Time-Related Changes in Detrusor Overactivity in Awake Rats with Spinal Cord Injury Observed by Simultaneous Registrations of Intravesical and Intraabdominal Pressures

Jin, Long-Hu,Shin, Hwa-Yoan,Yoon, Seung-Hwan,Seong, Do-Hwan,Park, Chang-Shin,Lee, Tack,Yoon, Sang-Min Korean Continence Society 2011 International Neurourology Journal Vol.15 No.1

<P><B>Purpose</B></P><P>To compare the physical characteristics of detrusor overactivity (DO) induced by intravesical infusion of saline in awake, sham rats and rats with chronic spinal cord injury (SCI), by simultaneous registrations of intravesical and intraabdominal pressures.</P><P><B>Methods</B></P><P>Male Sprague-Dawley rats, normal or with a spinal vascular clip at the level of Th9, were investigated cystometrically 1 and 4 weeks after SCI. Intravesical pressure (IVP) and intraabdominal pressure (IAP) were recorded simultaneously to evaluate true DO. During the filling phase, the event of IVP rises, defined as increments that exceeded 2 cmH<SUB>2</SUB>O from baseline, were determined as DO according to the absence of simultaneous changes in IAP.</P><P><B>Results</B></P><P>All SCI rats exhibited DO during the filling phase, which was not shown in sham rats. The frequency and pressure of DO had a tendency to decrease with time. The DO frequency of SCI rats after 4 weeks (0.9±0.2 min<SUP>-1</SUP>) was decreased compared with that after 1 week (2.1±0.4 min<SUP>-1</SUP>; P<0.05). The DO pressure of SCI rats after 4 weeks (8.4±1.9 cmH<SUB>2</SUB>O) was decreased compared with that after 1 week (11.6±2.9 cmH<SUB>2</SUB>O; P>0.05).</P><P><B>Conclusions</B></P><P>Cystometric studies in awake male SCI rats showed some significant changes in bladder function after SCI. All SCI rats exhibited DO during the filling phase, and showed different physical characteristics of DO over the course of time. The neurological basis of these time-related changes remains poorly understood, but may provide important prognostic information about long-term urological management in SCI patients.</P>

DO와 ORP를 이용한 축산폐수처리 SBR운전 제어

전병희 ( Byong Hee Jun ),김도환 ( Do Hwan Kim ),최은희 ( Eun Hee Choi ),김성신 ( Sung Shin Kim ),김창원 ( Chang Won Kim ),배현 ( Hyeon Bae ) 한국물환경학회 2002 한국물환경학회지 Vol.18 No.5

A pilot scale SBR (working volume, 20㎥) treating piggery wastewater was operated with real wastewater. The operation mode of intermittent feeding of raw water and sub-cycle with repeating anoxic-aeration conditions were adapted to avoid the high-strength nitrogen inhibition. In sub-cycle, aeration time for nitrification was tried to be controled with ORP and/or DO meter. The characteristics of control was somewhat different between ORP and DO. DO showed potential ability to detect complete ammonia oxidation point by the first order differential values or absolute value. Especially, DO was proved to be useful for high loading rates. ORP indicated the ending point of nitrification by the plateau appearing after bending point. Because ORP can be utilized as a diagnosis tool by its good sensitivity for the microbial condition in reactor, the simultaneous application of DO and ORP was recommended for the stable control of SBR.

광범위하게 진행된 다발성 섬유성이형성증

이병도,황의환,이상래 대한구강악안면방사선학회 2000 Imaging Science in Dentistry Vol.30 No.2

Fibrous dysplasia is a benign disorder of bone consisting of intramedullary proliferation of fibrous tissue and irregularly distributed, poorly developed bone. The disease manifests itself in the monostotic form in which only one bone is involved and the polyostotic form in which multiple bones at different sites are affected. We reported a extensive case of polyostotic fibrous dysplasia with involvement of craniofacial bones, mandible, ribs and extremities. A 18-year-old man showed remarkable right facial swelling who had been treated on right femur 3 years ago with a bone graft for pathologic fracture and he recognized facial swelling 5 years ago. Extraoral radiograms and computed tomogram showed diffuse sclerosis with a ground glass appearance of the most cranial bones, facial bones, The right mandibular lesion showed very expansive lesion with mottled appearance. Bone scans showed mutifocal increased uptakes in craniofacial bones, right mandible, bilaterally in ribs, humerus, femur, tibia and characteristic varus deformity of right femur (shepherd's crook defomity). This case showed exceptionally bilateral, extensive nature of bone lesion and didn't show any features of skin pigmentation and endocrine disturbances.(Korean J Oral maxillofac Radiol 2000 ; 30 : 117-122)

버들치(Rhynchocypris oxycephalus)의 vitellogenin 생성량 측정을 이용한 수중 estrogen휴 화합물의 정량분석법에 관한 연구

김을환,이도부,한상훈,윤병수 경기대학교 부설 기초과학연구소 2005 경기대학교 기초과학논문집 Vol.18 No.1

Vitellogenin(Vtg), a phospholipoglycoprotein precursor of egg yolk, is synthesized and secreted from the liver in response to estrogens in female fish. Vtg is normally undetectable in the blood of male fish, but can be induced by exposure to chemicals possessing estrogenic activity. Thus, the presence of Vtg in blood of male fish can serve as a useful biomarker for assessing previous exposure to estrogenic compounds. In the present study, Vtg was abnormally expressed in Rhynchocypris oxycephalus treatment of Estradiol Benzoate (E_(2)). As the result, it was found that the level of Vtg in blood from R. oxycephalus was increased by treated quantity of E_(2) with dose-effect manner.

만성 호중구성 백혈병 1례

기장도,박치영,류보열,김태종,모성환,곽재정,문철호,박근홍,박유환,정춘해 朝鮮大學校 附設 醫學硏究所 1996 The Medical Journal of Chosun University Vol.21 No.1

Chronic neutrophilic leukemia is a very rare myeloproliferative disorder which is characterized by severe sustained mature neutrophilic leukocytosis in peripheral blood (PB), hepatosplenomegaly, elevated leukocyte alkaline phosphatase, serum uric acid. serun viatmin B 12 and the bleeding tendency despite normal platelet count and coagulation time, absence of philadelphia chromosome, and the absence of fever or underlying infection or disease sufficient to mimic a leukemoid reaction. We have experienced a 34-years-old male patient with atypical chronic neutrophilic leukemia. On admission, the leukocyte count was 56,860/uL. severe neutrophic leukocytosis with 76% neutrophils and rare immature forms on PB smear. Many neutrophils had toxic granules, and vacuoloes. Leukocyte alkaline phosphatase score was decreased. The cytogenetic study showed Philadelphia chromosome negative with normal karyotype.

교량의 실측 가속도 자료의 적분을 통한 변위 응답 추정에 대한 연구

정진환,김영찬,김성도,계만수 釜山大學校生産技術硏究所 1998 生産技術硏究所論文集 Vol.55 No.-

구조물의 동적 거동을 측정하고 측정된 자료에 대한 분석을 통하여 구조물의 안전과 내구성을 판단하는 것이 매우 중요하다. 이러한 목적에서 수행되는 구조물의 거동계측에서 구조물의 가속도응답의 측정은 변위응답의 측정보다 훨씬 용이하고 경제적이지만 변위응답의 물리적 의미는 가속도응답보다 명백하다. 본 연구에서는 변위응답의 측정보다 훨씬 용이하고 경제적인 가속도 응답을 계측하고 가속도 데이터를 적분하여 변위응답을 추정해 내는 알고리즘을 개발하여, 실내 실험을 통하여 계산된 변위와 측정된 변위응답을 비교하여 이를 검증하고, 실제 교량의 측정자료에도 적용해 보았다. It is important to measure the dynamic behavior of the structures and also to assess the safety and serviceability of those structures by the gathered data. It is much easier and more economical to measure the accelerations than displacement sin order to obtain the dynamic responses of a structure, but the physical meanings of the displacements are more clear and definite than those of accelerations. In this study, the algorithm which can evaluate the displacements from the measured acceleration data by integration is developed. The calculated displacements are compared with measured data through the laboratory test and the results represent good agreements. This algorithm is applied to the data of real structures.

형질변형성장인자가 손상골 재생능에 미치는 영향에 관한 실험적 연구

황의환,이상래,홍정표,이병도 大韓口腔顎顔面 放射線學會 1995 Imaging Science in Dentistry Vol.25 No.2

The purpose of this study was to observe the effect of TGF-β1, which promotes differentiation and proliferation of osteoblasts, on bone regeneration. Experimental bone defects that measured 3 mm in diameter were created on the mandibles of guinea pig by removal of bone with the use of trephine burns. In one side of mandibular body the experimental groups, bone defects were grafted with Biogran(Orthovita Co., U.S.A.) and TGF-β1(R&D System Co., U.S.A.). IN the remaining side of the mandiblar body, the control groups, bone defects were grafted with only Biogran. Guinea pigs in the control and experimental groups were serially terminated by fours on the 3 days, the 1 week, the 2 weeks, the 3 weeks, and the 4 weeks after experiment, and both sides of the mandibular bodies were removed and fixed with 10% neutral formalin. They were decalcified and embedded in paraffin as using the usual method. The specimen sectioned and stained with hematoxylin and eosin. Also, they were radiographed with a soft X-ray apparatus The obtained results were as follows; 1. Hemorrhagic condition, observed in the granulation tissues, disappeared on the 1 week after experiment in both groups, and more prominent in the experimental group. The granulation tissues of the experimental group had larger number of cells than those of the control group. 2. Osteoblastic differentiation in the margin of grafted material and adjacent bone was observed on the 1 week after experimental in both groups. Also, bone formation was observed in immature form on the 1 week after experiment, and more prominent in the experimental group. 3. In the polarizing microscopic examination, bone matrix was very loose on the 1 week after experiment, but increase in density with time, and more prominent in the experimental group. 4. In the microradiographic examination, newly formed bone was observed in the experimental group on the 2 weeks after experiment, and this was observed earlier than in the control group. Newly formed bone was increased with time and defected area was markedly decreased on the 4 weeks after experiment.

煖房 放熱器의 熱傳達 特性에 關한 硏究

鄭性煥,兪昌道,金善政 大田産業大學校 2000 한밭대학교 논문집 Vol.17 No.1

A study has been conducted experimentally on natural convection heat transfer characteristics of a heating flat plate with heat diffusion fins in air. The effects of heat diffusion fin lengths, heating plate temperature, air velocity, and Rayleigh numbers are mainly investigated. The mean heat transfer coefficient decreases as a dimensionless fin length increases and heating place temperature 60℃ is the best at constant heat flux. The mean Nusselt number increases with increasing Rayleigh number and Reynolds number and H/S = 1.0 in the dimensionless fin length is found to be the optimun size in a tested length, 1.0≤H/S≤4.0

태양광 발전효율 향상을 위한 태양 추적 제어에 관한 연구

송도성,임종환 제주대학교 공과대학 첨단기술연구소 2006 尖端技術硏究所論文集 Vol.17 No.1

The photovoltaic(PV) power generation system transforms unlimited and pollution-free solar energy directly into electronic energy by using solar cells of semi-conductor devices. The PV power is globally attractive renewable energy in relation to problem of environmental pollution, and will be an important future energy sources. In this study the solar tracking system have been developed that can trace the direction of sun to keep the PV array perpendicular to the sun lay. The system is able to localize by itself using GPS, and it do not need a brake system. It uses very low power DC motors, so that it does not need external power. Furthermore, it has an ability to judge whether it is possible to generate or not depending on the light intensity. Also it can maintain the PV array horizontally to prevent from demage when the wind is strong.

국제화를 위한 부산대학교 재학생들의 영어 구사력

이상도,안동환,김성애 釜山大學校 1997 人文論叢 Vol.50 No.1