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      • Thiopental Sodium, Propofol(Diprivan^�) 및 Midazolam이 안압에 미치는 영향

        최정은,서경덕,서동선,최세진 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

        Intraocular pressure(IOP) were measured during induction of anesthesia with thiopental sodium(n = 10), propofol(n=10), and midazolam(n=10). IOP were measured using a Schioetz tonometer before and after induction, and 1min and 3min after endotracheal intubation. All patients were divided into three groups as follows ; Group Ⅰ(n=10) : thiopental sodium 5mg/kg was administered intravenously for induction of anesthesia Group Ⅱ(n=10) : propofol 2mg/kg was administered intravenously for induction of anesthesia Group Ⅲ(n=10) : midazolam 0.2mg/kg was administered intravenously for induction of anesthesia Succinylcholine 1mg/kg were administered intravenously for endotracheal intubation in all groups. The results were as follows ; 1) Induction of anesthesia with propofol and thiopental sodium are associated with a significant reduction in IOP. 2) Induction of anesthesia with propofol is associated with more significant reduction in IOP than thiopental sodium. 3) Induction of anesthesia with midazolam is not associated with reduction in IOP. From above results, propofol can be used as effectively as thiopental sodium for general anesthesia in patients who undergo ophthalmic surgery.

      • Propofol이 정맥 마취 유도 및 유지시 심혈관계에 미치는 영향

        최세진,박세린,조희경,김만수,임정혁 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.2

        The cardiovascular response to anesthesia with the aqueous emulsion formulation of propofol was studied in healthy patient (ASA I or II; aged 20-61 years) premedicated with atropine 0.01mg/kg who underwent superficial minor surgery. Anesthesia was induced in all patient with propofol 2mg/kg - 2.5mg/kg immediately maintained by a continuous intravenous infusion of 6mg/kg/hr to supplement 50% nitrous oxide. We compared the cardiovascular changes of preinduction and post-induction. The results were as follows; 1) Heart Rates remained unchanged but increased in response to laryngoscopy and tracheal intubation from pre-laryngoscopy values and there were no significant changes. 2) Systolic and diastolic arterial pressure were decreased significantly at 1 minute after induction (p<0.01), 5 minutes after intubation (p<0.05), 10 minutes after intubation (p<0.001). Although the arterial pressure increased in response to tracheal intubaton and surgical stimuli, there were no significant changes.

      • 개에서 발생한 기관 허탈의 진단과 관리

        이새미,윤기영,서경원,최호정,정성목,송근호,조종기,박성준 忠南大學校 獸醫科大學 附設 動物醫科學硏究所 2012 動物醫科學硏究誌 Vol.19 No.1

        A 11-year-old Yorkshire terrier anesthetized for computed tomography. The dog showed cyanosis and syncope during postanesthetic recovery, therefore drug administrated parenterally. Goose-honking was noticed after full recovery. As a result of survey radiography and fluoroscopy, grade 4 tracheal collapse was diagnosed. Prescription for the dog was oral administration of hydrocodone 0.22 mg/kg. theophylline 20 mg/kg, prednisone 0.5 mg/kg, amoxicillin 22 mg/kg and chlorpheniramine 2 mg/kg twice a day for 3 days. A 10-year-old Pomeranian was diagnosed as grade 2 traceal collapse at the local animal hospital 2 years before being referred to the veterinary teaching hospital of Chungnam National University. On physical examination, goose-honking, coughing and intermittent open-mouth breathing. Tracheal narrowing was observed on survey einradiography and fluoroscopy. Oral administration of theophylline 13 mg/kg, enrofloxacin 5 mg/kg, chlropheniramine 0.5 mg/kg twice a day was prescribed for 2 weeks.

      • 수술중 수혈환자에 대한 임상적 고찰(Ⅲ)

        최세진,서경덕,조희경 충남대학교 의과대학 지역사회의학연구소 1992 충남의대잡지 Vol.19 No.2

        Over the Past several decades blood and blood components have been increasingly, recognized as medication rather than innocuous fluids used to replace modest blood lose at operation. But blood transfusions have the potential for many harmful side effects. This study was undertaken to evaluate transfusion accordings to department, sex, preoperative hemoglobin values, blood type, transfusion amounts and blood component therapy. Of a total 34.906 operative cases, 5,793 patients who recived a transfusion during operation were analyze statistically at the Department of anesthesiology, chungnam National University Hospital from January 1985 to September 1992. The results were as Follows : 1) The numbers of transfused patient among the 34,906 operative cases were 5,793 cases (16.57%). 2) The number of male transfused was greater than of female and third decade patients was the greatest incidence among the transfused patients. 3) Mostly hemoglobin value in preoperative state was maintained more than 10 mg/dl (85.75%). 4) The blood types of transfused blood were in the great order of A, B, O, AB type. 5) The percentage of one pint transfusion was gradually decreased and 2~5 pints transfusion was greatest percentage (60.11%). 6) As the amount of blood transfused was increased, the percentage of blood component therapy was increased, and mixed case PRC and FFP was the greatest incidence (46.02%).

      • 경막외마취 환자에서 10% Pentastarch 용액의 혈장확장효과

        이정은,박병룡,김은경,김만수,최세진 충남대학교 의과대학 지역사회의학연구소 1993 충남의대잡지 Vol.20 No.1

        In order to compare the effect of 10 % pentastarch solution with Ringer's lactate solution on plasma volume expansion in thirty epidural anesthetic patients, systolic arterial blood pressure (SABP), diastolic arterial blood pressure(DABP), heart rate(HR), central venous pressure(CVP), cardiac output(CO) and changes of hemoglobin(Hb) were measured. The patients were devided into three groups Group Ⅰ (n=10) ; Epidural anesthesia was performed without fluid infusion previously(control) Group Ⅱ (n=10) ; 500 ml of Ringer's lactate solution was rapid infused intravenously before epidural anesthesia Group Ⅲ (n=10) ; 500 ml of 10% pentastarch solution was rapid infused intravenously before epidural anesthesia All data were collected before fluid infusion, at 15 min, at 30 min, at 45 min, at 60 min, at 120 min and at 180 min after epidural local anesthetic injection. The results are as follows. 1. SABP, DABP, HR, CVP and CO were decreased significantly (p<0.05) at 30, 45 minute after local epidural anesthetic injection in Group Ⅰ and Group Ⅱ. There was no any significant differences between two groups. 2. SABP, DABP, HR and CO were not changed significantly, Besides CVP was increased significantly (p<0.05) after 10% pentastarch solution infusion in group Ⅲ. 3. Changes of Hb were increased in group Ⅲ.

      • SCISCIESCOPUS

        Surgical outcome of metachronous hepatic metastases secondary to gastric cancer.

        Choi, Sae Byeol,Song, Jyewon,Kang, Chang Moo,Hyung, Woo Jin,Kim, Kyung Sik,Choi, Jin Sub,Lee, Woo Jung,Noh, Sung Hoon,Kim, Choong Bai G. Thieme 2010 Hepato-gastroenterology Vol.57 No.97

        <P>BACKGROUND/AIMS: The prognosis of hepatic metastasis from gastric carcinoma is dismal. A few patients are candidates for hepatic resection. The present study analyzed the oncologic outcomes of hepatic resection performed in metachronous hepatic metastasis from gastric cancer. METHODOLOGY: Between January 1986 and November 2007, 14 patients underwent hepatectomy for metachronous hepatic metastasis secondary to gastric adenocarcinoma. Clinicopathological data were reviewed retrospectively. RESULTS: The median interval between gastrectomy and hepatectomy was 12.9 months. The numbers of hepatic lesions were single in 9 patients, more than two in 5 patients. The overall survival rates following hepatectomy were 67.0% at 1 year, 38.3% at 3 year. The disease progression occurred in 10 patients in the remaining liver. CONCLUSION: Surgical resection could be a treatment option for the hepatic metastasis from gastric cancer. The comparison of efficacy between surgical resection and the other treatment modalities will be required.</P>

      • OB-44 : A case report of congenital CMV infection mimicking Dandy-Walker syndrome by prenatal ultrasonography

        ( Sae Kyung Choi ),( Joo Young Cheon ),( Mi Rang Choi ),( Jeong Ha Wie ),( Hyun Sun Ko ),( In Yang Park ),( Jong Chul Shin ) 대한산부인과학회 2012 대한산부인과학회 학술대회 Vol.99 No.-

        Cytomegalovirus (CMV) is the most common cause of intrauterine infection, affecting 0.3-2% of liveborn infants. Given that congenital CMV infection is a relatively common cause of sensorineural hearing loss (SNHL) and mental retardation, its antenatal diagnosis and prevention is a major challenge in perinatology. Perinatal infection may be suspected from abnormalities seen with sonography or magnetic resonance imaging (MRI). Findings include microcephaly, ventriculonmegaly, cerebral calcification, ascites, hepatomegaly, splenomegaly, hyperechoic bowel, hyprops, and oligohydramnios. But, findings by imaging studies are too variable to be used as diagnostic tool. In this report, we present a case of CMV infection which prenatal ultrasonographic findings revealed partial absence of cerebellar vermis mimicking Dandy-Walker syndrome.

      • SCISCIESCOPUS

        The preoperative positivity for serum hepatitis B e antigen did not affect overall survival after curative resection of hepatitis B virus-related hepatocellular carcinoma

        Choi, Gi Hong,Kim, Dong Hyun,Choi, Sae Byeol,Kang, Chang Moo,Kim, Kyung Sik,Choi, Jin Sub,Lee, Woo Jung,Han, Kwang Hyub,Chon, Chae Yoon,Kim, Byong Ro Blackwell Publishing Asia 2009 Journal of gastroenterology and hepatology Vol.24 No.3

        <P>Abstract</P><P>Background and Aim: </P><P>Previous studies have reported different risk factors for early and late intrahepatic recurrence after resection of hepatocellular carcinoma (HCC). However, the prognostic significance of the risk factors for early and late recurrence has not been clarified.</P><P>Methods: </P><P>A total of 190 Hepatitis B surface antigen-positive patients who received curative resection for HCC were reviewed. We investigated prognostic factors for disease-free and overall survival after resection, and further analyzed the relationship between significant prognostic factors and risk factors for early (≤14 months) and late (>14 months) intrahepatic recurrence.</P><P>Results: </P><P>The 5-year disease-free and overall survival rates were 43.9% and 71.5%, respectively. In multivariate analysis, adverse prognostic factors for disease-free survival were presence of serum HBeAg, perioperative transfusion, and the presence of portal vein invasion (PVI) and/or intrahepatic metastasis (IM). Multivariate analysis revealed that overall survival was associated with ICG R15, serum albumin, Edmondson–Steiner grade, and the presence of PVI and/or IM. Independent risk factors for early intrahepatic recurrence were perioperative transfusion and PVI and/or IM, whereas positivity for HBeAg was the only risk factor for late recurrence. In addition, post-recurrence survival in patients with late intrahepatic recurrence was completely comparable to that of patients who never experienced recurrence.</P><P>Conclusions: </P><P>The presence of serum HBeAg, the risk factor for late intrahepatic recurrence did not affect overall survival after resection because late recurrence was relatively well controlled by current available treatments. To further improve long-term surgical outcomes, effective treatment and preventive methods for early intrahepatic recurrence should be investigated.</P>

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