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- 저자 : ( Pyong Eun Park ) (검색결과 16 건)
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元炳旿,朴眞永,金恩英,金和貞 경희대학교 한국조류연구소 1993 연구보고 Vol.4 No.-
1. 1989년부터 1992년까지 동계에 한강의 서울수계에서 관찰한 조류는 총 39종, 최대 개체수는 27,615개체이며, 우점종은 흰죽지이다. 2. 1993년 2월부터 4월까지 한강하류에서 관찰한 조류는 총 38종, 최대개체수는 110,989개체이다. 최우점종은 흰죽지이며, 청둥오리, 고방오리 및 큰기러기의 순이었다. 3. 1992년 3월부터 5월까지 밤섬에서 관찰한 조류는 38종, 최대 개체수는 2,327개체이다. 최우점종은 청둥오리이며, 흰뺨검둥오리, 쇠오리 및 비오리의 순이었다. 4. 밤섬의 번식조류는 흰뺨검둥오리, 청둥오리 및 깝작도요이며, 꼬마물떼새와 쇠제비갈매기는 번식장소의 감소로 크게 줄어들었다. 5. 조류의 번식기간인 4~7월과 월동기간인 12~2월에는 밤섬의 출입을 엄격히 통제해야 하며, 인공 자갈못의 조성, 인공 새집의 가설, 먹이 공급 등을 통한 장기적인 보호 방안이 필요하다. 6. 행주대교에서 최근에 세워진 오두산통일전망대까지 약 25㎞에 이르는 한강하류지역은 재두루미, 개리, 큰기러기, 쇠기러기 및 말똥가리류, 수리류, 개구리매류 등 맹금류를 포함하는 10만마리 이상의 대집단이 도래하는 지역이다. 따라서 현재 천연기념물지역으로 지정된 한강하구지역은 수금류의 보호를 위해 위에 언급한 지역을 포함하여 확대지정하여야만 한다. 1. A total of 39 species with a maximum individual number of 27,615 of waterbirds was observed on the Han River in Seoul during the winter periods of 1982-1992, among which the most dominant species was Aythya ferina. 2. A maximum count of 110,989 individuals of 38 species were recorded from February to April 1993 on Han River estuary. The most dominant species was Aythya ferina followed by Anas platyrhynchos, A. acuta and Anser fabalis. 3. A maximum count of 2,327 individuals of 38 species were made during the bird census on Pam Islet, among which the most dominant species was Anas platyrhynchos followed by A. poecilorhyncha, A. crecca and Mergus merganser. 4. The species of birds breeding on Pam Islet were Anas platyrhynchos, A. poecilorhyncha and Tringa hypoleucos. The number of Charadrius dubius and Sterna albifrons was greatly declined due to the decrease of their breeding sites. 5. People coming to Pam Islet should be restricted during the breeding season from April to June and the wintering season from December to February. Long-term protection measures, such as artificial gravel pits and nests, and feed, are necessary for the waterbirds inhabiting this islet. 6. The downstream of the Han River stretching about 25㎞ from Haengju Bridge to the Han River estuary, where the unification observatory has recently been erected, becomes the wintering site of more than 100,000 waterfowl including rare spcies such as White-naped crane, Swan goose, Bean goose, White-fronted goose; and birds of prey such as buzzards, eagles, and harriers. Therefore, the present natural monument of the Han River estuary should be expanded by legislation to include the downstream of the Han River mentioned above for the protection of waterfowl.
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Radiation Safety and Education in the Applicants of the Final Test for the Expert of Pain Medicine
Park, Pyong-Eun,Park, Jung-Min,Kang, Joo-Eun,Cho, Jae-Hun,Cho, Suk-Ju,Kim, Jae-Hun,Sim, Woo-Seog,Kim, Yong-Chul The Korean Pain Society 2012 The Korean Journal of Pain Vol.25 No.1
Background: The C-arm fluoroscope is known as the most important equipment in pain interventions. This study was conducted to investigate the completion rate of education on radiation safety, the knowledge of radiation exposure, the use of radiation protection, and so on. Methods: Unsigned questionnaires were collected from the 27 pain physicians who applied for the final test to become an expert in pain medicine in 2011. The survey was composed of 12 questions about the position of the hospital, the kind of hospital, the use of C-arm fluoroscopy, radiation safety education, knowledge of annual permissible radiation dose, use of radiation protection, and efforts to reduce radiation exposure. Results: In this study, although most respondents (93%) had used C-arm fluoroscopy, only 33% of the physicians completed radiation safety education. Even though nine (33%) had received education on radiation safety, none of the physicians knew the annual permissible radiation dose. In comparing the radiation safety education group and the no-education group, the rate of wearing radiation-protective glasses or goggles and the use of radiation badges or dosimeters were significantly higher in the education group. However, in the use of other protective equipment, knowledge of radiation safety, and efforts to reduce radiation exposure, there were no statistical differences between the two groups. Conclusions: The respondents knew very little about radiation safety and had low interest in their radiation exposure. To make the use of fluoroscopy safer, additional education, as well as attention to and knowledge of practices of radiation safety are required for pain physicians.
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Radiation Safety and Education in the Applicants of the Final Test for the Expert of Pain Medicine
( Pyong Eun Park ),( Jung Min Park ),( Joo Eun Kang ),( Jae Hun Cho ),( Suk Ju Cho ),( Jae Hun Kim ),( Woo Seog Sim ),( Yong Chul Kim ) 대한통증학회 2012 The Korean Journal of Pain Vol.25 No.1
Background: The C-arm fluoroscope is known as the most important equipment in pain interventions. This study was conducted to investigate the completion rate of education on radiation safety, the knowledge of radiation exposure, the use of radiation protection, and so on. Methods: Unsigned questionnaires were collected from the 27 pain physicians who applied for the final test to become an expert in pain medicine in 2011. The survey was composed of 12 questions about the position of the hospital, the kind of hospital, the use of C-arm fluoroscopy, radiation safety education, knowledge of annual permissible radiation dose, use of radiation protection, and efforts to reduce radiation exposure. Results: In this study, although most respondents (93%) had used C-arm fluoroscopy, only 33% of the physicians completed radiation safety education. Even though nine (33%) had received education on radiation safety, none of the physicians knew the annual permissible radiation dose. In comparing the radiation safety education group and the no-education group, the rate of wearing radiation-protective glasses or goggles and the use of radiation badges or dosimeters were significantly higher in the education group. However, in the use of other protective equipment, knowledge of radiation safety, and efforts to reduce radiation exposure, there were no statistical differences between the two groups. Conclusions: The respondents knew very little about radiation safety and had low interest in their radiation exposure. To make the use of fluoroscopy safer, additional education, as well as attention to and knowledge of practices of radiation safety are required for pain physicians. (Korean J Pain 2012; 25: 16-21)
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Matrix Metalloproteinase-8 Plays a Pivotal Role in Neuroinflammation by Modulating TNF-α Activation
Lee, Eun-Jung,Han, Jeong Eun,Woo, Moon-Sook,Shin, Jin A.,Park, Eun-Mi,Kang, Jihee Lee,Moon, Pyong Gon,Baek, Moon-Chang,Son, Woo-Sung,Ko, Young Tag,Choi, Ji Woong,Kim, Hee-Sun The American Association of Immunologists, Inc. 2014 JOURNAL OF IMMUNOLOGY Vol.193 No.5
<P>Matrix metalloproteinases (MMPs) play important roles in normal brain development and synaptic plasticity, although aberrant expression of MMPs leads to brain damage, including blood–brain barrier disruption, inflammation, demyelination, and neuronal cell death. In this article, we report that MMP-8 is upregulated in LPS-stimulated BV2 microglial cells and primary cultured microglia, and treatment of MMP-8 inhibitor (M8I) or MMP-8 short hairpin RNA suppresses proinflammatory molecules, particularly TNF-α secretion. Subsequent experiments showed that MMP-8 exhibits TNF-α–converting enzyme (TACE) activity by cleaving the prodomain of TNF-α (A<SUP>74</SUP>/Q<SUP>75</SUP>, A<SUP>76</SUP>/V<SUP>77</SUP> residues) and, furthermore, that M8I inhibits TACE activity more efficiently than TAPI-0, a general TACE inhibitor. Biochemical analysis of the underlying anti-inflammatory mechanisms of M8I revealed that it inhibits MAPK phosphorylation, NF-κB/AP-1 activity, and reactive oxygen species production. Further support for the proinflammatory role of microglial MMP-8 was obtained from an in vivo animal model of neuroinflammatory disorder. MMP-8 is upregulated in septic conditions, particularly in microglia. Administration of M8I or MMP-8 short hairpin RNA significantly inhibits microglial activation and expression/secretion of TNF-α in brain tissue, serum, and cerebrospinal fluid of LPS-induced septic mice. These results demonstrate that MMP-8 critically mediates microglial activation by modulating TNF-α activity, which may explain neuroinflammation in septic mouse brain.</P>
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퇴원한 만성 정신 질환자의 삶의 질과 영향 요인에 관한 연구
한금선,이평숙,박은영 대한간호학회정신간호학회 2001 정신간호학회지 Vol.10 No.3
The purpose of this study was to investigate the factors influencing quality of life of chronic mental illness. The subjects of this study were 190 patients with chronic mental illness diagnosed by physician, over the age of 20, living in Seoul, Korea, during the period from May, 2000 to December, 2000. The instruments for this study were the quality of life scale by RoYooJa(1979), the self-esteem scale by Rogenberg(1965), social support scale by ParkJiWon(1985), coping behavior scale by Shirley Zeitlin(1978)m self efficacy scale by Sherer et. al(1982), and Rand mental health inventory(1979). The data were analyzed using descriptive statistics, Pearson correlation coefficients, and stepwise multiple regression. The results of this study are as follows: 1. The quality of life showed significant positive correlation with self-esteem(r=0.75, p=0.00), self-efficacy(r=0.53, p=0.00), social support(r=0.49, p=0.00), self-oriented coping(r=0.36, p=0.00), and environment-oriented coping (r=0.34, p=0.00). 2. The quality of life showed significant negative correlation with anxiety(r=-0.73, p=0.00), depression(r=-0.58, p=0.000), and psychological distress(r=-0.35, p=0.000). 2. Stepwise multiple regression analysis revealed that the most powerful predictor of quality of life was self esteem(36%). A combination of self esteem, social support, self efficacy, psychological distress, self oriented coping, and environment oriented coping behavior account for 55% of the variance in quality of life in chronic mental illness. From the results of this study, it is suggested to develop and apply comprehensive intervention program for improve quality of life in chronic mental illness.
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( Mi Na Song ),( Pyong Gon Moon ),( Jeong Eun Lee ),( Minkyun Na ),( Wonku Kang ),( Yee Soo Chae ),( Ji Young Park ),( Hoyong Park ),( Moon Chang Baek ) 영남대학교 약품개발연구소 2013 영남대학교 약품개발연구소 연구업적집 Vol.23 No.0
This study presents a proteomic method that differentiates between matched normal and breast tumor tissues from ductal carcinoma in situ (DCIS) and invasive carcinoma from Korean women, to identify biomarker candidates and to understand pathogenesis of breast cancer in protein level. Proteins from tissues obtained by biopsy were extracted by RIPA buffer, digested by the gel-assisted method, and analyzed by nano-UPLC-MS/MS. From proteomic analysis based on label-free quantitation strategy, a non-redundant list of 298 proteins was identified from the normal and tumor tissues, and 244 proteins were quantified using IDEAL-Q software. Hierarchical clustering analysis showed two patterns classified as two groups, invasive carcinoma and DCIS, suggesting a difference between two carcinoma at the protein expression level as expected. Differentially expressed proteins in tumor tissues compared to the corresponding normal tissues were related to three biological pathways: antigen-processing and presentation, glycolysis/gluconeogenesis, and complement and coagulation cascades. Among them, the up-regulation of calreticulin (CRT) and protein disulfide isomerase A3 (PDIA3) was confirmed by Western blot analysis. In conclusion, this study showed the possibility of identifying biomarker candidates for breast cancer using tissues and might help to understand the pathophysiology of this cancer at the protein level.
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