뇌수막종에 대한 고식적 방사선 치료 : 7예 치험보고 Experience of 7 Cases

이창훈,윤상민,이승훈,김종현 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.12

Meningiomas had long been considered radioresistant and therefore the role of radiation therapy in its treatment remains controversial. Lately, however, most of the retrospective analysis of meningiomas indicates that radiation therapy does show some degree of beneficial effects not only for malignant but also for benign meningiomas with the advanced technology and increased amount of radiation therapy, the rate of growth of tumor had been successfully slowed and local recurrence rate is also reduced following subtotal resection. We have performed conventional high dose radiation therapy on 7 cases of meningiomas (four cases of meningotheliomatous meningiomas, and three cases of malignant meningiomas). Of the 7 cases, the residual mass of 6 had decreased in size and neurological improvement was also evident. However, the 7th case resulted in complicated hydrocephalus. These cases are presented and the effect of conventional radiation therapy is discussed together with the review of literatures.

지역경제 활성화를 위한 테크노파크의 역할에 관한 연구 : 경북 테크노파크를 사례로 Focused on the Case of Kyongbuk Technopark

이재훈,김상곤 영남대학교 지역발전연구소 2001 영남지역발전연구 Vol.28 No.-

In the preparation for the 21st century's knowledge-based society, our government has set up various policies to foster the competitivaness of regional economies, one of which is starting the 6 "model technopark" projects. The rationale for theses policies is region-oriented. The purpose of this study is to analyze the effects of Kyongbuk Technopark on the Kyongsan City's economy. Under this purpose, we took as a case Kyongbuk Technopark(KTP), which is regarded as having locational advantages. In this case study, we analyzed KTP's locational environments and performance and suggested the desirable roles of KTP based on the analyses. Technopark's generally accepted definition is sets of lands, buildings, and facilities, where universities, research institutes, municipal governments and industries get together and provide theses following function: (1) R&D; (2) facilities and equipments; (3) technology business incubation; (4) technology innovation centers; (5) pilot plants; (6) distribution of information; (7) management services; (8) career, educational, or entrepreneurial opportunities for local businessmen, students, and inhabitants, and etc. Analyses indicated that KTP has performed those above functions very well so far and thus acquired good reputation and visibility for itself. For examples, it has contributed many hob creations through new startups, and thus played in important role of fostering Kyongsan City's economic competitiveness. Based on these results, we suggested KTP's future roles as follows; firstly, KTP should serve as fostering Kyongsan's competitiveness by being focused on the region specific industries. More specifically, KTP should continue to create jobs through business incubation focusing on textile and machinery industries and serve to restructure the regional industries from low value added to high value added secondly, it should construct regional technology infrastructure. In addition, it should lead regional information system, construct intra-and inter-technology innovation networking through distribution of functions between institutions and finally serve as a hub of regional innovation system; and it should participate in the regional policy-making and provide the cultural and rest area for local citizens.

부산의 도시브랜드 개성에 대한 연구

이상훈, 최일도 신라대학교 부산학연구센터 2006 부산연구 Vol.10 No.-

The purpose of this study is to establish the personality factor of citizen for Busan city-brand of communication effects. So this study intended to show the influence and process of brand personality factor between brand attitude formation on Busan city-brand PR campaign. Therefore, survey go side by side will conducted for the university students in Busan. For the research sample was consists of 234 persons. The results showed that Busan city-brand personality were distributed 5-factor like ‘ability’, ‘tradition’, ‘humor’, ‘polish’, ‘kindness’ and so on. This result indicated that utilizing various communication mix or divide is more available to differentiate city-brand. Moreover, this study met with significant results when maintained the consistency of city-brand PR campaign strategy between personality factor and attitude formation process. So this study may give useful guide for communicators to city-brand PR campaign strategy using various communication tools about appeal range and message construct in brand perspective. 본 연구는 도시브랜드로서의 부산이 지니고 있는 브랜드 개성을 조사해 커뮤니케이션 영향요인을 도출함으로써 효율적인 도시브랜드화 과정에 필요한 커뮤니케이션방안을 모색하려는 목적에 따라 진행됐다. 브랜드 개성은 공중과의 커뮤니케이션 효과를 논의할 수 있는 요인이자 도시브랜드화에 핵심적인 부분이므로 다양한 개성의 차원과 영향요인을 파악할 수 있다. 조사대상 공중으로서의 표본은 조사대상물로 선정한 부산에 거주하고 있는 대학생 계층으로 구성했다. 표본의 크기는 전체 234명이었다. 연구의 결과 표본에게 제시한 도시브랜드로서의 부산이 지니는 브랜드 개성은 크게 ‘능력’, ‘전통’, ‘유머’, ‘세련’, ‘친절’ 등의 5가지 요인으로 크게 분류할 수 있었다. 이 같은 결과는 현재 부산에 대한 도시브랜드 PR 캠페인을 전개하는 과정에 표현영역과 의미구성 영역에 고려해야 할 개성요인이 무엇인가를 제시해주고 있다.

재발한 희돌기 교세포종에 대한 BCNU-CDDP 연속정주 화학요법

윤상민,이창훈,이승훈,송재욱,김종현 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

Eight patients with recurrent oligodendroglioma were treated with 1.3-bis(2-chloroethyl) nitrosourea(BCNU) and CDDP continuous infusion chemotherapy. They were 5 with benign oligodendrogliomas and 3 with anaplastic oligodendrogliomas. All the recurrent tumors had been treated with surgery and radiotherapy. Four patients had already received chemotherapy with ACNU. Seven of them showed response to continuous infusion chemotherapy. The time from the response to progression was 15 to 67 weeks. No severe complication of the chemotherapy was found. In conclusion, BCNU-CDDP continuous infusion chemotherapy is an effective treatment modality in recurrent oligodendrogliomas.

척수로 전이된 후두엽 다형성 교아세포종 : 증례보고 A Case Report

윤상민,송재욱,이창훈,조경자,김종현,이승훈 대한신경외과학회 1996 Journal of Korean neurosurgical society Vol.25 No.3

The tendency of glioblastoma to metastasize to the cerebrospinal fluid(CSF) is well documented, reaching approximately 20% in autopsy series. Nevertheless, clinical symptoms from spinal seeding seem to be infrequent or are at least rarely diagnosed. The authors report a case of 41-year old female patient with a cerebral glioblastoma multiform who developed paraplegia due to a pathologically confirmed spinal matastasis.

난치성 양극성 장애의 약물치료 : 새로운 항경련제와 칼슘통로 차단제

김영훈,이정구,이상경 대한생물치료정신의학회 1998 생물치료정신의학 Vol.4 No.1

Most psychiatrists are familiar with the traditional anticonvulsants, carbamazepine and valproic acid, in the treatment of the patients with bipolar disorders. Lamotrigine, a new anticonvulsant, may have antidepressant and mood-stabilizing effects probably by inhibition of pathological glutamate release on the presynaptic membrane, especially in the treatment-refractory bipolar disorders. Treating depression in bipolar disorder can be difficult because of the limited antidepressant effects of the standard mood stabilizers and the tendency of antideressants to induce mania or decrease cycle length. Lamotrigine, a drug that has both mood stabilizing and antidepresasant effects, woud have an important role in the treatment of refractory bipolar disorders. The efficacy of verapamil in the treatment of mania has been examined in several small open trials and at least 7 double-blind trials, and that of nimodipine in a double-blind trial. Although preliminary data suggest that verapamil may have antimanic or mood-stabilizing properties, any conclusion about the efficacy of verapamil in the treatment of the lithiun-refractory or rapid cycling bipolar patients could not be drawn till now.

DP매칭에 의한 On-Line 악보인식

구상훈,이은주 한밭대학교 정보통신전문대학원 2003 정보통신전문대학원 논문집 Vol.1 No.1

실시간으로 악보를 인식하고,사용자의 편의를 도모하기 위해 DP(Dynamic Programming) 매칭법을 이용 한 On-Line 악보인식에 관한 방법을 제안하였다. 본 연구에서는 실시간으로 입력되는 악상기호를 인식하기 위해, 가장 유효한 정보인 악상 기호내의 x, y 좌표를 이용하여 16방향 부호화를 수행하여 입력패턴을 생성한 다음 표준패턴과의 DP매칭을 통하여 벌점을 구한다. 그리고 경로탐색을 통해 벌점에 대한 각각의 합계를 구해 최소값을 악상기호로 인식 하였다. 실험결과,표준패턴을 음표와 비음표의 두개의 그룹으로 나누어 인식함으로써 DP매칭의 처리 속도를 개선시켰고,국소적인 변형이 있는 패턴과 특징의 수가 다른 패턴의 경우에도 좋은 인식률을 얻었다. We proposed method about On-Line sheet music recognition by using Dynamic Programming matching method to recognize sheet music by real time, and maintain user's convenience. In this paper, we yield penalty through DP matching with standard pattern after run 16 directions encoding and create input pattern using x, y coordinate in theme symbol that is the valid information to recognize theme sign that is inputed by real time. And we recognized theme symbol by smallest value of each total about penalty through path search. In experiment result, we improved the processing speed of DP matching by recognizing dividing standard pattern to two group as note and non-note, and received the fine recognition rate in case of pattern with local transform and pattern that number of characteristic is different.

지방광고주의 광고회사 선정 및 평가에 관한 실증 연구

하봉준,이상훈 한국방송광고공사 2004 광고연구 Vol.0 No.63

낙후된 지방 광고산업의 발전을 위해서는 구조적 요인의 해결과 함께, 광고산업 주체의 자구노력이 병행되어야 한다. 특히 지방광고회사의 발전을 위해서는 지방광고주의 지방광고회사에 대한 인식 및 만족도 제고가 선결과제라고 할 수 있다. 본 연구는 이러한 문제의식하에서 지방광고주가 광고회사를 선정하는 기준은 무엇인지, 그리고 지방광고회사를 어떻게 평가하고, 개선점은 무엇이라고 생각하는지 실증적으로 알아보고자 하였다. 부산/울산/경남 지역의 광고주 및 광고회사 종사자를 대상으로 설문조사를 실시한 결과, 지방광고주는 광고회사 선택시 거래요인을 중요하게 고려하고, 거래요인 및 비용측면에서 지방광고회사를 높이 평가했다. 그러나 지방광고회사는 광고기획/전략, 마케팅, 리서치, 광고회사의 규모/크기 등 업무 측면이나 외형적 특성에서 낮게 평가되었고, 향후 업무요인에 대한 개선이 요구되는 것으로 나타났다. 이상의 연구결과를 고려할 때, 지방광고회사는 우선적으로 광고기획/전략, 마케팅, IMC, 리서치, 크리에이티브 등 광고 업무와 관련된 서비스의 질을 높이는 데 노력해야 하며, 동시에 기존의 강점 중에서 장기적인 경쟁적 우위가 될 수 있는 지역특성에 대한 이해, 광고주 요구에 대한 정확하고 신속한 반응 등에 대한 강화가 요구된다. The purpose of this study is to make empirical investigation into advertising agency selection and evaluation of the local client for the local agency’s developing plan. The following research questions were formulated for this study. 1. What are mainly considered factors when the local client selects a agency? 2. How is the local agency evaluated in comparison with the agency that is located in Seoul? 3. What should be improved for the development of the local agency? To get the proper answers, a total of 172 persons who have been employed in local agencies and clients located in Busan, Ulsan and Gyeongnam-do are surveyed for this study. T-test, factor analysis and regression analysis were chosen as the appropriate statistical techniques. The main results are: 1. The local client considers transaction and cost more importantly when they selects a agency. 2. The local client estimates that local agency is better than the agency in Seoul about transaction and cost. 3. The local client wants the local agency to improve its own abilities - advertising planning, marketing consulting, IMC, research and creative power.

국소교란에 의한 난류박리 재부착 유동의 수치해석

리광훈,성형진,Rhee, Gwang-Hoon,Sung, Hyung-Jin 대한기계학회 2000 大韓機械學會論文集B Vol.24 No.3

An unsteady numerical simulation was performed for locally-forced separated and reattaching flow over a backward-facing step. The local forcing was given to the separated and reattaching flow by means of a sinusoidally oscillating jet from a separation line. A version of the $k-{\varepsilon}-f_{\mu}$ model was employed, in which the near-wall behavior without reference to distance and the nonequilibrium effect in the recirculation region were incorporated. The Reynolds number based on the step height (H) was fixed at $Re_H=33000$, and the forcing frequency was varied in the range $0{\leq}St_H{\leq}2$. The predicted results were compared and validated with the experimental data of Chun and Sung. It was shown that the unsteady locally-forced separated and reattaching flows are predicted reasonably well with the $k-{\varepsilon}-f_{\mu}$ model. To characterize the large-scale vortex evolution due to the local forcing, numerical flow visualizations were carried out.

실험적 백서 9L Gliosarcoma 뇌종양 모델 개발

김종현,이승훈,이창훈,윤상민 대한신경외과학회 1995 Journal of Korean neurosurgical society Vol.24 No.5

Experimental brain tumor model is essential for the development of new therapeutic modalities of brain tumors and evaluation of efficacy of each therapeutic variety. Authors developed experimental rat brain tumor model with 9L and C6 cell line in Fisher rat using stereotactic method. We tried to determine the tumor occurrence rate, the ideal time for secondary experiment using this brain tumor model. and the duration between the onset of neurological signs and the time of expiration. We performed autoradiography for each cell line to evaluate the reliance of the tumor model. We could make good tumor model in all the cases of experiment and expect to use it in another extension of experiment.