmacokinetic study of solution was conducted to determine the stability of sulpyrin. The powder was added with diluents and stored under three different conditions to determine the humiditification weight and degradation rate. The solution of sulpyrin indicated first order reaction and t_90 was 82 days at 25℃. When the powder was stored under the three different conditions, the avicel mixture showed the highest humiditification weight, while the only sulpyrin showed the highest degradation rate under the relative humidity of 75% and 92% followed by the avicel mixture. The starch and lactose mixture showed the lowest similar humiditification weight and degradation rate. Therefore, it seems that the stability of the main ingredient will be greatly influenced by the diluents.

      • 環境權의 展開와 確立

        金成勳 제주한라대학 1980 論文集 Vol.6 No.-

        This article attemps to make a legal approach to inquire into some environmental problems from the viewpoint of the establishment of environmental right. Therefore, this article aims to establish the right by examining the background, development and the theory of environmental law. The effects of environmental right limit their range to those of legislation and administration. As the aspect of today's environmental pollution or devastation is complicated and diversified, the environmental problems are becoming more serious and have outgrown the function of the conventional civil law principle. This is why the conventional law principle has to be corrected and give rise to the need of environmental right. This right will make possible the pleasant environment and a healthy life in it. This is an inborn, individual right as the fundamental human right. This right to protect the environment from devatation and pollution rests on the ideology of the superiority of human being over economy and on the absoluteness of the protection of the human being's health. Therefore, this environmental right can be said to be the one to make possible a lawsuit only with the regulations of Constitution. The approval of the environmental right works as a guiding doctrine for the preservation of a healthy and delightful environment in the aspect of the effects of legislative policy of environmental pollution. As a result of the comprehension of law principle, this approval of environmental right offers some ground for the obligatory suit in the administrative litigation, and for the request of the compensation for damage resulted from the violation of the environmental right. But, in fact, the legistative or administrative power is no longer able to cope with the environmental problems, neither helpful is the juridical relief to their solution owing to its restrictions. Thus the future of the environmental right has no other choice but to be development positively on the legislative or administrative measure inclusively considering the preservation and recovery of environment the welfare and health of the individual resident. So far as the juridical relief is concerned, ahead lies the task to construct the new legal technique for the preseration and recovery of environment.

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