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Plasmapheresis in a Patient With "Refractory" Urticarial Vasculitis
Ozgur Kartal,Mustafa Gulec,Zafer Caliskaner,Oral Nevruz,Turker Cetin,Osman Sener 대한천식알레르기학회 2012 Allergy, Asthma & Immunology Research Vol.4 No.4
Immune complexes are found in the circulation of 30%-75% of patients with urticarial vasculitis and much evidence supports the role of these immune complexes in the pathogenesis of urticarial vasculitis. Plasmapheresis is effective for removing these immune complexes; however, there are few reports on the use of plasmapheresis in the treatment of urticarial vasculitis. We describe a case of “refractory” urticarial vasculitis in which the symptoms improved after plasmapheresis treatment. We suggest that plasmapheresis be considered as an option in patients with severe or treatment-resistant urticarial vasculitis.
Acute Generalized exanthematous pustulosis Due to oral Use of Blue Dyes
( Osman Sener ),( Osman Kose ),( Ozgur Kartal ),( Mukerrem Safali ) 대한내과학회 2011 The Korean Journal of Internal Medicine Vol.26 No.3
Acute generalized exanthematous pustulosis is a rare severe pustular cutaneous adverse reaction characterized by a rapid clinical course with typical histological findings. It is accompanied by fever and acute eruption of non-follicular pustules overlying erythrodermic skin. The causative agents are most frequently antibacterial drugs. We present a patient with acute generalized exanthematous pustulosis caused by methylene blue and indigotin dyes.
A New Approach to Objective Evaluation of the Success of Nasal Septum Perforation
Ozturk, Sinan,Zor, Fatih,Ozturk, Serdar,Kartal, Ozgur,Alhan, Dogan,Isik, Selcuk Korean Society of Plastic and Reconstructive Surge 2014 Archives of Plastic Surgery Vol.41 No.4
Background Perforations in the nasal septum (NSP) give rise not only to disintegration of the septum anatomy but also impairment in normal nasal physiology. The successes of these surgical techniques are usually equated to anatomical closure of the perforation. The goal of this study is to evaluate the subjective and objective results of our surgical technique for septal perforation surgery. Methods All NSPs in the six patients were closed by inferior turbinate flap. The Nasal Obstruction Symptom Evaluation (NOSE) instrument was used to evaluate the preoperative and postoperative subjective sensation of nasal obstruction. Measurement of preoperative and postoperative nasal airway resistance was performed using active anterior rhinomanometry which is an objective test. Wilcoxson signed rank test and Spearman correlation test were used to analyze correlation between NOSE scores and rhinomanometric measurements. Results The full closure of the septal perforations was noted in 100% of patients. The total NOSE score was 14 preoperatively and one postoperatively. The improvement in NOSE scores was statistically significant ($P{\leq}0.002$). The mean preoperative total resistance (ResT150) value was $0.13Pa/cm^3s^{-1}$, which is below the normal range ($0.16-0.31Pa/cm^3s^{-1}$), while the mean postoperative ResT150 value was $0.27Pa/cm^3s^{-1}$. The correlation between the improvement in NOSE scores and improvements in ResT150 values was statistically significant. Conclusions Surgical approaches should aim to solve both the anatomical and physiological problems of NSP. The application of subjective and objective tests in the postoperative period will help surgeons assess the applied techniques.
A New Approach to Objective Evaluation of the Success of Nasal Septum Perforation
Sinan Ozturk,Fatih Zor,Serdar Ozturk,Ozgur Kartal,Dogan Alhan,Selcuk Isik 대한성형외과학회 2014 Archives of Plastic Surgery Vol.41 No.4
Background: Perforations in the nasal septum (NSP) give rise not only to disintegration ofthe septum anatomy but also impairment in normal nasal physiology. The successes of thesesurgical techniques are usually equated to anatomical closure of the perforation. The goal ofthis study is to evaluate the subjective and objective results of our surgical technique forseptal perforation surgery. Methods: All NSPs in the six patients were closed by inferior turbinate flap. The NasalObstruction Symptom Evaluation (NOSE) instrument was used to evaluate the preoperativeand postoperative subjective sensation of nasal obstruction. Measurement of preoperative andpostoperative nasal airway resistance was performed using active anterior rhinomanometrywhich is an objective test. Wilcoxson signed rank test and Spearman correlation test were usedto analyze correlation between NOSE scores and rhinomanometric measurements. Results: The full closure of the septal perforations was noted in 100% of patients. The totalNOSE score was 14 preoperatively and one postoperatively. The improvement in NOSE scoreswas statistically significant (P≤0.002). The mean preoperative total resistance (ResT150) valuewas 0.13 Pa/cm3s-1, which is below the normal range (0.16–0.31 Pa/cm3s-1), while the meanpostoperative ResT150 value was 0.27 Pa/cm3s-1. The correlation between the improvement inNOSE scores and improvements in ResT150 values was statistically significant . Conclusions: Surgical approaches should aim to solve both the anatomical and physiologicalproblems of NSP. The application of subjective and objective tests in the postoperative periodwill help surgeons assess the applied techniques.