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RISS 인기검색어
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- 저자 : ( Rayon Kim ) (검색결과 4 건)
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The Structure of the Catalytic Domain of a Plant Cellulose Synthase and Its Assembly into Dimers
Olek, Anna T.,Rayon, Catherine,Makowski, Lee,Kim, Hyung Rae,Ciesielski, Peter,Badger, John,Paul, Lake N.,Ghosh, Subhangi,Kihara, Daisuke,Crowley, Michael,Himmel, Michael E.,Bolin, Jeffrey T.,Carpita, American Society of Plant Biologists 2014 The Plant cell Vol.26 No.7
<P>Small-angle x-ray scattering gives a glimpse at the solution structure of the catalytic domains of plant cellulose synthase and their dimerization. Dimerization through the plant-specific sequences of the catalytic domain provides important clues for how Zn-finger domains couple these fundamental scaffold units into large, multimeric synthase complexes.</P>
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Association between Ultrasonography Findings and Abnormal Karyotypes in Early Pregnancy Loss
( Jaeyoung Pae ),( Jaeyoung Park ),( Sinyoung Kim ),( Rayon Kim ),( Jeongha Wie ),( Hyun Sun Ko ),( In Yang Park ),( Jong Chul Shin ) 대한주산의학회 2020 Perinatology Vol.31 No.2
Objective: Chromosomal abnormality in the fetus is a major cause of early pregnancy loss (EPL). It is considered that maternal age is a risk factor of chromosomal abnormality in the fetus. The objective of this study was to evaluate the association between ultrasonography findings and abnormal karyotypes in EPL. Methods: This retrospective analysis assessed 217 cases of EPL occurring between 2009 and 2018, which have the results of cytogenetic analysis following miscarriage, as well as the ultrasonography finding. The correlations between the ultrasonography findings and the karyotypes were evaluated. Results: Of the 217 cases, after excluding cases with no mitotic cells, karyotypes analysis was performed in 190 cases. The overall rate of abnormal karyotypes was 32.1% (61/190). Mean maternal age was significantly higher in the abnormal karyotype group (35.66±4.22 vs. 33.79±4.02 years, respectively, P=0.006). The embryo/gestational sac ratios was significantly smaller in the abnormal karyotype group (0.3±0.18 vs. 0.43±0.3, P=0.022). In the multivariate logistic regression analysis, smaller embryo/gestational sac ratios (≤0.4) was a significant risk factor of abnormal karyotype (adjusted odds ratio [OR] 2.43, 95% confidence interval [CI]: 1.086-5.437, P=0.031), after the adjustment with the number of previous abortion. The chromosomal abnormality rate was significantly higher in male miscarriage (adjusted OR 2.36, 95% CI: 1.003-5.443, P=0.049). Conclusion: By identifying a predictive factor of chromosomal abnormalities in embryonic abortion, this study presented ultrasonography findings to consider cytogenetic analysis and an easy-to-use cut off value, small embryo/gestational sac ratio (≤0.4) at a patient’s request of chromosomal study in the fetus.
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Risk-Factor analysis of increased hemorrhage during cesarean myomectomy
( Ji Young Kwon ),( Ji Hea Byun ),( Inhye Shin ),( Subeen Hong ),( Rayon Kim ),( In Yang Park ) 대한산부인과학회 2020 대한산부인과학회 학술대회 Vol.106 No.-
Objective: We intended to identify the risk factors of increasing complications such as hemorrhage on occasions of a combined operation of myomectomy with cesarean section of patients with uterine myoma. Methods: A retrospective cohort study was done of all patients who underwent cesarean myomectomy for intramural leiomyoma during a cesarean section at a single university hospital. Cases identified with subserosal leiomyoma, placental disorder, and comorbid conditions related to coagulopathy were excluded. We entered factors found to be significantly associated with operative hemorrhage into multivariate logistic regression analysis to identify risk factors for hemorrhage. Results: A total of 302 women underwent cesarean myomectomy during the study period. Among these women, 212 pregnant women met the inclusion criteria. The proportion of women requiring transfusion was 6.6%. Postoperative ileus or fever occurred in 6 women (2.8%). Operative hemorrhage occurred in 23 women (10.8%). Women in the hemorrhage group had significantly more intraoperative blood loss, more hemoglobin drop, longer operative time and a longer postoperative stay in hospital than did women in the non-hemorrhage group (p = 0.007, < 0.001, 0.016, and < 0.001, respectively). Removed leiomyomas in the hemorrhage group showed significantly larger diameters (p = 0.048) and lower segmental location than did those in the control (p < 0.001). Multiple logistic regression analysis demonstrated that the parameters of leiomyoma, including lower segmental location (odds ratio [OR], 6.952; 95% confidence interval [CI], 2.342 - 20.638, p < 0.001) and the diameter (OR, 1.207; 95% CI, 1.047 - 1.391, p = 0.009), were significant independent predictors of hemorrhage after cesarean myomectomy. Conclusion: We identified that the cesarean myomectomy employed for the uterine myoma found with sizes below 10 cm and situated at either the uterine fundus or the middle portion of the uterus would leave no further complications, such as hemorrhage.
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( Jae Seong Lee ),( Gi Youn Hong ),( Byung Joon Park ),( Hyejin Hwang ),( Rayon Kim ),( Tae Eung Kim ) 대한산부인과학회 2016 Obstetrics & Gynecology Science Vol.59 No.5
We present a case of retained placenta accreta treated by high-intensity focused ultrasound (HIFU) ablation followed by hysteroscopic resection. The patient was diagnosed as submucosal myoma based on ultrasonography in local clinic. Pathologic examination of several pieces of tumor mass from the hysteroscopic procedure revealed necrotic chorionic villi with calcification. HIFU was performed using an ultrasound-guided HIFU tumor therapeutic system. The ultrasound machine had been used for real-time monitoring of the HIFU procedure. After HIFU treatment, no additional vaginal bleeding or complications were observed. A hysteroscopic resection was performed to remove ablated placental tissue 7 days later. No abnormal vaginal bleeding or discharge was seen after the procedure. The patient was stable postoperatively. We proposed HIFU and applied additional hysteroscopic resection for a safe and effective method for treating retained placenta accreta to prevent complications from the remaining placental tissue and to improve fertility options.
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