http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
- 中文 을 입력하시려면 zhongwen을 입력하시고 space를누르시면됩니다.
- 北京 을 입력하시려면 beijing을 입력하시고 space를 누르시면 됩니다.
RISS 인기검색어
- 검색키워드
- 저자 : ( Rahmi Yilmaz ) (검색결과 2 건)
- 무료
- 기관 내 무료
- 유료
-
( Tolga Yildirim ),( Hadim Akoglu ),( Rahmi Yilmaz ),( Gonca Eldem ),( Tuncay Hazirolan ),( Tuncay Aki ),( Mustafa Arici ),( Bulent Altun ),( Yunus Erdem ) 대한내과학회 2014 대한내과학회 추계학술대회 Vol.2014 No.1
Background: Immunosuppressive protocols decreased the rates of acute rejection in kidney transplantation however long term graft survival has not changed signifi cantly. Nephron underdosing may be one of the factors affecting the long term prognosis of the transplanted kidney. Aim of this study was to determine the impact of volume of transplanted kidney on long term allograft functions. Methods: The study was conducted among sixty-two living renal transplant recipients (41 male, 21 female; mean age 30.6±10.2 years) who underwent transplantation between years 2003-2007 and their respective donors (22 male, 40 female; age 41.9±9.9 years). Patients that suffered graft loss due to any cause within fi ve years after transplantation were excluded. Volume of the transplanted kidneys had been measured preoperatively via 3-D helical computerized tomography. Transplanted kidney volume/ recipient weight (Vol/weight) was calculated for each donor-recipient pair. Subjects were divided into two groups according to the median value of Vol/weight (2.35 cm3/ kg). Glomerular fi ltration rates (GFR) of the recipients were calculated for fi ve years. Results: First and third year GFR`s of the patients was significantly higher in Vol/ weight>2.35 cm3/kg group compared to Vol/weight<2.35 cm3/kg group (73.7±17.6 vs. 61.6±19.3, p=0.01 and 72.3±20.7 vs. 60.0±17.3, p=0.01 respectively). However fi fth year GFR was similar in both groups (64.5±16.9 and 56.6±21.7, p=0.11). There was a signifi cant correlation between Vol/weight and both fi rst and third year GFR`s (r=0.409, p<0.001 and r=0.429, p<0.001; respectively). The correlation was not observed with the fi fth year GFR (r=0.133, p=0.303). Conclusions: Volume of transplanted kidney adjusted for recipient weight is a signifi - cant predictor of early but not late graft functions.
-
Erdem, Merve Guler,Cinkilic, Nilufer,Vatan, Ozgur,Yilmaz, Dilek,Bagdas, Deniz,Bilaloglu, Rahmi Asian Pacific Journal of Cancer Prevention 2012 Asian Pacific journal of cancer prevention Vol.13 No.10
Vanillic acid, a vegetable phenolic compound, is a strong antioxidant. The aim of the present study was to determine its effects on mitomycin C-induced DNA damage in human blood lymphocyte cultures in vitro, both alone and in combination with mitomycin C (MMC). The cytokinesis block micronucleus test and alkaline comet assay were used to determine genotoxic damage and anti-genotoxic effects of vanillic acid at the DNA and chromosome levels. MMC induced genotoxicity at a dose of $0.25{\mu}g/ml$. Vanillic acid ($1{\mu}g/ml$) significantly reduced both the rates of DNA damaged cells and the frequency of micronucleated cells. A high dose of vanillic acid ($2{\mu}g/ml$) itself had genotoxic effects on DNA. In addition, both test systems showed similar results when tested with the negative control, consisting of dimethyl sulfoxide (DMSO) in combination with vanillic acid ($1{\mu}g/ml$)+MMC. In conclusion, vanillic acid could prevent oxidative damage to DNA and chromosomes when used at an appropriately low dose.
연관 검색어 추천
이 검색어로 많이 본 자료
활용도 높은 자료
