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SNS의 뉴스 콘텐츠 이용동기가 뉴스 콘텐츠 유형별 이용량에 미치는 영향 : 참여행위의 매개효과 검증을 통하여
장지연(Ji Yeon Chang),전가영(Ka Young Jeon),유세경(Sae Kyung Yu) 한국언론정보학회 2020 한국언론정보학보 Vol.104 No.-
본 연구는 변화하는 미디어 환경에서 사람들이 어떠한 목적을 가지고 소셜미디어에서 뉴스를 이용하는지 이용 동기를 알아보고, 대표적 콘텐츠 유형별 이용량에 영향을 미치는 이용자 참여행위의 매개효과 검증을 실시했다. 연구 결과, 유튜브 뉴스 콘텐츠를 이용하는 사람들은 다양성을 충족 받고자 하고, 자신과 유사한 견해를 가진 뉴스를 추구한다는 동기가 강했고, ‘좋아요’표시나 댓글 쓰기, 공유 행위 등 참여행위의 매개 효과를 검증한 결과, 유튜브 뉴스 콘텐츠 이용량에 유사견해의 추구 동기는 매개효과가 없는 직접효과만이 유의하고, 다양성 추구의 동기는 참여행위가 매개되지 않으면 이용량을 예측할 수 없는 완전매개효과가 있는 것으로 나타났다. 카드뉴스 콘텐츠에서는 편리성 및 맞춤제공의 동기와 습관적 소비 동기가 요인으로 추출되었지만 이용자 참여행위는 이용량에 대해 유의한 효과 없이 이용 동기가 이용량에 모두 직접적 영향을 미쳤다. 소셜미디어에 원문 그대로 재매개되는 언론사 뉴스 콘텐츠의 경우 다른 유형과는 차별적으로 시의성 충족의 동기가 가장 중요했다. 최근에 일어난 이슈를 실시간으로 소비하고자 하는 욕구와 더불어 의견 교환 및 견해의 비교 동기 역시 유의하게 나타나 기성 매체의 콘텐츠가 소셜미디어 플랫폼에서 새로운 의미로 재가공된다는 점을 확인했다. 재매개된 언론사 뉴스 이용량에 시의성 충족의 동기는 매개효과가 없는 직접효과만 유의했고, 의견교환 및 견해의 비교 동기는 이용자 참여행위의 완전매개효과를 확인했다. 이 연구는 소셜미디어를 활용한 뉴스 콘텐츠 생산과 유통, 소비과정에서 이용자들의 이용 동기와 참여행위를 고려한 전략을 모색할 수 있도록 돕고, 소셜미디어 뉴스의 균형과 조화를 위한 자료를 제공했다는 점에서 의의가 있다. This study identified the motivations for using 3 different news content types on social media platforms and verified mediating effects of user participatory behaviors that affect the usage of each news content type. Studies have shown that those who use YouTube news content have strong motivation to ‘seek for diversity’ and to ‘pursue news with similar views’. In addition, participatory actions: such as ‘like’, ‘writing comments‘ and ‘sharing‘ mediated ‘seeking for diversity’ motivation and the usage of YouTube news. However motivation for ‘pursuing news with similar views’ had no mediating effect. Card news usage showed that the motivation for ‘convenience and curation’ and ‘habitual consumption’ found to have strong positive relation, but the user participatory behavior had no significant mediating effect on the amount of use. Unlike other news contents, original news that are re-mediated via social media showed to have a positive relationship with the motivation for ‘timeliness’ and ‘exchanging opinions and comparing views’. This result confirmed that as original news content transported into social media, even if the content do not change the meaning for the usage change. The motivation for meeting ‘timeliness’ was only noted to have direct effects towards the usage without any mediated effects, but the motivation for ‘exchanging opinions and comparing views’ confirmed the complete mediating effect of user participation. The research is meaningful in that it helped to explore strategies that took into account users’ motives and participation in the process of producing, distributing and consuming news content using social media.
백서에서 자가 피부이식후 항T임파구 단일클론항체 분포에 관한 면역조직화학적 연구
朴晩圭,金慶助,任昌俊,高世勳 단국대학교 치의학연구소 1991 논문집 Vol.3 No.-
This article is intended to study histopathological and immunohistochemical response after autogenous full-thickness skin graft in rat. 12 male Sprague-Dawley rats were used as the experimental animals. A 1 cm×1 cm skin (0.7mm diameter) was taken on the right inguinal area of the rat. Another full-thickness skin graft (1cm × 1cm) was taken from the left inguinal area of the rat. And it was transplanted to the right inguinal area of the rat. The left side wound was closed directly. Light microscopic observation was made at the postoperative 1, 3, 8, 16 day, after the hematoxylin-Eosin staining of the 4u-thick paraffin embedded specimens and the immunohistochemical staining of the 10u-thick frozen specimens with mouse anti-rat monoclone antibodies and ABC staining kit. The results were as follows. 1. Electromicroscopic studies revealed interstitial tissue bleeding of transplanted autogenous skin. The response was severe in the 1 day group after operation, moderate in 3 day group, mild in 8 day group, and almost resolved in the 16 days group. 2. Electromicroscopic studies also revealed a mild monocyte response in the 3 day and 8 day groups. A histiocytic infiltrate was observed. There was a mild response in the 3 day group and moderate response in the 8 day group. 3. Immunohistochemically studies revealed a few pan T cells in the 1 day group, mild appearance of pan T cells and cyototoxic T cells in the 3 day group, a moderate infiltrate of pan T cells and helper T cells in the 8 day group, and total resolution of pan T cells in the 16 day group. 4. According to these finding, a strong inflammatory response was observed around transplanted autogenous skin in the 3 & 8 day groups. In the 16 day group this response had resolved histopathologically and immunohistologically.
Editorial : Alteration of Gut Microbiota and Efficacy of Probiotics in Functional Constipation
( Chang Hwan Choi ),( Sae Kyung Chang ) 대한소화기기능성질환·운동학회(구 대한소화관운동학회) 2015 Journal of Neurogastroenterology and Motility (JNM Vol.21 No.1
Article: Change of fecal flora and effectiveness of the short-term VSL#3 probiotic treatment in patients with functional constipation Kim SE, Choi CS, Park KS, et al
Mini-gel을 이용한 비방사성 SSCP의 위암 p53유전자 변이 검출
유경금(Kyung Kum Yoo),도재혁(Jae Hyuk Do),허철행(Cheol Heang Heo),문철(Cheol Moon),김형준(Hyung Jun Kim),이태진(Tae Jin Lee),유재형(Jae Hyeng Yoo),장진수(Jin Soo Chang),이상재(Sang Jea Lee),장세경(Sae Kyung Chang),박실무(Sill Moo Pa 대한소화기학회 1997 대한소화기학회지 Vol.29 No.5
N/A Background/Aims: p53 mutation was reported in many studies, but conventional PCR-SSCP protocol using radiolabeled PCR primers or nucleotides to generate a radioactive PCR products is cumbersome to handle. With the aim of a rapid and safe method for single-strand conformation polymorphism(SSCP) analysis of PCR products, we used Mini-SSCP method to detect the mutation of p53 gene of gastric cancer. Methods: In 27 pair of gastric cancer and normal tissues, PCR-SSCP was done with Mini-SSCP, and then Silver sequencing was done. Results: The p53 gene mutation of gastric cancer was found in 10 of 27(37%). Mutation of exon 4, 5 were 2, 5 cases and tnutation of exon 6, 7 mutation were 0, 3 cases respectively. Mutation rate was similar with other reports. P53 mutation was not correlated with stage, lymph node involvement and histological differentiation. Conclusions: Mini-SSCP method, modification of Cold-SSCP, greately increased our accessibility to detect polymorphisms with easiness and safeness. So, it is a useful method to detect genetic mutation. (Korean J Gastroenterol 1997;29:601-609)
의료관광 전략 수립 및 비즈니스 서비스 모델 설계에 관한 연구
장세경(Sae Kyung Chang),백종선(Jong Sun Baek) 한국전자거래학회 2017 한국전자거래학회지 Vol.22 No.3
세계의료관광 서비스의 시장 규모는 날로 커지고 있으며, 국내 의료관광 시장 또한 높은 성장세를 보이고 있다. 그러나 다양한 정보와 서비스가 정형화되어 있지 않고 정상적인 가격경쟁의 불가 등 의료 서비스 제공으로 인한 문제점이 대두되고 있는 실정이다. 이렇게 정형화 되지 않은 의료 서비스 제공으로 인한 문제점이 대두되고 있으며, 이를 개선하기 위해 본 논문에서는 의료 생태계 조사를 통하여 ICT 기반 한국형 의료관광 서비스 모델을 설계하였다. 우선적으로 국내외 의료 생태계 현황 분석을 진행하여 국내 시장에서의 의료관광 문제점을 파악하고 개선을 위한 주요한 방향성을 제시하여 전략을 수립하였다. 이를 반영하여 국내 실정에 맞으며 고객이 접근 가능하고 편리한 ICT 기반 의료관광 서비스 모델, 클라우드, O2O 서비스 기반 역경매 시스템, 빅데이터 기반 라이프사이클 관리 그리고 모바일 중심 헬퍼 서비스를 설계하였다. 본 논문에서 제안한 의료관광 서비스 모델은 고객에게 편리함을 제공하며 향후 한국 의료관광 문제점들을 해결하고 활성화에 기여하며 산업적으로도 파급력 있는 효과를 기대한다. The market for medical tourism services in the world is steadily increasing and the medical tourism market in the South Korea is also showing high growth. However, they have also problem such as informal various information and services, irregularity price competition etc. In order to solve this problem, We have designed a medical tourism service model based on ICT specific on domestic medical ecosystem. First, analysis trends of domestic and overseas medical ecosystem and identify current problem of medical tourism. In order to solve existed problem we also have designed a medical tourism strategy. Based on the strategy, we have designed business service model based on ICT platform for as fit as Korea medical tourism status. The proposed medical tourism business service model can provide usability to customer and also can solve current medical tourism problem. We expect industrial effect and contribution to the activation.
궤양성 대장염에서 점소 당항원 sTn 과 Tn 의 발현에 관한 연구
장무선(Moo Sun Chang),도재혁(Jae Hyuk Do),김형준(Hyung Jun Kim),유경금(Kyung Kum Yoo),박수정(Soo Jeong Park),문철(Cheol Moon),허철행(Cheol Heang Heo),김재규(Jae Gyu Kim),장세경(Sae Kyung Chang),박실무(Sil Moo Park),김미경(Mi Kyung K 대한내과학회 1997 대한내과학회지 Vol.52 No.1
N/A Objectives: Long standing observation, which may relate either to the causes or the effects of UC, reveals that there is a pronounced alteration of mucin such as quantitative and qualitative abnormalities of mucin glycoprotein. But recently in situ hybridization technique showed no specific difference in the expression of apomucin mRNA in UC. Therefore we investigated whether abnormality of mucin was originated from defect in glycosylation. And we also tried to find differences in the expression of Tn and sTn antigens between Korean and Jewish patients with UC. Methods: We performed the immunohistochemical staining using the monoclonal antibody of mucin carbohydrate antigens Tn and sTn in 19 patients with UC. Results: Tn and sTn antigens were not expressed throughout the crypt and surface epithelium in normal colon but both of mucin carbohydrates antigens were well expressed in mild UC, Tn antigen was seen in the surface epithelium with perinuclear pattern and sTn antigen was shown not only in surface but also in crypt epithelium. In severe UC, Tn antigen was well expressed, but sTn antigen was not expressed. Tn antigen seemed to be ex-pressed more frequently than sTn antigen with severity of inflammation. These results were similar in Korean and Jewish patients with UC. Conclusion: These results suggest that inflammatory bowel disease has some deterioration in the step of glycosylation in the cytoplasm and there was no racial difference in the expression of Tn and sTn antigen in Korean and Jewish patients with UC.