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      • SCIESCOPUSKCI등재

        Influence of Carbon Black as a Conductor on Electrode Characteristics for Lithium Secondary Battery

        Se-Rah Yoon,Joong-Kee Lee,Jae-Beck Ju,Byung-Won Cho,Dal-Keun Park 한국탄소학회 2002 Carbon Letters Vol.3 No.1

        The electrochemical behavior of the LiCoO2 electrode, containing carbon black as a conductor, depends upon the nature and characteristics of carbon black. In this study, six different kinds of carbon blacks were employed to investigate the relationship between the properties of carbon blacks and electrochemical characteristics of the electrode. The larger amount of surface oxygen functional groups brought the lower electrical conductivity for the carbon blacks. The electrical conductivity of carbon blacks was closely related to the impurities such as ash and volatile content. The rate capability and cyclability of the electrode were improved with the higher conductivity of carbon blacks used. So, it can be concluded that high conductive carbon black plays an important role as a conductor for high rate of charge-discharge capability and initial efficiency.

      • SCIESCOPUSKCI등재

        Oral Administration of KTNG0345 Prepared from Red Ginseng Extracts Reduces UVB-induced Skin Wrinkle Formation in Hairless Mice

        Lee, Min-Jung,Won, Chong-Hyun,Lee, Se-Rah,Kim, Ji-Sook,Oh, Inn-Gyung,Hwang, Eui-Il,Kim, Na-mi,Kang, Byeong-Choel,Chung, Jin-Ho The Korean Society of Ginseng 2008 Journal of Ginseng Research Vol.32 No.1

        Chronic ultraviolet (UV) exposure is the major cause of photoaging that causes skin wrinkling, roughness, dryness, laxity, and pigmentation. Recently, increasing efforts are being made to understand the relationship between foods and skin health. Ginsenosides are present in ginseng (Ginseng Radix Rubra) extract, and are known to have biomedical properties, such as, anti-oxidant and anti-inflammatory effects. In this study, we investigated whether KTNG0345 prepared from red ginseng extracts delivered orally reduces skin wrinkling and ultraviolet B (UVB)-induced wrinkle formation in hairless mouse skin. KTNG0345 was administrated orally to the mice (5 times a week) during the period of UVB-irradiation (3 times a week) for 8 weeks at three different doses of 300 mg/kg, 500 mg/kg and 1000 mg/kg (w/v). UV doses were increased weekly by 1 MED (1MED = 75 $mJ/cm^2)$ up to 4 MED and then maintained at this level. After the 8-week administration period, it was found that orally administered KTNG0345 significantly inhibited UVB-induced wrinkle formation in a dose-dependent manner. Increases in skin thickness caused by UVB were prevented by KTNG0345. Moreover, it also significantly inhibited matrix metalloproteinases (MMP) -13 and MMP-9 expressional inductions by UVB. In addition, KTNG0345 was observed to prevent UVB-induced water loss of epidermis in hairless mouse skin. Our results demonstrate that orally administered KTNG0345 has anti-wrinkling effects in hairless mouse skin, and suggest that dietary red ginseng and herbal mixture may be considered a functional beauty food for preventing UVB-induced skin wrinkles.

      • KCI등재

        정신분열병 환자에 대한 통합심리치료의 효과

        이만홍,이희상,조현상,현명호,안석균,유상우,박지환,한승진,현용호,구민성,손석한,김세주,이현주,박소라,송선미,안혜리,최정아,남궁기,유계준 大韓神經精神醫學會 1998 신경정신의학 Vol.37 No.6

        목 적: 본 연구는 인지재활이 강화된 통합심리치료를 정 신분열병 환자에게 시행하여 그 결과를 평가하고 행상의 문제점을 분석하여 정신분열병 환자의 재활을 위한 한국형 통합심치료를 개발하기 위한 목적으로 실시되었다 . 방 법. 정신분열병으로 입원한 환자에게 인지분화,사회지각, 언어소통,사회기술, 문제해결기술의 5단계 구성된 통합심리치료를 12주간 주3회 실시하였고 치료 전후에 저자들이 개발한 인지분화평가척도, 사회기술평가척로,문제해결기술척도와Positive And Negative Syndrome Scale로 치료효과를 평가하였다. 집단내의 상호작용과 사회적 관심과 같은 비특이적인 간섭변인을 배제하기 위하여 정신건강교육에 의한 관심 -위약 대조군을 설정하여 비교하였다. 결 과: 통합심리치료를 시행한 군은 대조군에 비해 일반정신병리점수와 임상중상 총점수의 유의미한 호전이 있었고 인지기능의 호전은 인지분화 소프로그램후에서만 관찰되었으며 사회기술 소프로그램후의 사회기술기능은 제한적 효과만 있었다. 그러나 통합심리치료 시행군내에서는 12주후 양성증상. 음성증상. 일반 정신병리 모두에서 호전되었다. 결 론: 본 결과는 통할심리치료가 정신분열병 환자에게 임상 중상 영역의 치료효과가 있음을 지지하지만 인지 영역 훈련이 갖는 특정 효과는 보여주지 않았다 한편으로는 치료 프로그램의 사회문화적이고도 언어적인 배경의 차이. 치료기간, 집단구성원의 기능 동질화, 정서 처리, 인지영역 훈련에 대한 치료자의 숙련도 등의 시행상의 문제가 있어 우리나라 환자에의 적용을 위해서는 통합심리치료 원저의 수정이 요구된다. 0bjectives : This study, as a preliminary one attempting to develop the Korean version of Integrated Therapy for the rehabilitation of schizophrenic patients, was designed to investigate the results of Integrated Psychological Therapy(IPT) and review the problems during the program application. Methods : Cognitive Differentiation Scale, problem-Solving Scale, and PANSS(Positive And Negative Syndrome ScalE) were administered to schizophrenic inpatients before and after IPT incorporating cognitive diffirentiation, social perception, verbal communication, social skill and interpersonal Problem-solving skill subprograms. The therapy groups were offered activities three times per week during the 12-week program. The control groups were attention-placebo groups for control ling factors such as group interaction and social attention, and were offered psychoeducation. Results : The 12-week IPT groups, compared with the control groups, demonstrated sign-nificant improvements in the general psychopathology and the total symptoms of PANSS, but did not in cognitive functions and problem-solving skill. Significant improvements in cognitive functions were found only artier cognitive differentiation subprogram and social skill subprogram had limited effects on social skills. But within 12-week IPT groups significant improvements in the positive symptoms, negative symptoms and general psychopathology werc found. Conclusion : These findings support some effectiveness of IPT, but do not address the unique contribution by cognitive components. Applied to schizophrenic patients in this country, this modality had the problems such as differences in sociocultural and lingual background, duration of treatment, homogeneity in the level of the functioning among group members, management of emotions in activities, and the therapists'skill in the training of cognitive components. So the modification of this modality will be required.

      • SCIESCOPUSKCI등재

        Influence of Carbon Black as a Conductor on Electrode Characteristics for Lithium Secondary Battery

        Yoon, Se-Rah,Lee, Joong-Kee,Ju, Jae-Beck,Cho, Byung-Won,Park, Dal-Keun 한국탄소학회 2002 Carbon Letters Vol.3 No.1

        The electrochemical behavior of the $LiCoO_2$ electrode, containing carbon black as a conductor, depends upon the nature and characteristics of carbon black. In this study, six different kinds of carbon blacks were employed to investigate the relationship between the properties of carbon blacks and electrochemical characteristics of the electrode. The larger amount of surface oxygen functional groups brought the lower electrical conductivity for the carbon blacks. The electrical conductivity of carbon blacks was closely related to the impurities such as ash and volatile content. The rate capability and cyclability of the electrode were improved with the higher conductivity of carbon blacks used. So, it can be concluded that high conductive carbon black plays an important role as a conductor for high rate of charge-discharge capability and initial efficiency.

      • KCI등재

        Oral Administration of KTNG0345 Prepared from Red Ginseng Extracts Reduces UVB-induced Skin Wrinkle Formation in Hairless Mice

        Min Jung Lee,Chong Hyun Won,Se Rah Lee,Ji Sook Kim,Inn Gyung Oh,Euiil Hwang,Nami Kim,Byeong Choel Kang,Jin Ho Chung 고려인삼학회 2008 Journal of Ginseng Research Vol.32 No.1

        Chronic ultraviolet (UV) exposure is the major cause of photoaging that causes skin wrinkling, roughness, dryness, laxity, and pigmentation. Recently, increasing efforts are being made to understand the relationship between foods and skin health. Ginsenosides are present in ginseng (Ginseng Radix Rubra) extract, and are known to have biomedical properties, such as, anti-oxidant and anti-inflammatory effects. In this study, we investigated whether KTNG0345 prepared from red ginseng extracts delivered orally reduces skin wrinkling and ultraviolet B (UVB)-induced wrinkle formation in hairless mouse skin. KTNG0345 was administrated orally to the mice (5 times a week) during the period of UVB-irradiation (3 times a week) for 8 weeks at three different doses of 300 ㎎/㎏, 500 ㎎/㎏ and 1000 ㎎/㎏ (w/v). UV doses were increased weekly by 1 MED (1MED = 75 mJ/㎠) up to 4 MED and then maintained at this level. After the 8-week administration period, it was found that orally administered KTNG0345 significantly inhibited UVB-induced wrinkle formation in a dose-dependent manner. Increases in skin thickness caused by UVB were prevented by KTNG0345. Moreover, it also significantly inhibited matrix metalloproteinases (MMP) -13 and MMP-9 expressional inductions by UVB. In addition, KTNG0345 was observed to prevent UVB-induced water loss of epidermis in hairless mouse skin. Our results demonstrate that orally administered KTNG0345 has anti-wrinkling effects in hairless mouse skin, and suggest that dietary red ginseng and herbal mixture may be considered a functional beauty food for preventing UVB-induced skin wrinkles.

      • KCI등재

        Placental Site Trophoblastic Tumor의 임상병리학적 특징에 관한 연구

        김승조,이헌영,정재근,남궁성은,나덕진,정기욱,신희정,이원희 대한산부인과학회 1994 Obstetrics & Gynecology Science Vol.37 No.3

        저자들은 1986년 1월부터 1991년 12월까지 가톨릭 의과대학 산부인과학교실에서 진단 및 치료를 받은 PSTT환자 4명을 대상으로 임상병리학적 연구를 시행하여 다음과 같은 결과를 얻었다. 1. 환자의 평균연령은 28세이고 평균분만력은 0.75회였다. 2. 마지막 임신력과의 관게에 있어서 만삭임신이 2예(50%), 포상기태 1예(25%) 그리고 조산, 임신중독증 및 선천성기형 동반임신 1예(25%)였었다. 3. 종양기간에 있어서는 10-28개월로 평균 16.8개월이었다. 4. 임상증세로는 3예(75%)에서 소량의 질출혈을 호소하였고 1예(25%)에서는 무월경만을 호소하였다. 5. 종양표지물질과의 관계에서 b-hCG는 3예에서 초기에 21-858 mIU/ml을 나타내었으며 1에에서만 13,480 mIU/ml의 상대적으로 높은 수치를 나타내었다. hPL은 1예에서만 조사한 결과 0.1 mg/l이하의 결과가 나왔다. 6. 초기진단방법에 있어서는 전에에서 자궁내막검사로 진단을 내렸으며 세포분열양상은 10고배율상 1-4개를 나타내었으며 전이소견은 없었다. 7. 치료는 2예(50%)에서 수술 및 화학요법으로, 나머지 2예(50%)에서는 화학요법만으로 완전관해를 이루었으며 그중 각 1예씩에서 후에 정상임신이 되었었다. 이와같이 드물고 치료에 잘 반응하지않는 PSTT인 경우에도 초기 병리학적검사로 다른 임신성융모성질환과 감별할 수 있으며 수술적 요법 및 적절한 화학요법으로 좋은 결과를 얻을 수 있었다. 그러나 좀더 정확히 알기위해서는 더 많은 예에서 연구가 이루어져야 할 것으로 생각된다. Placental site trophoblastic tumor (PSTT) is a rare from of gestational trophoblastic disease and the patients with a placental site trophoblastic tumor clearly present a wide rage of clinical courses. Because of its apparent benign nature, it was originally termed trophoblastic pseudotumor of the uterus. The name was later changed when cases were reported of metastatic tumors resistant to chemotherapy leading to he death of the patients. We have studied clinicopathological study on placental site trophoblastic tumor correlation of PSTT in 4patients from January 1986 to December 1991 at Department of Obstetrics and Gynecology, Catholic University Medical College, and the results were as follows: 1. The mean age of PSTT was 28 years old and mean parity was 0.75. 2. The antecedent pregnnacy ended in term pregnancy in two patients, H-mole in one patiend and premature, preeclampsia with congenital anomaly in one patient. 3. The interval from the antecedent pregnancy to diagnosis of PSTT ranged from 10 to 28 (mean 16.8) months. 4. Presenting symptom was vaginal spotting in 3 patients and secondary amenorrhea in one patient. 5. Pretreatment hCG levels obtained in 3 patients ranged 28-858 mIU/ml but one patient have a high value as 13,480 mIU/ml. The pretreatment hPL levels obtained in 1 patients was a 0.1 mg/ml. 6. All four were diagnosed as having a PSTT by endometrial curretage and all were initially determined to have nonmetastatic lesion. 7. Two patients were treated by total abdominal hysterectomy and adjuvant chemotherapy and two patients were treated with chemotherapy only. All four have remaiend in clinical and gonadotropin remission and two of them have outcome of normal pregnancy.

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