특정 세균으로 유도된 백서의 치수염에서 T 세포 아군집의 분포와 interleukin-2, interferon-γ, interleukin-4의 수준에 관한 연구

김선아,임성삼 大韓齒科保存學會 2002 Restorative Dentistry & Endodontics Vol.27 No.1

Immune response associated with bacterial infection involve inflammatory cells. Clinical symptoms and pathologic features are particularly influenced by the predominant cells. Among inflammatory cells. T cells have the heterogenity. T cells may develop into the mature cell expressing the cell surface markers with different functions and T helper cells are categorized into Th1 and Th2 cells based on their different patterns of cytokine production. The objective of this study was to investigate the change of expression of surface markers on T cells and the Th1/Th2 immune response in pulpal inflammation associated with specific bacteria. We experimentally induced pulpal inflammation in rat incisors by drilling without coolant and innoculated with Streptococcus mutans (S.M. group), Porphyromonas endodontalis (P.E.group), or only sterile cotton (control group). After 1, 2, and 5 days, mandibular incisors were extracted and the pulptissues were extirpated. The expressions of IL-2 recepters (CD25) and ICAM-1 (CD-54) on CD4+ and CD8+ cells in the pulps were determined using a flow cytometer, and the concentration of IL-2, IFN-γ, and IL-4 was measured by enzyme-linked immunosorbent assay. The results were as follows; 1. In the S.M.group. CD4+ cells were more increased at 2nd day than 1st day and in the P.E.group, CD8+ cells were more increased at 2nd day than 1st day. 2. The percentages of CD4+, CD4+25+ and CD4_54+ cells were decreased in the pulp tissues at 5th day after irritation in all groups. 3. The ratios of CD4+/CD8+, CD4+/CD4+25+ and CD4+/CD4+54+ in the pulps at 2nd day after irritation by P.endodontalis were significantly lower than the other groups. 4. The higher concentrations of IFN-γ than IL-4 in the pulps at 2nd day after irritation by P.endodontalis showed that T helper 1 reaction were predominant in the early stage of the pulpal in flammation induced by P.endodontalis. 5. The higher concentrations of IL-4 than IFN-γ in the pulps at 1st day and 5th day after irritation by S.mutans were measured but the differences were not significant.

팔라디움 촉매하에서 산염화물과 유기주석의 커플링 반응

김두화,박정환,한도수,허선아,김성현,조성동 조선대학교 기초과학연구소 1992 自然科學硏究 Vol.15 No.1

The reaction of Asymmetrical organotins with acid chlorides in the presence of Benzylbis (triphenylphosphine) palladium(Ⅱ) chloride gave good yields of ketones in chloroform.

유세포분석기를 이용한 정상치수조직과 염증성 치수조직 내의 임파구 분포에 관한 연구

김선아,배광식,임성삼 大韓齒科保存學會 1997 Restorative Dentistry & Endodontics Vol.22 No.1

韓中 통번역에서의 동사 `하-' : `이음절 한자어+하-'를 중심으로 Focused on `sino Korean word+ha-'

김선아 한국국제회의통역학회 2004 통역과 번역 Vol.6 No.2

The verb ‘ha-’ in Korean is a common verb that is used very frequently. It has various syntactic functions like a main verb, a dummy verb (light verb), and a pro-verb. This study investigates the various aspects of Chinese verbs that are corresponding with ‘ha-’ while interpreting and translating between these two languages. It will be helpful to form the equivalence in interpretations and translations. ‘ha-’ in source language (Korean) can arrive at different verbs in target language (Chinese). In many cases, it corresponds with ‘zuo(作)’. In other cases, one may raise a question in argument whether it should be handled like ‘objective+ha-’ as a specific lexicon or an idiom. Even though ‘ha-’ is used so widely in interpreting and translating, there was no study until yet. Through the investigation about the interpreting and translating examples, we can find there is the tendency that ‘ha-’ in Korean(SL) can be translated into dummy verb in Chinese(TL).

검은비늘버섯의 포장재와 저장온도에 따른 저장 효과

김기식,주선종,윤향식,김민아,박성규,김태수 한국식품저장유통학회 ( 구 한국농산물저장유통학회 ) 2003 한국식품저장유통학회지 Vol.10 No.3

본 연구는 검은비늘버섯((CBPM-6호)의 선도유지 효과를 알아보기 위해 포장재(Wrap, PE, PP, AF) 및 저장온도(1℃, 3℃, 6℃)을 달리하여 18일간 결과를 다음과 같다. 저장기간 중 포장재별 중량 감모율은 랩 포장시 1℃에서 18일 후 3.17%이었으나, AF필름에서는 1.08%의 낮은 중량 감모율을 나타내었다. 색도는 저장기간이 연장될수록 명도와 황색도는 약간 증가하는 반면 랩 표장에서는 감소하는 경향을 나타내었다. 버섯 저장 전 색깔은 랩 포장에서는 3일, PE, PP, AF포장지에서는 18일까지 유지되었다. 경도는 저장온도가 높을수록 낮아지는 경향이었으며 1℃에서 저장할 때 AF 밀봉 저장이 경도의 변화가 가장 적은 것으로 나타났다. 신선도는 1℃ 저장시 신선도 8을 기준으로 랩 포장은 3일, PE 밀봉은 6일, PP 밀봉은 9일, AF 밀봉으로 15일간 저장시 상품성을 유지할 수 있다. This study was carried out to develop storage method for the keeping freshness with various packing film(Wrap, PE, PP and AF and storage temperature(1, 3 and 6℃) of Pholiota adiposa(CBPM-no6) mushroom. The rate of weight loss packed with Wrap film was 3.17%, but AF film was 1.08% after 18days. As the storage periods, lightness and yellowness of mushroom packed with PE, PP and AF were slighty increased, while Wrap film was decreased. The color of original raw mushroom preserved 3days using Wrap film and 18 dyas using PE, PP and AF. As storage temperature high, the rigidity of mushroom decreased. Rigidity of mushroom packed with AF film was less change compared with the other film. Freshness degree of mushroom(refer to Minamide method) could preserve for 3days using Wrap, 6 days using PE, 9 days using PP and 15days using AF film at 1℃.

하악에 발생한 과잉치의 치험례 : A CASE REPORT

박정아,양규호,,최남기,김선미,장희숙 大韓小兒齒科學會 2005 大韓小兒齒科學會誌 Vol.32 No.4

과잉치는 정상치판(dental lamina)의 과도한 증식이 결과로 발생되어, 가족적 성향을 보이며, 쇄골두개이형성(Cleidocranial dysplasia), Gardner 증후군 등의 여러 질환과 관련되어 나타나기도 한다. 그 빈도는 유치열에서 0.3~0.8%, 영구치열에서 1.0~3.5% 이고, 남성에서 호발되며(2:1), 상악에서 더 많이 발생한다(9:1). 상악에서는 mesiodens라고 불리는 중절치 사이의 위치가 가장 흔한 부위이고, 그 다음은 fourth molar와 측절치 부위이다. 하악에서는 소구치 부위가 가장 흔한 부위이고 전치부위에서는 약 2%로 매우 드물게 발생한다. 과잉치의 만기 잔존은 치간 이개, 인접한 치아의 맹출 장애, 치근 흡수 등을 야기하고 과잉치와 관련되어 함치성 낭종이 발생될 수 있으므로 조기진단과 적절한 치료가 중요하다. 본 두 증례는 비교적 드물게 나타나는 하악에 발생한 과잉치로, 하악 전치부와 소구치부에 발생한 과잉치를 발거하고 교정치료를 시행하여 양호한 결과를 얻었기에 보고하는 바이다. Supernumerary tooth was resulted from excessive proliferation of dental lamina and associated with familial tendency and a congenital syndrome such as Cleidocranial dysostosis or Gardner's syndrome. Incidence reports identify a range of 0.3~0.8% in primary dentition. 1.0~3.5% in permanent dentistion with males being affected twice as frequently as females. maxilla nine times as frequently as mandible. The most common supernumeraty tooth is the mesiodens, which located between the maxillary central incisors, and the next common site is the fourth molar and lateral incisors. Supernumerary teeth are uncommon in the mendible, but premolars are the most common supernumerary teeth and occurrence is very rare in the incisor region of the mandible of possibility of diastema and cruption failure displacement. rotation of the associated permanent teeth, root resorption and dentigerous cyst with presence of the supernumerary teeth. In this two case, one supernumerary tooth located in the mandibular incisor region, the other supernumerary tooth located in premolar region. We could get normal alignment of mandibular dentition by extraction and orthodontic treatment.

혼합치열기 전치부 반대교합 아동에서 Fra¨nkel functional regulator III의 치료효과

박정아,양규호,최남기,김선미 大韓小兒齒科學會 2008 大韓小兒齒科學會誌 Vol.35 No.4

본 연구는 혼합치열기 전치부 반대교합 어린이를 대상으로 FR III가 치아와 골격의 성장에 미치는 효과를 평가하고자 하였다. FR III로 처치한 전치부 반대교합을 지닌 30명의 아동(평균나이 7.9 ± 1.1세 : 평균 치료기간 1.5 ± 0.8년)을 대상으로 치료 전후의 측모 두부방사선 사진을 분석하여 다음과 같은 결과를 얻었다. 1. 상악에 대한 FR III의 골격적인 효과는 상악의 하방이동이며, 전방이동은 대조군과 유의한 차이를 보이지 않았다. 2. 하악에 미치는 FR III의 골격적인 효과는 하악의 후하방이동과 SNB의 감소이다. 3. 치아에 대한 FR III의 효과는하악전치 첨부의 후방이동과수평피개의 증가였다. 이상의 결과로 단기간의 FR III 치료는 상악골의 전방이동 촉진효과는 미미하며 상악골의 하방이동, 하악골의 후하방 회전, 수평피개 증가효과가 있음을 알 수 있었다. The purpose of this study was to evaluate the skeletal and dental effects obtained by the Frankel functional regulator III in growing children with Class III malocclusions. Cephalometric changes in thirty children at the time of mixed dentition malocclusions(initial mean age, 7.9 ± 1.1 years; mean treatment duration. 1.5 ± 0.8 years) were analysed. The results were as follows : 1. The skeletal effects on the maxilla showed a significant downward displacement whereas forward displacement was not significant in comparison with the control group. 2. The skeletal effects on the mandible showed statistically significant backward and downward displacement. 3. The dental effects showed statistically significant backward movement in the mandibular incisor tip and increase of overjet. The results suggested that forward displacement on the maxilla was insufficient and treatment effects were caused mainly by downward displacement of the maxilla, backward and downward rotation of the mandible, and the increase of overjet during short period.

복잡 치아종으로 인한 매복치아의 교정적 견인

박정아,양규호,최남기,김선미 大韓小兒齒科學會 2007 大韓小兒齒科學會誌 Vol.34 No.4

치아종은 치성 종양 중 가장 흔한 형태로 증상이 없는 경우가 대부분이며 종종 영구치의 매복이나 맹출지연을 유발한다. 이는 치아를 구성하는 법랑질,상아질,백악질,치수로 구성되며,형태에 따라 복합 치아종과 복잡 치아종으로 구분 된다. 복합 치아종은 다수의 작고 치아와 유사한 형태를 지니며 상악 전치부에 호발하고,복잡 치아종은 무정형의 치성 조직으로 구성되어 있으며 전체 치아종의 약 25%를 차지하고 하악 구치부에 호발한다. 치아종의 병인은 확실치는 않으나 국소적인 외상,감염,유전적 요인이 관여할 것이라 추측된다. 치료는 보존적인 외과적 적출술이 추천되며 재발은 거의 없다. 다음의 두 증례는 각각 하악 제 l대구치와 하악 측절치의 맹출 지연을 주소로 본원에 내원한 환아들로,매복치 상방의 복잡 치아종을 외과적 적출술을 시행하고 매복치의 외과적 노출 및 교정적 견인을 시행하여 양호한 결과를 보였기에 보고하는 바이다. Odontomas are the common type of odontogenic tumors and generally are asymptomatic and frequently lead to impaction or delayed eruption of permanent teeth. They are composed of enamel, dentin, cementurn and pulp tissue and are divided into compound and complex according to the morphology of the hard tissues, Compound odontomas consist of varying numbers of small toothlike structure and have a predilection for the maxillary anterior regions. Complex odontomas consist of an unorganized mass of odontogenic tissues and comprise approximately 25 percent of all odontomas and have a predilection for the mandibular posterior regions. The etiology of odontomas is uncertain but hypothesized to involve local trauma, infection and genetic factors. Treatment of odontoma is conservative surgical removal and are little probability of recurrence. These two cases were about the patients with delayed eruption of mandibular first molar and mandibular lateral incisor. We surgically removed odontoma, exposed impacted tooth and guided impacted tooth into normal position by orthodontic traction. At the completion of traction, the mandibular first molar and mandibular lateral incisor was positioned fairly within the arch and complications such as root resorption were not observed.

학점은행제 표준교육과정의 재구조화 방향 탐색

김재춘,김재현,전선아 한국교육과정학회 2007 교육과정연구 Vol.25 No.3

The prevalence of HPV infection in the semen among Korean men and the effect of HPV infection on sperm parameters

( Seon Ah Kim ),( So Yoon Kim ),( Yoo Kyung Lee ),( Ki Heon Lee ),( Kyeong A So ),( Mi Kyung Kim ),( Sung Jae Kim ),( Doo Jin Paik ),( Joong Shik Lee ),( Hyo Serk Lee ),( Ju Tae Seo ),( Mi Seon Jeong 대한산부인과학회 2015 대한산부인과학회 학술대회 Vol.101 No.-