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      • KCI등재

        Packing trees into complete k-partite graph

        Yanling Peng,Hong Wang 대한수학회 2022 대한수학회보 Vol.59 No.2

        In this work, we confirm a weak version of a conjecture proposed by Hong Wang. The ideal of the work comes from the tree packing conjecture made by Gy\'arf\'as and Lehel. Bollob\'as confirms the tree packing conjecture for many small tree, who showed that one can pack $T_1,T_2,\ldots,T_{n/\sqrt{2}}$ into $K_n$ and that a better bound would follow from a famous conjecture of Erd\H{o}s. In a similar direction, Hobbs, Bourgeois and Kasiraj made the following conjecture: Any sequence of trees $T_1,T_2,\ldots,T_n$, with $T_i$ having order $i$, can be packed into $K_{n-1,\lceil n/2\rceil}$. Further Hobbs, Bourgeois and Kasiraj \cite{3} proved that any two trees can be packed into a complete bipartite graph $K_{n-1,\lceil n/2\rceil}$. Motivated by the result, Hong Wang propose the conjecture: For each $k$-partite tree $T(\mathbb{X})$ of order $n$, there is a restrained packing of two copies of $T(\mathbb{X})$ into a complete $k$-partite graph $B_{n+m}(\mathbb{Y})$, where $m=\lfloor\frac{k}{2}\rfloor$. Hong Wong \cite{4} confirmed this conjecture for $k=2$. In this paper, we prove a weak version of this conjecture.

      • KCI등재후보

        The 8th Biennial Meeting of the Asian Society of Gynecologic Oncology, December 1st to 3rd, 2023

        Heng-Cheng Hsu,김재원,박정열,서동훈,김세익,Jen-Ruei Chen,Peng-Hui Wang 대한부인종양학회 2024 Journal of Gynecologic Oncology Vol.35 No.2

        As per the 2018 GLOBOCAN database, Asia accounted for 48.7% (637,761) of new gynecologiccancer cases and 50.1% (305,000) of gynecologic cancer deaths [1]. Recognizing the distinctdifferences in genetic background, cancer epidemiology, disease characteristics, and socio-cultural environment between Asian and non-Asian women, it is noteworthy that much ofthe experimental evidence guiding clinical gynecologic oncology practices has historicallybeen drawn from studies in Western populations. Established in 2008, the Asian Society ofGynecologic Oncology (ASGO) ser ves as a key organization in Asia, dedicated to advancingthe study, prevention, and treatment of gynecological cancer through scientific exchange,regional/international collaboration, educational initiatives, and fostering camaraderieamong its members [2]. Presently, ASGO boasts members from over 10 countries in Asia. Building on the success of the previous meetings held in Tokyo (2009) [3], Seoul (2011)[4], Kyoto (2013) [5], Seoul (2015) [6], Tokyo (2017) [7], Incheon (2019) [8], and Bangkok(2021) [9], the eighth Biennial Meeting of ASGO took place at the state-of-the-art HNBKInternational Convention Center in Taipei, Taiwan, from December 01 to 03, 2023. Theoverarching theme for this event was “Reunion to Overcome Gynecologic Cancer in Asia.”Notably, due to the impact of the coronavirus disease 2019 pandemic in 2021, the meetingwas transformed into a hybrid format. This gathering marked a significant milestone as thefirst in-person Pan-Asia meeting focused on gynecological cancer following the pandemic. Additionally, it is worth highlighting that this was the inaugural ASGO meeting held outsideof Korea and Japan, underscoring the broadening geographical scope and global impactof the conference. Professor Peng-Hui Wang and Jae-Weon Jim chaired the organizingcommittee. ASGO 2023 witnessed the participation of 633 attendees from 17 countries,featuring 152 honored speakers and chairs from 12 countries. The event included 44 oral/surgical video presentations and 187 poster presentations, covering a diverse range ofscientific topics, from fundamental principles of gynecological cancer care to advanced, high-technology practices rooted in cutting-edge research (Table 1). Photos from the meetingare accessible on the official meeting website (http://tinyurl.com/26xtts2f ).

      • KCI등재

        Experimental study on seismic behavior of exterior composite beam-to-column joints with large size stiffened angles

        Peng Wang,Zhan Wang,Jianrong Pan,Bin Li,Bo Wang 국제구조공학회 2020 Steel and Composite Structures, An International J Vol.37 No.1

        The top-and-seat angles with double web angles are commonly used in the design of beam-to-column joints in Asian and North American countries. The seismic behavior analysis of these joints with large cross-section size of beam and column (often connected by four or more bolts) is a challenge due to the effects from the relatively larger size of stiffened angles and the composite action from the adjacent concrete slab. This paper presents an experimental investigation on the seismic performance of exterior composite beam-to-column joints with stiffened angles under cyclic loading. Four full-scale composite joints with different configuration (only one specimen contain top angle in concrete slab) were designed and tested. The joint specimens were designed by considering the effects of top angles, longitudinal reinforcement bars and arrangement of bolts. The behavior of the joints was carefully investigated, in terms of the failure modes, slippage, backbone curves, strength degradation, and energy dissipation abilities. It was found that the slippage between top-and-seat angles and beam flange, web angle and beam web led to a notable pinching effect, in addition, the ability of the energy dissipation was significantly reduced. The effect of anchored beams on the behavior of the joints was limited due to premature failure in concrete, the concrete slab that closes to the column flange and upper flange of beam plays an significant role when the joint subjected to the sagging moment. It is demonstrated that the ductility of the joints was significantly improved by the staggered bolts and welded longitudinal reinforcement bars.

      • Seismic behaviour of enlarged cross steel-reinforced concrete columns under various loadings

        Peng Wang,Qingxuan Shi,Feng Wang,Qiuwei Wang 국제구조공학회 2021 Steel and Composite Structures, An International J Vol.40 No.1

        Based on finite element software, a simulation programme is used to evaluate the seismic behaviour of new-type steel-reinforced concrete (SRC) columns, called enlarged cross steel-reinforced concrete (ECSRC) columns. With abundant simulations, the effects of the loading paths, number of loading cycles, incremental amplitude of displacement and variable axial load on the seismic response of the ECSRC columns were investigated. The results indicate that the seismic behaviour of the column is highly dependent on the loading paths, and it was observed that the loading paths produced a significant effect on the hysteretic response of the columns. Compared with those under uniaxial loading, the yield load, maximum load, ultimate displacement and ductility coefficient of the ECSRC columns under biaxial loading are reduced by 13.47%, 18.01%, 12.17% and 32.64%, respectively. The energy dissipation capacity of the columns is highly dependent on the loading paths. The skeleton curves are not significantly influenced by the number of loading cycles until the yield point of steel and longitudinal reinforcement is reached. With an increase in loading cycles, the yield load, yield displacement, ductility coefficient and maximum load, as well as the corresponding horizontal displacement of the column, are reduced, while the energy dissipation grows. In addition, the yield displacement, yield load, and ductility coefficient increase with an increase in the incremental amplitude of displacement; however, the energy dissipation decreases under these conditions. The seismic performance of the SRC column under variable axial loads clearly exhibits asymmetry that is worse than that observed under constant axial loads.

      • KCI등재

        Transcriptome profiling of indole-3-butyric acid-induced adventitious root formation in softwood cuttings of the Catalpa bungei variety ‘YU-1’ at different developmental stages

        Peng Wang,Ya Li,Lingling Ma,Shu’an Wang,Linfang Li,Rutong Yang,Yuzhu Ma,Qing Wang 한국유전학회 2016 Genes & Genomics Vol.38 No.2

        Catalpa bungei is a deciduous tree native to China. It is characterized as fast growing, being highly adaptable, and having excellent wood qualities. To better understand potential mechanisms involved in adventitious root (AR) formation, we performed transcriptome analysis of softwood cuttings of C. bungei ‘Yu-1’ at three stages of AR formation using the Illumina sequencing method. Following de novo assembly, 62,955 unigenes were obtained, 31,646 (50.26 %) of which were annotated. A total of 11,100 differentially expressed genes (DEGs), including 10,200 unique and 900 common, were identified in four comparisons. Based on the all GO enrichment networks, 46 common and 7 unique GO categories were identified. Cytoskeleton was only significantly enriched in the activation period, while DNA metabolic process was only significantly enriched in the callus formation. Functional annotation analysis revealed that many of these genes were involved in phenylpropanoid biosynthesis, glycolysis, and plant hormone metabolism, suggesting potential contributions to AR formation. Interestingly, the number of DEGs involved in glycolysis decreased while the number of DEGs involved in phenylpropanoid biosynthesis increased following the AR formative process. Overall, our comprehensive transcriptional overview will prove useful, not only in the understanding of molecular networks that regulate AR formation in C. bungei, but also for exploring genes that may improve rooting rates of other trees.

      • KCI등재

        Ball End Mill—Tool Radius Compensation of Complex NURBS Surfaces for 3-Axis CNC Milling Machines

        Zhaoqin Wang,Xiaorong Wang,Yusen Wang,Ruijun Wang,Manyu Bao,Tiesong Lin,Peng He 한국정밀공학회 2020 International Journal of Precision Engineering and Vol.21 No.8

        In order to extend the 2D-TRC (tool radius compensation) function of 3-axis CNC milling machines to ball end mills (BEMs), a new TRC named BEM-TRC is proposed to achieve successful milling of complex surfaces without over-cut. The implementation of the BEM-TRC for complex surfaces depicted in NURBS model is divided into three steps. The first one is to search the cutting point (CP) on a NURBS surface using equi-arc length interpolation in u or v direction. The second one is to accomplish BEM-TRC at the CP through offsetting the CP to the cutter center point (CCP) of a BEM along the normal vector at CP. The third one is to compute the cutter location point (CLP) of the BEM according to the BEM-CCP. The simulation and experiment verifies that the BEM-TRC is feasible and effective, and can avoid over-cut phenomenon successfully. The BEM-TRC extends the ability of the traditional 2D-TRC function, and makes 3-axis CNC milling machines to accomplish the milling process of complex NURBS surfaces.

      • KCI등재

        Intestinal Anti-Inflammatory Effects of Selenized Ulva pertusa Polysaccharides in a Dextran Sulfate Sodium-Induced Inflammatory Bowel Disease Model

        Yifan Wang,Han Ye,Leke Qiao,Chunying Du,Zhengpeng Wei,Ting Wang,Jingfeng Wang,Ruizhi Liu,Peng Wang 한국식품영양과학회 2021 Journal of medicinal food Vol.24 No.3

        The purpose of this study was to examine the alleviative effects of selenized polysaccharides from Ulva pertusa (ulvan-Se) on inflammatory bowel disease (IBD) in mice. The dextran sulfate sodium (DSS)-induced IBD mouse model was used to explore the protective effects of ulvan-Se on the intestinal mechanical and immune barrier. At doses less than 1208 mg/kg·bw ulvan-Se showed no significant damage to Institute of Cancer Research (ICR) mice in an acute toxicity test. The results showed that DSS destroyed the mechanical barrier, which includes epithelial cells, while ulvan-Se promoted mRNA expression of tight junction proteins (zonula occludens protein 1, occludin, and claudin-1) and inhibited the infiltration of white blood cells into the intestines. At 100 mg/kg·bw, ulvan-Se enhanced the antioxidant capacity of mice more effectively than the 50 mg/kg·bw ulvan-Se. Furthermore, ulvan-Se improved the intestinal immune barrier by increasing immunoglobulin A and immunoglobulin M, while regulating the levels of interleukin (IL)-1β, interferon-γ, and IL-4. Oral administration of ulvan-Se also suppressed tumor necrosis factor-α, IL-1β, IL-6, and cyclooxygenase-2 mRNA expression mediated by the nuclear factor kappa B pathway. Taken together, our findings reveal that ulvan-Se could be used as a potential alternative supplement for reducing intestinal inflammation in IBD.

      • KCI등재

        SIRT5-related desuccinylation modification of AIFM1 protects against compression-induced intervertebral disc degeneration by regulating mitochondrial homeostasis

        Mao Jianxin,Wang Di,Wang Dong,Wu Qi,Shang Qiliang,Gao Chu,Wang Huanbo,Wang Han,Du Mu,Peng Pandi,Jia Haoruo,Xu Xiaolong,Wang Jie,Yang Liu,Luo Zhuojing 생화학분자생물학회 2023 Experimental and molecular medicine Vol.55 No.-

        Mitochondrial dysfunction plays a major role in the development of intervertebral disc degeneration (IDD). Sirtuin 5 (SIRT5) participates in the maintenance of mitochondrial homeostasis through its desuccinylase activity. However, it is still unclear whether succinylation or SIRT5 is involved in the impairment of mitochondria and development of IDD induced by excessive mechanical stress. Our 4D label-free quantitative proteomic results showed decreased expression of the desuccinylase SIRT5 in rat nucleus pulposus (NP) tissues under mechanical loading. Overexpression of Sirt5 effectively alleviated, whereas knockdown of Sirt5 aggravated, the apoptosis and dysfunction of NP cells under mechanical stress, consistent with the more severe IDD phenotype of Sirt5 KO mice than wild-type mice that underwent lumbar spine instability (LSI) surgery. Moreover, immunoprecipitation-coupled mass spectrometry (IP-MS) results suggested that AIFM1 was a downstream target of SIRT5, which was verified by a Co-IP assay. We further demonstrated that reduced SIRT5 expression resulted in the increased succinylation of AIFM1, which in turn abolished the interaction between AIFM1 and CHCHD4 and thus led to the reduced electron transfer chain (ETC) complex subunits in NP cells. Reduced ETC complex subunits resulted in mitochondrial dysfunction and the subsequent occurrence of IDD under mechanical stress. Finally, we validated the efficacy of treatments targeting disrupted mitochondrial protein importation by upregulating SIRT5 expression or methylene blue (MB) administration in the compression-induced rat IDD model. In conclusion, our study provides new insights into the occurrence and development of IDD and offers promising therapeutic approaches for IDD.

      • KCI등재

        A putative plastidial adenine nucleotide transporter, BRITTLE1-3, plays an essential role in regulating chloroplast development in rice (Oryza sativa L.)

        Jia Lyu,Yihua Wang,Linglong Liu,Chunming Wang,Yulong Ren,Cheng Peng,Feng Liu,Yunlong Wang,Mei Niu,Di Wang,Ming Zheng,Kunneng Zhou,Shaolu Zhao,Fuqing Wu,Haiyang Wang,Jianmin Wan 한국식물학회 2017 Journal of Plant Biology Vol.60 No.5

        Differentiation from proplastids into chloroplasts isa light- and energy-dependent process. How this process isregulated is still poorly understood at the molecular level. We herein report a new putative plastidial adenine nucleotidetransporter, BRITTLE1-3 (referred to as OsBT1-3), encoded bythe rice (Oryza sativa) White Stripe Leaf 2 (WSL2) gene. Loss of OsBT1-3 function results in defective chloroplastbiogenesis, severely reduced photosynthetic efficiency, andfinally a white stripe leaf phenotype in the first four leaves. The expression levels of genes related to chlorophyllbiosynthesis and photosynthesis are drastically reduced,accompanied with over accumulation of reactive oxygenspecies (ROS) in the wsl2 mutant. OsBT1-3 is targeted tothe chloroplasts and it expresses in almost all tissues inplants, especially in young leaves. OsBT1-3 consists of 419amino acids and exhibits features of all mitochondrialcarrier proteins, including a typical transmembrane-spanningdomain and a highly conserved sequence motif designatedas the ‘mitochondrial energy transfer signatures’. Phylogeneticanalysis shows that OsBT1-3 is a putative plastidialadenine nucleotide transporter and is most closely relatedto ZmBT1-2. Together, these observations suggest that thenew putative adenine nucleotide transporter, OsBT1-3,plays an essential role in regulating chloroplast biogenesisand maintenance of ROS homeostasis during rice seedlingde-etiolation.

      • KCI등재

        Green-revertible Chlorina 1 (grc1) is Required for the Biosynthesis of Chlorophyll and the Early Development of Chloroplasts in Rice

        Jieqin Li,Yihua Wang,Juntao Chai,Lihua Wang,Chunming Wang,Wuhua Long,Di Wang,Yunlong Wang,Ming Zheng,Cheng Peng,Mei Niu,Jianmin Wan 한국식물학회 2013 Journal of Plant Biology Vol.56 No.5

        The nuclear genes involved in chloroplast developmentand chlorophyll biosynthesis must be investigated tounderstand their functions in plant growth and development. In this study, we isolated and identified a unique leaf-colormutant of rice with a green-yellow phenotype before thefour-leaf stage and named the mutation green-revertiblechlorina 1 (grc1). The mutants had significantly lower plantheight, number of tillers, and panicle length and headedsignificantly earlier than the wild type. The levels ofchlorophylls, carotenoids, and chlorophyll precursors werealso lower. The mutation in grc1 affected chloroplastultrastructure, particularly thylakoid development. Geneticanalysis indicated that the green-yellow phenotype wascontrolled by a single recessive gene. We mapped the grc1gene to a 32.4-kb region on the long arm of chromosome 6. Through map-based cloning, we identified a 45-bp insertionin the genomic region of LOC_Os06g40080, which encodeda heme oxygenase. Expression of LOC_Os06g40080 wassignificantly down-regulated in the grc1 mutant. Subcellularlocalization showed that this heme oxygenase was localizedin the chloroplast. In summary, we isolated and identified thegene for grc1, which plays an important role in chlorophyllbiosynthesis and chloroplast development in rice.

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