http://chineseinput.net/에서 pinyin(병음)방식으로 중국어를 변환할 수 있습니다.
변환된 중국어를 복사하여 사용하시면 됩니다.
Rae Francis C. Quilantang ; Kimberly Nicole Panis Quilantang Academy of Mobility Humanities 2024 Mobility Humanities Vol.3 No.1
This essay explores the cultural significance of jeepney art and symbolism in the Philippines, especially within the ongoing Public Utility Vehicle Modernisation Program (PUVMP). Employing insights from automobility studies, it investigates how these cultural symbols distinctly reflect and shape Filipino identities and narratives. Through semiotic analysis a variety of motifs reveal values, aspirations, and social realities unique to Filipino culture. The article also emphasises the role of jeepneys as essential components of the Philippines’ unique transportation system, and as integral elements of both urban landscapes and social interactions. This aspect is further elaborated by considering the potential cultural implications of the jeepney modernisation program. The discussion underscores the importance of understanding the socio-political dimensions of this transformation. Moreover, the paper brings to light the critical need for further research into these socio-cultural impacts. This is particularly relevant as the modernization program progresses, potentially altering the traditional jeepney landscape. Concluding, the paper suggests that future modernisation efforts in the Philippines should thoughtfully consider preserving cultural heritage. This could involve incorporating traditional jeepney art into the design of new vehicles, symbilising an important balance between modernisation and cultural preservation. This signifies the importance of balancing modernisation with cultural preservation, a theme echoed in urban mobility studies.
( Norman G. Quilantang ),( Ju Sung Lee ),( Seo Hyun Ryu ),( Se Hoon Park ),( Jae Sang Byun ),( Je Sung Chun ),( Sonia D. Jacinto ),( Sanghyun Lee ) 한국응용생명화학회(구 한국농화학회) 2018 Journal of Applied Biological Chemistry (J. Appl. Vol.61 No.2
The inhibition of aldose reductase (AR) has been shown to prevent the progression of the many complications associated with diabetic hyperglycemia. Several compounds purified from various plant sources have exhibited potent inhibition against AR. In this study, the inhibitory effects of the methanol extracts of the flowers of Synurus excelsus and Weigela subsessilis on AR were determined in vitro. Scopolin and scopoletin are coumarins isolated from the flowers of S. excelsus and W. subsessilis; and quercetin is a known AR inhibitor present in many flowers. To determine and quantify their presence in both plants, HPLC-UV analysis of all three compounds was performed. S. excelsus and W. subsessilis showed potent inhibition against AR having IC<sub>50</sub> values of 0.17 and 0.14 μg/mL, respectively. The concentration of scopolin in S. excelsus and W. subsessilis were 34.71 and 174.14 mg/g extract, respectively. Scopoletin was detected in S. excelsus at 3.41 mg/g extract, whereas quercetin was not detected in both plants. This study shows that S. excelsus and W. subsessilis exhibited promising AR inhibitory effects and are both sources of coumarins.
Norman G. Quilantang,류서현,박세훈,변재상,전제성,이주성,Joyce P. Rodriguez,윤영석,Sanghyun Lee,이상현 한국원예학회 2018 Horticulture, Environment, and Biotechnology Vol.59 No.6
The methanol extracts of flowers obtained from 67 plant species were screened for their inhibitory activity on aldose reductase(AR). Alnus japonica , Aster spathulifolius , Chionanthus retusus , Morus bombycis , Crysanthemum boreale , Persicariatinctoria , Platycarya strobilacea , and Serratula coronata var. insularis exhibited potent aldose reductase inhibitory (ARI)activity. HPLC-UV analysis of quercetin, an AR inhibitory flavonoid, was performed on extracts showing strong ARI activity. Quercetin was detected in C. retusus , C. boreale , P. tinctoria , and S. coronata var. insularis at concentrations of 1.33,1.56, 0.82, and 3.37 mg g −1 extract, respectively, indicating that quercetin contributed to the ARI activity of these extracts. In the samples in which quercetin was absent, other compounds may be responsible for their potent ARI activity. Theseresults serve as a basis for further studies regarding the bioactive components responsible for the inhibitory eff ects of variousfl ower extracts on AR activity.
Aldose reductase inhibition of Rosa hybrida petals and its active component, kaempferol
Norman G. Quilantang,Carlo A. Limbo,이주성,Sonia D. Jacinto,Sung-Kwon Moon,Sanghyun Lee 한국원예학회 2020 Horticulture, Environment, and Biotechnology Vol.61 No.3
The aldose reductase inhibitory activity of extracts from Rosa hybrida petals was evaluated, and a bioactive fl avonoid,kaempferol, was isolated from petals via bioassay-guided isolation. Kaempferol was isolated from the ethyl acetate fractionof R. hybrida and was shown to exhibit strong inhibition against aldose reductase (IC 50 = 0.02 μM). Quantitative analyses ofkaempferol in R. hybrida petals, diff erent fl ower parts, and diff erent Rosa species were also performed using high-performanceliquid chromatography. This study is the fi rst to establish that R. hybrida contains kaempferol and that the light-pinkpetals of this edible rose species exhibit the highest content of the naturally occurring aldose reductase inhibitor. The resultsof this study suggested the potential role of R. hybrida petals in the treatment and management of diabetic complicationsvia aldose reductase inhibition.
Norman G. Quilantang,이기호,이동구,이주성,조은주,김현영,이상현 한국생약학회 2017 Natural Product Sciences Vol.23 No.4
A quantitative analysis of bakkenolide D in the different parts of Petasites japonicus and Farfugium japonicum was performed by HPLC. A gradient HPLC elution system with a mobile phase consisting of water: acetonitrile solution (20:80 to 0:100 for 45 min) was followed and an INNO C18 column was used for the chroma- tographic separation. The injection volume, flow rate, and UV detection were 10 mL, 1 mL/min, and 290 nm, respectively. Results show that both species showed the highest amount of bakkenolide D in the roots being 107.203 and 166.103 mg/g for P. japonicas and F. japonicum, respectively. Content analysis on the different parts of both plants displayed remarkably lower values which ranged from 0.403 - 4.419 and 7.252 - 32.614 mg/g for P. japonicas and F. japonicum, respectively. The results show that the roots of both plants are rich in bakkenolide D showing a promising use in the development of nutraceuticals and industrial application of the compound.
Acer okamotoanum Inhibit the Hydrogen Peroxide-Induced Oxidative Stress in C6 Glial Cells
최수연,김지현,Norman G. Quilantang,이상현,조은주 한국생약학회 2018 Natural Product Sciences Vol.24 No.3
Chronic oxidative stress due to the accumulation of reactive oxygen species (ROS) in neuronal cells ultimately leads to neurodegenerative diseases. The use of natural therapies for the prevention of ROS-induced cell damage and for the treatment of neurodegenerative disorders has shown promising results. In this study, we evaluated the neuroprotective effects of the ethyl acetate (EtOAc) fraction of A. okamotoanum against the hydrogen peroxide (H2O2)-induced oxidative stress in C6 glial cells. Results show that cell viability was decreased in cells incubated with H2O2, whereas the addition of EtOAc fraction treatments in such cells significantly increased viability. The EtOAc fraction showed the highest inhibitory activity against ROS production and it also decreased the expressions of inflammatory proteins including cyclooxygenase-2, inducible nitric oxide synthase and interleukin-1b. Furthermore, the EtOAc fraction inhibited apoptosis by regulating the protein expressions cleaved caspase -9, -3, poly ADP ribose polymerase, Bax and Bcl-2. Therefore, these results show that the EtOAc fraction of A. Okamotoanum exhibits neuroprotective effects against H2O2 induced oxidative damage by regulating the inflammatory reaction and apoptotic pathway.
Quantitative Analysis of Dammarane-type Ginsenosides in Different Ginseng Products
이동구,Norman G. Quilantang,이주성,Paul John L. Geraldino,김현영,이상현 한국생약학회 2018 Natural Product Sciences Vol.24 No.4
Ginseng products available in different forms and preparations are reported to have varied bioactivities and chemical compositions. In our previous study, four new dammarane-type ginsenosides were isolated from Panax ginseng, which are ginsenoside Rg18 (1), 6-acetyl ginsenoside Rg3 (2), ginsenoside Rs11 (3), and ginsenoside Re7 (4). Accordingly, the goal of this study was to determine the distribution and content of these newly characterized ginsenosides in different ginseng products. The content of compounds 1 - 4 in different ginseng products was determined via HPLC-UV. The samples included ginseng roots from different ginseng species, roots harvested from different localities in Korea, and samples harvested at different cultivation ages and processed under different manufacturing methods. The four ginsenosides were present at varying concentrations in the different ginseng samples examined. The variations in their content could be attributed to species variation, and differences in cultivation conditions and manufacturing methods. The total concentration of compounds 1 - 4 were highest in ginseng obtained from Geumsan (185 ?g/g), white-6 yr ginseng (150 ?g/g), and P. quinquefolius (186 ?g/g). The results of this study provide a basis for the optimization of cultivation conditions and manufacturing methods to maximize the yield of the four new ginsenosides in ginseng.
이주성,Norman G. Quilantang,남궁우,Xiang-Lan Piao,정미자,이상현 한국생약학회 2018 Natural Product Sciences Vol.24 No.3
To determine the optimum extraction conditions that give the highest yield of isoquercitrin and caffeic acid from Aster scaber, the effects of four extraction variables (solvent concentrations, extraction time, number of repeated extraction, and solvent volumes) on isoquercitrin and caffeic acid yield was examined via HPLC-UV. Our results showed that the highest extract and isoquercitrin yield were observed when A. scaber was extracted with 450 mL distilled water for 8 hr repeatedly for three times. In case of caffeic acid, the content was higher in the two repeated extracts. Also, content analysis of isoquercitrin in Aster species was performed in which A. fastigiatus, A. ageratoides, and A. scaber exhibited the highest isoquercitrin content at 6.39, 5.68, and 2.79 mg/g extract, respectively. In case of caffeic acid, the highest content of A. scaber and A. glehni was 0.64 and 0.56 mg/g extract, respectively. This study reports an optimized method for extraction of isoquercitrin and caffeic acid from A. scaber and evaluates potential sources of the compounds.
조성훈,Norman G. Quilantang,이주성,김영미,김호방,조은주,정용수,이상현 한국생약학회 2018 Natural Product Sciences Vol.24 No.1
Phytochemical analysis of Boehmeria nivea (Bn) leaves by medium pressure liquid chromatography led to the isolation of a flavonoid glycoside identified by spectroscopic analysis as rutin. The amount of rutin in the leaves of Bn harvested from nine regions in South Korea (Bn 1-9) which were collected on the months of June, July, August, and September was determined by HPLC-UV analysis. A gradient elution program that utilizes a Discovery? C18 (4.6 ? 250 mm, 5 mm) column and mobile phase composed of 1% acetic acid-water: acetonitrile (90:10 to 60:40 for min) was followed. The injection volume and flow rate were 10 ml and 1 mL/ min, respectively. UV detection was set at 350 nm. Results show that Bn-8 harvested in September reported the highest content of rutin among the samples analyzed. This study provides a basis for the optimal harvest time of Bn which maximizes the yield of rutin.
Determination of Silybin B in the Different Parts of Silybum marianum using HPLC-UV
Joyce P. Rodriguez,Norman G. Quilantang,이주성,이정민,김현영,심재숙,이상현 한국생약학회 2018 Natural Product Sciences Vol.24 No.2
Silymarin is the standardized extract from Silybum marianum which consists mainly of flavonoids and polyphenols. It is highly regarded for its hepatoprotective ability. Silybin B is a flavonolignan and one of the active components of silymarin. The content of silybin B in various parts of S. marianum was analyzed by HPLC-UV. Results show that the extract of seeds contain the highest amount of silybin B (7.434 mg/g DW). The petioles of S. marianum showed a low content of silybin B. This study revealed that seeds of S. marianum contain high amount of silybin B and could be a good source of the compound.